RU2016135130A - The method of obtaining nanocapsules of spirulina in sodium alginate - Google Patents

The method of obtaining nanocapsules of spirulina in sodium alginate Download PDF

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Publication number
RU2016135130A
RU2016135130A RU2016135130A RU2016135130A RU2016135130A RU 2016135130 A RU2016135130 A RU 2016135130A RU 2016135130 A RU2016135130 A RU 2016135130A RU 2016135130 A RU2016135130 A RU 2016135130A RU 2016135130 A RU2016135130 A RU 2016135130A
Authority
RU
Russia
Prior art keywords
sodium alginate
spirulina
nanocapsules
obtaining nanocapsules
shell
Prior art date
Application number
RU2016135130A
Other languages
Russian (ru)
Other versions
RU2648816C2 (en
RU2016135130A3 (en
Inventor
Александр Александрович Кролевец
Original Assignee
Александр Александрович Кролевец
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Александр Александрович Кролевец filed Critical Александр Александрович Кролевец
Priority to RU2016135130A priority Critical patent/RU2648816C2/en
Publication of RU2016135130A3 publication Critical patent/RU2016135130A3/ru
Publication of RU2016135130A publication Critical patent/RU2016135130A/en
Application granted granted Critical
Publication of RU2648816C2 publication Critical patent/RU2648816C2/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • A61K36/03—Phaeophycota or phaeophyta (brown algae), e.g. Fucus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82B—NANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
    • B82B3/00—Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units

Claims (1)

Способ получения нанокапсул спирулина в альгинате натрия, характеризующийся тем, что в качестве оболочки нанокапсул используют альгинат натрия, при этом порошок спирулина медленно добавляют в суспензию альгината натрия в бутаноле, в присутствии 0,01 г Е472с в качестве поверхностно-активного вещества, затем перемешивают при 1000 об/мин, после приливают 1,2-дихлорэтан, после чего полученную суспензию отфильтровывают и сушат при комнатной температуре, при этом соотношение ядро:оболочка составляет 1:1, или 1:3, или 1:5.A method for producing spirulina nanocapsules in sodium alginate, characterized in that sodium alginate is used as a shell of nanocapsules, while spirulina powder is slowly added to a suspension of sodium alginate in butanol in the presence of 0.01 g of E472c as a surfactant, then mixed with 1000 rpm, after which 1,2-dichloroethane is poured, after which the resulting suspension is filtered off and dried at room temperature, while the ratio of core: shell is 1: 1, or 1: 3, or 1: 5.
RU2016135130A 2016-08-29 2016-08-29 Method of preparation of spirulina nanocapules in sodium alginate RU2648816C2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU2016135130A RU2648816C2 (en) 2016-08-29 2016-08-29 Method of preparation of spirulina nanocapules in sodium alginate

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2016135130A RU2648816C2 (en) 2016-08-29 2016-08-29 Method of preparation of spirulina nanocapules in sodium alginate

Publications (3)

Publication Number Publication Date
RU2016135130A3 RU2016135130A3 (en) 2018-03-05
RU2016135130A true RU2016135130A (en) 2018-03-05
RU2648816C2 RU2648816C2 (en) 2018-03-28

Family

ID=61597110

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2016135130A RU2648816C2 (en) 2016-08-29 2016-08-29 Method of preparation of spirulina nanocapules in sodium alginate

Country Status (1)

Country Link
RU (1) RU2648816C2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2682746C1 (en) * 2018-05-30 2019-03-21 Александр Александрович Кролевец Method for production of bread containing nanostructured spirulina
RU2679683C1 (en) * 2018-08-29 2019-02-12 Александр Александрович Кролевец Method of ice cream production with nanostructured spirulina
RU2707558C1 (en) * 2019-01-09 2019-11-28 Федеральное государственное бюджетное образовательное учреждение высшего образования "Курская государственная сельскохозяйственная академия имени И.И. Иванова" Microencapsulation method of sodium nucleinate
RU2715743C1 (en) * 2019-01-18 2020-03-03 Александр Александрович Кролевец Method of producing probiotic nanocapsules
RU2750269C1 (en) * 2020-11-12 2021-06-25 Федеральное государственное автономное образовательное учреждение высшего образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") Method for producing fig with functional properties

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2134967C1 (en) * 1997-05-30 1999-08-27 Шестаков Константин Алексеевич Method of preparing microcapsulated preparations containing pyrethroid insecticides
WO2004064544A1 (en) * 2003-01-22 2004-08-05 Durafizz, Llc Microencapsulation for sustained delivery of carbon dioxide

Also Published As

Publication number Publication date
RU2648816C2 (en) 2018-03-28
RU2016135130A3 (en) 2018-03-05

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