BR0109517A - métodos e composições sinérgicas para tratar o cáncer - Google Patents
métodos e composições sinérgicas para tratar o cáncerInfo
- Publication number
- BR0109517A BR0109517A BRPI0109517-0A BR0109517A BR0109517A BR 0109517 A BR0109517 A BR 0109517A BR 0109517 A BR0109517 A BR 0109517A BR 0109517 A BR0109517 A BR 0109517A
- Authority
- BR
- Brazil
- Prior art keywords
- cancer
- compositions
- agents
- synergistic
- treating cancer
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 4
- 201000011510 cancer Diseases 0.000 title abstract 4
- 230000002195 synergetic effect Effects 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 230000001028 anti-proliverative effect Effects 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000000824 cytostatic agent Substances 0.000 abstract 2
- 239000002254 cytotoxic agent Substances 0.000 abstract 2
- 229940127089 cytotoxic agent Drugs 0.000 abstract 2
- 231100000599 cytotoxic agent Toxicity 0.000 abstract 2
- 230000001085 cytostatic effect Effects 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
- A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0038—Radiosensitizing, i.e. administration of pharmaceutical agents that enhance the effect of radiotherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19227800P | 2000-03-27 | 2000-03-27 | |
| PCT/US2001/009193 WO2001072721A2 (en) | 2000-03-27 | 2001-03-22 | Synergistic methods and compositions for treating cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0109517A true BR0109517A (pt) | 2006-08-29 |
Family
ID=22709017
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0109517-0A BR0109517A (pt) | 2000-03-27 | 2001-03-22 | métodos e composições sinérgicas para tratar o cáncer |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US6537988B2 (enExample) |
| EP (1) | EP1272193B1 (enExample) |
| JP (1) | JP5110756B2 (enExample) |
| KR (1) | KR20020084254A (enExample) |
| CN (1) | CN100384424C (enExample) |
| AR (1) | AR028296A1 (enExample) |
| AT (1) | ATE430570T1 (enExample) |
| AU (2) | AU2001247683B2 (enExample) |
| BR (1) | BR0109517A (enExample) |
| CA (1) | CA2404712A1 (enExample) |
| CZ (1) | CZ20023220A3 (enExample) |
| DE (1) | DE60138611D1 (enExample) |
| ES (1) | ES2325055T3 (enExample) |
| HU (1) | HUP0301690A3 (enExample) |
| IL (1) | IL151373A0 (enExample) |
| MX (1) | MXPA02009463A (enExample) |
| MY (1) | MY127082A (enExample) |
| NO (1) | NO20024610L (enExample) |
| PE (1) | PE20011291A1 (enExample) |
| RU (1) | RU2264217C2 (enExample) |
| TW (1) | TWI310684B (enExample) |
| UY (1) | UY26635A1 (enExample) |
| WO (1) | WO2001072721A2 (enExample) |
| ZA (1) | ZA200207766B (enExample) |
Families Citing this family (108)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1998022461A1 (de) * | 1996-11-18 | 1998-05-28 | GESELLSCHAFT FüR BIOTECHNOLOGISCHE FORSCHUNG MBH (GBF) | Epothilone c, d, e und f, deren herstellung und deren verwendung als cytostatische mittel bzw. als pflanzenschutzmittel |
| JP4579351B2 (ja) * | 1996-12-03 | 2010-11-10 | スローン−ケッタリング インスティトュート フォア キャンサー リサーチ | エポチロンの合成とその中間体及びその類似物並びにその使用 |
| US6204388B1 (en) | 1996-12-03 | 2001-03-20 | Sloan-Kettering Institute For Cancer Research | Synthesis of epothilones, intermediates thereto and analogues thereof |
| US6867305B2 (en) * | 1996-12-03 | 2005-03-15 | Sloan-Kettering Institute For Cancer Research | Synthesis of epothilones, intermediates thereto and analogues thereof |
| US20050043376A1 (en) * | 1996-12-03 | 2005-02-24 | Danishefsky Samuel J. | Synthesis of epothilones, intermediates thereto, analogues and uses thereof |
| US20020058286A1 (en) * | 1999-02-24 | 2002-05-16 | Danishefsky Samuel J. | Synthesis of epothilones, intermediates thereto and analogues thereof |
| AU2002211427A1 (en) * | 2000-10-05 | 2002-04-15 | Whitehead Institute For Biomedical Research | Effects of combined administration of farnesyl transferase inhibitors and signal transduction inhibitors |
| AU2002214649A1 (en) * | 2000-10-16 | 2002-04-29 | Neopharm, Inc. | Liposomal formulation of mitoxantrone |
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| US6921769B2 (en) | 2002-08-23 | 2005-07-26 | Sloan-Kettering Institute For Cancer Research | Synthesis of epothilones, intermediates thereto and analogues thereof |
| CA2496477C (en) * | 2002-08-23 | 2012-10-16 | Sloan-Kettering Institute For Cancer Research | Synthesis of epothilones, intermediates thereto, analogues and uses thereof |
| US7649006B2 (en) * | 2002-08-23 | 2010-01-19 | Sloan-Kettering Institute For Cancer Research | Synthesis of epothilones, intermediates thereto and analogues thereof |
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| US8613922B2 (en) | 2003-04-24 | 2013-12-24 | The University Of North Carolina At Chapel Hill | Methods for inhibiting diabetic retinopathy with an antibody against integrin associated protein (IAP) |
| US20050043233A1 (en) | 2003-04-29 | 2005-02-24 | Boehringer Ingelheim International Gmbh | Combinations for the treatment of diseases involving cell proliferation, migration or apoptosis of myeloma cells or angiogenesis |
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| JP2014519813A (ja) | 2011-04-25 | 2014-08-21 | オーエスアイ・ファーマシューティカルズ,エルエルシー | 癌薬剤発見、診断、および治療におけるemt遺伝子シグネチャーの使用 |
| WO2013152252A1 (en) | 2012-04-06 | 2013-10-10 | OSI Pharmaceuticals, LLC | Combination anti-cancer therapy |
| CN103374000B (zh) * | 2012-04-13 | 2015-11-11 | 中国科学院广州生物医药与健康研究院 | 嘧啶并二氮杂卓类化合物及其药用组合物和应用 |
| SG10201912985RA (en) | 2013-07-12 | 2020-02-27 | Ophthotech Corp | Methods for treating or preventing ophthalmological conditions |
| CN107043456B (zh) * | 2017-04-19 | 2019-05-17 | 川北医学院 | 对氧环己酮与l-苯丙氨酸氮芥共聚物及其应用 |
| CA3068256A1 (en) | 2017-06-21 | 2018-12-27 | The University Of North Carolina At Chapel Hill | Methods and compositions for chimeric antigen receptor targeting cancer cells |
| CA3103130A1 (en) | 2018-06-13 | 2019-12-19 | The University Of North Carolina At Chapel Hill | Methods and compositions for chimeric antigen receptor targeting cancer cells |
| US11068254B1 (en) | 2020-06-10 | 2021-07-20 | Cigna Intellectual Property, Inc. | Systems and methods for generating and managing domain-based technology architecture |
| WO2022256656A1 (en) * | 2021-06-03 | 2022-12-08 | University Of Cincinnati | Bzd-1 as a chemosensitizer of cancer |
| CN120695174A (zh) * | 2021-07-01 | 2025-09-26 | 江苏先声生物制药有限公司 | 抗人vegf抗体与化药联用在制备治疗卵巢癌的药物中的应用 |
| US11879010B2 (en) | 2021-09-30 | 2024-01-23 | The Charlotte Mecklenburg Hospital Authority | Methods and compositions for pretargeted immunotherapy |
| CN114712377B (zh) * | 2022-04-26 | 2023-08-15 | 江苏师范大学 | 断血流皂苷a在制造药物中的用途 |
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| US6011029A (en) * | 1996-02-26 | 2000-01-04 | Bristol-Myers Squibb Company | Inhibitors of farnesyl protein transferase |
| DE19706584C2 (de) * | 1997-02-21 | 2002-09-26 | Aeg Energietechnik Gmbh | Hochtemperaturbrennstoffzellen mit Erwärmung des Reaktionsgases |
| GB9801231D0 (en) | 1997-06-05 | 1998-03-18 | Merck & Co Inc | A method of treating cancer |
| WO1999002573A1 (en) * | 1997-07-08 | 1999-01-21 | Union Carbide Chemicals & Plastics Technology Cor Poration | Method for reducing sheeting during olefin polymerization |
| CZ298511B6 (cs) | 1997-12-22 | 2007-10-24 | Schering Corporation | Použití benzocykloheptapyridinových sloucenin proprípravu farmaceutického prípravku pro použití v kombinaci s antineoplastickým lécivem a/nebo radioterapií k lécení proliferacních onemocnení |
| TR200102109T2 (tr) * | 1999-01-21 | 2001-12-21 | Bristol-Myers Squibb Company | Ras-farnesiltransferazı inhibitörü ve sülfobütileter-7-ß-siklodekstrin veya 2-hidroksipropil-ß-siklodekstrin kompleksi ve metod. |
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2001
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- 2001-03-22 CZ CZ20023220A patent/CZ20023220A3/cs unknown
- 2001-03-22 AU AU2001247683A patent/AU2001247683B2/en not_active Ceased
- 2001-03-22 ES ES01920653T patent/ES2325055T3/es not_active Expired - Lifetime
- 2001-03-22 MY MYPI20011361A patent/MY127082A/en unknown
- 2001-03-22 EP EP01920653A patent/EP1272193B1/en not_active Expired - Lifetime
- 2001-03-22 MX MXPA02009463A patent/MXPA02009463A/es active IP Right Grant
- 2001-03-22 KR KR1020027012704A patent/KR20020084254A/ko not_active Withdrawn
- 2001-03-22 HU HU0301690A patent/HUP0301690A3/hu unknown
- 2001-03-22 RU RU2002129000/14A patent/RU2264217C2/ru not_active IP Right Cessation
- 2001-03-22 JP JP2001570634A patent/JP5110756B2/ja not_active Expired - Fee Related
- 2001-03-22 BR BRPI0109517-0A patent/BR0109517A/pt not_active Application Discontinuation
- 2001-03-22 AU AU4768301A patent/AU4768301A/xx active Pending
- 2001-03-22 IL IL15137301A patent/IL151373A0/xx not_active IP Right Cessation
- 2001-03-22 AT AT01920653T patent/ATE430570T1/de not_active IP Right Cessation
- 2001-03-22 DE DE60138611T patent/DE60138611D1/de not_active Expired - Lifetime
- 2001-03-22 CN CNB018071627A patent/CN100384424C/zh not_active Expired - Fee Related
- 2001-03-22 CA CA002404712A patent/CA2404712A1/en not_active Abandoned
- 2001-03-22 WO PCT/US2001/009193 patent/WO2001072721A2/en not_active Ceased
- 2001-03-26 US US09/817,456 patent/US6537988B2/en not_active Expired - Fee Related
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- 2001-03-27 AR ARP010101457A patent/AR028296A1/es unknown
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2002
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| US6537988B2 (en) | 2003-03-25 |
| UY26635A1 (es) | 2001-10-25 |
| KR20020084254A (ko) | 2002-11-04 |
| RU2264217C2 (ru) | 2005-11-20 |
| WO2001072721A3 (en) | 2002-06-13 |
| NO20024610D0 (no) | 2002-09-26 |
| EP1272193B1 (en) | 2009-05-06 |
| RU2002129000A (ru) | 2004-03-27 |
| EP1272193A2 (en) | 2003-01-08 |
| DE60138611D1 (de) | 2009-06-18 |
| AU4768301A (en) | 2001-10-08 |
| JP2003528864A (ja) | 2003-09-30 |
| AR028296A1 (es) | 2003-04-30 |
| CA2404712A1 (en) | 2001-10-04 |
| IL151373A0 (en) | 2003-04-10 |
| CN1419452A (zh) | 2003-05-21 |
| ATE430570T1 (de) | 2009-05-15 |
| CZ20023220A3 (cs) | 2003-11-12 |
| ZA200207766B (en) | 2003-01-20 |
| CN100384424C (zh) | 2008-04-30 |
| HUP0301690A2 (hu) | 2003-08-28 |
| NO20024610L (no) | 2002-11-25 |
| ES2325055T3 (es) | 2009-08-25 |
| JP5110756B2 (ja) | 2012-12-26 |
| MXPA02009463A (es) | 2003-04-10 |
| US20020002162A1 (en) | 2002-01-03 |
| MY127082A (en) | 2006-11-30 |
| WO2001072721A2 (en) | 2001-10-04 |
| PE20011291A1 (es) | 2002-01-13 |
| TWI310684B (en) | 2009-06-11 |
| AU2001247683B2 (en) | 2006-01-12 |
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