RU2301063C9 - Форма для трансэпикутанного введения для лечения синдрома усталых ног - Google Patents
Форма для трансэпикутанного введения для лечения синдрома усталых ногInfo
- Publication number
- RU2301063C9 RU2301063C9 RU2004131866/15A RU2004131866A RU2301063C9 RU 2301063 C9 RU2301063 C9 RU 2301063C9 RU 2004131866/15 A RU2004131866/15 A RU 2004131866/15A RU 2004131866 A RU2004131866 A RU 2004131866A RU 2301063 C9 RU2301063 C9 RU 2301063C9
- Authority
- RU
- Russia
- Prior art keywords
- tds
- use according
- acrylate
- amino
- ethyl
- Prior art date
Links
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- 230000002035 prolonged effect Effects 0.000 description 1
- 230000002685 pulmonary effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
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- 239000011347 resin Substances 0.000 description 1
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- 229960001879 ropinirole Drugs 0.000 description 1
- UHSKFQJFRQCDBE-UHFFFAOYSA-N ropinirole Chemical compound CCCN(CCC)CCC1=CC=CC2=C1CC(=O)N2 UHSKFQJFRQCDBE-UHFFFAOYSA-N 0.000 description 1
- 230000003248 secreting effect Effects 0.000 description 1
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- 229920002050 silicone resin Polymers 0.000 description 1
- 230000003860 sleep quality Effects 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- HRZFUMHJMZEROT-UHFFFAOYSA-L sodium disulfite Chemical compound [Na+].[Na+].[O-]S(=O)S([O-])(=O)=O HRZFUMHJMZEROT-UHFFFAOYSA-L 0.000 description 1
- 235000010267 sodium hydrogen sulphite Nutrition 0.000 description 1
- 229940001584 sodium metabisulfite Drugs 0.000 description 1
- 235000010262 sodium metabisulphite Nutrition 0.000 description 1
- 235000019795 sodium metasilicate Nutrition 0.000 description 1
- 239000012064 sodium phosphate buffer Substances 0.000 description 1
- NTHWMYGWWRZVTN-UHFFFAOYSA-N sodium silicate Chemical compound [Na+].[Na+].[O-][Si]([O-])=O NTHWMYGWWRZVTN-UHFFFAOYSA-N 0.000 description 1
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- 238000010972 statistical evaluation Methods 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10220230.3 | 2002-05-06 | ||
| DE10220230A DE10220230A1 (de) | 2002-05-06 | 2002-05-06 | Verwendung von Rotigotine zur Behandlung des Restless Leg Syndroms |
Publications (3)
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| RU2004131866A RU2004131866A (ru) | 2005-06-10 |
| RU2301063C2 RU2301063C2 (ru) | 2007-06-20 |
| RU2301063C9 true RU2301063C9 (ru) | 2007-11-27 |
Family
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| RU2004131866/15A RU2301063C9 (ru) | 2002-05-06 | 2003-05-05 | Форма для трансэпикутанного введения для лечения синдрома усталых ног |
Country Status (23)
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| EP (1) | EP1501499B1 (enExample) |
| JP (2) | JP5253707B2 (enExample) |
| KR (1) | KR20040104697A (enExample) |
| CN (1) | CN100396281C (enExample) |
| AT (1) | ATE387912T1 (enExample) |
| AU (1) | AU2003233233B2 (enExample) |
| BR (1) | BR0309837A (enExample) |
| CA (2) | CA2483120C (enExample) |
| CY (1) | CY1107452T1 (enExample) |
| DE (2) | DE10220230A1 (enExample) |
| DK (1) | DK1501499T3 (enExample) |
| ES (1) | ES2301795T3 (enExample) |
| IL (2) | IL164861A0 (enExample) |
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| NO (1) | NO333619B1 (enExample) |
| NZ (1) | NZ536533A (enExample) |
| PL (1) | PL218549B1 (enExample) |
| PT (1) | PT1501499E (enExample) |
| RU (1) | RU2301063C9 (enExample) |
| SI (1) | SI1501499T1 (enExample) |
| UA (1) | UA81625C2 (enExample) |
| WO (1) | WO2003092677A1 (enExample) |
| ZA (1) | ZA200408862B (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10041478A1 (de) | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung |
| DE10359528A1 (de) * | 2003-12-18 | 2005-07-28 | Schwarz Pharma Ag | (S)-2-N-Propylamino-5-hydroxytetralin als D3-agonistisches Therapeutikum |
| ES2466647T3 (es) * | 2006-05-08 | 2014-06-10 | Teikoku Seiyaku Co., Ltd. | Preparación absorbible por vía transdérmica que comprende un agente contra la demencia |
| TWI392670B (zh) * | 2006-06-22 | 2013-04-11 | Ucb Pharma Gmbh | 經取代的２-胺基萘滿之於製造用於預防、減緩及／或治療各種類型疼痛之藥物上的用途 |
| EP1987815A1 (en) * | 2007-05-04 | 2008-11-05 | Schwarz Pharma Ag | Oronasopharyngeally deliverable pharmaceutical compositions of dopamine agonists for the prevention and/or treatment of restless limb disorders |
| MY165575A (en) | 2007-11-28 | 2018-04-05 | Ucb Pharma Gmbh | Polymorphic form of rotigotine |
| US20110028880A1 (en) | 2008-02-27 | 2011-02-03 | Hisamitsu Pharmaceutical Co., Inc. | Patch |
| JP5546013B2 (ja) | 2008-02-27 | 2014-07-09 | 久光製薬株式会社 | 貼付剤及び包装体 |
| EP2201941A1 (de) | 2008-12-29 | 2010-06-30 | UCB Pharma GmbH | Pflaster-Herstellungstechnologie |
| EP2281559A1 (en) | 2009-06-26 | 2011-02-09 | UCB Pharma GmbH | Pharmaceutical composition comprising rotigotine salts (acid or Na), especially for iontophoresis |
| CN102665699A (zh) | 2009-12-22 | 2012-09-12 | 优时比制药有限公司 | 用于使非结晶形式的罗替戈汀的固体分散体稳定化的聚乙烯吡咯烷酮 |
| US8729306B2 (en) | 2010-02-05 | 2014-05-20 | Ucb Pharma Gmbh | Process for the preparation of nitrogen substituted aminotetralins derivatives |
| BR112012029944A2 (pt) | 2010-06-25 | 2019-09-24 | Ucb Pharma Gmbh | processo para preparação de derivados de aminotetralinas substituídas com nitrogênio |
| EP2559435A1 (en) | 2011-08-19 | 2013-02-20 | UCB Pharma GmbH | Rotigotine in the treatment of hemispatial neglect, stroke and deficits following stroke |
| DE102012013439A1 (de) | 2012-07-03 | 2014-01-23 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermales therapeutisches System umfassend Rotigotin und Kristallisationsinhibitor |
| WO2013075823A1 (en) | 2011-11-22 | 2013-05-30 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermal therapeutic system comprising rotigotine and crystallization inhibitor |
| DE102012013421A1 (de) | 2012-07-03 | 2014-01-09 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermales therapeutisches System (TTS) mit Rotigotin |
| KR101558042B1 (ko) * | 2012-07-05 | 2015-10-07 | 에스케이케미칼주식회사 | 로티고틴을 함유한 경피흡수제제 |
| EP2870963A4 (en) * | 2012-07-06 | 2016-03-09 | Sk Chemicals Co Ltd | PREPARATION CONTAINING ROTIGOTINE FOR PERCUTANEOUS ABSORBING |
| TW201431570A (zh) | 2012-11-22 | 2014-08-16 | Ucb Pharma Gmbh | 用於經皮投服羅替戈汀（Ｒｏｔｉｇｏｔｉｎｅ）之多天式貼片 |
| CA2916183C (en) | 2013-07-03 | 2022-03-29 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system with electronic component |
| MX2016011152A (es) | 2014-02-27 | 2016-12-09 | Medrx Co Ltd | Parche transdermico que contiene pramipexol para tratamiento de enfermedad neurodegenerativa. |
| US11752110B2 (en) | 2014-05-20 | 2023-09-12 | Lts Lohmann Therapie-Systeme Ag | Transdermal delivery system including an interface mediator |
| JP6573913B2 (ja) | 2014-05-20 | 2019-09-11 | エルテーエス ローマン テラピー−ジステーメ アーゲー | ロチゴチンを含む経皮送達システム |
| CA2948219C (en) | 2014-05-20 | 2023-04-04 | Lts Lohmann Therapie-Systeme Ag | Method for adjusting the release of active agent in a transdermal delivery system |
| KR102401412B1 (ko) | 2019-06-14 | 2022-05-23 | 히사미쓰 세이야꾸 가부시키가이샤 | 로티고틴 함유 첩부제 |
| FI3854388T3 (fi) | 2020-01-24 | 2023-11-27 | Luye Pharma Switzerland Ag | Transdermaalinen hoitojärjestelmä, jossa on vaikuttava aine rotigotiini ja ainakin yksi ei-amiiniresistentti silikoniliima |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5658975A (en) * | 1994-01-14 | 1997-08-19 | Dow Corning Corporation | Hot-melt silicone pressure sensitive adhesive with siloxylated polyether waxes as additives |
| RU2108812C1 (ru) * | 1992-11-12 | 1998-04-20 | Клинге Фарма ГмбХ | Трансдермальная терапевтическая система и способ ее получения |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US5474783A (en) * | 1988-03-04 | 1995-12-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
| US5656286A (en) * | 1988-03-04 | 1997-08-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
| US5232702A (en) * | 1991-07-22 | 1993-08-03 | Dow Corning Corporation | Silicone pressure sensitive adhesive compositons for transdermal drug delivery devices and related medical devices |
| IL116539A (en) * | 1995-01-06 | 2002-02-10 | Noven Pharma | Preparations given through the skin of unstable anti-acid drugs |
| FR2749514B1 (fr) * | 1996-06-11 | 1998-08-07 | Hoechst Marion Roussel | Systemes transdermiques renfermant 2 principes actifs dans des compartiments separes, leur procede de preparation et leur application comme medicament |
| DE19701619B4 (de) * | 1997-01-17 | 2007-10-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verwendung von Pramipexol zur Behandlung des restless legs syndroms |
| DE19814084B4 (de) * | 1998-03-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung |
| DE19938825A1 (de) * | 1999-08-19 | 2001-04-26 | Boehringer Ingelheim Pharma | Wirkstoffkombination mit Clonidin |
| DE19938823A1 (de) * | 1999-08-19 | 2001-02-22 | Boehringer Ingelheim Pharma | Medikamentöse Behandlung des Restless Leg Syndroms |
| DE10041479A1 (de) * | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung zur Verabreichung von N-0923 |
| ES2203563T3 (es) * | 2001-05-08 | 2004-04-16 | Schwarz Pharma Ag | Sistema terapeutico transdermico mejorado para el tratamiento de la enfermedad de parkinson. |
| DK1256339T3 (da) * | 2001-05-08 | 2004-02-09 | Sanol Arznei Schwarz Gmbh | Transdermalt terapeutisk system for opnåelse af høje plasmaniveauer af rotigotin i behandlingen af Parkinsons sygdom |
-
2002
- 2002-05-06 DE DE10220230A patent/DE10220230A1/de not_active Ceased
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2003
- 2003-05-05 RU RU2004131866/15A patent/RU2301063C9/ru active
- 2003-05-05 SI SI200331195T patent/SI1501499T1/sl unknown
- 2003-05-05 CA CA2483120A patent/CA2483120C/en not_active Expired - Fee Related
- 2003-05-05 PT PT03727432T patent/PT1501499E/pt unknown
- 2003-05-05 KR KR10-2004-7017685A patent/KR20040104697A/ko not_active Ceased
- 2003-05-05 WO PCT/EP2003/004685 patent/WO2003092677A1/de not_active Ceased
- 2003-05-05 DE DE50309318T patent/DE50309318D1/de not_active Expired - Lifetime
- 2003-05-05 IL IL16486103A patent/IL164861A0/xx unknown
- 2003-05-05 NZ NZ536533A patent/NZ536533A/en not_active IP Right Cessation
- 2003-05-05 UA UA20041109078A patent/UA81625C2/ru unknown
- 2003-05-05 AT AT03727432T patent/ATE387912T1/de active
- 2003-05-05 PL PL373276A patent/PL218549B1/pl unknown
- 2003-05-05 CN CNB038160250A patent/CN100396281C/zh not_active Expired - Fee Related
- 2003-05-05 CA CA2787384A patent/CA2787384A1/en not_active Abandoned
- 2003-05-05 MX MXPA04010687A patent/MXPA04010687A/es active IP Right Grant
- 2003-05-05 ES ES03727432T patent/ES2301795T3/es not_active Expired - Lifetime
- 2003-05-05 DK DK03727432T patent/DK1501499T3/da active
- 2003-05-05 AU AU2003233233A patent/AU2003233233B2/en not_active Ceased
- 2003-05-05 BR BR0309837-0A patent/BR0309837A/pt not_active Application Discontinuation
- 2003-05-05 EP EP03727432A patent/EP1501499B1/de not_active Revoked
- 2003-05-05 JP JP2004500861A patent/JP5253707B2/ja not_active Expired - Lifetime
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2004
- 2004-10-27 IL IL164861A patent/IL164861A/en active IP Right Grant
- 2004-11-02 ZA ZA2004/08862A patent/ZA200408862B/en unknown
- 2004-11-30 NO NO20045240A patent/NO333619B1/no not_active IP Right Cessation
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2008
- 2008-05-02 CY CY20081100471T patent/CY1107452T1/el unknown
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2010
- 2010-04-22 JP JP2010098924A patent/JP2010159302A/ja active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| RU2108812C1 (ru) * | 1992-11-12 | 1998-04-20 | Клинге Фарма ГмбХ | Трансдермальная терапевтическая система и способ ее получения |
| US5658975A (en) * | 1994-01-14 | 1997-08-19 | Dow Corning Corporation | Hot-melt silicone pressure sensitive adhesive with siloxylated polyether waxes as additives |
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| METMAN L.V. ET AL. Continuous transdermal dopaminergic stimulation in advanced Parkinson, s disease, Clin Neurophamacol, 2001 May-Jun; 24(3):163-9 (реферат) Pub-Med. Stiasny K. ET AL. Treatment of idiopathic restless legs syndrome (RLS) with the D2-agonist cabergoline-an open clinical trial, Sleep. 2000 May 1;23(3):349-54 (реферат) Pub-Med. * |
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| TH4A | Reissue of patent specification | ||
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Effective date: 20110713 |