RU2250768C2 - Фармацевтическая композиция и способ лечения прогрессирующего фиброза и цирроза печени - Google Patents

Фармацевтическая композиция и способ лечения прогрессирующего фиброза и цирроза печени Download PDF

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Publication number
RU2250768C2
RU2250768C2 RU2002126216/15A RU2002126216A RU2250768C2 RU 2250768 C2 RU2250768 C2 RU 2250768C2 RU 2002126216/15 A RU2002126216/15 A RU 2002126216/15A RU 2002126216 A RU2002126216 A RU 2002126216A RU 2250768 C2 RU2250768 C2 RU 2250768C2
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RU
Russia
Prior art keywords
oltipraz
ddb
liver
dmn
fibrosis
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RU2002126216/15A
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English (en)
Russian (ru)
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RU2002126216A (ru
Inventor
Санг Геон КИМ (KR)
Санг Геон КИМ
Кеон Вук КАНГ (KR)
Кеон Вук КАНГ
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Санг Геон КИМ
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Application filed by Санг Геон КИМ filed Critical Санг Геон КИМ
Publication of RU2002126216A publication Critical patent/RU2002126216A/ru
Application granted granted Critical
Publication of RU2250768C2 publication Critical patent/RU2250768C2/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RU2002126216/15A 2000-03-02 2001-03-02 Фармацевтическая композиция и способ лечения прогрессирующего фиброза и цирроза печени RU2250768C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20000010540 2000-03-02
KR2000/10540 2000-03-02
KR2000110540 2000-03-02

Publications (2)

Publication Number Publication Date
RU2002126216A RU2002126216A (ru) 2004-03-20
RU2250768C2 true RU2250768C2 (ru) 2005-04-27

Family

ID=36776473

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2002126216/15A RU2250768C2 (ru) 2000-03-02 2001-03-02 Фармацевтическая композиция и способ лечения прогрессирующего фиброза и цирроза печени

Country Status (10)

Country Link
EP (1) EP1263435B1 (cg-RX-API-DMAC10.html)
JP (1) JP4226246B2 (cg-RX-API-DMAC10.html)
CN (1) CN1218698C (cg-RX-API-DMAC10.html)
AT (1) ATE332693T1 (cg-RX-API-DMAC10.html)
AU (1) AU2001237768A1 (cg-RX-API-DMAC10.html)
BR (1) BR0108732A (cg-RX-API-DMAC10.html)
DE (1) DE60121426T2 (cg-RX-API-DMAC10.html)
ES (1) ES2267722T3 (cg-RX-API-DMAC10.html)
RU (1) RU2250768C2 (cg-RX-API-DMAC10.html)
WO (1) WO2001064215A1 (cg-RX-API-DMAC10.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2427372C2 (ru) * 2005-06-17 2011-08-27 Новартис Аг Применение санглиферина для лечения вируса гепатита с

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030067935A (ko) * 2002-02-09 2003-08-19 김상건 올티프라즈를 포함하는 간경화(간경변증) 치료를 위한 간 조직 재생용 제약 조성물
KR100629771B1 (ko) * 2004-01-27 2006-09-28 씨제이 주식회사 결정성이 감소되거나 무정형화된 올티프라즈의 제조방법
KR100604261B1 (ko) 2004-10-11 2006-07-28 재단법인서울대학교산학협력재단 신규4,5,6,7-테트라히드로-[1,2]디티올로[4,3-c]피리딘-3-티온계 화합물
WO2007131973A2 (en) * 2006-05-11 2007-11-22 Prendergast Patrick T Compositions and methods for modulating the immune system

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998027970A2 (en) * 1996-12-24 1998-07-02 National Research Council Of Canada Treatment of diseases or prevention of cellular damage caused by oxygen-containing free radicals
US5786344A (en) * 1994-07-05 1998-07-28 Arch Development Corporation Camptothecin drug combinations and methods with reduced side effects

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5786344A (en) * 1994-07-05 1998-07-28 Arch Development Corporation Camptothecin drug combinations and methods with reduced side effects
WO1998027970A2 (en) * 1996-12-24 1998-07-02 National Research Council Of Canada Treatment of diseases or prevention of cellular damage caused by oxygen-containing free radicals

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2427372C2 (ru) * 2005-06-17 2011-08-27 Новартис Аг Применение санглиферина для лечения вируса гепатита с

Also Published As

Publication number Publication date
DE60121426D1 (de) 2006-08-24
EP1263435A1 (en) 2002-12-11
BR0108732A (pt) 2002-12-17
JP2004538239A (ja) 2004-12-24
CN1218698C (zh) 2005-09-14
ATE332693T1 (de) 2006-08-15
DE60121426T2 (de) 2007-02-22
EP1263435B1 (en) 2006-07-12
ES2267722T3 (es) 2007-03-16
AU2001237768A1 (en) 2001-09-12
JP4226246B2 (ja) 2009-02-18
EP1263435A4 (en) 2004-08-11
WO2001064215A1 (en) 2001-09-07
RU2002126216A (ru) 2004-03-20
CN1407891A (zh) 2003-04-02

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Effective date: 20060504

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Effective date: 20150303