RU2016137789A3 - - Google Patents
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- Publication number
- RU2016137789A3 RU2016137789A3 RU2016137789A RU2016137789A RU2016137789A3 RU 2016137789 A3 RU2016137789 A3 RU 2016137789A3 RU 2016137789 A RU2016137789 A RU 2016137789A RU 2016137789 A RU2016137789 A RU 2016137789A RU 2016137789 A3 RU2016137789 A3 RU 2016137789A3
- Authority
- RU
- Russia
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1403536.4 | 2014-02-28 | ||
| GBGB1403536.4A GB201403536D0 (en) | 2014-02-28 | 2014-02-28 | Inhibitor compounds |
| PCT/GB2015/050590 WO2015128676A1 (en) | 2014-02-28 | 2015-02-27 | N2-phenyl-pyrido[3,4-d]pyrimidine-2,8-diamine derivatives and their use as mps1 inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| RU2016137789A RU2016137789A (ru) | 2018-04-03 |
| RU2016137789A3 true RU2016137789A3 (ru) | 2018-10-23 |
| RU2693460C2 RU2693460C2 (ru) | 2019-07-03 |
Family
ID=50490546
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2016137789A RU2693460C2 (ru) | 2014-02-28 | 2015-02-27 | ПРОИЗВОДНЫЕ N2-(2-ФЕНИЛ)-ПИРИДО[3,4-d]ПИРИМИДИН-2,8-ДИАМИНА И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ MPS1 ИНГИБИТОРА |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US9902721B2 (ru) |
| EP (2) | EP3575299B1 (ru) |
| JP (1) | JP6440728B2 (ru) |
| CN (1) | CN106459035B (ru) |
| AU (1) | AU2015221956B2 (ru) |
| BR (1) | BR112016019733B1 (ru) |
| CA (1) | CA2939058C (ru) |
| ES (2) | ES2926641T3 (ru) |
| GB (1) | GB201403536D0 (ru) |
| RU (1) | RU2693460C2 (ru) |
| WO (1) | WO2015128676A1 (ru) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201216017D0 (en) | 2012-09-07 | 2012-10-24 | Cancer Rec Tech Ltd | Inhibitor compounds |
| GB201403536D0 (en) * | 2014-02-28 | 2014-04-16 | Cancer Rec Tech Ltd | Inhibitor compounds |
| GB201522532D0 (en) * | 2015-12-21 | 2016-02-03 | Cancer Rec Tech Ltd | Novel pyrrolo[3,2-c]pyridine-6-amino derivatives |
| US11084814B2 (en) * | 2016-11-28 | 2021-08-10 | Teijin Pharma Limited | Pyrido[3, 4-d]pyrimidine derivative and pharmaceutically acceptable salt thereof |
| WO2018097295A1 (ja) * | 2016-11-28 | 2018-05-31 | 帝人ファーマ株式会社 | ピリド［３，４－ｄ］ピリミジン誘導体又はその溶媒和物の結晶 |
| GB201709840D0 (en) * | 2017-06-20 | 2017-08-02 | Inst Of Cancer Research: Royal Cancer Hospital | Methods and medical uses |
| WO2018234778A1 (en) * | 2017-06-20 | 2018-12-27 | The Institute Of Cancer Research: Royal Cancer Hospital | METHODS AND MEDICAL USES |
| GB201809460D0 (en) | 2018-06-08 | 2018-07-25 | Crt Pioneer Fund Lp | Salt form |
| GB201809458D0 (en) | 2018-06-08 | 2018-07-25 | Crt Pioneer Fund Lp | Salt form |
| KR20200110250A (ko) * | 2019-03-13 | 2020-09-23 | 보로노이바이오 주식회사 | 헤테로아릴 유도체 및 이를 유효성분으로 포함하는 약학적 조성물 |
| JP7236204B2 (ja) | 2019-06-28 | 2023-03-09 | ダイハツ工業株式会社 | コンソールボックス |
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| US3021332A (en) | 1954-01-04 | 1962-02-13 | Burroughs Wellcome Co | Pyrido (2, 3-d) pyrimidine compounds and method of making |
| ES2146782T3 (es) | 1994-11-14 | 2000-08-16 | Warner Lambert Co | 6-aril-pirido(2,3-d)pirimidinas y naftiridinas para la inhibicion de la proliferacion celular inducida por la proteina tirosina quinasa. |
| GB9624482D0 (en) | 1995-12-18 | 1997-01-15 | Zeneca Phaema S A | Chemical compounds |
| EP0880508B1 (en) | 1996-02-13 | 2003-04-16 | AstraZeneca AB | Quinazoline derivatives as vegf inhibitors |
| ATE211134T1 (de) | 1996-03-05 | 2002-01-15 | 4-anilinochinazolin derivate | |
| GB9718972D0 (en) | 1996-09-25 | 1997-11-12 | Zeneca Ltd | Chemical compounds |
| GB9714249D0 (en) | 1997-07-08 | 1997-09-10 | Angiogene Pharm Ltd | Vascular damaging agents |
| GB9900334D0 (en) | 1999-01-07 | 1999-02-24 | Angiogene Pharm Ltd | Tricylic vascular damaging agents |
| GB9900752D0 (en) | 1999-01-15 | 1999-03-03 | Angiogene Pharm Ltd | Benzimidazole vascular damaging agents |
| ATE482946T1 (de) | 1999-02-10 | 2010-10-15 | Astrazeneca Ab | Chinazolinderivate als angiogenesehemmer und zwischenprodukte dafür |
| US7053070B2 (en) | 2000-01-25 | 2006-05-30 | Warner-Lambert Company | Pyrido[2,3-d]pyrimidine-2,7-diamine kinase inhibitors |
| PL356802A1 (en) | 2000-01-25 | 2004-07-12 | Warner-Lambert Company | Pyrido[2,3-d]pyrimidine-2,7-diamine kinase inhibitors |
| US6653332B2 (en) | 2000-05-03 | 2003-11-25 | Tularik Inc. | Combination therapeutic compositions and method of use |
| KR20030013433A (ko) | 2000-05-31 | 2003-02-14 | 아스트라제네카 아베 | 혈관 손상 활성을 가진 인돌 유도체 |
| UA73993C2 (ru) | 2000-06-06 | 2005-10-17 | Астразенека Аб | Хиназолиновые производные для лечения опухолей и фармацевтическая композиция |
| AU6623301A (en) | 2000-07-07 | 2002-01-21 | Angiogene Pharm Ltd | Colchinol derivatives as vascular damaging agents |
| EE200300015A (et) | 2000-07-07 | 2004-10-15 | Angiogene Pharmaceuticals Limited | Kolhinooli derivaadid kui angiogeneesi inhibiitorid |
| WO2002090360A1 (en) | 2001-05-10 | 2002-11-14 | Smithkline Beecham Corporation | Compounds useful as kinase inhibitors for the treatment of hyperproliferative diseases |
| AU2002324450A1 (en) | 2001-06-21 | 2003-01-08 | Ariad Pharmaceuticals, Inc. | Novel pyridopyrimidines and uses thereof |
| US20030187026A1 (en) | 2001-12-13 | 2003-10-02 | Qun Li | Kinase inhibitors |
| EP1463505A2 (en) | 2001-12-13 | 2004-10-06 | Abbott Laboratories | 3-(phenyl-alkoxy)-5-(phenyl)-pyridine derivatives and related compounds as kinase inhibitors for the treatment of cancer |
| KR100714519B1 (ko) | 2002-03-07 | 2007-05-07 | 에프. 호프만-라 로슈 아게 | 이환 피리딘 및 피리미딘 ｐ38 키나아제 억제제 |
| MXPA05005116A (es) | 2002-11-12 | 2005-07-01 | Abbott Lab | Aminas biciclicas sustituidas en la forma de ligandos del receptor de histamina-3. |
| US20040092521A1 (en) | 2002-11-12 | 2004-05-13 | Altenbach Robert J. | Bicyclic-substituted amines as histamine-3 receptor ligands |
| MXPA05007503A (es) | 2003-01-17 | 2005-09-21 | Warner Lambert Co | Heterociclicos 2-aminopiridina sustituidos como inhibidores de proliferacion celular. |
| JP4189492B2 (ja) | 2004-03-22 | 2008-12-03 | 独立行政法人物質・材料研究機構 | 層状複水酸化物／ゼオライト複合体 |
| US20050256118A1 (en) | 2004-05-12 | 2005-11-17 | Altenbach Robert J | Bicyclic-substituted amines having cyclic-substituted monocyclic substituents |
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| AU2006264043B2 (en) | 2005-06-28 | 2012-04-26 | Sanofi-Aventis | Isoquinoline derivatives as inhibitors of Rho-kinase |
| AR060358A1 (es) * | 2006-04-06 | 2008-06-11 | Novartis Vaccines & Diagnostic | Quinazolinas para la inhibicion de pdk 1 |
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| TWI398252B (zh) | 2006-05-26 | 2013-06-11 | Novartis Ag | 吡咯并嘧啶化合物及其用途 |
| TW200808325A (en) | 2006-07-06 | 2008-02-16 | Astrazeneca Ab | Novel compounds |
| JP2010514693A (ja) | 2006-12-22 | 2010-05-06 | ノバルティス アーゲー | Ｐｄｋ１阻害のためのキナゾリン |
| WO2008135232A1 (en) | 2007-05-02 | 2008-11-13 | Riccardo Cortese | Use and compositions of purine derivatives for the treatment of proliferative disorders |
| EA201000341A1 (ru) * | 2007-08-23 | 2010-10-29 | Астразенека Аб | 2-анилинопурин-8-оны в качестве ингибиторов ttk/mps1 для лечения пролиферативных нарушений |
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| EP2630136A1 (en) | 2010-10-21 | 2013-08-28 | Universität des Saarlandes | Selective cyp11b1 inhibitors for the treatment of cortisol dependent diseases |
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| TWI450891B (zh) | 2010-12-29 | 2014-09-01 | Dev Center Biotechnology | 新穎微管蛋白抑制劑 |
| EP2668190B1 (en) * | 2011-01-26 | 2016-08-17 | Nerviano Medical Sciences S.r.l. | Tricyclic pyrrolo derivatives, process for their preparation and their use as kinase inhibitors |
| GB201104267D0 (en) * | 2011-03-14 | 2011-04-27 | Cancer Rec Tech Ltd | Pyrrolopyridineamino derivatives |
| US9745191B2 (en) | 2011-04-11 | 2017-08-29 | Saudi Arabian Oil Company | Auto thermal reforming (ATR) catalytic structures |
| GB201216018D0 (en) | 2012-09-07 | 2012-10-24 | Cancer Rec Tech Ltd | Pharmacologically active compounds |
| GB201216017D0 (en) | 2012-09-07 | 2012-10-24 | Cancer Rec Tech Ltd | Inhibitor compounds |
| JP5928960B2 (ja) | 2013-06-04 | 2016-06-01 | 国立大学法人佐賀大学 | イオン吸着材の製造方法 |
| GB201403536D0 (en) * | 2014-02-28 | 2014-04-16 | Cancer Rec Tech Ltd | Inhibitor compounds |
-
2014
- 2014-02-28 GB GBGB1403536.4A patent/GB201403536D0/en not_active Ceased
-
2015
- 2015-02-27 EP EP19173169.4A patent/EP3575299B1/en active Active
- 2015-02-27 ES ES19173169T patent/ES2926641T3/es active Active
- 2015-02-27 US US15/121,432 patent/US9902721B2/en active Active
- 2015-02-27 BR BR112016019733-0A patent/BR112016019733B1/pt active IP Right Grant
- 2015-02-27 EP EP15707759.5A patent/EP3110816B1/en active Active
- 2015-02-27 JP JP2016554566A patent/JP6440728B2/ja active Active
- 2015-02-27 WO PCT/GB2015/050590 patent/WO2015128676A1/en active Application Filing
- 2015-02-27 AU AU2015221956A patent/AU2015221956B2/en active Active
- 2015-02-27 RU RU2016137789A patent/RU2693460C2/ru active
- 2015-02-27 CA CA2939058A patent/CA2939058C/en active Active
- 2015-02-27 ES ES15707759T patent/ES2739148T3/es active Active
- 2015-02-27 CN CN201580010416.4A patent/CN106459035B/zh active Active
-
2018
- 2018-01-03 US US15/861,287 patent/US10399974B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20160362409A1 (en) | 2016-12-15 |
| AU2015221956B2 (en) | 2019-05-09 |
| US9902721B2 (en) | 2018-02-27 |
| RU2016137789A (ru) | 2018-04-03 |
| CN106459035A (zh) | 2017-02-22 |
| WO2015128676A1 (en) | 2015-09-03 |
| EP3575299A1 (en) | 2019-12-04 |
| EP3110816B1 (en) | 2019-06-19 |
| CA2939058A1 (en) | 2015-09-03 |
| BR112016019733B1 (pt) | 2022-12-20 |
| US10399974B2 (en) | 2019-09-03 |
| ES2926641T3 (es) | 2022-10-27 |
| CA2939058C (en) | 2022-04-26 |
| US20180194761A1 (en) | 2018-07-12 |
| RU2693460C2 (ru) | 2019-07-03 |
| BR112016019733A2 (ru) | 2017-08-15 |
| AU2015221956A1 (en) | 2016-07-07 |
| JP6440728B2 (ja) | 2018-12-19 |
| GB201403536D0 (en) | 2014-04-16 |
| EP3110816A1 (en) | 2017-01-04 |
| JP2017506661A (ja) | 2017-03-09 |
| ES2739148T3 (es) | 2020-01-29 |
| CN106459035B (zh) | 2018-04-06 |
| EP3575299B1 (en) | 2022-07-20 |