RU2114621C1 - Композиции и способ предупреждения зачатия - Google Patents

Композиции и способ предупреждения зачатия Download PDF

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Publication number
RU2114621C1
RU2114621C1 SU4742272A SU4742272A RU2114621C1 RU 2114621 C1 RU2114621 C1 RU 2114621C1 SU 4742272 A SU4742272 A SU 4742272A SU 4742272 A SU4742272 A SU 4742272A RU 2114621 C1 RU2114621 C1 RU 2114621C1
Authority
RU
Russia
Prior art keywords
melatonin
progestogen
daily
days
estrogen
Prior art date
Application number
SU4742272A
Other languages
English (en)
Russian (ru)
Inventor
Кохен Майкл
Original Assignee
Эпплайд Медикал Рисерч, Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эпплайд Медикал Рисерч, Лтд. filed Critical Эпплайд Медикал Рисерч, Лтд.
Application granted granted Critical
Publication of RU2114621C1 publication Critical patent/RU2114621C1/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Seeds, Soups, And Other Foods (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
SU4742272A 1987-03-23 1988-03-22 Композиции и способ предупреждения зачатия RU2114621C1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US029229 1987-03-23
US07/029,229 US4855305A (en) 1987-03-23 1987-03-23 Compositions and methods of effecting contraception utilizing melatonin
PCT/US1988/000971 WO1988007370A1 (en) 1987-03-23 1988-03-22 Compositions and methods of effecting contraception and control of breast cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
SU925052817A Division RU2067001C1 (ru) 1987-03-23 1988-03-22 Способ снижения риска заболевания раком молочной железы

Publications (1)

Publication Number Publication Date
RU2114621C1 true RU2114621C1 (ru) 1998-07-10

Family

ID=21847942

Family Applications (1)

Application Number Title Priority Date Filing Date
SU4742272A RU2114621C1 (ru) 1987-03-23 1988-03-22 Композиции и способ предупреждения зачатия

Country Status (26)

Country Link
US (1) US4855305A (enExample)
EP (1) EP0354921B1 (enExample)
JP (2) JP2965160B2 (enExample)
KR (1) KR890700349A (enExample)
CN (1) CN1041383C (enExample)
AT (1) ATE143807T1 (enExample)
AU (3) AU628784B2 (enExample)
BG (1) BG51075A1 (enExample)
BR (1) BR8807426A (enExample)
CA (1) CA1322527C (enExample)
DD (1) DD269557A5 (enExample)
DE (1) DE3855606T2 (enExample)
EG (1) EG18583A (enExample)
ES (1) ES2009251A6 (enExample)
FI (1) FI894423L (enExample)
GR (1) GR1002146B (enExample)
HU (1) HU208487B (enExample)
IL (1) IL85814A (enExample)
IN (1) IN166946B (enExample)
NZ (1) NZ223989A (enExample)
OA (1) OA09134A (enExample)
PH (1) PH26709A (enExample)
PT (1) PT87053B (enExample)
RU (1) RU2114621C1 (enExample)
WO (1) WO1988007370A1 (enExample)
ZA (1) ZA882079B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017003321A3 (ru) * 2015-07-01 2017-03-23 Общество с ограниченной ответственностью "Научно-внедренческий центр Агроветзащита" Способ регулирования полового поведения и контрацепции самок млекопитающих
RU2616252C2 (ru) * 2015-08-04 2017-04-13 Общество с ограниченной ответственностью "Научно-внедренческий центр Агроветзащита" Способ регулирования полового поведения самцов млекопитающих

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR1001395B (el) * 1987-03-23 1993-10-29 Michael Cohen Συν?έσεις και μέ?οδοι προς πραγματοποίηση αντισύλληψης.
EP0300630A3 (en) * 1987-07-03 1990-03-28 Schering Agrochemicals Limited Melatonin for regulating animal reproduction
EP0305194A3 (en) * 1987-08-28 1990-03-28 Schering Agrochemicals Limited Veterinary composition
US4945103A (en) * 1989-01-17 1990-07-31 Michael Cohen Method of treating pre-menstrual syndrome
IN170311B (enExample) * 1989-01-17 1992-03-14 Cohen Michael
GR900100024A (el) * 1989-01-17 1991-06-07 Amr Int Μέθοδος θεραπείας του προεμμηνορροϊκού συνδρόμου.
NZ233697A (en) * 1989-05-17 1996-12-20 Applied Med Res Ltd Contraceptive composition comprising a melatonin analogue and a progestogen and/or an estrogen
BR9007382A (pt) * 1989-05-17 1992-04-28 Michael Cohen Composicoes e metodos de efetuar a contracepcao
IT1243193B (it) * 1990-08-10 1994-05-24 Medea Res Srl Composizioni farmaceutiche orali a base di melatonina
EP0483077B1 (en) * 1990-09-28 1995-12-06 I.F.L.O. S.a.s. di Giorgio e Aldo Laguzzi A method for carrying out the synthesis of a contraceptive and menstrual cycle controlling drug having oncostatic, antikinetosic, preventive and therapeutic properties for treatment of mammary tumours and melanomas.
DE122007000073I1 (de) * 1991-05-09 2008-01-31 Neurim Pharma 1991 Melatonin enthaltene Arzneimittel
EP0608362A1 (en) * 1991-10-18 1994-08-03 Alza Corporation Device for the transdermal administration of melatonin
US5196435A (en) * 1991-11-21 1993-03-23 Eli Lilly And Company Melatonin derivatives and combinations with antiestrogen compounds for treating mammalian breast carcinoma
DK0565296T3 (da) * 1992-04-07 1996-12-09 Neurim Pharma 1991 Anvendelse af melatonin til fremstilling af et lægemiddel til behandling af godartet prostatahyperplasi
US5792785A (en) * 1995-11-24 1998-08-11 Equitech Laboratories, Inc. Method for enhancing pregnancy success in an animal
US6403631B1 (en) 1995-11-24 2002-06-11 Equitech Laboratories, Inc. Method and compositions for enhancing pregnancy success in an animal
US6028064A (en) * 1996-09-13 2000-02-22 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of progestin products
US6620836B1 (en) * 1997-01-22 2003-09-16 Jay Patrick Antiarrhythmic and tranquilizer composition and treatment
DE19739916C2 (de) * 1997-09-11 2001-09-13 Hesch Rolf Dieter Verwendung einer Kombination aus einem Gestagen und einem Estrogen zur kontinuierlichen Ovulationshemmung und ggf. gleichzeitigen Behandlung und/oder Prophylaxe von Tumoren der Brustdrüsen
EP1030669A2 (en) 1997-11-14 2000-08-30 Akzo Nobel N.V. Progestogen-antiprogestogen regimens
US6133453A (en) * 1998-05-15 2000-10-17 Pharm-Eco Laboratories, Inc. Method for making substituted indoles
US6855703B1 (en) 2000-03-10 2005-02-15 Endeavor Pharmaceuticals Pharmaceutical compositions of conjugated estrogens and methods of analyzing mixtures containing estrogenic compounds
US7459445B2 (en) * 2000-03-10 2008-12-02 Duramed Pharmaceuticals, Inc. Estrogenic compounds and topical pharmaceutical formulations of the same
US6660726B2 (en) 2000-03-10 2003-12-09 Endeavor Pharmaceuticals Estrogenic compounds, pharmaceutical compositions thereof, and methods of using same
US7989436B2 (en) 2003-07-23 2011-08-02 Duramed Pharmaceuticals, Inc. Estrogenic compounds and pharmaceutical formulations comprising the same
US20040176336A1 (en) * 2000-03-21 2004-09-09 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US20050113351A1 (en) * 2000-03-21 2005-05-26 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US20030139384A1 (en) * 2000-08-30 2003-07-24 Dudley Robert E. Method for treating erectile dysfunction and increasing libido in men
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
EP1315502B1 (en) * 2000-08-30 2010-03-17 Unimed Pharmaceuticals, LLC Method for treating erectile dysfunction and increasing libido in men
AU2003230644A1 (en) * 2002-03-14 2003-09-29 Ercole L. Cavalieri A unifying mechanism and methods to prevent cancer and neurodegenerative diseases
US6992075B2 (en) * 2003-04-04 2006-01-31 Barr Laboratories, Inc. C(14) estrogenic compounds
WO2004091535A2 (en) * 2003-04-11 2004-10-28 Barr Laboratories, Inc. Methods of administering estrogens and progestins
WO2005023241A1 (en) 2003-09-09 2005-03-17 Fumapharm Ag The use of fumaric acid derivatives for treating cardiac insufficiency, and asthma
EP1755618A1 (en) * 2004-05-26 2007-02-28 Wyeth a Corporation of the State of Delaware Compositions and methods for treatment of premenstrual dysphoric disorder
DK1799196T3 (en) 2004-10-08 2016-08-15 Forward Pharma As Controlled release pharmaceutical compositions comprising a fumaric acid ester
PT2450041T (pt) 2005-10-12 2018-11-16 Unimed Pharmaceuticals Llc Gel de testosterona melhorado e método para a sua utilização
US20090281518A1 (en) * 2006-09-13 2009-11-12 Koninklijke Philips Electronics N.V. Device for automatic adjustment of the dose of melatonin and/or delivery of melatonin
LT2653873T (lt) 2007-02-08 2022-10-10 Biogen Ma Inc. Kompozicijos ir naudojimas, skirti išsėtinei sklerozei gydyti
DE102008036825A1 (de) * 2008-08-05 2010-02-11 Aicuris Gmbh & Co. Kg Schwangerschaftsvermeidung durch Gestagene
FR2937862B1 (fr) * 2008-11-03 2010-11-19 Mohammed Ridha Chakroun Kit contraceptif
EP3124023B1 (en) * 2014-03-27 2023-08-30 Servicio Andaluz De Salud Durable preparation of an injectable of melatonin exhibiting long-term stability

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4628051A (en) * 1983-09-26 1986-12-09 Ortho Pharmaceutical Corporation Triphasic oral contraceptive

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4087444A (en) * 1976-09-08 1978-05-02 Eli Lilly And Company Amides as ovulation inhibitors
DE2967049D1 (en) * 1978-04-11 1984-07-19 Efamol Ltd Pharmaceutical and dietary composition comprising gamma-linolenic acids
US4425339A (en) * 1981-04-09 1984-01-10 Syntex (U.S.A.) Inc. Treatment of menopausal symptoms
US4390531A (en) * 1981-08-10 1983-06-28 Syntex Pharmaceuticals International Ltd. Method of contraception using peak progestogen dosage
US4614807A (en) * 1984-10-04 1986-09-30 Eli Lilly And Company 6,7-dihalomelatonins
US4746674A (en) * 1985-08-27 1988-05-24 Cellena (Cell Engineering) Ag Melatonin compositions and uses thereof
ATE77230T1 (de) * 1985-03-04 1992-07-15 Cell Eng Ag Melatoninhaltige mittel sowie deren verwendungen.
US4997845A (en) * 1987-02-02 1991-03-05 Eli Lilly And Company β-alkylmelatonins as ovulation inhibitors

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4628051A (en) * 1983-09-26 1986-12-09 Ortho Pharmaceutical Corporation Triphasic oral contraceptive

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Машковский М.Д. Лекарственны е средства. Ч.1. - М.: Медицина, 1987, с.594 и 595. *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017003321A3 (ru) * 2015-07-01 2017-03-23 Общество с ограниченной ответственностью "Научно-внедренческий центр Агроветзащита" Способ регулирования полового поведения и контрацепции самок млекопитающих
RU2617518C2 (ru) * 2015-07-01 2017-04-25 Общество с ограниченной ответственностью "Научно-внедренческий центр Агроветзащита" Способ регулирования полового поведения и контрацепции самок млекопитающих
EA036143B1 (ru) * 2015-07-01 2020-10-05 Общество с ограниченной ответственностью "Научно-внедренческий центр Агроветзащита" Способ регулирования полового поведения и контрацепции самок млекопитающих
RU2616252C2 (ru) * 2015-08-04 2017-04-13 Общество с ограниченной ответственностью "Научно-внедренческий центр Агроветзащита" Способ регулирования полового поведения самцов млекопитающих

Also Published As

Publication number Publication date
NZ223989A (en) 1991-08-27
ES2009251A6 (es) 1989-09-16
BG51075A1 (en) 1993-02-15
AU5513494A (en) 1994-04-14
IL85814A0 (en) 1990-02-09
AU628784B2 (en) 1992-09-24
US4855305A (en) 1989-08-08
EG18583A (en) 1993-06-30
PH26709A (en) 1992-09-15
EP0354921A4 (en) 1991-08-07
CA1322527C (en) 1993-09-28
EP0354921B1 (en) 1996-10-09
DE3855606D1 (de) 1996-11-14
JP2965160B2 (ja) 1999-10-18
ATE143807T1 (de) 1996-10-15
CN88101379A (zh) 1988-10-05
OA09134A (en) 1991-10-31
AU8693891A (en) 1991-12-19
IL85814A (en) 1992-05-25
IN166946B (enExample) 1990-08-11
CN1041383C (zh) 1998-12-30
FI894423A7 (fi) 1989-09-19
ZA882079B (en) 1988-09-15
FI894423A0 (fi) 1989-09-19
AU676523B2 (en) 1997-03-13
JPH02502724A (ja) 1990-08-30
DD269557A5 (de) 1989-07-05
EP0354921A1 (en) 1990-02-21
HUT52954A (en) 1990-09-28
HU208487B (en) 1993-11-29
BR8807426A (pt) 1990-04-10
PT87053A (pt) 1989-03-30
PT87053B (pt) 1993-09-30
FI894423L (fi) 1989-09-19
JPH1171276A (ja) 1999-03-16
WO1988007370A1 (en) 1988-10-06
GR1002146B (en) 1996-02-19
DE3855606T2 (de) 1997-02-13
KR890700349A (ko) 1989-04-24
AU1683088A (en) 1988-11-02
GR880100177A (el) 1989-01-31

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20050323