RU2016121812A - The method of obtaining nanocapsules of medicinal plants having a cardiotonic effect in pectin - Google Patents

The method of obtaining nanocapsules of medicinal plants having a cardiotonic effect in pectin Download PDF

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Publication number
RU2016121812A
RU2016121812A RU2016121812A RU2016121812A RU2016121812A RU 2016121812 A RU2016121812 A RU 2016121812A RU 2016121812 A RU2016121812 A RU 2016121812A RU 2016121812 A RU2016121812 A RU 2016121812A RU 2016121812 A RU2016121812 A RU 2016121812A
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RU
Russia
Prior art keywords
pectin
medicinal plants
cardiotonic effect
obtaining nanocapsules
cardiotonic
Prior art date
Application number
RU2016121812A
Other languages
Russian (ru)
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RU2642056C2 (en
Inventor
Александр Александрович Кролевец
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Александр Александрович Кролевец
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Priority to RU2016121812A priority Critical patent/RU2642056C2/en
Publication of RU2016121812A publication Critical patent/RU2016121812A/en
Application granted granted Critical
Publication of RU2642056C2 publication Critical patent/RU2642056C2/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B02CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
    • B02BPREPARING GRAIN FOR MILLING; REFINING GRANULAR FRUIT TO COMMERCIAL PRODUCTS BY WORKING THE SURFACE
    • B02B3/00Hulling; Husking; Decorticating; Polishing; Removing the awns; Degerming

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Medicinal Preparation (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Claims (1)

Способ получения нанокапсул лекарственных растений, обладающих кардиотоническим действием, характеризующийся тем, что настойку боярышника добавляют в суспензию высоко- или низкоэтерифицированного яблочного или цитрусового пектина в гексане в присутствии 0,01 г препарата Е472с в качестве поверхностно-активного вещества при перемешивании 1300 об/мин, затем полученную суспензию отфильтровывают и сушат при комнатной температуре, при этом соотношение ядро/оболочка составляет 1:3.A method for producing nanocapsules of medicinal plants with a cardiotonic effect, characterized in that the tincture of hawthorn is added to a suspension of high or low esterified apple or citrus pectin in hexane in the presence of 0.01 g of the preparation E472c as a surfactant with stirring at 1300 rpm, then the resulting suspension is filtered off and dried at room temperature, with a core / shell ratio of 1: 3.
RU2016121812A 2016-06-01 2016-06-01 Method of producing nanocapsules of herbs having cardioactive action in pectin RU2642056C2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU2016121812A RU2642056C2 (en) 2016-06-01 2016-06-01 Method of producing nanocapsules of herbs having cardioactive action in pectin

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2016121812A RU2642056C2 (en) 2016-06-01 2016-06-01 Method of producing nanocapsules of herbs having cardioactive action in pectin

Publications (2)

Publication Number Publication Date
RU2016121812A true RU2016121812A (en) 2017-12-06
RU2642056C2 RU2642056C2 (en) 2018-01-23

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Family Applications (1)

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RU2016121812A RU2642056C2 (en) 2016-06-01 2016-06-01 Method of producing nanocapsules of herbs having cardioactive action in pectin

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RU (1) RU2642056C2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2767696C1 (en) * 2020-11-16 2022-03-18 Федеральное государственное автономное образовательное учреждение высшего образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") Method for production of fruit leather with nanostructured extract of hawthorn

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2550923C1 (en) * 2014-03-03 2015-05-20 Александр Александрович Кролевец Method of producing fenbendazole nanocapsules
RU2558079C1 (en) * 2014-04-07 2015-07-27 Александр Александрович Кролевец Method of producing resveratrol nanocapsules in pectin

Also Published As

Publication number Publication date
RU2642056C2 (en) 2018-01-23

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