RU2019116069A - Новые биомаркеры старения кожи человека - Google Patents
Новые биомаркеры старения кожи человека Download PDFInfo
- Publication number
- RU2019116069A RU2019116069A RU2019116069A RU2019116069A RU2019116069A RU 2019116069 A RU2019116069 A RU 2019116069A RU 2019116069 A RU2019116069 A RU 2019116069A RU 2019116069 A RU2019116069 A RU 2019116069A RU 2019116069 A RU2019116069 A RU 2019116069A
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- expression
- skin
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- hmgn1
- tubb3
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- 230000009759 skin aging Effects 0.000 title claims 4
- 239000000090 biomarker Substances 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 claims 54
- 102000004169 proteins and genes Human genes 0.000 claims 29
- 210000003491 skin Anatomy 0.000 claims 21
- 108700039143 HMGA2 Proteins 0.000 claims 12
- 102100028999 High mobility group protein HMGI-C Human genes 0.000 claims 12
- 101150073387 Hmga2 gene Proteins 0.000 claims 12
- 101000866795 Homo sapiens Non-histone chromosomal protein HMG-14 Proteins 0.000 claims 12
- 101000713575 Homo sapiens Tubulin beta-3 chain Proteins 0.000 claims 12
- 102100031353 Non-histone chromosomal protein HMG-14 Human genes 0.000 claims 12
- 102100036790 Tubulin beta-3 chain Human genes 0.000 claims 12
- 238000000034 method Methods 0.000 claims 12
- 230000032683 aging Effects 0.000 claims 9
- -1 NEB Proteins 0.000 claims 7
- 102100036659 26S proteasome non-ATPase regulatory subunit 9 Human genes 0.000 claims 6
- 102100039377 28 kDa heat- and acid-stable phosphoprotein Human genes 0.000 claims 6
- 102000003741 Actin-related protein 3 Human genes 0.000 claims 6
- 108090000104 Actin-related protein 3 Proteins 0.000 claims 6
- 102100032559 Clathrin light chain B Human genes 0.000 claims 6
- 102100027563 Cytochrome c oxidase subunit 5A, mitochondrial Human genes 0.000 claims 6
- 102100023078 Early endosome antigen 1 Human genes 0.000 claims 6
- 102100029009 High mobility group protein HMG-I/HMG-Y Human genes 0.000 claims 6
- 102100021639 Histone H2B type 1-K Human genes 0.000 claims 6
- 101001136710 Homo sapiens 26S proteasome non-ATPase regulatory subunit 9 Proteins 0.000 claims 6
- 101001035654 Homo sapiens 28 kDa heat- and acid-stable phosphoprotein Proteins 0.000 claims 6
- 101000942271 Homo sapiens Clathrin light chain B Proteins 0.000 claims 6
- 101000725076 Homo sapiens Cytochrome c oxidase subunit 5A, mitochondrial Proteins 0.000 claims 6
- 101001050162 Homo sapiens Early endosome antigen 1 Proteins 0.000 claims 6
- 101000986380 Homo sapiens High mobility group protein HMG-I/HMG-Y Proteins 0.000 claims 6
- 101000898898 Homo sapiens Histone H2B type 1-K Proteins 0.000 claims 6
- 101001042036 Homo sapiens Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial Proteins 0.000 claims 6
- 101000942713 Homo sapiens Liprin-alpha-2 Proteins 0.000 claims 6
- 101001027945 Homo sapiens Metallothionein-1E Proteins 0.000 claims 6
- 101001000104 Homo sapiens Myosin-11 Proteins 0.000 claims 6
- 101000866805 Homo sapiens Non-histone chromosomal protein HMG-17 Proteins 0.000 claims 6
- 101001133656 Homo sapiens Plasminogen activator inhibitor 1 RNA-binding protein Proteins 0.000 claims 6
- 101000596119 Homo sapiens Plastin-3 Proteins 0.000 claims 6
- 101000980965 Homo sapiens Protein CDV3 homolog Proteins 0.000 claims 6
- 101000738322 Homo sapiens Prothymosin alpha Proteins 0.000 claims 6
- 101000700735 Homo sapiens Serine/arginine-rich splicing factor 7 Proteins 0.000 claims 6
- 101000831940 Homo sapiens Stathmin Proteins 0.000 claims 6
- 101000653663 Homo sapiens T-complex protein 1 subunit epsilon Proteins 0.000 claims 6
- 101000658138 Homo sapiens Thymosin beta-10 Proteins 0.000 claims 6
- 101000658157 Homo sapiens Thymosin beta-4 Proteins 0.000 claims 6
- 101000788845 Homo sapiens Zinc finger CCCH domain-containing protein 11A Proteins 0.000 claims 6
- 102100021332 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial Human genes 0.000 claims 6
- 102100032894 Liprin-alpha-2 Human genes 0.000 claims 6
- 102100037510 Metallothionein-1E Human genes 0.000 claims 6
- 102100036639 Myosin-11 Human genes 0.000 claims 6
- 102100031346 Non-histone chromosomal protein HMG-17 Human genes 0.000 claims 6
- 102100034055 Plasminogen activator inhibitor 1 RNA-binding protein Human genes 0.000 claims 6
- 102100035220 Plastin-3 Human genes 0.000 claims 6
- 102100024920 Prefoldin subunit 2 Human genes 0.000 claims 6
- 102100024449 Protein CDV3 homolog Human genes 0.000 claims 6
- 102100037925 Prothymosin alpha Human genes 0.000 claims 6
- 102100029287 Serine/arginine-rich splicing factor 7 Human genes 0.000 claims 6
- 102100024237 Stathmin Human genes 0.000 claims 6
- 102100029886 T-complex protein 1 subunit epsilon Human genes 0.000 claims 6
- 102100034998 Thymosin beta-10 Human genes 0.000 claims 6
- 102100035000 Thymosin beta-4 Human genes 0.000 claims 6
- OKKRPWIIYQTPQF-UHFFFAOYSA-N Trimethylolpropane trimethacrylate Chemical compound CC(=C)C(=O)OCC(CC)(COC(=O)C(C)=C)COC(=O)C(C)=C OKKRPWIIYQTPQF-UHFFFAOYSA-N 0.000 claims 6
- 102100025402 Zinc finger CCCH domain-containing protein 11A Human genes 0.000 claims 6
- 108010075843 alpha-2-HS-Glycoprotein Proteins 0.000 claims 6
- 102000012005 alpha-2-HS-Glycoprotein Human genes 0.000 claims 6
- 239000000126 substance Substances 0.000 claims 6
- LTPSRQRIPCVMKQ-UHFFFAOYSA-N 2-amino-5-methylbenzenesulfonic acid Chemical compound CC1=CC=C(N)C(S(O)(=O)=O)=C1 LTPSRQRIPCVMKQ-UHFFFAOYSA-N 0.000 claims 5
- 102100032303 26S proteasome non-ATPase regulatory subunit 2 Human genes 0.000 claims 5
- 102100023679 40S ribosomal protein S28 Human genes 0.000 claims 5
- 102100024442 60S ribosomal protein L13 Human genes 0.000 claims 5
- 101100339431 Arabidopsis thaliana HMGB2 gene Proteins 0.000 claims 5
- 102100025580 Calmodulin-1 Human genes 0.000 claims 5
- 102000058063 Glucose Transporter Type 1 Human genes 0.000 claims 5
- 108700010013 HMGB1 Proteins 0.000 claims 5
- 101150021904 HMGB1 gene Proteins 0.000 claims 5
- 102100037907 High mobility group protein B1 Human genes 0.000 claims 5
- 101000590272 Homo sapiens 26S proteasome non-ATPase regulatory subunit 2 Proteins 0.000 claims 5
- 101000691550 Homo sapiens 39S ribosomal protein L13, mitochondrial Proteins 0.000 claims 5
- 101000623076 Homo sapiens 40S ribosomal protein S28 Proteins 0.000 claims 5
- 101001118201 Homo sapiens 60S ribosomal protein L13 Proteins 0.000 claims 5
- 101000984164 Homo sapiens Calmodulin-1 Proteins 0.000 claims 5
- 101001076613 Homo sapiens Immortalization up-regulated protein Proteins 0.000 claims 5
- 101000961149 Homo sapiens Immunoglobulin heavy constant gamma 4 Proteins 0.000 claims 5
- 101001027938 Homo sapiens Metallothionein-1G Proteins 0.000 claims 5
- 101001082207 Homo sapiens Parathymosin Proteins 0.000 claims 5
- 101001116674 Homo sapiens Prefoldin subunit 2 Proteins 0.000 claims 5
- 101000730802 Homo sapiens Prefoldin subunit 6 Proteins 0.000 claims 5
- 101000611053 Homo sapiens Proteasome subunit beta type-2 Proteins 0.000 claims 5
- 101000837067 Homo sapiens SH3 domain-binding glutamic acid-rich-like protein 3 Proteins 0.000 claims 5
- 101000832685 Homo sapiens Small ubiquitin-related modifier 2 Proteins 0.000 claims 5
- 101000587717 Homo sapiens Sulfide:quinone oxidoreductase, mitochondrial Proteins 0.000 claims 5
- 101000830781 Homo sapiens Tropomyosin alpha-4 chain Proteins 0.000 claims 5
- 101000806601 Homo sapiens V-type proton ATPase catalytic subunit A Proteins 0.000 claims 5
- 102100025886 Immortalization up-regulated protein Human genes 0.000 claims 5
- 102100039347 Immunoglobulin heavy constant gamma 4 Human genes 0.000 claims 5
- 102100037512 Metallothionein-1G Human genes 0.000 claims 5
- 102100027370 Parathymosin Human genes 0.000 claims 5
- 102100032926 Prefoldin subunit 6 Human genes 0.000 claims 5
- 102100040400 Proteasome subunit beta type-2 Human genes 0.000 claims 5
- 102100028643 SH3 domain-binding glutamic acid-rich-like protein 3 Human genes 0.000 claims 5
- 108091006296 SLC2A1 Proteins 0.000 claims 5
- 102100024542 Small ubiquitin-related modifier 2 Human genes 0.000 claims 5
- 102100031138 Sulfide:quinone oxidoreductase, mitochondrial Human genes 0.000 claims 5
- 102100024944 Tropomyosin alpha-4 chain Human genes 0.000 claims 5
- 102100037466 V-type proton ATPase catalytic subunit A Human genes 0.000 claims 5
- 102100030943 Glutathione S-transferase P Human genes 0.000 claims 4
- 101001010139 Homo sapiens Glutathione S-transferase P Proteins 0.000 claims 4
- 102100024341 10 kDa heat shock protein, mitochondrial Human genes 0.000 claims 3
- 102100026357 40S ribosomal protein S13 Human genes 0.000 claims 3
- 102100023541 Glutathione S-transferase omega-1 Human genes 0.000 claims 3
- 101000980303 Homo sapiens 10 kDa heat shock protein, mitochondrial Proteins 0.000 claims 3
- 101000718313 Homo sapiens 40S ribosomal protein S13 Proteins 0.000 claims 3
- 101000906386 Homo sapiens Glutathione S-transferase omega-1 Proteins 0.000 claims 3
- 101001098824 Homo sapiens Protein disulfide-isomerase A4 Proteins 0.000 claims 3
- 102100037089 Protein disulfide-isomerase A4 Human genes 0.000 claims 3
- 239000003446 ligand Substances 0.000 claims 3
- 102100025514 ATP-dependent 6-phosphofructokinase, platelet type Human genes 0.000 claims 2
- 101710106492 Acyl-CoA-binding protein Proteins 0.000 claims 2
- 101710169323 Acyl-CoA-binding protein homolog Proteins 0.000 claims 2
- 102100030291 Cornifin-B Human genes 0.000 claims 2
- 102100033325 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 Human genes 0.000 claims 2
- 102100031000 Hepatoma-derived growth factor Human genes 0.000 claims 2
- 101000693765 Homo sapiens ATP-dependent 6-phosphofructokinase, platelet type Proteins 0.000 claims 2
- 101000702152 Homo sapiens Cornifin-B Proteins 0.000 claims 2
- 101000926793 Homo sapiens Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 Proteins 0.000 claims 2
- 101001090050 Homo sapiens Thioredoxin-dependent peroxide reductase, mitochondrial Proteins 0.000 claims 2
- 101000795292 Homo sapiens Tripartite motif-containing protein 6 Proteins 0.000 claims 2
- 102100031269 Putative peripheral benzodiazepine receptor-related protein Human genes 0.000 claims 2
- 101000805921 Strongylocentrotus purpuratus Upstream stimulatory factor Proteins 0.000 claims 2
- 102100034769 Thioredoxin-dependent peroxide reductase, mitochondrial Human genes 0.000 claims 2
- 102100029673 Tripartite motif-containing protein 6 Human genes 0.000 claims 2
- 101000671634 Xenopus borealis Upstream stimulatory factor 1 Proteins 0.000 claims 2
- 239000002537 cosmetic Substances 0.000 claims 2
- 108010052188 hepatoma-derived growth factor Proteins 0.000 claims 2
- 210000002510 keratinocyte Anatomy 0.000 claims 2
- 102100036846 C-C motif chemokine 21 Human genes 0.000 claims 1
- 101000713085 Homo sapiens C-C motif chemokine 21 Proteins 0.000 claims 1
- 101000589870 Homo sapiens Prostaglandin reductase 3 Proteins 0.000 claims 1
- 101000635777 Homo sapiens Receptor-transporting protein 4 Proteins 0.000 claims 1
- 101150036282 Pfdn2 gene Proteins 0.000 claims 1
- 102100032255 Prostaglandin reductase 3 Human genes 0.000 claims 1
- 102100030854 Receptor-transporting protein 4 Human genes 0.000 claims 1
- 101100243555 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GIM4 gene Proteins 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6881—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from skin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6804—Nucleic acid analysis using immunogens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5023—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16306561 | 2016-11-25 | ||
| EP16306561.8 | 2016-11-25 | ||
| PCT/EP2017/080414 WO2018096117A1 (en) | 2016-11-25 | 2017-11-24 | New biomarkers of human skin aging |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2019116069A true RU2019116069A (ru) | 2020-12-25 |
Family
ID=57517827
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2019116069A RU2019116069A (ru) | 2016-11-25 | 2017-11-24 | Новые биомаркеры старения кожи человека |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20210109111A1 (OSRAM) |
| EP (1) | EP3545301A1 (OSRAM) |
| JP (1) | JP7115756B2 (OSRAM) |
| CN (1) | CN110268263B (OSRAM) |
| CA (1) | CA3041959A1 (OSRAM) |
| RU (1) | RU2019116069A (OSRAM) |
| WO (1) | WO2018096117A1 (OSRAM) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR112020024715A2 (pt) * | 2018-06-04 | 2021-03-23 | Avon Products. Inc. | biomarcadores proteicos para identificar e tratar o envelhecimento da pele e afecções cutâneas |
| JP7633003B2 (ja) * | 2019-11-29 | 2025-02-19 | ポーラ化成工業株式会社 | 抗老化成分のスクリーニング方法 |
| WO2023090901A1 (ko) * | 2021-11-18 | 2023-05-25 | 의료법인 성광의료재단 | 기계 학습을 이용한 세포 노화의 마커를 선별하는 방법, 세포 노화 바이오 마커, 및 이를 이용한 세놀리틱 제제를 스크리닝 하는 방법 |
| WO2023133240A1 (en) * | 2022-01-07 | 2023-07-13 | Revela, Inc. | Compositions, formulations, and methods for skin treatment |
| JP2023130972A (ja) * | 2022-03-08 | 2023-09-21 | 株式会社 資生堂 | 黄ぐすみ抑制方法、黄ぐすみ抑制剤のスクリーニング方法、及び黄ぐすみ感受性の評価方法 |
| CN121208353A (zh) * | 2025-08-22 | 2025-12-26 | 北京大学第一医院(北京大学第一临床医学院) | 一种辅助诊断pcos自发性早产的蛋白质生物标志物及其应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001068804A2 (en) * | 2000-03-10 | 2001-09-20 | Lifespan Biosciences, Inc. | Nucleic acid sequences associated with aging, particularly skin aging |
| DE10100121A1 (de) * | 2001-01-03 | 2002-08-01 | Henkel Kgaa | Verfahren zur Bestimmung des Hautstreß oder der Hautalterung in vitro |
| WO2004061456A2 (de) * | 2003-01-03 | 2004-07-22 | Alcedo Biotech Gmbh | Verwendungen von hmgb, hmgn, hmga proteinen |
| WO2004083398A2 (en) * | 2003-03-17 | 2004-09-30 | The Government Of The United States Of America As Represented By The Secretary Of Department Of Health And Human Services | Therapeutic uses of hmgn1 and hmgn2 |
| US7972788B2 (en) * | 2005-08-23 | 2011-07-05 | Fancl Corporation | Skin aging marker and technique for use thereof |
| US8859021B2 (en) * | 2007-05-14 | 2014-10-14 | Sytheon | Skin appearance through gene manipulation |
| KR100999261B1 (ko) * | 2007-10-09 | 2010-12-07 | (주)아모레퍼시픽 | 여성호르몬 결핍으로 초래되는 여성 피부의 노화 억제제 스크리닝 방법 |
| FR2925313A1 (fr) * | 2007-12-19 | 2009-06-26 | Oreal | Utilisation cosmetique de proteines de type plakoglobine |
| US20120034613A1 (en) * | 2010-08-03 | 2012-02-09 | Nse Products, Inc. | Apparatus and Method for Testing Relationships Between Gene Expression and Physical Appearance of Skin |
| EP2704728A4 (en) * | 2011-05-03 | 2015-04-22 | Dermachip Inc | EXPRESSION SIGNATURES OF AGENTS ASSOCIATED WITH SKIN AGING AND GEN NETWORKS |
| MX2015012298A (es) * | 2013-03-15 | 2015-12-16 | Procter & Gamble | Un metodo no invasivo para medir peptidos antimicrobianos de la piel como una medicion objetica de proteccion natural de los microbios. |
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2017
- 2017-11-24 CN CN201780072821.8A patent/CN110268263B/zh not_active Expired - Fee Related
- 2017-11-24 RU RU2019116069A patent/RU2019116069A/ru not_active Application Discontinuation
- 2017-11-24 WO PCT/EP2017/080414 patent/WO2018096117A1/en not_active Ceased
- 2017-11-24 EP EP17801484.1A patent/EP3545301A1/en not_active Withdrawn
- 2017-11-24 CA CA3041959A patent/CA3041959A1/en active Pending
- 2017-11-24 US US16/464,517 patent/US20210109111A1/en not_active Abandoned
- 2017-11-24 JP JP2019528092A patent/JP7115756B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN110268263B (zh) | 2022-07-19 |
| EP3545301A1 (en) | 2019-10-02 |
| WO2018096117A1 (en) | 2018-05-31 |
| JP2020502498A (ja) | 2020-01-23 |
| US20210109111A1 (en) | 2021-04-15 |
| JP7115756B2 (ja) | 2022-08-09 |
| CN110268263A (zh) | 2019-09-20 |
| CA3041959A1 (en) | 2018-05-31 |
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