RU2017112308A3 - - Google Patents

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Publication number
RU2017112308A3
RU2017112308A3 RU2017112308A RU2017112308A RU2017112308A3 RU 2017112308 A3 RU2017112308 A3 RU 2017112308A3 RU 2017112308 A RU2017112308 A RU 2017112308A RU 2017112308 A RU2017112308 A RU 2017112308A RU 2017112308 A3 RU2017112308 A3 RU 2017112308A3
Authority
RU
Russia
Application number
RU2017112308A
Other languages
Russian (ru)
Other versions
RU2703297C2 (ru
RU2017112308A (ru
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of RU2017112308A publication Critical patent/RU2017112308A/ru
Publication of RU2017112308A3 publication Critical patent/RU2017112308A3/ru
Application granted granted Critical
Publication of RU2703297C2 publication Critical patent/RU2703297C2/ru

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Anesthesiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Inorganic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
RU2017112308A 2014-10-23 2015-10-21 Композиции и способы для лечения бессонницы RU2703297C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462067443P 2014-10-23 2014-10-23
US62/067,443 2014-10-23
PCT/JP2015/080304 WO2016063995A1 (en) 2014-10-23 2015-10-21 Compositions and methods for treating insomnia

Publications (3)

Publication Number Publication Date
RU2017112308A RU2017112308A (ru) 2018-11-26
RU2017112308A3 true RU2017112308A3 (OSRAM) 2019-05-08
RU2703297C2 RU2703297C2 (ru) 2019-10-16

Family

ID=55761025

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2017112308A RU2703297C2 (ru) 2014-10-23 2015-10-21 Композиции и способы для лечения бессонницы

Country Status (14)

Country Link
US (3) US10188652B2 (OSRAM)
EP (1) EP3209298B1 (OSRAM)
JP (1) JP6659681B2 (OSRAM)
KR (1) KR102444608B1 (OSRAM)
CN (1) CN107810006B (OSRAM)
AU (1) AU2015336463B2 (OSRAM)
BR (1) BR112017007063A2 (OSRAM)
CA (1) CA2964504C (OSRAM)
ES (1) ES2843952T3 (OSRAM)
IL (1) IL251759B (OSRAM)
MX (1) MX376164B (OSRAM)
RU (1) RU2703297C2 (OSRAM)
SG (2) SG10202007759RA (OSRAM)
WO (1) WO2016063995A1 (OSRAM)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2964504C (en) 2014-10-23 2022-08-23 Eisai R&D Management Co., Ltd. Oral dosage form comprising a cyclopropanecarboxamide derivative for use in treating insomnia
CA3022068A1 (en) * 2016-05-12 2017-11-16 Eisai R&D Management Co., Ltd. Methods of treating circadian rhythm sleep disorders
CN116172869A (zh) * 2016-08-10 2023-05-30 豪夫迈·罗氏有限公司 包含Akt蛋白激酶抑制剂的药物组合物
JP7179049B2 (ja) * 2017-08-01 2022-11-28 ベルゲン ファーマシューティカル、 エルエルシー オレキシン受容体拮抗薬の結晶形及びその製造方法並びに用途
CN113660934A (zh) 2018-11-21 2021-11-16 特默罗制药股份有限公司 罗非昔布的纯化形式、制备方法和用途
WO2020263253A1 (en) * 2019-06-26 2020-12-30 Moline Margaret Lemborexant for treating sleep issues
JP2022538170A (ja) * 2019-06-26 2022-08-31 エーザイ・アール・アンド・ディー・マネジメント株式会社 睡眠問題の治療のためのレンボレキサント
AU2020307991A1 (en) * 2019-06-26 2022-02-10 Eisai R&D Management Co., Ltd. Lemborexant for treating sleep issues
CN114980892A (zh) * 2019-09-13 2022-08-30 武田药品工业株式会社 用于治疗发作性睡病的tak-925
CN114502167A (zh) * 2019-09-13 2022-05-13 卫材R&D管理有限公司 用于治疗失眠的药物组合物
AU2020408557A1 (en) 2019-12-20 2022-08-11 Eisai R&D Management Co., Ltd. Use of lemborexant for treating insomnia
KR20220129538A (ko) 2020-01-16 2022-09-23 에자이 알앤드디 매니지먼트 가부시키가이샤 렘보렉산트의 약물 물질 및 이를 포함하는 의약 조성물
PH12022552763A1 (en) 2020-04-19 2024-03-25 Idorsia Pharmaceuticals Ltd Medical use of daridorexant
CN111450076A (zh) * 2020-05-25 2020-07-28 安徽省逸欣铭医药科技有限公司 一种Lemborexant软胶囊组合物及其制备方法
TW202425995A (zh) 2022-09-23 2024-07-01 日商衛材R&D企管股份有限公司 減少與神經退化疾病相關的神經退化的方法

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JPH06328057A (ja) 1993-05-26 1994-11-29 Sanyo Electric Co Ltd 厨芥処理装置
CA2220036A1 (en) 1995-05-05 1996-11-07 Human Genome Sciences, Inc. Human neuropeptide receptor
US6001963A (en) 1996-12-17 1999-12-14 Smithkline Beecham Corporation Ligands of the neuropeptide receptor HFGAN72
US6309854B1 (en) 1996-12-17 2001-10-30 Smithkline Beecham Corporation Polynucleotides encoding ligands of the neuropeptide receptor HFGAN72
US6020157A (en) 1997-04-30 2000-02-01 Smithkline Beecham Corporation Polynucleotides encoding HFGAN72X receptor
US5935814A (en) 1997-04-30 1999-08-10 Smithkline Beecham Corporation Polynucleotides encoding HFGAN72Y receptor
US6166193A (en) 1997-07-25 2000-12-26 Board Of Regents, University Of Texas System Polynucleotides encoding MY1 receptor
BRPI0508263B8 (pt) 2004-03-01 2021-05-25 Idorsia Pharmaceuticals Ltd derivados de 1, 2, 3, 4-tetra-hidro-isoquinolina, composição farmacêutica, e, uso de derivado de 1, 2, 3, 4-tetra-hidro-isoquinolina
BRPI0515571A (pt) 2004-09-23 2008-07-29 Pfizer Prod Inc agonistas de receptor de trombopoetina
JP2006328057A (ja) 2005-04-25 2006-12-07 Eisai R & D Management Co Ltd 抗不安薬及びそのスクリーニング方法
JP4582722B2 (ja) 2006-03-15 2010-11-17 アクテリオン ファーマシューティカルズ リミテッド 記憶機能を向上させるテトラヒドロイソキノリン誘導体
WO2007129188A1 (en) 2006-05-10 2007-11-15 Pfizer Japan Inc. Cyclopropanecarboxamide compound
EA200970266A1 (ru) 2006-09-11 2009-08-28 Глэксо Груп Лимитед Азабициклические соединения в качестве ингибиторов повторного поглощения моноаминов
WO2008038251A2 (en) 2006-09-29 2008-04-03 Actelion Pharmaceuticals Ltd 3-aza-bicyclo[3.1.0]hexane derivatives
PE20081229A1 (es) 2006-12-01 2008-08-28 Merck & Co Inc Antagonistas de receptor de orexina de diazepam sustituido
CL2007003827A1 (es) 2006-12-28 2008-09-26 Actelion Pharmaceuticals Ltd Compuestos derivados de n-(2-aza-biciclo(3.1.0)hex-3-ilmetil)amida; y su uso para prevenir o tratar la depresion, neurosis, esquizofrenia, ansiedad, adicciones, epilepsia, dolor, enfermedades cardiacas, entre otras.
BRPI0817198A2 (pt) 2007-09-21 2015-03-17 Sanofi Aventis (ciclopropilfenil)feniloxalamidas, método para a produção das mesmas, e uso das mesmas como um medicamento
PE20091010A1 (es) 2007-10-10 2009-08-08 Actelion Pharmaceuticals Ltd Derivados de tetrahidroquinolina
EP2537282B1 (en) * 2010-02-15 2015-09-16 Koninklijke Philips N.V. Mitigation of control channel interference
SI2626350T1 (sl) * 2010-09-22 2015-09-30 Eisai R&D Management Co., Ltd. Spojina ciklopropana
US20120165339A1 (en) 2010-12-22 2012-06-28 Eisai R&D Management Co., Ltd. Cyclopropane derivatives
CA2964504C (en) 2014-10-23 2022-08-23 Eisai R&D Management Co., Ltd. Oral dosage form comprising a cyclopropanecarboxamide derivative for use in treating insomnia

Also Published As

Publication number Publication date
RU2703297C2 (ru) 2019-10-16
BR112017007063A2 (pt) 2018-02-14
EP3209298A1 (en) 2017-08-30
KR20170068478A (ko) 2017-06-19
CA2964504C (en) 2022-08-23
KR102444608B1 (ko) 2022-09-20
EP3209298B1 (en) 2020-12-02
IL251759A0 (en) 2017-06-29
IL251759B (en) 2021-01-31
AU2015336463B2 (en) 2020-06-18
MX2017004950A (es) 2018-01-16
JP6659681B2 (ja) 2020-03-04
AU2015336463A1 (en) 2017-05-04
CA2964504A1 (en) 2016-04-28
US10188652B2 (en) 2019-01-29
US10702529B2 (en) 2020-07-07
MX376164B (es) 2025-03-07
EP3209298A4 (en) 2018-06-20
US20200268754A1 (en) 2020-08-27
US20170252342A1 (en) 2017-09-07
ES2843952T3 (es) 2021-07-21
RU2017112308A (ru) 2018-11-26
WO2016063995A1 (en) 2016-04-28
SG11201703064WA (en) 2017-05-30
JP2017531683A (ja) 2017-10-26
US11026944B2 (en) 2021-06-08
SG10202007759RA (en) 2020-09-29
CN107810006B (zh) 2021-03-30
CN107810006A (zh) 2018-03-16
US20190201399A1 (en) 2019-07-04

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