RU2016100640A - The method of producing nanocapsules of chloral hydrate in kappa-carrageenan - Google Patents

The method of producing nanocapsules of chloral hydrate in kappa-carrageenan Download PDF

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Publication number
RU2016100640A
RU2016100640A RU2016100640A RU2016100640A RU2016100640A RU 2016100640 A RU2016100640 A RU 2016100640A RU 2016100640 A RU2016100640 A RU 2016100640A RU 2016100640 A RU2016100640 A RU 2016100640A RU 2016100640 A RU2016100640 A RU 2016100640A
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RU
Russia
Prior art keywords
carrageenan
kappa
chloral hydrate
nanocapsules
producing nanocapsules
Prior art date
Application number
RU2016100640A
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Russian (ru)
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RU2627581C2 (en
Inventor
Александр Александрович Кролевец
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Александр Александрович Кролевец
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Application filed by Александр Александрович Кролевец filed Critical Александр Александрович Кролевец
Priority to RU2016100640A priority Critical patent/RU2627581C2/en
Publication of RU2016100640A publication Critical patent/RU2016100640A/en
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Publication of RU2627581C2 publication Critical patent/RU2627581C2/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5192Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/11Aldehydes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5161Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nanotechnology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)

Claims (1)

Способ получения нанокапсул хлоральгидрата в каппа-каррагинане, характеризующийся тем, что в суспензию каппа-каррагинана в бутаноле и 0,01 г препарата Е472с в качестве поверхностно-активного вещества добавляют порошок хлоральгидрата, затем добавляют метиленхлоридов, полученную суспензию нанокапсул отфильтровывают и сушат.A method for producing chloral hydrate nanocapsules in kappa-carrageenan, characterized in that chloral hydrate powder is added as a surfactant to a suspension of kappa-carrageenan in butanol and 0.01 g of E472c, then methylene chloride is added, the resulting suspension of nanocapsules is filtered off and dried.
RU2016100640A 2016-01-11 2016-01-11 Method of producing nanocapules of chloralhydrate in kappa-carraginane RU2627581C2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU2016100640A RU2627581C2 (en) 2016-01-11 2016-01-11 Method of producing nanocapules of chloralhydrate in kappa-carraginane

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2016100640A RU2627581C2 (en) 2016-01-11 2016-01-11 Method of producing nanocapules of chloralhydrate in kappa-carraginane

Publications (2)

Publication Number Publication Date
RU2016100640A true RU2016100640A (en) 2017-07-24
RU2627581C2 RU2627581C2 (en) 2017-08-09

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Family Applications (1)

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RU2016100640A RU2627581C2 (en) 2016-01-11 2016-01-11 Method of producing nanocapules of chloralhydrate in kappa-carraginane

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RU (1) RU2627581C2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2691396C1 (en) * 2018-09-03 2019-06-13 Александр Александрович Кролевец Method of producing nanocapsules of dry extract of burdock
RU2686064C1 (en) * 2018-09-24 2019-04-24 Александр Александрович Кролевец Method of producing nanocapsules of dry extract of sweet vetch

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2491939C1 (en) * 2012-05-10 2013-09-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования Курская государственная сельскохозяйственная академия имени профессора И.И. Иванова Министерства сельского хозяйства Российской Федерации Method for preparing drug microcapsules of cephalosporin in konjac gum in chloroform
RU2550918C1 (en) * 2014-05-20 2015-05-20 Александр Александрович Кролевец Method of production of nanocapsules of antibiotics in gellan gum

Also Published As

Publication number Publication date
RU2627581C2 (en) 2017-08-09

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