RU2017116973A - Способы применения и композиции нейрегулинов для предотвращения, лечения или замедления сердечной недостаточности с сохраненной фракцией выброса - Google Patents

Способы применения и композиции нейрегулинов для предотвращения, лечения или замедления сердечной недостаточности с сохраненной фракцией выброса Download PDF

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Publication number
RU2017116973A
RU2017116973A RU2017116973A RU2017116973A RU2017116973A RU 2017116973 A RU2017116973 A RU 2017116973A RU 2017116973 A RU2017116973 A RU 2017116973A RU 2017116973 A RU2017116973 A RU 2017116973A RU 2017116973 A RU2017116973 A RU 2017116973A
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Prior art keywords
heart failure
pharmaceutical preparation
mammal
neuregulin
composition
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RU2017116973A
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Russian (ru)
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RU2017116973A3 (https=
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Миндун ЧЖОУ
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Цзэньсунь (Шанхай) Сайенс Энд Текнолоджи Лимитед
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Publication of RU2017116973A publication Critical patent/RU2017116973A/ru
Publication of RU2017116973A3 publication Critical patent/RU2017116973A3/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1883—Neuregulins, e.g.. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
RU2017116973A 2014-10-17 2015-10-08 Способы применения и композиции нейрегулинов для предотвращения, лечения или замедления сердечной недостаточности с сохраненной фракцией выброса RU2017116973A (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201410550212.7A CN105561298A (zh) 2014-10-17 2014-10-17 神经调节蛋白用于预防、治疗或延迟射血分数保留的心力衰竭的方法和组合物
CN201410550212.7 2014-10-17
PCT/CN2015/091459 WO2016058493A1 (zh) 2014-10-17 2015-10-08 神经调节蛋白用于预防、治疗或延迟射血分数保留的心力衰竭的方法和组合物

Publications (2)

Publication Number Publication Date
RU2017116973A true RU2017116973A (ru) 2018-11-19
RU2017116973A3 RU2017116973A3 (https=) 2019-05-06

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RU2017116973A RU2017116973A (ru) 2014-10-17 2015-10-08 Способы применения и композиции нейрегулинов для предотвращения, лечения или замедления сердечной недостаточности с сохраненной фракцией выброса

Country Status (10)

Country Link
US (3) US10561709B2 (https=)
EP (2) EP4112068A1 (https=)
JP (4) JP2017532343A (https=)
KR (2) KR20230159650A (https=)
CN (3) CN105561298A (https=)
AU (2) AU2015333335B2 (https=)
CA (1) CA2963322A1 (https=)
ES (1) ES2924395T3 (https=)
RU (1) RU2017116973A (https=)
WO (1) WO2016058493A1 (https=)

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Publication number Publication date
EP3207940A1 (en) 2017-08-23
EP3207940A4 (en) 2018-06-06
JP2017532343A (ja) 2017-11-02
AU2021258063B2 (en) 2025-02-27
ES2924395T3 (es) 2022-10-06
CN111407882A (zh) 2020-07-14
AU2021258063A1 (en) 2021-11-25
CA2963322A1 (en) 2016-04-21
CN108064164A (zh) 2018-05-22
KR20230159650A (ko) 2023-11-21
CN105561298A (zh) 2016-05-11
US20200368317A1 (en) 2020-11-26
WO2016058493A1 (zh) 2016-04-21
JP2024164068A (ja) 2024-11-26
US10561709B2 (en) 2020-02-18
US20170232068A1 (en) 2017-08-17
AU2015333335B2 (en) 2021-08-05
KR102603711B1 (ko) 2023-11-20
EP3207940B1 (en) 2022-06-01
RU2017116973A3 (https=) 2019-05-06
AU2015333335A1 (en) 2017-04-20
US20220354928A1 (en) 2022-11-10
KR20170066440A (ko) 2017-06-14
EP4112068A1 (en) 2023-01-04
JP2020193217A (ja) 2020-12-03
JP2022153417A (ja) 2022-10-12

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