RU2166330C2 - Комбинация, содержащая антагонист рецептора ангиотензина ii и эпоксистероидный антагонист рецептора альдостерона - Google Patents

Комбинация, содержащая антагонист рецептора ангиотензина ii и эпоксистероидный антагонист рецептора альдостерона Download PDF

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Publication number
RU2166330C2
RU2166330C2 RU98100250/14A RU98100250A RU2166330C2 RU 2166330 C2 RU2166330 C2 RU 2166330C2 RU 98100250/14 A RU98100250/14 A RU 98100250/14A RU 98100250 A RU98100250 A RU 98100250A RU 2166330 C2 RU2166330 C2 RU 2166330C2
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Russia
Prior art keywords
epoxy
antagonist
angiotensin
hydroxy
receptor antagonist
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RU98100250/14A
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English (en)
Russian (ru)
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RU98100250A (ru
Inventor
С. АЛЕКСАНДЕР Джон
Р. ШУХ Джозеф
Дж. Горжински Ричард
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Джи. Ди. Сирл Энд Ко.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
RU98100250/14A 1995-06-07 1996-06-05 Комбинация, содержащая антагонист рецептора ангиотензина ii и эпоксистероидный антагонист рецептора альдостерона RU2166330C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48645695A 1995-06-07 1995-06-07
US08/486,456 1995-06-07

Publications (2)

Publication Number Publication Date
RU98100250A RU98100250A (ru) 1999-09-27
RU2166330C2 true RU2166330C2 (ru) 2001-05-10

Family

ID=23931955

Family Applications (1)

Application Number Title Priority Date Filing Date
RU98100250/14A RU2166330C2 (ru) 1995-06-07 1996-06-05 Комбинация, содержащая антагонист рецептора ангиотензина ii и эпоксистероидный антагонист рецептора альдостерона

Country Status (21)

Country Link
US (1) US6653306B1 (enExample)
EP (1) EP0831910B1 (enExample)
JP (1) JPH11507627A (enExample)
KR (1) KR100618466B1 (enExample)
CN (2) CN1142793C (enExample)
AT (1) ATE209047T1 (enExample)
AU (1) AU725689B2 (enExample)
BR (1) BR9609066A (enExample)
CA (1) CA2224079A1 (enExample)
CZ (1) CZ297975B6 (enExample)
DE (1) DE69617235T2 (enExample)
DK (1) DK0831910T3 (enExample)
ES (1) ES2167571T3 (enExample)
IL (1) IL122242A (enExample)
NO (1) NO318184B1 (enExample)
NZ (1) NZ310730A (enExample)
PL (1) PL185150B1 (enExample)
PT (1) PT831910E (enExample)
RO (1) RO118046B1 (enExample)
RU (1) RU2166330C2 (enExample)
WO (1) WO1996040257A1 (enExample)

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RU2336876C2 (ru) * 2002-05-29 2008-10-27 Новартис Аг Комбинация ингибитора дипептидилпептидазы iv (dpp iv) и сердечно-сосудистого вещества

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US6306826B1 (en) 1997-06-04 2001-10-23 The Regents Of The University Of California Treatment of heart failure with growth hormone
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Publication number Priority date Publication date Assignee Title
RU2336876C2 (ru) * 2002-05-29 2008-10-27 Новартис Аг Комбинация ингибитора дипептидилпептидазы iv (dpp iv) и сердечно-сосудистого вещества

Also Published As

Publication number Publication date
CN1522701A (zh) 2004-08-25
PT831910E (pt) 2002-05-31
CA2224079A1 (en) 1996-12-19
DK0831910T3 (da) 2002-05-21
AU725689B2 (en) 2000-10-19
DE69617235D1 (de) 2002-01-03
DE69617235T2 (de) 2002-07-25
BR9609066A (pt) 1999-01-26
NO318184B1 (no) 2005-02-14
NO975741D0 (no) 1997-12-05
CN1192697A (zh) 1998-09-09
WO1996040257A1 (en) 1996-12-19
EP0831910A1 (en) 1998-04-01
US6653306B1 (en) 2003-11-25
CZ385097A3 (cs) 1998-06-17
EP0831910B1 (en) 2001-11-21
IL122242A (en) 2001-07-24
RO118046B1 (ro) 2003-01-30
CN1142793C (zh) 2004-03-24
ES2167571T3 (es) 2002-05-16
KR19990022548A (ko) 1999-03-25
KR100618466B1 (ko) 2006-12-13
NO975741L (no) 1998-01-29
AU6157796A (en) 1996-12-30
PL324001A1 (en) 1998-04-27
PL185150B1 (pl) 2003-03-31
ATE209047T1 (de) 2001-12-15
NZ310730A (en) 2001-01-26
JPH11507627A (ja) 1999-07-06
IL122242A0 (en) 1998-04-05
CZ297975B6 (cs) 2007-05-09

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Effective date: 20090606