RU2265438C2 - Применение фульвестранта при лечении резистентного рака молочной железы - Google Patents
Применение фульвестранта при лечении резистентного рака молочной железы Download PDFInfo
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- RU2265438C2 RU2265438C2 RU2002129355/14A RU2002129355A RU2265438C2 RU 2265438 C2 RU2265438 C2 RU 2265438C2 RU 2002129355/14 A RU2002129355/14 A RU 2002129355/14A RU 2002129355 A RU2002129355 A RU 2002129355A RU 2265438 C2 RU2265438 C2 RU 2265438C2
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- A61K31/00—Medicinal preparations containing organic active ingredients
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- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| GB0008172.9 | 2000-04-05 |
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| RU2002129355A RU2002129355A (ru) | 2004-04-20 |
| RU2265438C2 true RU2265438C2 (ru) | 2005-12-10 |
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| RU2002129355/14A RU2265438C2 (ru) | 2000-04-05 | 2001-04-02 | Применение фульвестранта при лечении резистентного рака молочной железы |
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| IL159576A0 (en) * | 2001-07-07 | 2004-06-01 | Astrazeneca Ab | Pharmaceutical formulation for the intramuscular administration of fulvestrant |
| EP1623713A1 (en) * | 2004-07-09 | 2006-02-08 | Proskelia SAS | Cominations of pure anti-estrogen with aromatase inhibitors |
| US8557863B2 (en) * | 2005-09-27 | 2013-10-15 | Robert Benson Aylor | Suppression and prevention of tumors |
| CA2628747C (en) * | 2005-11-22 | 2014-01-21 | Incyte Corporation | Combinations of hormone therapy agents and metalloprotease inhibitors for the treatment of cancer |
| US7910108B2 (en) * | 2006-06-05 | 2011-03-22 | Incyte Corporation | Sheddase inhibitors combined with CD30-binding immunotherapeutics for the treatment of CD30 positive diseases |
| CA2835203A1 (en) * | 2011-05-09 | 2012-11-15 | University Of Virginia Patent Foundation | Compositions and methods for treating cancer |
| US9029582B2 (en) | 2011-05-20 | 2015-05-12 | Capital, Business Y Gestion De Finanzas S.L. | Pharmaceutical composition |
| US20160375234A1 (en) * | 2014-01-10 | 2016-12-29 | Atossa Genetic Inc. | Transpapillary methods and compositions for diagnosing and treating breast conditions |
| US9421264B2 (en) * | 2014-03-28 | 2016-08-23 | Duke University | Method of treating cancer using selective estrogen receptor modulators |
| CN116832020A (zh) | 2017-09-11 | 2023-10-03 | 阿托萨治疗学公司 | 制备和使用内昔芬的方法 |
| US20210253626A1 (en) * | 2018-05-24 | 2021-08-19 | Kashiv Biosciences, Llc | Prodrugs of fulvestrant |
| JP7662204B2 (ja) | 2019-07-03 | 2025-04-15 | アトッサ・セラピューティクス・インコーポレイテッド | エンドキシフェンの徐放性組成物 |
| CA3210276A1 (en) * | 2020-02-29 | 2021-09-02 | Frances E. Carr | Use of thyromimetics for the treatment of cancer |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999063974A2 (en) * | 1998-06-11 | 1999-12-16 | Endorecherche, Inc. | Selective estrogen receptor modulator in combination with denydroepiandrosterone (dhea) or analogues |
| WO1999063944A2 (en) * | 1998-06-08 | 1999-12-16 | Advanced Medicine, Inc. | Novel therapeutic agents that modulate estrogen receptors |
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2001
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- 2001-04-02 EE EEP200200574A patent/EE05026B1/xx unknown
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- 2001-04-02 CZ CZ20023309A patent/CZ303096B6/cs not_active IP Right Cessation
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- 2001-04-02 MX MXPA02009744A patent/MXPA02009744A/es active IP Right Grant
- 2001-04-02 US US10/240,656 patent/US20030158166A1/en not_active Abandoned
- 2001-04-02 HU HU0300339A patent/HU230064B1/hu unknown
- 2001-04-02 AU AU2001244372A patent/AU2001244372B2/en not_active Expired
- 2001-04-02 EP EP01917289A patent/EP1272195B1/en not_active Expired - Lifetime
- 2001-04-02 KR KR1020027013366A patent/KR100757764B1/ko not_active Expired - Lifetime
- 2001-04-02 PL PL357936A patent/PL201175B1/pl unknown
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- 2001-04-02 SK SK1429-2002A patent/SK287779B6/sk not_active IP Right Cessation
- 2001-04-02 CH CH01917289T patent/CH1272195H1/de unknown
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- 2001-04-02 DK DK01917289T patent/DK1272195T3/da active
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- 2001-04-02 CA CA002403608A patent/CA2403608A1/en not_active Abandoned
- 2001-04-02 BR BR0109789-0A patent/BR0109789A/pt not_active Application Discontinuation
- 2001-04-02 ES ES01917289T patent/ES2248300T3/es not_active Expired - Lifetime
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- 2001-04-02 DE DE60113975T patent/DE60113975T2/de not_active Expired - Lifetime
- 2001-04-02 EP EP05007561A patent/EP1586323A1/en not_active Withdrawn
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2002
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- 2002-10-02 NO NO20024735A patent/NO329949B1/no not_active IP Right Cessation
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999063944A2 (en) * | 1998-06-08 | 1999-12-16 | Advanced Medicine, Inc. | Novel therapeutic agents that modulate estrogen receptors |
| WO1999063974A2 (en) * | 1998-06-11 | 1999-12-16 | Endorecherche, Inc. | Selective estrogen receptor modulator in combination with denydroepiandrosterone (dhea) or analogues |
Non-Patent Citations (3)
| Title |
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| Lu Q. et al. The effects of aromatase inhibitors and antiestrogens in the nude mouse model. Breast Cancer Res. Treat. 1998 Jul;50(l):63-71, abstract. PubMed. * |
| весь документ. Long B.J. et al. The steroidal antiestrogen ICI 182, 780 is an inhibitor of cellular aromatase activity. J. Steroi. Biochem. Mol. Biol. 1998 Nov; 67(4):293-304, abstract, PubMed. Howell A. et al. Response to a specific antiesrogen (ICI 182780) in tamoxifen-resistant breast cancer. Lancet. 1995 Jan. 7; 345(8941):29-30, abstract. PubMed. Howell A. et al. Pharmacokinetics, pharmacological and anti-tumour effects of the specific anti-oestrogen ICI 182780 in women with advanced breast cancer. Br. J. Cancer.1996 Jul;74(2):300-8, abstract. PubMed. Brodie A. et al. Aromatase inhibitors and their antitumor effects in model systems. Endocr. Relat. Cancer. 1999 Jun;6(2):205-10, abstract. PubMed. * |
| с.1, 5-7, 10. * |
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