MX2015012298A - Un metodo no invasivo para medir peptidos antimicrobianos de la piel como una medicion objetica de proteccion natural de los microbios. - Google Patents

Un metodo no invasivo para medir peptidos antimicrobianos de la piel como una medicion objetica de proteccion natural de los microbios.

Info

Publication number
MX2015012298A
MX2015012298A MX2015012298A MX2015012298A MX2015012298A MX 2015012298 A MX2015012298 A MX 2015012298A MX 2015012298 A MX2015012298 A MX 2015012298A MX 2015012298 A MX2015012298 A MX 2015012298A MX 2015012298 A MX2015012298 A MX 2015012298A
Authority
MX
Mexico
Prior art keywords
skin
defensin
protein
histone
noninvasive method
Prior art date
Application number
MX2015012298A
Other languages
English (en)
Inventor
Kevin John Mills
Kathleen Marie Kerr
Angela Marie Fieno
Yiping Sun
Tanuja Chaudhary
Raymond Alan Grant
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of MX2015012298A publication Critical patent/MX2015012298A/es

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6881—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Cosmetics (AREA)

Abstract

Un método no invasivo para medir la salud cutánea en un sujeto que comprende recolectar una muestra de células epiteliales ¡células cutáneas del sujeto; la detección de un nivel de uno o más biomarcadores de péptidos antimicrobianos en muestras de células epiteliales ¡células cutáneas; diagnosticar al sujeto como si tuviese un mecanismo de defensa debido al ataque microbiano en la piel o una medida del sistema que está en equilibrio con la homeostasis ambiental con base en el nivel de uno o más biomarcadores de péptidos antimicrobianos seleccionados del grupo que consiste en Histona H2B tipo 1-M, Histona H2A, Histona H4, Proteína S100-A7, Proteína S100- A8, Proteína S100-A9, Catepsina G, defensina de neutrófilo 3 (Defensina, alfa 3) (HNP3), Dermcidina, ribonucleasa- 7 -2 (nBDRibonucleasa. 7), beta defensina humana (-2) y Beta-defensina 103 (hBD-3) y enumerados en la Tabla 1, caracterizado porque las familias AMP incluyen proteína que incrementa la permiabilidad bactericida (BPI), Defensina, histona, toxina que forma poro, S100 proteína, Citotoxina, serma proteasa S1, Dual oxidasa, regulación de transcripción y mezclas de estos. Adicionalmente, un método no invasivo para evaluar la eficacia de productos para la salud de la piel.
MX2015012298A 2013-03-15 2014-03-14 Un metodo no invasivo para medir peptidos antimicrobianos de la piel como una medicion objetica de proteccion natural de los microbios. MX2015012298A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361794014P 2013-03-15 2013-03-15
PCT/US2014/028631 WO2014144289A2 (en) 2013-03-15 2014-03-14 A noninvasive method for measuring antimicrobial peptides from skin as an objective measurement of natural protection from microbes

Publications (1)

Publication Number Publication Date
MX2015012298A true MX2015012298A (es) 2015-12-16

Family

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Family Applications (1)

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MX2015012298A MX2015012298A (es) 2013-03-15 2014-03-14 Un metodo no invasivo para medir peptidos antimicrobianos de la piel como una medicion objetica de proteccion natural de los microbios.

Country Status (6)

Country Link
US (1) US20140273065A1 (es)
EP (3) EP3287782B1 (es)
JP (1) JP6336565B2 (es)
CN (1) CN105026930B (es)
MX (1) MX2015012298A (es)
WO (1) WO2014144289A2 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2015012298A (es) 2013-03-15 2015-12-16 Procter & Gamble Un metodo no invasivo para medir peptidos antimicrobianos de la piel como una medicion objetica de proteccion natural de los microbios.
CN108770366A (zh) * 2015-12-15 2018-11-06 凯斯西储大学 β防御素在上皮性癌评估中的应用
US20210109111A1 (en) * 2016-11-25 2021-04-15 Université Grenoble Alpes New biomarkers of human skin aging
JP7024003B2 (ja) * 2020-03-27 2022-02-22 株式会社ナリス化粧品 角層の水分保持能評価方法
EP4144862A1 (en) 2020-05-01 2023-03-08 Kao Corporation Method for detecting atopic dermatitis
RU2766346C1 (ru) * 2021-04-05 2022-03-15 федеральное государственное автономное образовательное учреждение высшего образования "Пермский национальный исследовательский политехнический университет" Способ определения противомикробной активности пептидов
CN115011712B (zh) * 2022-06-10 2023-03-10 南方海洋科学与工程广东省实验室(湛江) 一种哈维氏弧菌感染的生物标志物

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4835148A (en) * 1986-02-24 1989-05-30 The Procter & Gamble Co. Shampoo compositions comprising water-insoluble particulate anti-inflammatory agents
US5976832A (en) * 1995-03-06 1999-11-02 Tonen Corporation DNA encoding novel calcium-binding proteins
JP4001383B2 (ja) * 1995-12-16 2007-10-31 プラントン・ゲゼルシヤフト・ミット・ベシュレンクテル・ハフツング 細菌、菌類、およびウイルスに対して有効で、かつ脊椎動物性蛋白質を含む化粧用製剤
US6565854B2 (en) * 1998-08-13 2003-05-20 Philadelphia Health And Education Corporation Antimicrobial histone H1 compositions, kits, and methods of use thereof
CA2408253A1 (en) * 2000-05-09 2001-11-15 Genetics Institute, Llc Compositions, kits, and methods for identification, assessment, prevention, and therapy of psoriasis
SE0102864D0 (sv) * 2001-08-29 2001-08-29 Svenska Miljoebolaget Svv Ab Antimicrorobial agent
JP3863462B2 (ja) * 2002-06-24 2006-12-27 株式会社資生堂 皮膚疾患および敏感肌の検査方法ならびにその方法に利用するキット
IL153557A0 (en) * 2002-12-19 2003-07-06 Yitzchak Hillman Antibodies and antagonists to antimicrobial peptides for the purpose of treating, inhibiting and preventing auto immune diseases
NZ540506A (en) * 2002-12-19 2008-09-26 Yitzchak Hillman Disease treatment via antimicrobial peptide inhibitors
US8068990B2 (en) * 2003-03-25 2011-11-29 Hologic, Inc. Diagnosis of intra-uterine infection by proteomic analysis of cervical-vaginal fluids
US7183057B2 (en) * 2004-03-31 2007-02-27 Dermtech International Tape stripping methods for analysis of skin disease and pathological skin state
DE102005014687A1 (de) * 2005-03-29 2006-10-12 Henkel Kgaa Zusammensetzung enthaltend ß-Defensin 2
RU2491052C2 (ru) * 2007-12-21 2013-08-27 Басф Се Противоперхотные композиции, содержащие пептиды
ES2324192B1 (es) * 2008-01-30 2010-06-17 PUIG BEAUTY & FASHION GROUP, S.L. Derivados peptidicos utiles en el tratamiento, cuidado o limpieza de la piel, mucosa, cuero cabelludo o uñas.
KR20110074857A (ko) * 2008-10-02 2011-07-04 바이엘 컨수머 케어 악티엔게젤샤프트 증강된 항미생물 펩티드 및 단백질 수준과 관련된 피부 질환 또는 장애를 치료 또는 완화하기 위한 조성물
FR2948021A1 (fr) * 2009-07-16 2011-01-21 Oreal Utilisation cosmetique de polypeptides de type lacritine
US8420054B2 (en) * 2009-09-18 2013-04-16 The Procter & Gamble Company Noninvasive method for measuring histamine from skin as an objective measurement of itch
JP5488885B2 (ja) * 2009-10-28 2014-05-14 国立大学法人 東京大学 感染症の疾患マーカー
JP2011168555A (ja) * 2010-02-22 2011-09-01 Pola Chemical Industries Inc 鑑別方法
US20120329760A1 (en) * 2011-04-19 2012-12-27 Nationwide Children's Hospital, Inc. Rnase 7 as a marker for infection
MX2015012298A (es) 2013-03-15 2015-12-16 Procter & Gamble Un metodo no invasivo para medir peptidos antimicrobianos de la piel como una medicion objetica de proteccion natural de los microbios.

Also Published As

Publication number Publication date
US20140273065A1 (en) 2014-09-18
WO2014144289A3 (en) 2015-03-05
EP3287782B1 (en) 2020-04-22
CN105026930B (zh) 2018-06-12
JP2016513808A (ja) 2016-05-16
EP2972328B1 (en) 2019-06-26
WO2014144289A2 (en) 2014-09-18
CN105026930A (zh) 2015-11-04
JP6336565B2 (ja) 2018-06-06
EP3287781B1 (en) 2024-04-17
EP3287782A1 (en) 2018-02-28
EP2972328A2 (en) 2016-01-20
EP3287781A1 (en) 2018-02-28

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