RU2291689C2 - Композиции n-ацетилцистеина и способы лечения и профилактики токсичности лекарственных средств - Google Patents
Композиции n-ацетилцистеина и способы лечения и профилактики токсичности лекарственных средств Download PDFInfo
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- RU2291689C2 RU2291689C2 RU2003131876/15A RU2003131876A RU2291689C2 RU 2291689 C2 RU2291689 C2 RU 2291689C2 RU 2003131876/15 A RU2003131876/15 A RU 2003131876/15A RU 2003131876 A RU2003131876 A RU 2003131876A RU 2291689 C2 RU2291689 C2 RU 2291689C2
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- Prior art keywords
- acetylcysteine
- therapeutic
- acetaminophen
- combination
- pharmaceutically acceptable
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Landscapes
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2013006658A1 (en) * | 2011-07-05 | 2013-01-10 | The Brigham And Women's Hospital, Inc. | Treatment of acetaminophen-induced liver damage by the administration of modulators of nitric oxide |
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| US7662863B2 (en) * | 2003-06-09 | 2010-02-16 | Alan Andrews | Therapeutic agent for the use in reducing alcohol intoxication and reducing or eliminating the negative side effects associated with alcohol ingestion |
| ES2819303T3 (es) | 2005-04-05 | 2021-04-15 | Univ Yale | Agentes moduladores del glutamato en el tratamiento de trastornos mentales |
| US8993627B2 (en) | 2005-04-21 | 2015-03-31 | Sentient Lifesciences, Inc. | N-acetylcysteine amide (NAC amide) for the treatment of diseases and conditions associated with oxidative stress |
| US8148356B2 (en) | 2005-08-24 | 2012-04-03 | Cumberland Pharmaceuticals, Inc. | Acetylcysteine composition and uses therefor |
| RU2302236C2 (ru) * | 2005-09-09 | 2007-07-10 | Государственное учреждение научно-исследовательский институт Гриппа Российской академии медицинских наук (ГУ НИИ Гриппа РАМН) | Средство, обладающее антигипоксической и цитопротекторной активностями, используемое для снижения токсичности ремантадина при лечении гриппозной инфекции |
| US20070098790A1 (en) * | 2005-10-31 | 2007-05-03 | David Jiang | Nutritional supplement for the enhancement of the health of the liver |
| US20080139654A1 (en) * | 2006-12-09 | 2008-06-12 | Eric Mott Soderling | Acetaminophen compositions having minimized side effects including reduced hepatotoxicity |
| CN102088965B (zh) * | 2008-05-13 | 2013-05-08 | 根梅迪卡治疗公司 | 水杨酸盐(酯)缀合物在制备用于治疗代谢性病症的药物中的应用 |
| CN102421424A (zh) * | 2009-03-16 | 2012-04-18 | 根梅迪卡治疗公司 | 用于治疗代谢性疾病的组合疗法 |
| JP2012520342A (ja) * | 2009-03-16 | 2012-09-06 | ジェンメディカ・セラピューティックス・ソシエダッド・リミターダ | 代謝障害を処置するのに有用な抗炎症剤および抗酸化剤のコンジュゲート |
| WO2010132864A1 (en) * | 2009-05-15 | 2010-11-18 | Intermune, Inc. | Methods of treating hiv patients with anti-fibrotics |
| US20120122787A1 (en) * | 2009-07-10 | 2012-05-17 | Rong Li | Methods for treating polycystic kidney disease (pkd) or other cyst forming diseases |
| CN102573463A (zh) * | 2009-07-15 | 2012-07-11 | 小利兰·斯坦福大学托管委员会 | N-乙酰半胱氨酸组合物以及改善对乙酰氨基酚的治疗效能的方法 |
| DE102011006425A1 (de) | 2010-03-31 | 2011-10-06 | Awd.Pharma Gmbh & Co. Kg | Pharmazeutische Zubereitung und deren Verwendung |
| US8466197B2 (en) | 2010-12-14 | 2013-06-18 | Genmedica Therapeutics Sl | Thiocarbonates as anti-inflammatory and antioxidant compounds useful for treating metabolic disorders |
| US8747894B2 (en) | 2012-05-08 | 2014-06-10 | Alpex Pharma S.A. | Effervescent compositions containing N-acetylcysteine |
| WO2013175479A1 (en) | 2012-05-24 | 2013-11-28 | Hadasit Medical Research Services And Development Ltd. | Compositions comprising isosilybin b for amelioration and prevention of drug- induced toxicity |
| EA201990684A1 (ru) | 2013-12-24 | 2020-12-30 | Вирджиния Коммонвелт Юниверсити | Способы применения оксигенированных холестеролсульфатов (ocs) |
| PE20180026A1 (es) | 2015-01-27 | 2018-01-09 | Florengale Llc | Composicion topica curativa |
| EP3302580B1 (en) | 2015-05-27 | 2021-01-20 | University of Pittsburgh - Of the Commonwealth System of Higher Education | Compositions and methods for reducing the risk of post-imaging pancreatitis |
| JP7074663B6 (ja) * | 2015-05-28 | 2022-08-01 | ベイラー カレッジ オブ メディスン | グルタチオンレベルを改善するためのｎ－アセチルシステイン及びグリシンの補給の効果 |
| JP7311267B2 (ja) * | 2016-01-11 | 2023-07-19 | エゲティス・セラピューティクス・アーベー | 急性肝不全及び他の肝毒性状態を治療及び／又はこれらから保護するための方法及び製剤 |
| CN115154619B (zh) * | 2016-02-04 | 2025-11-28 | 西泽普研究与发展有限责任公司 | 受控释放和层状的环糊精包合物媒介物 |
| EA201991331A1 (ru) | 2016-12-15 | 2019-11-29 | N-ацетилцистеин для применения в качестве антибактериального агента | |
| US11040007B2 (en) * | 2017-01-24 | 2021-06-22 | Woosung Pharmaceutical Co., Ltd. | Injection composition containing acetaminophen |
| WO2020129509A1 (ja) * | 2018-12-21 | 2020-06-25 | 富士フイルム株式会社 | 光毒性または光アレルギーの測定方法および上記測定方法において使用するための試薬 |
| US11590090B2 (en) | 2019-09-14 | 2023-02-28 | Anzen Pharmaceuticals, LLC | Acetaminophen formulation with protection against toxic effects of overdose |
| GB2588172B (en) * | 2019-10-11 | 2023-05-24 | Blackhawk Partners Ltd | A pharmaceutical composition comprising cannabinoid |
| CN113288890B (zh) * | 2021-06-21 | 2022-02-22 | 南方医科大学南方医院 | N-乙酰-l-半胱氨酸在制备预防和/或治疗运动损伤的药物中的应用 |
| US12357667B2 (en) | 2021-07-28 | 2025-07-15 | Pono Lifestyle, Llc | Nutraceutical formulations to prevent, treat, and inhibit excess cytokines, SARS-CoV-2 spike proteins, and mRNA vaccine spike proteins |
| EP4238559A1 (en) | 2022-03-04 | 2023-09-06 | Centre Hospitalier Universitaire de Caen Normandie | Combinations of acetaminophen and n-acetyl cysteine for the treatment of pain and fever |
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| CA1339256C (en) * | 1989-01-26 | 1997-08-12 | Wulf Droge | Treatment of diseases associated with hiv-infections |
| IT1248995B (it) * | 1990-06-26 | 1995-02-11 | Italfarmaco Spa | Composizioni farmaceutiche a base di sali ferrosi |
| US5474757A (en) * | 1992-10-16 | 1995-12-12 | Rutgers University | Prevention of acetaminophen overdose toxicity with organosulfur compounds |
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- 2002-03-28 RU RU2003131876/15A patent/RU2291689C2/ru not_active IP Right Cessation
- 2002-03-28 AU AU2002255942A patent/AU2002255942B2/en not_active Expired
- 2002-03-28 EP EP02725376.4A patent/EP1379232B1/en not_active Revoked
- 2002-03-28 MX MXPA03008904A patent/MXPA03008904A/es active IP Right Grant
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- 2002-03-28 NZ NZ528478A patent/NZ528478A/en not_active IP Right Cessation
- 2002-03-28 WO PCT/US2002/009442 patent/WO2002078627A2/en not_active Ceased
- 2002-03-28 IL IL15818102A patent/IL158181A0/xx unknown
- 2002-03-28 JP JP2002576895A patent/JP2005508840A/ja active Pending
- 2002-03-28 BR BRPI0208563-1A patent/BR0208563A/pt not_active IP Right Cessation
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| WO2013006658A1 (en) * | 2011-07-05 | 2013-01-10 | The Brigham And Women's Hospital, Inc. | Treatment of acetaminophen-induced liver damage by the administration of modulators of nitric oxide |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1379232B1 (en) | 2015-07-29 |
| MXPA03008904A (es) | 2005-03-07 |
| EP1379232A4 (en) | 2008-04-23 |
| BR0208563A (pt) | 2006-02-21 |
| US20030069311A1 (en) | 2003-04-10 |
| IL158181A0 (en) | 2004-03-28 |
| CA2442168C (en) | 2012-05-29 |
| JP2005508840A (ja) | 2005-04-07 |
| JP2015078185A (ja) | 2015-04-23 |
| ES2550094T3 (es) | 2015-11-04 |
| CA2442168A1 (en) | 2002-10-10 |
| US20020142991A1 (en) | 2002-10-03 |
| WO2002078627A3 (en) | 2003-09-18 |
| AU2002255942B2 (en) | 2007-07-05 |
| RU2003131876A (ru) | 2005-04-10 |
| WO2002078627A2 (en) | 2002-10-10 |
| EP1379232A2 (en) | 2004-01-14 |
| IL158181A (en) | 2012-04-30 |
| CN100464743C (zh) | 2009-03-04 |
| CN1507350A (zh) | 2004-06-23 |
| JP2011225610A (ja) | 2011-11-10 |
| US7723389B2 (en) | 2010-05-25 |
| US6566401B2 (en) | 2003-05-20 |
| NZ528478A (en) | 2007-08-31 |
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