RU2018107055A - Фармацевтическая композиция с улучшенной устойчивостью при хранении и способ ее получения - Google Patents

Фармацевтическая композиция с улучшенной устойчивостью при хранении и способ ее получения Download PDF

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Publication number
RU2018107055A
RU2018107055A RU2018107055A RU2018107055A RU2018107055A RU 2018107055 A RU2018107055 A RU 2018107055A RU 2018107055 A RU2018107055 A RU 2018107055A RU 2018107055 A RU2018107055 A RU 2018107055A RU 2018107055 A RU2018107055 A RU 2018107055A
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RU
Russia
Prior art keywords
pharmaceutical composition
composition according
formula
mass parts
amount
Prior art date
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RU2018107055A
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English (en)
Russian (ru)
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RU2018107055A3 (ja
Inventor
Бонг Ох КИМ
Киу Дзин КИУНГ
Дзи Йеонг КИМ
Хие Рим КИМ
Бум Чан МИН
Йоо Дзеонг ЙООН
Мин Хио СЕО
Йил Воонг ЙИ
Original Assignee
Самьянг Байофармасьютикалз Корпорейшн
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Publication of RU2018107055A3 publication Critical patent/RU2018107055A3/ru
Publication of RU2018107055A publication Critical patent/RU2018107055A/ru

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • A61K31/122Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
RU2018107055A 2015-07-28 2016-07-28 Фармацевтическая композиция с улучшенной устойчивостью при хранении и способ ее получения RU2018107055A (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20150106629 2015-07-28
KR10-2015-0106629 2015-07-28
PCT/KR2016/008270 WO2017018820A1 (en) 2015-07-28 2016-07-28 Pharmaceutical composition with improved storage stability and method for preparing the same

Publications (2)

Publication Number Publication Date
RU2018107055A3 RU2018107055A3 (ja) 2019-08-28
RU2018107055A true RU2018107055A (ru) 2019-08-28

Family

ID=57884713

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2018107055A RU2018107055A (ru) 2015-07-28 2016-07-28 Фармацевтическая композиция с улучшенной устойчивостью при хранении и способ ее получения

Country Status (13)

Country Link
EP (1) EP3328437A4 (ja)
JP (1) JP2018521105A (ja)
KR (1) KR101787453B1 (ja)
CN (1) CN107466231A (ja)
AU (1) AU2016299548A1 (ja)
BR (1) BR112018001737A2 (ja)
CA (1) CA2993928A1 (ja)
HK (1) HK1249441A1 (ja)
IL (1) IL257187A (ja)
MX (1) MX2018001223A (ja)
RU (1) RU2018107055A (ja)
WO (1) WO2017018820A1 (ja)
ZA (1) ZA201801187B (ja)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6020507A (en) 1998-03-02 2000-02-01 Bristol-Myers Squibb Company Synthesis of paclitaxel from baccatin III by protection of the 7-hydroxyl of baccatin III using a strong base and an electrophile
JP4049588B2 (ja) * 2000-05-12 2008-02-20 サムヤン コーポレイション ブロック共重合体の相分離による高分子ミセルの製造方法
US7217770B2 (en) * 2000-05-17 2007-05-15 Samyang Corporation Stable polymeric micelle-type drug composition and method for the preparation thereof
ES2292827T3 (es) * 2001-10-18 2008-03-16 Samyang Corporation Composicion micelar polimerica con estabilidad mejorada.
WO2005037840A1 (en) 2003-10-16 2005-04-28 Mayne Pharma (Usa), Inc. Method for inverting the c2’ hydroxyl group of taxane esters
US9801818B2 (en) * 2007-12-31 2017-10-31 Samyang Biopharmaceuticals Corporation Method for stabilizing amphiphilic block copolymer micelle composition containing poorly water-soluble drug
KR101024742B1 (ko) * 2007-12-31 2011-03-24 주식회사 삼양사 탁산 함유 양친성 블록 공중합체 미셀 조성물 및 그 제조방법
WO2009091150A2 (en) * 2007-12-31 2009-07-23 Samyang Corporation Highly pure amphiphilic copolymer comprising hydrophobic block from alpha-hydroxy acid and process for the preparation thereof
EP2201935B1 (en) * 2008-12-26 2020-07-08 Samyang Biopharmaceuticals Corporation Polymeric micelle composition containing a poorly soluble drug and preparation method of the same

Also Published As

Publication number Publication date
IL257187A (en) 2018-03-29
CN107466231A (zh) 2017-12-12
HK1249441A1 (zh) 2018-11-02
AU2016299548A1 (en) 2018-02-22
EP3328437A4 (en) 2019-03-20
MX2018001223A (es) 2018-11-09
JP2018521105A (ja) 2018-08-02
EP3328437A1 (en) 2018-06-06
KR20170015200A (ko) 2017-02-08
BR112018001737A2 (pt) 2018-09-11
ZA201801187B (en) 2018-12-19
CA2993928A1 (en) 2017-02-02
KR101787453B1 (ko) 2017-10-19
RU2018107055A3 (ja) 2019-08-28
WO2017018820A1 (en) 2017-02-02

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