RU2020114632A - Терапевтические способы, относящиеся к ингибиторам hsp90 - Google Patents

Терапевтические способы, относящиеся к ингибиторам hsp90 Download PDF

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RU2020114632A
RU2020114632A RU2020114632A RU2020114632A RU2020114632A RU 2020114632 A RU2020114632 A RU 2020114632A RU 2020114632 A RU2020114632 A RU 2020114632A RU 2020114632 A RU2020114632 A RU 2020114632A RU 2020114632 A RU2020114632 A RU 2020114632A
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inhibitor
flt3
cancer
aml
subject
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RU2020114632A
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RU2020114632A3 (enExample
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Хенри ЛИХЕНШТЕЙН
Нил БИХАРРИ
Шон ЛАНДРЕТТЕ
София ГЭЙЛ
Джефф ГРОЦКЕ
Мариленс ЭРНАНДЕС
Питер Р ЯНГ
Джонатан М. РОТБЕРГ
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ЭйАй ТЕРАПЬЮТИКС, ИНК.
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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RU2020114632A 2017-09-27 2018-09-27 Терапевтические способы, относящиеся к ингибиторам hsp90 RU2020114632A (ru)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762563991P 2017-09-27 2017-09-27
US62/563,991 2017-09-27
US201762587886P 2017-11-17 2017-11-17
US62/587,886 2017-11-17
US201862688079P 2018-06-21 2018-06-21
US62/688,079 2018-06-21
PCT/US2018/053025 WO2019067666A1 (en) 2017-09-27 2018-09-27 THERAPEUTIC METHODS RELATING TO HSP90 INHIBITORS

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RU2020114632A true RU2020114632A (ru) 2021-10-28
RU2020114632A3 RU2020114632A3 (enExample) 2022-04-18

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US (2) US20190091229A1 (enExample)
EP (1) EP3687542A1 (enExample)
JP (1) JP2020535173A (enExample)
KR (1) KR20200077518A (enExample)
CN (1) CN111372588A (enExample)
AU (1) AU2018341571A1 (enExample)
BR (1) BR112020006009A2 (enExample)
CA (1) CA3076915A1 (enExample)
IL (1) IL273585A (enExample)
MX (1) MX2020003959A (enExample)
RU (1) RU2020114632A (enExample)
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WO2018144680A1 (en) 2017-02-03 2018-08-09 Lam Therapeutics, Inc. Methods for treating cancer using hsp90 inhibitors
US12472175B2 (en) * 2019-02-26 2025-11-18 Oregon Health & Science University Methods of treating venetoclax-resistant acute myeloid leukemia
BR112021019489A2 (pt) * 2019-03-29 2022-02-08 Univ Texas Compostos com atividade antitumoral contra células cancerosas portando inserções do éxon 20 de egfr ou de her2
EP3771469A1 (en) * 2019-07-30 2021-02-03 Amgen, Inc Formulations and dosages for administering a compound that inhibits mcl1 protein
US11471451B2 (en) * 2019-08-19 2022-10-18 Arog Pharmaceuticals, Inc. Uses of crenolanib
US20220362254A1 (en) * 2019-08-22 2022-11-17 Thomas Jefferson University Methods for reprogramming cancer cells
CN114641292A (zh) * 2019-08-23 2022-06-17 光谱制药有限公司 波齐替尼与vegfr2抑制剂的组合及其用途
WO2021063340A1 (zh) * 2019-09-30 2021-04-08 江苏恒瑞医药股份有限公司 Ezh2抑制剂与免疫检查点抑制剂、酪氨酸激酶抑制剂联合在制备治疗肿瘤药物中的用途
WO2021133862A1 (en) * 2019-12-24 2021-07-01 The Regents Of The University Of California Targeting the intrinsic apoptotic machinery in glioblastoma
JP2023510426A (ja) * 2020-01-20 2023-03-13 アストラゼネカ・アクチエボラーグ 癌を治療するための上皮細胞増殖因子受容体チロシンキナーゼ阻害剤
EP4149512A4 (en) * 2020-05-12 2024-06-05 Board of Regents, The University of Texas System METHODS OF TREATMENT OF GLIOBLASTOMA
WO2022090547A1 (en) 2020-10-30 2022-05-05 Dsm Ip Assets B.V. Production of carotenoids by fermentation
US11969420B2 (en) * 2020-10-30 2024-04-30 Arog Pharmaceuticals, Inc. Combination therapy of crenolanib and apoptosis pathway agents for the treatment of proliferative disorders
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