DD269557A5 - Verfahren zur herstellung einer zusammensetzung zur wirksamen prephylaxe von brustkrebs bei frauen und zur empfaengnisverhuetung - Google Patents

Verfahren zur herstellung einer zusammensetzung zur wirksamen prephylaxe von brustkrebs bei frauen und zur empfaengnisverhuetung Download PDF

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Publication number
DD269557A5
DD269557A5 DD88313924A DD31392488A DD269557A5 DD 269557 A5 DD269557 A5 DD 269557A5 DD 88313924 A DD88313924 A DD 88313924A DD 31392488 A DD31392488 A DD 31392488A DD 269557 A5 DD269557 A5 DD 269557A5
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DD
German Democratic Republic
Prior art keywords
melatonin
progestogen
estrogen
cycle
women
Prior art date
Application number
DD88313924A
Other languages
German (de)
English (en)
Inventor
Michael Cohen
Original Assignee
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Publication date
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Publication of DD269557A5 publication Critical patent/DD269557A5/de

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Seeds, Soups, And Other Foods (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DD88313924A 1987-03-23 1988-03-23 Verfahren zur herstellung einer zusammensetzung zur wirksamen prephylaxe von brustkrebs bei frauen und zur empfaengnisverhuetung DD269557A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/029,229 US4855305A (en) 1987-03-23 1987-03-23 Compositions and methods of effecting contraception utilizing melatonin

Publications (1)

Publication Number Publication Date
DD269557A5 true DD269557A5 (de) 1989-07-05

Family

ID=21847942

Family Applications (1)

Application Number Title Priority Date Filing Date
DD88313924A DD269557A5 (de) 1987-03-23 1988-03-23 Verfahren zur herstellung einer zusammensetzung zur wirksamen prephylaxe von brustkrebs bei frauen und zur empfaengnisverhuetung

Country Status (26)

Country Link
US (1) US4855305A (enExample)
EP (1) EP0354921B1 (enExample)
JP (2) JP2965160B2 (enExample)
KR (1) KR890700349A (enExample)
CN (1) CN1041383C (enExample)
AT (1) ATE143807T1 (enExample)
AU (3) AU628784B2 (enExample)
BG (1) BG51075A1 (enExample)
BR (1) BR8807426A (enExample)
CA (1) CA1322527C (enExample)
DD (1) DD269557A5 (enExample)
DE (1) DE3855606T2 (enExample)
EG (1) EG18583A (enExample)
ES (1) ES2009251A6 (enExample)
FI (1) FI894423L (enExample)
GR (1) GR1002146B (enExample)
HU (1) HU208487B (enExample)
IL (1) IL85814A (enExample)
IN (1) IN166946B (enExample)
NZ (1) NZ223989A (enExample)
OA (1) OA09134A (enExample)
PH (1) PH26709A (enExample)
PT (1) PT87053B (enExample)
RU (1) RU2114621C1 (enExample)
WO (1) WO1988007370A1 (enExample)
ZA (1) ZA882079B (enExample)

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GR1001395B (el) * 1987-03-23 1993-10-29 Michael Cohen Συν?έσεις και μέ?οδοι προς πραγματοποίηση αντισύλληψης.
EP0300630A3 (en) * 1987-07-03 1990-03-28 Schering Agrochemicals Limited Melatonin for regulating animal reproduction
IL87574A0 (en) * 1987-08-28 1989-01-31 Regulin Ltd Composition for regulating animal reproduction containing an indole derivative
GR900100024A (el) * 1989-01-17 1991-06-07 Amr Int Μέθοδος θεραπείας του προεμμηνορροϊκού συνδρόμου.
IN170311B (enExample) * 1989-01-17 1992-03-14 Cohen Michael
US4945103A (en) * 1989-01-17 1990-07-31 Michael Cohen Method of treating pre-menstrual syndrome
AU644367B2 (en) * 1989-05-17 1993-12-09 Applied Medical Research Ltd Use of melatonin derivatives for effecting contraception
NZ233697A (en) * 1989-05-17 1996-12-20 Applied Med Res Ltd Contraceptive composition comprising a melatonin analogue and a progestogen and/or an estrogen
IT1243193B (it) * 1990-08-10 1994-05-24 Medea Res Srl Composizioni farmaceutiche orali a base di melatonina
EP0483077B1 (en) * 1990-09-28 1995-12-06 I.F.L.O. S.a.s. di Giorgio e Aldo Laguzzi A method for carrying out the synthesis of a contraceptive and menstrual cycle controlling drug having oncostatic, antikinetosic, preventive and therapeutic properties for treatment of mammary tumours and melanomas.
EP0518468B1 (en) * 1991-05-09 1999-06-30 Neurim Pharmaceuticals (1991) Limited Melatonin containing compositions
PT100973A (pt) * 1991-10-18 1994-06-30 Alza Corp Dispositivo e composicoes farmaceuticas para a administracao de melatonina por via transdermica
US5196435A (en) * 1991-11-21 1993-03-23 Eli Lilly And Company Melatonin derivatives and combinations with antiestrogen compounds for treating mammalian breast carcinoma
ATE141051T1 (de) * 1992-04-07 1996-08-15 Neurim Pharma 1991 Verwendung von melatonin zur herstellung eines arzneimittels zur behandlung der gutartigen prostatahyperplasie
US5792785A (en) * 1995-11-24 1998-08-11 Equitech Laboratories, Inc. Method for enhancing pregnancy success in an animal
US6403631B1 (en) 1995-11-24 2002-06-11 Equitech Laboratories, Inc. Method and compositions for enhancing pregnancy success in an animal
US6028064A (en) * 1996-09-13 2000-02-22 New Life Pharmaceuticals Inc. Prevention of ovarian cancer by administration of progestin products
US6620836B1 (en) * 1997-01-22 2003-09-16 Jay Patrick Antiarrhythmic and tranquilizer composition and treatment
DE19739916C2 (de) * 1997-09-11 2001-09-13 Hesch Rolf Dieter Verwendung einer Kombination aus einem Gestagen und einem Estrogen zur kontinuierlichen Ovulationshemmung und ggf. gleichzeitigen Behandlung und/oder Prophylaxe von Tumoren der Brustdrüsen
WO1999025360A2 (en) 1997-11-14 1999-05-27 Akzo Nobel N.V. Progestogen-antiprogestogen regimens
US6133453A (en) * 1998-05-15 2000-10-17 Pharm-Eco Laboratories, Inc. Method for making substituted indoles
US7459445B2 (en) * 2000-03-10 2008-12-02 Duramed Pharmaceuticals, Inc. Estrogenic compounds and topical pharmaceutical formulations of the same
US6855703B1 (en) 2000-03-10 2005-02-15 Endeavor Pharmaceuticals Pharmaceutical compositions of conjugated estrogens and methods of analyzing mixtures containing estrogenic compounds
US6660726B2 (en) * 2000-03-10 2003-12-09 Endeavor Pharmaceuticals Estrogenic compounds, pharmaceutical compositions thereof, and methods of using same
US7989436B2 (en) 2003-07-23 2011-08-02 Duramed Pharmaceuticals, Inc. Estrogenic compounds and pharmaceutical formulations comprising the same
US20040176336A1 (en) * 2000-03-21 2004-09-09 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US20050113351A1 (en) * 2000-03-21 2005-05-26 Rodriguez Gustavo C. Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium
US20030139384A1 (en) * 2000-08-30 2003-07-24 Dudley Robert E. Method for treating erectile dysfunction and increasing libido in men
IL154692A0 (en) * 2000-08-30 2003-09-17 Unimed Pharmaceuticals Inc Method of treating erectile dysfunction and increasing libido in men
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
WO2003077900A1 (en) * 2002-03-14 2003-09-25 Prevention, L.L.C. A unifying mechanism and methods to prevent cancer and neurodegenerative diseases
US6992075B2 (en) * 2003-04-04 2006-01-31 Barr Laboratories, Inc. C(14) estrogenic compounds
WO2004091535A2 (en) * 2003-04-11 2004-10-28 Barr Laboratories, Inc. Methods of administering estrogens and progestins
EP1913942B1 (en) 2003-09-09 2009-11-11 Biogen Idec International GmbH The use of fumaric acid derivatives for inhibition of PGF-induced thymidine uptake of bronchial smooth muscle cells and for inhibition of bronchial smooth cells proliferation
MXPA06013418A (es) * 2004-05-26 2007-01-23 Wyeth Corp Composiciones y metodos para el tratamiento del trastorno disforico premenstrual.
DE14172396T1 (de) 2004-10-08 2015-01-08 Forward Pharma A/S Gesteuerte Freisetzung von pharmazeutischen Zusammensetzungen mit Fumarinsäureester
PL1937276T3 (pl) 2005-10-12 2013-07-31 Unimed Pharmaceuticals Llc Ulepszony żel z testosteronem i sposób zastosowania
US20090281518A1 (en) * 2006-09-13 2009-11-12 Koninklijke Philips Electronics N.V. Device for automatic adjustment of the dose of melatonin and/or delivery of melatonin
US20110112196A1 (en) 2007-02-08 2011-05-12 Matvey E Lukashev Nrf2 screening assays and related methods and compositions
DE102008036825A1 (de) * 2008-08-05 2010-02-11 Aicuris Gmbh & Co. Kg Schwangerschaftsvermeidung durch Gestagene
FR2937862B1 (fr) * 2008-11-03 2010-11-19 Mohammed Ridha Chakroun Kit contraceptif
WO2015144965A1 (es) * 2014-03-27 2015-10-01 Servicio Andaluz De Salud Preparación duradera de inyectable de melatonina estable a largo plazo
RU2617518C2 (ru) * 2015-07-01 2017-04-25 Общество с ограниченной ответственностью "Научно-внедренческий центр Агроветзащита" Способ регулирования полового поведения и контрацепции самок млекопитающих
RU2616252C2 (ru) * 2015-08-04 2017-04-13 Общество с ограниченной ответственностью "Научно-внедренческий центр Агроветзащита" Способ регулирования полового поведения самцов млекопитающих

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US4087444A (en) * 1976-09-08 1978-05-02 Eli Lilly And Company Amides as ovulation inhibitors
EP0004770B1 (en) * 1978-04-11 1984-06-13 Efamol Limited Pharmaceutical and dietary composition comprising gamma-linolenic acids
US4425339A (en) * 1981-04-09 1984-01-10 Syntex (U.S.A.) Inc. Treatment of menopausal symptoms
US4390531A (en) * 1981-08-10 1983-06-28 Syntex Pharmaceuticals International Ltd. Method of contraception using peak progestogen dosage
US4628051A (en) * 1983-09-26 1986-12-09 Ortho Pharmaceutical Corporation Triphasic oral contraceptive
US4614807A (en) * 1984-10-04 1986-09-30 Eli Lilly And Company 6,7-dihalomelatonins
US4746674A (en) * 1985-08-27 1988-05-24 Cellena (Cell Engineering) Ag Melatonin compositions and uses thereof
DE3685696T2 (de) * 1985-03-04 1993-01-14 Cell Eng Ag Melatoninhaltige mittel sowie deren verwendungen.
US4997845A (en) * 1987-02-02 1991-03-05 Eli Lilly And Company β-alkylmelatonins as ovulation inhibitors

Also Published As

Publication number Publication date
HUT52954A (en) 1990-09-28
BR8807426A (pt) 1990-04-10
IL85814A (en) 1992-05-25
EP0354921B1 (en) 1996-10-09
HU208487B (en) 1993-11-29
BG51075A1 (en) 1993-02-15
US4855305A (en) 1989-08-08
AU8693891A (en) 1991-12-19
DE3855606D1 (de) 1996-11-14
AU628784B2 (en) 1992-09-24
ZA882079B (en) 1988-09-15
NZ223989A (en) 1991-08-27
PH26709A (en) 1992-09-15
AU676523B2 (en) 1997-03-13
EP0354921A4 (en) 1991-08-07
JPH1171276A (ja) 1999-03-16
GR1002146B (en) 1996-02-19
GR880100177A (el) 1989-01-31
PT87053A (pt) 1989-03-30
ATE143807T1 (de) 1996-10-15
EP0354921A1 (en) 1990-02-21
KR890700349A (ko) 1989-04-24
AU5513494A (en) 1994-04-14
AU1683088A (en) 1988-11-02
PT87053B (pt) 1993-09-30
FI894423A0 (fi) 1989-09-19
IL85814A0 (en) 1990-02-09
DE3855606T2 (de) 1997-02-13
OA09134A (en) 1991-10-31
JP2965160B2 (ja) 1999-10-18
EG18583A (en) 1993-06-30
JPH02502724A (ja) 1990-08-30
RU2114621C1 (ru) 1998-07-10
WO1988007370A1 (en) 1988-10-06
IN166946B (enExample) 1990-08-11
CN88101379A (zh) 1988-10-05
CA1322527C (en) 1993-09-28
CN1041383C (zh) 1998-12-30
FI894423A7 (fi) 1989-09-19
FI894423L (fi) 1989-09-19
ES2009251A6 (es) 1989-09-16

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Legal Events

Date Code Title Description
A5 Published as prov. exclusive patent
ENJ Ceased due to non-payment of renewal fee