RU2016121723A - The method of obtaining nanocapsules AEKol - Google Patents

The method of obtaining nanocapsules AEKol Download PDF

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Publication number
RU2016121723A
RU2016121723A RU2016121723A RU2016121723A RU2016121723A RU 2016121723 A RU2016121723 A RU 2016121723A RU 2016121723 A RU2016121723 A RU 2016121723A RU 2016121723 A RU2016121723 A RU 2016121723A RU 2016121723 A RU2016121723 A RU 2016121723A
Authority
RU
Russia
Prior art keywords
aekol
nanocapsules
obtaining nanocapsules
carrageenan
shell
Prior art date
Application number
RU2016121723A
Other languages
Russian (ru)
Other versions
RU2644725C2 (en
Inventor
Александр Александрович Кролевец
Original Assignee
Александр Александрович Кролевец
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Александр Александрович Кролевец filed Critical Александр Александрович Кролевец
Priority to RU2016121723A priority Critical patent/RU2644725C2/en
Publication of RU2016121723A publication Critical patent/RU2016121723A/en
Application granted granted Critical
Publication of RU2644725C2 publication Critical patent/RU2644725C2/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82B—NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
    • B82B1/00—Nanostructures formed by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Optics & Photonics (AREA)
  • Manufacturing Of Micro-Capsules (AREA)

Claims (1)

Способ получения нанокапсул АЕКола, характеризующийся тем, что в качестве оболочки нанокапсул используется каррагинана при этом, АЕКол прибавляют в суспензию каррагинана в толуоле в присутствии 0,01 г Е472с в качестве поверхностно-активного вещества, затем перемешивают при 1300 об/мин, после приливают 10 мл хлороформа, после чего полученную суспензию отфильтровывают и сушат при комнатной температуре, при этом соотношение ядро/оболочка составляет 1:1 или 1:3 или 3:1 или 1:5.A method for producing AEKol nanocapsules, characterized in that carrageenan is used as a shell of nanocapsules, while AEKol is added to a suspension of carrageenan in toluene in the presence of 0.01 g of E472c as a surfactant, then stirred at 1300 rpm, after which 10 are added ml of chloroform, after which the resulting suspension is filtered and dried at room temperature, while the ratio of core / shell is 1: 1 or 1: 3 or 3: 1 or 1: 5.
RU2016121723A 2016-06-01 2016-06-01 Method of producing aecol nanocapsules RU2644725C2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU2016121723A RU2644725C2 (en) 2016-06-01 2016-06-01 Method of producing aecol nanocapsules

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2016121723A RU2644725C2 (en) 2016-06-01 2016-06-01 Method of producing aecol nanocapsules

Publications (2)

Publication Number Publication Date
RU2016121723A true RU2016121723A (en) 2017-12-06
RU2644725C2 RU2644725C2 (en) 2018-02-13

Family

ID=60580682

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2016121723A RU2644725C2 (en) 2016-06-01 2016-06-01 Method of producing aecol nanocapsules

Country Status (1)

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RU (1) RU2644725C2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2697252C1 (en) * 2018-09-06 2019-08-13 Александр Александрович Кролевец Method of producing nano-capsules of ethyl nitrate

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2554738C1 (en) * 2014-03-18 2015-06-27 Александр Александрович Кролевец Method of producing chondroitin sulphate nanocapsules in carrageenan
RU2562561C1 (en) * 2014-04-01 2015-09-10 Александр Александрович Кролевец Method of obtaining nanocapsules of vitamins in carrageenan

Also Published As

Publication number Publication date
RU2644725C2 (en) 2018-02-13

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