RU2161964C2 - Способ ингибирования (угнетения) эндометриального рака - Google Patents

Способ ингибирования (угнетения) эндометриального рака Download PDF

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Publication number
RU2161964C2
RU2161964C2 RU97104160/14A RU97104160A RU2161964C2 RU 2161964 C2 RU2161964 C2 RU 2161964C2 RU 97104160/14 A RU97104160/14 A RU 97104160/14A RU 97104160 A RU97104160 A RU 97104160A RU 2161964 C2 RU2161964 C2 RU 2161964C2
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RU
Russia
Prior art keywords
treatment
endometrial cancer
compound
endometrial
formula
Prior art date
Application number
RU97104160/14A
Other languages
English (en)
Russian (ru)
Other versions
RU97104160A (ru
Inventor
Маргарет БОСС Сюзн
Original Assignee
Эли Лилли Энд Компани
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эли Лилли Энд Компани filed Critical Эли Лилли Энд Компани
Publication of RU97104160A publication Critical patent/RU97104160A/ru
Application granted granted Critical
Publication of RU2161964C2 publication Critical patent/RU2161964C2/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
RU97104160/14A 1994-08-22 1995-08-21 Способ ингибирования (угнетения) эндометриального рака RU2161964C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29385394A 1994-08-22 1994-08-22
US08/293,853 1994-08-22

Publications (2)

Publication Number Publication Date
RU97104160A RU97104160A (ru) 1999-03-20
RU2161964C2 true RU2161964C2 (ru) 2001-01-20

Family

ID=23130867

Family Applications (1)

Application Number Title Priority Date Filing Date
RU97104160/14A RU2161964C2 (ru) 1994-08-22 1995-08-21 Способ ингибирования (угнетения) эндометриального рака

Country Status (17)

Country Link
EP (1) EP0777476A4 (no)
JP (1) JPH10504824A (no)
KR (1) KR970705387A (no)
AU (1) AU688112B2 (no)
CA (1) CA2198119A1 (no)
CZ (1) CZ51897A3 (no)
FI (1) FI970717A0 (no)
HU (1) HUT76890A (no)
IL (1) IL115022A (no)
MX (1) MX9701327A (no)
MY (1) MY113757A (no)
NO (1) NO970783D0 (no)
NZ (1) NZ292017A (no)
RU (1) RU2161964C2 (no)
TW (1) TW404834B (no)
WO (1) WO1996005833A1 (no)
ZA (1) ZA956994B (no)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2734390C2 (ru) * 2014-12-02 2020-10-15 Си энд Си РИСЕРЧ ЛЭБОРЕТРИЗ Гетероциклические производные и их применение

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5856340A (en) * 1995-02-28 1999-01-05 Eli Lilly And Company Method of treating estrogen dependent cancers
US6465445B1 (en) 1998-06-11 2002-10-15 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
US7005428B1 (en) 1998-06-11 2006-02-28 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
CN115825414B (zh) * 2023-01-09 2023-04-25 中国医学科学院北京协和医院 血液或尿液代谢标志物及其在子宫内膜癌早筛中的应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4418068A (en) * 1981-04-03 1983-11-29 Eli Lilly And Company Antiestrogenic and antiandrugenic benzothiophenes
JP3157882B2 (ja) * 1991-11-15 2001-04-16 帝国臓器製薬株式会社 新規なベンゾチオフエン誘導体
US5482949A (en) * 1993-03-19 1996-01-09 Eli Lilly And Company Sulfonate derivatives of 3-aroylbenzo[b]thiophenes
WO1994023068A1 (en) * 1993-04-07 1994-10-13 Ligand Pharmaceuticals, Incorporated Method for screening for receptor agonists
ATE220323T1 (de) * 1993-10-15 2002-07-15 Lilly Co Eli Methode zur behandlung von resistenten neoplasmen
WO1996005832A1 (en) * 1994-08-22 1996-02-29 Eli Lilly And Company Methods of inhibiting primary endometrial hyperplasia
US5843964A (en) * 1994-09-22 1998-12-01 Eli Lilly And Company Methods of inhibiting endometrial mitoses

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Машковский М.Д. Лекарственные средства. - М.: Медицина, 1986, ч.2, с.450. *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2734390C2 (ru) * 2014-12-02 2020-10-15 Си энд Си РИСЕРЧ ЛЭБОРЕТРИЗ Гетероциклические производные и их применение

Also Published As

Publication number Publication date
TW404834B (en) 2000-09-11
FI970717A (fi) 1997-02-20
NO970783L (no) 1997-02-20
IL115022A (en) 2000-07-31
FI970717A0 (fi) 1997-02-20
KR970705387A (ko) 1997-10-09
AU688112B2 (en) 1998-03-05
IL115022A0 (en) 1998-06-15
EP0777476A4 (en) 1999-06-23
ZA956994B (en) 1997-02-21
HUT76890A (en) 1997-12-29
CA2198119A1 (en) 1996-02-29
WO1996005833A1 (en) 1996-02-29
MX9701327A (es) 1997-05-31
JPH10504824A (ja) 1998-05-12
NZ292017A (en) 2000-07-28
NO970783D0 (no) 1997-02-20
CZ51897A3 (en) 1997-06-11
EP0777476A1 (en) 1997-06-11
AU3370095A (en) 1996-03-14
MY113757A (en) 2002-05-31

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