RU2016100645A - The method of obtaining microcapsules of sedatives in gelatin - Google Patents

The method of obtaining microcapsules of sedatives in gelatin Download PDF

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Publication number
RU2016100645A
RU2016100645A RU2016100645A RU2016100645A RU2016100645A RU 2016100645 A RU2016100645 A RU 2016100645A RU 2016100645 A RU2016100645 A RU 2016100645A RU 2016100645 A RU2016100645 A RU 2016100645A RU 2016100645 A RU2016100645 A RU 2016100645A
Authority
RU
Russia
Prior art keywords
gelatin
sedatives
obtaining microcapsules
microcapsules
added
Prior art date
Application number
RU2016100645A
Other languages
Russian (ru)
Other versions
RU2632304C2 (en
Inventor
Александр Александрович Кролевец
Original Assignee
Александр Александрович Кролевец
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Александр Александрович Кролевец filed Critical Александр Александрович Кролевец
Priority to RU2016100645A priority Critical patent/RU2632304C2/en
Publication of RU2016100645A publication Critical patent/RU2016100645A/en
Application granted granted Critical
Publication of RU2632304C2 publication Critical patent/RU2632304C2/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/533—Leonurus (motherwort)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/84—Valerianaceae (Valerian family), e.g. valerian
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
    • A61K9/5057—Gelatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Manufacturing Of Micro-Capsules (AREA)

Claims (1)

Способ получения микрокапсул седативных средств в желатине, характеризующийся тем, что в качестве оболочки микрокапсул используется желатин при этом, настойку седативного средства прибавляют в суспензию желатина в петролейном эфире, в присутствии 0,01 г Е472с в качестве поверхностно-активного вещества, затем перемешивают при 1300 об/мин, после приливают 5 мл гептана, после чего полученную суспензию отфильтровывают и сушат при комнатной температуре.A method of producing microcapsules of sedatives in gelatin, characterized in that gelatin is used as a shell of microcapsules, while tincture of a sedative is added to a suspension of gelatin in petroleum ether, in the presence of 0.01 g of E472c as a surfactant, then stirred at 1300 rpm, after which 5 ml of heptane are added, after which the resulting suspension is filtered off and dried at room temperature.
RU2016100645A 2016-01-11 2016-01-11 Method for production of sedative means microcapsules in gelatine RU2632304C2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU2016100645A RU2632304C2 (en) 2016-01-11 2016-01-11 Method for production of sedative means microcapsules in gelatine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2016100645A RU2632304C2 (en) 2016-01-11 2016-01-11 Method for production of sedative means microcapsules in gelatine

Publications (2)

Publication Number Publication Date
RU2016100645A true RU2016100645A (en) 2017-07-13
RU2632304C2 RU2632304C2 (en) 2017-10-03

Family

ID=59497066

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2016100645A RU2632304C2 (en) 2016-01-11 2016-01-11 Method for production of sedative means microcapsules in gelatine

Country Status (1)

Country Link
RU (1) RU2632304C2 (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU598629A1 (en) * 1976-08-16 1978-03-25 Московский Ордена Ленина И Ордена Трудового Красного Знамени Государственный Университет Им. М.В.Ломоносова Method of obtaining micro-capsules
RU2496483C1 (en) * 2012-03-20 2013-10-27 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Юго-Западный государственный университет" (ЮЗ ГУ) Method for preparing microcapsules

Also Published As

Publication number Publication date
RU2632304C2 (en) 2017-10-03

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