RU2015140422A - Method for producing metronidazole nanocapsules in carrageenan - Google Patents

Method for producing metronidazole nanocapsules in carrageenan Download PDF

Info

Publication number
RU2015140422A
RU2015140422A RU2015140422A RU2015140422A RU2015140422A RU 2015140422 A RU2015140422 A RU 2015140422A RU 2015140422 A RU2015140422 A RU 2015140422A RU 2015140422 A RU2015140422 A RU 2015140422A RU 2015140422 A RU2015140422 A RU 2015140422A
Authority
RU
Russia
Prior art keywords
nanocapsules
carrageenan
metronidazole
producing
producing metronidazole
Prior art date
Application number
RU2015140422A
Other languages
Russian (ru)
Other versions
RU2646482C2 (en
Inventor
Александр Александрович Кролевец
Original Assignee
Александр Александрович Кролевец
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Александр Александрович Кролевец filed Critical Александр Александрович Кролевец
Priority to RU2015140422A priority Critical patent/RU2646482C2/en
Publication of RU2015140422A publication Critical patent/RU2015140422A/en
Application granted granted Critical
Publication of RU2646482C2 publication Critical patent/RU2646482C2/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82B—NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
    • B82B3/00—Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nanotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Manufacturing & Machinery (AREA)
  • Physics & Mathematics (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Claims (1)

Способ получения нанокапсул метронидазола в каррагинане, характеризующийся тем, что в суспензию алкаррагинана в петролейном эфире и 0,01 г препарата Е472с в качестве поверхностно-активного вещества добавляют порошок метронидазола, затем добавляют 10 мл хлороформа, полученную суспензию нанокапсул отфильтровывают и сушат.A method of producing metronidazole nanocapsules in carrageenan, characterized in that metronidazole powder is added as a surfactant to a suspension of alkarrageenan in petroleum ether and 0.01 g of the preparation E472c, then 10 ml of chloroform is added, the resulting suspension of nanocapsules is filtered off and dried.
RU2015140422A 2015-09-22 2015-09-22 Method for producing nanocapsules of metronidazole in carrageenan RU2646482C2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU2015140422A RU2646482C2 (en) 2015-09-22 2015-09-22 Method for producing nanocapsules of metronidazole in carrageenan

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2015140422A RU2646482C2 (en) 2015-09-22 2015-09-22 Method for producing nanocapsules of metronidazole in carrageenan

Publications (2)

Publication Number Publication Date
RU2015140422A true RU2015140422A (en) 2017-03-28
RU2646482C2 RU2646482C2 (en) 2018-03-05

Family

ID=58505170

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2015140422A RU2646482C2 (en) 2015-09-22 2015-09-22 Method for producing nanocapsules of metronidazole in carrageenan

Country Status (1)

Country Link
RU (1) RU2646482C2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2697252C1 (en) * 2018-09-06 2019-08-13 Александр Александрович Кролевец Method of producing nano-capsules of ethyl nitrate
RU2697253C1 (en) * 2018-09-07 2019-08-13 Александр Александрович Кролевец Method of producing nanocapsules of trinitrotoluene
RU2697842C1 (en) * 2018-09-24 2019-08-21 Александр Александрович Кролевец Method of producing 2,4-dinitroanisole nanocapsules
RU2699014C1 (en) * 2018-10-25 2019-09-03 Александр Александрович Кролевец Method of producing nanocapsules of trinitrotoluene
RU2698192C1 (en) * 2019-03-04 2019-08-23 Александр Александрович Кролевец Method of producing nanocapsules of cyclotrimethylene trinitroamine (hexogen)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004064544A1 (en) * 2003-01-22 2004-08-05 Durafizz, Llc Microencapsulation for sustained delivery of carbon dioxide
KR101392002B1 (en) * 2011-12-01 2014-05-07 강원대학교산학협력단 Amphiphilic polymeric nano capsules crosslinked by nonionic amphiphilic reactive precursor and method thereof
RU2502510C1 (en) * 2012-04-24 2013-12-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования Курская государственная сельскохозяйственная академия имени профессора И.И. Иванова Министерства сельского хозяйства Российской Федерации Method for preparing drug microcapsules of cephalosporin in konjak gum in carbon tetrachloride

Also Published As

Publication number Publication date
RU2646482C2 (en) 2018-03-05

Similar Documents

Publication Publication Date Title
RU2015140422A (en) Method for producing metronidazole nanocapsules in carrageenan
RU2016135130A (en) The method of obtaining nanocapsules of spirulina in sodium alginate
RU2015157420A (en) A method of producing nanocapsules of drugs of the penicillin group in konjac gum
RU2013122331A (en) METHOD FOR OBTAINING ZINC OXIDE MICROCapsules
RU2016117776A (en) The method of obtaining nanocapsules of medicinal plants having a cardiotonic effect
RU2016100640A (en) The method of producing nanocapsules of chloral hydrate in kappa-carrageenan
RU2016100778A (en) The method of obtaining nanocapsules of L-arginine in gellan gum
RU2015140440A (en) A method of producing nanocapsules of drugs of the penicillin group in carrageenan
RU2015147662A (en) The method of obtaining nanocapsules of metal oxides
RU2015131277A (en) A method of obtaining nanocapsules of dry rosehip extract
RU2016114241A (en) The method of obtaining nanocapsules of dry extract of tapinambur
RU2015149454A (en) The method of producing nanocapsules of tetracycline antibiotics in konjac gum
RU2016101691A (en) A method of producing resveratrol nanocapsules in konjac gum
RU2016121723A (en) The method of obtaining nanocapsules AEKol
WO2015149085A8 (en) Water-soluble trans-membrane proteins and methods for the preparation and use thereof
RU2016115924A (en) A method of producing betulin nanocapsules in carrageenan
RU2015118886A (en) A method of producing nanocapsules of rosuvastatin in konjac gum
RU2016114975A (en) The method of obtaining nanocapsules of dry extract of tapinambur
RU2016118196A (en) The method of obtaining nanocapsules of medicinal plants having a cardiotonic effect
RU2014131359A (en) The method of obtaining probiotic nanocapsules
RU2015150712A (en) The method of producing nanocapsules of sodium bicarbonate in carrageenan
RU2015118786A (en) The method of obtaining nanocapsules of medicinal plants with antispasmodic action in konjac gum
RU2016122845A (en) The method of obtaining nanocapsules AEKol
RU2013123067A (en) METHOD FOR BIOINCapsulation
RU2016134390A (en) The method of obtaining nanocapsules AEKol