RU2264217C2 - Синергические способы и композиции для лечения рака - Google Patents
Синергические способы и композиции для лечения рака Download PDFInfo
- Publication number
- RU2264217C2 RU2264217C2 RU2002129000/14A RU2002129000A RU2264217C2 RU 2264217 C2 RU2264217 C2 RU 2264217C2 RU 2002129000/14 A RU2002129000/14 A RU 2002129000/14A RU 2002129000 A RU2002129000 A RU 2002129000A RU 2264217 C2 RU2264217 C2 RU 2264217C2
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- Russia
- Prior art keywords
- compound
- formula
- optionally substituted
- cells
- ylmethyl
- Prior art date
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- 0 C[C@@](C[C@@]1*c2ccccc2)[C@](CO)C(C[C@@]2(*)[C@](C)C([C@]3*)=C(C)[C@@](*)C2)C1(C)C3=O Chemical compound C[C@@](C[C@@]1*c2ccccc2)[C@](CO)C(C[C@@]2(*)[C@](C)C([C@]3*)=C(C)[C@@](*)C2)C1(C)C3=O 0.000 description 2
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19227800P | 2000-03-27 | 2000-03-27 | |
| US60/192,278 | 2000-03-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2002129000A RU2002129000A (ru) | 2004-03-27 |
| RU2264217C2 true RU2264217C2 (ru) | 2005-11-20 |
Family
ID=22709017
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2002129000/14A RU2264217C2 (ru) | 2000-03-27 | 2001-03-22 | Синергические способы и композиции для лечения рака |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US6537988B2 (enExample) |
| EP (1) | EP1272193B1 (enExample) |
| JP (1) | JP5110756B2 (enExample) |
| KR (1) | KR20020084254A (enExample) |
| CN (1) | CN100384424C (enExample) |
| AR (1) | AR028296A1 (enExample) |
| AT (1) | ATE430570T1 (enExample) |
| AU (2) | AU2001247683B2 (enExample) |
| BR (1) | BR0109517A (enExample) |
| CA (1) | CA2404712A1 (enExample) |
| CZ (1) | CZ20023220A3 (enExample) |
| DE (1) | DE60138611D1 (enExample) |
| ES (1) | ES2325055T3 (enExample) |
| HU (1) | HUP0301690A3 (enExample) |
| IL (1) | IL151373A0 (enExample) |
| MX (1) | MXPA02009463A (enExample) |
| MY (1) | MY127082A (enExample) |
| NO (1) | NO20024610L (enExample) |
| PE (1) | PE20011291A1 (enExample) |
| RU (1) | RU2264217C2 (enExample) |
| TW (1) | TWI310684B (enExample) |
| UY (1) | UY26635A1 (enExample) |
| WO (1) | WO2001072721A2 (enExample) |
| ZA (1) | ZA200207766B (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2325914C2 (ru) * | 2006-06-15 | 2008-06-10 | Государственное учреждение научно-исследовательский институт онкологии Томского Научного центра Сибирского отделения Российской академии медицинских наук (ГУ НИИ онкологии ТНЦ СО РАМН) | Способ лечения операбельного рака молочной железы |
| RU2365370C1 (ru) * | 2008-04-29 | 2009-08-27 | Государственное учреждение Российский онкологический научный центр им. Н.Н. Блохина РАМН | Способ лечения рака легкого |
| RU2492860C2 (ru) * | 2008-06-17 | 2013-09-20 | УАЙТ ЭлЭлСи | Антиопластические комбинации, содержащие нкi-272 и винорелбин |
| RU2532375C2 (ru) * | 2008-11-28 | 2014-11-10 | Новартис Аг | ФАРМАЦЕВТИЧЕСКИЕ КОМБИНАЦИИ, ВКЛЮЧАЮЩИЕ ПРОИЗВОДНЫЕ ПИРИДО [4,3-d]ПИРИМИДИНА В КАЧЕСТВЕ ИНГИБИТОРА HSP90 И ИНГИБИТОРА HER2 |
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| JP4579351B2 (ja) * | 1996-12-03 | 2010-11-10 | スローン−ケッタリング インスティトュート フォア キャンサー リサーチ | エポチロンの合成とその中間体及びその類似物並びにその使用 |
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| US20050043376A1 (en) * | 1996-12-03 | 2005-02-24 | Danishefsky Samuel J. | Synthesis of epothilones, intermediates thereto, analogues and uses thereof |
| US20020058286A1 (en) * | 1999-02-24 | 2002-05-16 | Danishefsky Samuel J. | Synthesis of epothilones, intermediates thereto and analogues thereof |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2325914C2 (ru) * | 2006-06-15 | 2008-06-10 | Государственное учреждение научно-исследовательский институт онкологии Томского Научного центра Сибирского отделения Российской академии медицинских наук (ГУ НИИ онкологии ТНЦ СО РАМН) | Способ лечения операбельного рака молочной железы |
| RU2365370C1 (ru) * | 2008-04-29 | 2009-08-27 | Государственное учреждение Российский онкологический научный центр им. Н.Н. Блохина РАМН | Способ лечения рака легкого |
| RU2492860C2 (ru) * | 2008-06-17 | 2013-09-20 | УАЙТ ЭлЭлСи | Антиопластические комбинации, содержащие нкi-272 и винорелбин |
| RU2532375C2 (ru) * | 2008-11-28 | 2014-11-10 | Новартис Аг | ФАРМАЦЕВТИЧЕСКИЕ КОМБИНАЦИИ, ВКЛЮЧАЮЩИЕ ПРОИЗВОДНЫЕ ПИРИДО [4,3-d]ПИРИМИДИНА В КАЧЕСТВЕ ИНГИБИТОРА HSP90 И ИНГИБИТОРА HER2 |
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| HUP0301690A3 (en) | 2005-05-30 |
| BR0109517A (pt) | 2006-08-29 |
| US6537988B2 (en) | 2003-03-25 |
| UY26635A1 (es) | 2001-10-25 |
| KR20020084254A (ko) | 2002-11-04 |
| WO2001072721A3 (en) | 2002-06-13 |
| NO20024610D0 (no) | 2002-09-26 |
| EP1272193B1 (en) | 2009-05-06 |
| RU2002129000A (ru) | 2004-03-27 |
| EP1272193A2 (en) | 2003-01-08 |
| DE60138611D1 (de) | 2009-06-18 |
| AU4768301A (en) | 2001-10-08 |
| JP2003528864A (ja) | 2003-09-30 |
| AR028296A1 (es) | 2003-04-30 |
| CA2404712A1 (en) | 2001-10-04 |
| IL151373A0 (en) | 2003-04-10 |
| CN1419452A (zh) | 2003-05-21 |
| ATE430570T1 (de) | 2009-05-15 |
| CZ20023220A3 (cs) | 2003-11-12 |
| ZA200207766B (en) | 2003-01-20 |
| CN100384424C (zh) | 2008-04-30 |
| HUP0301690A2 (hu) | 2003-08-28 |
| NO20024610L (no) | 2002-11-25 |
| ES2325055T3 (es) | 2009-08-25 |
| JP5110756B2 (ja) | 2012-12-26 |
| MXPA02009463A (es) | 2003-04-10 |
| US20020002162A1 (en) | 2002-01-03 |
| MY127082A (en) | 2006-11-30 |
| WO2001072721A2 (en) | 2001-10-04 |
| PE20011291A1 (es) | 2002-01-13 |
| TWI310684B (en) | 2009-06-11 |
| AU2001247683B2 (en) | 2006-01-12 |
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