RU2293117C2 - Ген streptomyces avermitilis и его применение для изменения соотношения авермектинов b2:b1 - Google Patents
Ген streptomyces avermitilis и его применение для изменения соотношения авермектинов b2:b1 Download PDFInfo
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- RU2293117C2 RU2293117C2 RU2004124521/13A RU2004124521A RU2293117C2 RU 2293117 C2 RU2293117 C2 RU 2293117C2 RU 2004124521/13 A RU2004124521/13 A RU 2004124521/13A RU 2004124521 A RU2004124521 A RU 2004124521A RU 2293117 C2 RU2293117 C2 RU 2293117C2
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- avermectins
- amino acid
- avermitilis
- cyclohexyl
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US35622202P | 2002-02-12 | 2002-02-12 | |
| US60/356,222 | 2002-02-12 |
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| Publication Number | Publication Date |
|---|---|
| RU2004124521A RU2004124521A (ru) | 2005-04-10 |
| RU2293117C2 true RU2293117C2 (ru) | 2007-02-10 |
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| Application Number | Title | Priority Date | Filing Date |
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| RU2004124521/13A RU2293117C2 (ru) | 2002-02-12 | 2003-01-31 | Ген streptomyces avermitilis и его применение для изменения соотношения авермектинов b2:b1 |
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| Country | Link |
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| US (2) | US7388085B2 (enExample) |
| EP (2) | EP2050815B1 (enExample) |
| JP (1) | JP2005517406A (enExample) |
| KR (1) | KR100718378B1 (enExample) |
| CN (2) | CN1630712B (enExample) |
| AR (1) | AR038405A1 (enExample) |
| AT (2) | ATE530645T1 (enExample) |
| AU (1) | AU2003245052B2 (enExample) |
| BR (1) | BRPI0307620B8 (enExample) |
| CA (1) | CA2475214C (enExample) |
| CY (2) | CY1110454T1 (enExample) |
| DE (1) | DE60326824D1 (enExample) |
| DK (2) | DK2050815T3 (enExample) |
| ES (2) | ES2321827T3 (enExample) |
| IL (3) | IL162866A0 (enExample) |
| ME (1) | ME00472B (enExample) |
| MX (1) | MXPA04007777A (enExample) |
| PL (1) | PL211693B1 (enExample) |
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| RS (1) | RS50813B (enExample) |
| RU (1) | RU2293117C2 (enExample) |
| SI (2) | SI2050815T1 (enExample) |
| TW (1) | TWI341330B (enExample) |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2321827T3 (es) * | 2002-02-12 | 2009-06-12 | Pfizer Products Inc. | Gen de streptomyces avermitilis que rige la relacion de avermectinas b2-b1. |
| CN102241750B (zh) * | 2010-05-14 | 2014-05-28 | 中国科学院微生物研究所 | 一种生产阿维菌素的基因工程方法及其专用菌株 |
| CN102093997B (zh) * | 2010-12-01 | 2013-03-13 | 中国科学院上海有机化学研究所 | 一种改造除虫链霉菌产生多拉菌素的方法 |
| CN109576196B (zh) * | 2019-01-25 | 2022-01-04 | 北大方正集团有限公司 | 一种生产多拉菌素的发酵培养基及多拉菌素的生产方法 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999041389A1 (en) * | 1998-02-13 | 1999-08-19 | Pfizer Products Inc. | Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins |
| RU98110940A (ru) * | 1998-06-09 | 2000-07-20 | В.А. Мосин | Штамм streptomyces avermitilis ссм 4697, способ выделения авермектиновых комплексов и препараты для защиты животных и растений |
| WO2001012821A1 (en) * | 1999-08-12 | 2001-02-22 | Pfizer Products Inc. | Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE434277B (sv) | 1976-04-19 | 1984-07-16 | Merck & Co Inc | Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis |
| US4429042A (en) | 1978-09-08 | 1984-01-31 | Merck & Co., Inc. | Strain of Streptomyces for producing antiparasitic compounds |
| IN167980B (enExample) | 1987-01-23 | 1991-01-19 | Pfizer | |
| US5252474A (en) | 1989-03-31 | 1993-10-12 | Merck & Co., Inc. | Cloning genes from Streptomyces avermitilis for avermectin biosynthesis and the methods for their use |
| CZ287404B6 (en) * | 1993-10-05 | 2000-11-15 | Pfizer | Process for preparing doramectin |
| US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
| US6117679A (en) | 1994-02-17 | 2000-09-12 | Maxygen, Inc. | Methods for generating polynucleotides having desired characteristics by iterative selection and recombination |
| US5837458A (en) | 1994-02-17 | 1998-11-17 | Maxygen, Inc. | Methods and compositions for cellular and metabolic engineering |
| US6248579B1 (en) * | 1998-02-13 | 2001-06-19 | Pfizer Inc | Streptomyces avermitilis gene directing the ratio of B2:B1 avermectins |
| RU2156301C2 (ru) * | 1998-06-09 | 2000-09-20 | Мосин Владимир Александрович | Штамм актиномицета streptomyces avermitilis ссм 4697 - продуцент авермектинов |
| US6197591B1 (en) | 1998-09-14 | 2001-03-06 | Pfizer Inc. | Streptomyces avermitilis regulatory genes for increased avermectin production |
| NZ517694A (en) | 1999-08-13 | 2005-03-24 | Vertex Pharma | Inhibitors of c-Jun N-terminal kinases (JNK) and other protein kinases |
| ES2321827T3 (es) * | 2002-02-12 | 2009-06-12 | Pfizer Products Inc. | Gen de streptomyces avermitilis que rige la relacion de avermectinas b2-b1. |
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- 2003-01-31 AU AU2003245052A patent/AU2003245052B2/en not_active Expired
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- 2003-01-31 SI SI200332087T patent/SI2050815T1/sl unknown
- 2003-01-31 PL PL371320A patent/PL211693B1/pl unknown
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- 2003-01-31 RU RU2004124521/13A patent/RU2293117C2/ru active
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- 2003-01-31 DK DK09150098.3T patent/DK2050815T3/da active
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- 2003-01-31 CN CN038037416A patent/CN1630712B/zh not_active Expired - Lifetime
- 2003-01-31 AT AT09150098T patent/ATE530645T1/de active
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- 2003-01-31 KR KR1020047012437A patent/KR100718378B1/ko not_active Expired - Lifetime
- 2003-01-31 AT AT03739390T patent/ATE426659T1/de active
- 2003-01-31 JP JP2003568070A patent/JP2005517406A/ja active Pending
- 2003-01-31 MX MXPA04007777A patent/MXPA04007777A/es active IP Right Grant
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- 2003-02-10 US US10/361,376 patent/US7388085B2/en not_active Expired - Lifetime
- 2003-02-10 AR ARP030100408A patent/AR038405A1/es active IP Right Grant
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2004
- 2004-07-05 IL IL162866A patent/IL162866A/en active IP Right Grant
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2008
- 2008-04-23 US US12/107,949 patent/US8008078B2/en not_active Expired - Fee Related
- 2008-06-22 IL IL192371A patent/IL192371A/en active IP Right Grant
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2009
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- 2011-12-02 CY CY20111101193T patent/CY1112491T1/el unknown
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999041389A1 (en) * | 1998-02-13 | 1999-08-19 | Pfizer Products Inc. | Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins |
| RU98110940A (ru) * | 1998-06-09 | 2000-07-20 | В.А. Мосин | Штамм streptomyces avermitilis ссм 4697, способ выделения авермектиновых комплексов и препараты для защиты животных и растений |
| WO2001012821A1 (en) * | 1999-08-12 | 2001-02-22 | Pfizer Products Inc. | Streptomyces avermitilis gene directing the ratio of b2:b1 avermectins |
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