ATE143807T1 - Verwendung von melatonin zur herstellung einer kontrazeptiven zusammensetzung - Google Patents

Verwendung von melatonin zur herstellung einer kontrazeptiven zusammensetzung

Info

Publication number
ATE143807T1
ATE143807T1 AT88904025T AT88904025T ATE143807T1 AT E143807 T1 ATE143807 T1 AT E143807T1 AT 88904025 T AT88904025 T AT 88904025T AT 88904025 T AT88904025 T AT 88904025T AT E143807 T1 ATE143807 T1 AT E143807T1
Authority
AT
Austria
Prior art keywords
melatonin
preparing
contraceptive composition
progestogen
ovulation
Prior art date
Application number
AT88904025T
Other languages
English (en)
Inventor
Michael Cohen
Original Assignee
Applied Med Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Med Res Ltd filed Critical Applied Med Res Ltd
Application granted granted Critical
Publication of ATE143807T1 publication Critical patent/ATE143807T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Seeds, Soups, And Other Foods (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
AT88904025T 1987-03-23 1988-03-22 Verwendung von melatonin zur herstellung einer kontrazeptiven zusammensetzung ATE143807T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/029,229 US4855305A (en) 1987-03-23 1987-03-23 Compositions and methods of effecting contraception utilizing melatonin

Publications (1)

Publication Number Publication Date
ATE143807T1 true ATE143807T1 (de) 1996-10-15

Family

ID=21847942

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88904025T ATE143807T1 (de) 1987-03-23 1988-03-22 Verwendung von melatonin zur herstellung einer kontrazeptiven zusammensetzung

Country Status (26)

Country Link
US (1) US4855305A (de)
EP (1) EP0354921B1 (de)
JP (2) JP2965160B2 (de)
KR (1) KR890700349A (de)
CN (1) CN1041383C (de)
AT (1) ATE143807T1 (de)
AU (3) AU628784B2 (de)
BG (1) BG51075A1 (de)
BR (1) BR8807426A (de)
CA (1) CA1322527C (de)
DD (1) DD269557A5 (de)
DE (1) DE3855606T2 (de)
EG (1) EG18583A (de)
ES (1) ES2009251A6 (de)
FI (1) FI894423L (de)
GR (1) GR1002146B (de)
HU (1) HU208487B (de)
IL (1) IL85814A (de)
IN (1) IN166946B (de)
NZ (1) NZ223989A (de)
OA (1) OA09134A (de)
PH (1) PH26709A (de)
PT (1) PT87053B (de)
RU (1) RU2114621C1 (de)
WO (1) WO1988007370A1 (de)
ZA (1) ZA882079B (de)

Families Citing this family (44)

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Publication number Priority date Publication date Assignee Title
GR1001395B (el) * 1987-03-23 1993-10-29 Michael Cohen Συν?έσεις και μέ?οδοι προς πραγματοποίηση αντισύλληψης.
EP0300630A3 (de) * 1987-07-03 1990-03-28 Schering Agrochemicals Limited Melatonin zur Steuerung der Fortpflanzung von Tieren
IL87574A0 (en) * 1987-08-28 1989-01-31 Regulin Ltd Composition for regulating animal reproduction containing an indole derivative
GR900100024A (el) * 1989-01-17 1991-06-07 Amr Int Μέθοδος θεραπείας του προεμμηνορροϊκού συνδρόμου.
IN170311B (de) * 1989-01-17 1992-03-14 Cohen Michael
US4945103A (en) * 1989-01-17 1990-07-31 Michael Cohen Method of treating pre-menstrual syndrome
BR9007382A (pt) * 1989-05-17 1992-04-28 Michael Cohen Composicoes e metodos de efetuar a contracepcao
NZ233697A (en) * 1989-05-17 1996-12-20 Applied Med Res Ltd Contraceptive composition comprising a melatonin analogue and a progestogen and/or an estrogen
IT1243193B (it) * 1990-08-10 1994-05-24 Medea Res Srl Composizioni farmaceutiche orali a base di melatonina
DK0483077T3 (da) * 1990-09-28 1996-04-15 I F L O S A S Di Giorgio E Ald Fremgangsmåde til syntese af et kontraceptivt og menstruationscyklus-kontrollerende lægemiddel med onkostatiske, antikinetosiske, præventive og terapeutiske egenskaber til behandling af brysttumorer og melanomer
DK0518468T3 (da) * 1991-05-09 2000-01-31 Neurim Pharma 1991 Melatoninholdige sammensætninger
WO1993007870A1 (en) * 1991-10-18 1993-04-29 Alza Corporation Device for the transdermal administration of melatonin
US5196435A (en) * 1991-11-21 1993-03-23 Eli Lilly And Company Melatonin derivatives and combinations with antiestrogen compounds for treating mammalian breast carcinoma
SG41955A1 (en) * 1992-04-07 1997-08-15 Neurim Pharma 1991 Use of melatonin for the manufacture of a medicament for the treatment of benign prostatic hyperplasia
US5792785A (en) * 1995-11-24 1998-08-11 Equitech Laboratories, Inc. Method for enhancing pregnancy success in an animal
US6403631B1 (en) 1995-11-24 2002-06-11 Equitech Laboratories, Inc. Method and compositions for enhancing pregnancy success in an animal
US6028064A (en) * 1996-09-13 2000-02-22 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of progestin products
US6620836B1 (en) * 1997-01-22 2003-09-16 Jay Patrick Antiarrhythmic and tranquilizer composition and treatment
DE19739916C2 (de) * 1997-09-11 2001-09-13 Hesch Rolf Dieter Verwendung einer Kombination aus einem Gestagen und einem Estrogen zur kontinuierlichen Ovulationshemmung und ggf. gleichzeitigen Behandlung und/oder Prophylaxe von Tumoren der Brustdrüsen
HUP0100542A3 (en) 1997-11-14 2001-10-29 Akzo Nobel Nv Progestogen and antiprogestogen containing kit, process for its preparation and use of the compounds for the preparation of contraseptives
US6133453A (en) * 1998-05-15 2000-10-17 Pharm-Eco Laboratories, Inc. Method for making substituted indoles
US6660726B2 (en) * 2000-03-10 2003-12-09 Endeavor Pharmaceuticals Estrogenic compounds, pharmaceutical compositions thereof, and methods of using same
US6855703B1 (en) 2000-03-10 2005-02-15 Endeavor Pharmaceuticals Pharmaceutical compositions of conjugated estrogens and methods of analyzing mixtures containing estrogenic compounds
US7989436B2 (en) 2003-07-23 2011-08-02 Duramed Pharmaceuticals, Inc. Estrogenic compounds and pharmaceutical formulations comprising the same
US7459445B2 (en) * 2000-03-10 2008-12-02 Duramed Pharmaceuticals, Inc. Estrogenic compounds and topical pharmaceutical formulations of the same
US20050113351A1 (en) * 2000-03-21 2005-05-26 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US20040176336A1 (en) * 2000-03-21 2004-09-09 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
NZ524601A (en) * 2000-08-30 2006-04-28 Unimed Pharmaceuticals Inc Method for treating erectile dysfunction and increasing libido in men
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
US20030139384A1 (en) * 2000-08-30 2003-07-24 Dudley Robert E. Method for treating erectile dysfunction and increasing libido in men
AU2003230644A1 (en) * 2002-03-14 2003-09-29 Ercole L. Cavalieri A unifying mechanism and methods to prevent cancer and neurodegenerative diseases
US6992075B2 (en) * 2003-04-04 2006-01-31 Barr Laboratories, Inc. C(14) estrogenic compounds
EP1622623A4 (de) * 2003-04-11 2009-03-18 Barr Lab Inc Verfahren zur verabreichung von östrogenen und gestagenen
EP1913942B1 (de) 2003-09-09 2009-11-11 Biogen Idec International GmbH Verwendung von Fumarsäurederivaten zur Inhibition der PDGF-induzierten Thymidin-aufnahme bei glatten Bronchialmuskelzellen und zur Inhibition der Proliferation von glatten Bronchialmuskelzellen
MXPA06013418A (es) * 2004-05-26 2007-01-23 Wyeth Corp Composiciones y metodos para el tratamiento del trastorno disforico premenstrual.
PL2316430T3 (pl) 2004-10-08 2012-11-30 Forward Pharma As Kompozycje farmaceutyczne o kontrolowanym uwalnianiu, zawierające ester kwasu fumarowego
JP5584415B2 (ja) 2005-10-12 2014-09-03 ユニメッド・ファーマシューティカルズ・エルエルシー 改良したテストステロンゲル製剤及び使用の方法
EP2068695A2 (de) * 2006-09-13 2009-06-17 Koninklijke Philips Electronics N.V. Vorrichtung zur automatischen anpassung einer melatonin-dosis und/oder einer melatonin-verabreichung
EP2680009A1 (de) 2007-02-08 2014-01-01 Biogen Idec MA Inc. Nrf2-screening-Assays sowie entsprechende Verfahren und Zusammensetzungen
DE102008036825A1 (de) * 2008-08-05 2010-02-11 Aicuris Gmbh & Co. Kg Schwangerschaftsvermeidung durch Gestagene
FR2937862B1 (fr) * 2008-11-03 2010-11-19 Mohammed Ridha Chakroun Kit contraceptif
WO2015144965A1 (es) * 2014-03-27 2015-10-01 Servicio Andaluz De Salud Preparación duradera de inyectable de melatonina estable a largo plazo
RU2617518C2 (ru) * 2015-07-01 2017-04-25 Общество с ограниченной ответственностью "Научно-внедренческий центр Агроветзащита" Способ регулирования полового поведения и контрацепции самок млекопитающих
RU2616252C2 (ru) * 2015-08-04 2017-04-13 Общество с ограниченной ответственностью "Научно-внедренческий центр Агроветзащита" Способ регулирования полового поведения самцов млекопитающих

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4087444A (en) * 1976-09-08 1978-05-02 Eli Lilly And Company Amides as ovulation inhibitors
EP0004770B1 (de) * 1978-04-11 1984-06-13 Efamol Limited Pharmazeutische und diätetische Zusammensetzung mit Gehalt an Gamma-Linolensäuren
US4425339A (en) * 1981-04-09 1984-01-10 Syntex (U.S.A.) Inc. Treatment of menopausal symptoms
US4390531A (en) * 1981-08-10 1983-06-28 Syntex Pharmaceuticals International Ltd. Method of contraception using peak progestogen dosage
US4628051A (en) * 1983-09-26 1986-12-09 Ortho Pharmaceutical Corporation Triphasic oral contraceptive
US4614807A (en) * 1984-10-04 1986-09-30 Eli Lilly And Company 6,7-dihalomelatonins
US4746674A (en) * 1985-08-27 1988-05-24 Cellena (Cell Engineering) Ag Melatonin compositions and uses thereof
ATE77230T1 (de) * 1985-03-04 1992-07-15 Cell Eng Ag Melatoninhaltige mittel sowie deren verwendungen.
US4997845A (en) * 1987-02-02 1991-03-05 Eli Lilly And Company β-alkylmelatonins as ovulation inhibitors

Also Published As

Publication number Publication date
PT87053A (pt) 1989-03-30
CN1041383C (zh) 1998-12-30
CN88101379A (zh) 1988-10-05
ZA882079B (en) 1988-09-15
IL85814A (en) 1992-05-25
KR890700349A (ko) 1989-04-24
AU628784B2 (en) 1992-09-24
FI894423A0 (fi) 1989-09-19
IL85814A0 (en) 1990-02-09
WO1988007370A1 (en) 1988-10-06
CA1322527C (en) 1993-09-28
AU1683088A (en) 1988-11-02
GR1002146B (en) 1996-02-19
EP0354921A4 (en) 1991-08-07
DE3855606T2 (de) 1997-02-13
FI894423A7 (fi) 1989-09-19
AU5513494A (en) 1994-04-14
OA09134A (en) 1991-10-31
PH26709A (en) 1992-09-15
HUT52954A (en) 1990-09-28
HU208487B (en) 1993-11-29
AU676523B2 (en) 1997-03-13
DD269557A5 (de) 1989-07-05
US4855305A (en) 1989-08-08
EG18583A (en) 1993-06-30
BR8807426A (pt) 1990-04-10
PT87053B (pt) 1993-09-30
RU2114621C1 (ru) 1998-07-10
BG51075A1 (en) 1993-02-15
EP0354921B1 (de) 1996-10-09
ES2009251A6 (es) 1989-09-16
DE3855606D1 (de) 1996-11-14
JPH02502724A (ja) 1990-08-30
IN166946B (de) 1990-08-11
GR880100177A (el) 1989-01-31
EP0354921A1 (de) 1990-02-21
NZ223989A (en) 1991-08-27
JPH1171276A (ja) 1999-03-16
JP2965160B2 (ja) 1999-10-18
FI894423L (fi) 1989-09-19
AU8693891A (en) 1991-12-19

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee