RU2015137757A3 - - Google Patents
Download PDFInfo
- Publication number
- RU2015137757A3 RU2015137757A3 RU2015137757A RU2015137757A RU2015137757A3 RU 2015137757 A3 RU2015137757 A3 RU 2015137757A3 RU 2015137757 A RU2015137757 A RU 2015137757A RU 2015137757 A RU2015137757 A RU 2015137757A RU 2015137757 A3 RU2015137757 A3 RU 2015137757A3
- Authority
- RU
- Russia
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13154390.2 | 2013-02-07 | ||
| EP13154390 | 2013-02-07 | ||
| PCT/EP2014/000316 WO2014121931A1 (en) | 2013-02-07 | 2014-02-06 | Pyridazinone-amides derivatives |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| RU2015137757A RU2015137757A (ru) | 2017-03-13 |
| RU2015137757A3 true RU2015137757A3 (enExample) | 2018-01-17 |
| RU2666899C2 RU2666899C2 (ru) | 2018-09-13 |
Family
ID=47681772
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2015137757A RU2666899C2 (ru) | 2013-02-07 | 2014-02-06 | Производные пиридазинон-амидов |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US9567320B2 (enExample) |
| EP (1) | EP2953944B1 (enExample) |
| JP (1) | JP6483624B2 (enExample) |
| KR (1) | KR102293952B1 (enExample) |
| CN (1) | CN104968658B (enExample) |
| AU (1) | AU2014214321B2 (enExample) |
| BR (1) | BR112015018663A2 (enExample) |
| CA (1) | CA2900431C (enExample) |
| DK (1) | DK2953944T3 (enExample) |
| ES (1) | ES2634627T3 (enExample) |
| HR (1) | HRP20171076T1 (enExample) |
| HU (1) | HUE032863T2 (enExample) |
| IL (1) | IL240290B (enExample) |
| LT (1) | LT2953944T (enExample) |
| MX (1) | MX364486B (enExample) |
| PL (1) | PL2953944T3 (enExample) |
| PT (1) | PT2953944T (enExample) |
| RS (1) | RS56331B1 (enExample) |
| RU (1) | RU2666899C2 (enExample) |
| SG (1) | SG11201506100XA (enExample) |
| SI (1) | SI2953944T1 (enExample) |
| WO (1) | WO2014121931A1 (enExample) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102551597B1 (ko) * | 2015-02-06 | 2023-07-05 | 메르크 파텐트 게엠베하 | Irak 억제제로서 피리다지논 매크로사이클 및 이의 용도 |
| DK3286181T3 (da) | 2015-04-22 | 2021-04-06 | Rigel Pharmaceuticals Inc | Pyrazolforbindelser og fremgangsmåde til fremstilling og anvendelse af forbindelserne |
| KR102670695B1 (ko) * | 2015-09-18 | 2024-06-05 | 메르크 파텐트 게엠베하 | Irak 억제제로서의 헤테로아릴 화합물 및 이의 용도 |
| EP3365335B1 (en) | 2015-10-23 | 2024-02-14 | Array Biopharma, Inc. | 2-aryl- and 2-heteroaryl-substituted 2-pyridazin-3(2h)-one compounds as inhibitors of fgfr tyrosine kinases |
| TW202340194A (zh) | 2017-02-16 | 2023-10-16 | 美商基利科學股份有限公司 | 吡咯并[1,2-b]嗒𠯤衍生物 |
| MX2020003190A (es) | 2017-09-22 | 2020-11-11 | Kymera Therapeutics Inc | Degradadores de proteinas y usos de los mismos. |
| WO2019060693A1 (en) | 2017-09-22 | 2019-03-28 | Kymera Therapeutics, Inc. | CRBN LIGANDS AND USES THEREOF |
| WO2019111218A1 (en) | 2017-12-08 | 2019-06-13 | Cadila Healthcare Limited | Novel heterocyclic compounds as irak4 inhibitors |
| IL315310A (en) | 2017-12-26 | 2024-10-01 | Kymera Therapeutics Inc | Irak degraders and uses thereof |
| EP3737666A4 (en) | 2018-01-12 | 2022-01-05 | Kymera Therapeutics, Inc. | PROTEIN DEGRADATION AGENTS AND ASSOCIATED USES |
| US11512080B2 (en) | 2018-01-12 | 2022-11-29 | Kymera Therapeutics, Inc. | CRBN ligands and uses thereof |
| ES3041367T3 (en) * | 2018-06-04 | 2025-11-11 | Ohio State Innovation Foundation | Eaat2 activators and methods of using thereof |
| US11292792B2 (en) | 2018-07-06 | 2022-04-05 | Kymera Therapeutics, Inc. | Tricyclic CRBN ligands and uses thereof |
| US12454520B2 (en) | 2018-07-06 | 2025-10-28 | Kymera Therapeutics, Inc. | Protein degraders and uses thereof |
| TWI721483B (zh) | 2018-07-13 | 2021-03-11 | 美商基利科學股份有限公司 | 吡咯并[1,2-b]嗒𠯤衍生物 |
| WO2020097258A1 (en) * | 2018-11-06 | 2020-05-14 | Edgewise Therapeutics, Inc. | Pyridazinone compounds and uses thereof |
| KR102885525B1 (ko) | 2018-11-06 | 2025-11-13 | 엣지와이즈 테라퓨틱스, 인크. | 피리다지논 화합물 및 이의 용도 |
| SMT202300355T1 (it) | 2018-11-06 | 2024-01-10 | Edgewise Therapeutics Inc | Composti di piridazinone e loro usi |
| AU2019389174A1 (en) | 2018-11-30 | 2021-07-01 | Kymera Therapeutics, Inc. | Irak degraders and uses thereof |
| WO2020131627A1 (en) | 2018-12-19 | 2020-06-25 | Array Biopharma Inc. | Substituted pyrazolo[1,5-a]pyridine compounds as inhibitors of fgfr tyrosine kinases |
| US12351571B2 (en) | 2018-12-19 | 2025-07-08 | Array Biopharma Inc. | Substituted quinoxaline compounds as inhibitors of FGFR tyrosine kinases |
| PH12022500002A1 (en) | 2019-06-28 | 2023-04-03 | Kymera Therapeutics Inc | Irak degraders and uses thereof |
| US12558427B2 (en) | 2019-07-17 | 2026-02-24 | Kymera Therapeutics, Inc. | IRAK degraders and uses thereof |
| JP2022545542A (ja) | 2019-08-30 | 2022-10-27 | ライジェル ファーマシューティカルズ， インコーポレイテッド | ピラゾール化合物、その製剤並びに化合物及び／又は製剤を使用する方法 |
| WO2021119159A1 (en) | 2019-12-10 | 2021-06-17 | Kymera Therapeutics, Inc. | Irak degraders and uses thereof |
| CA3161878A1 (en) | 2019-12-17 | 2021-06-24 | Matthew M. Weiss | Irak degraders and uses thereof |
| EP4076524A4 (en) | 2019-12-17 | 2023-11-29 | Kymera Therapeutics, Inc. | IRAQ DEGRADERS AND USES THEREOF |
| EP4149467A1 (en) * | 2020-05-13 | 2023-03-22 | Edgewise Therapeutics, Inc. | Substituted pyridazinone for use in the treatment of neuromuscular diseases |
| WO2021231630A1 (en) * | 2020-05-13 | 2021-11-18 | Edgewise Therapeutics, Inc. | Substituted pyridazinone for use in the treatment of neuromuscular diseases |
| EP4473968A3 (en) | 2020-05-13 | 2025-03-26 | Edgewise Therapeutics, Inc. | Pyridazinone compounds and uses thereof |
| EP4161521A4 (en) | 2020-06-03 | 2024-07-10 | Kymera Therapeutics, Inc. | DEUTERED IRAQ DEGRADERS AND USES THEREOF |
| TW202210483A (zh) | 2020-06-03 | 2022-03-16 | 美商凱麥拉醫療公司 | Irak降解劑之結晶型 |
| AR124547A1 (es) | 2020-12-30 | 2023-04-05 | Kymera Therapeutics Inc | Degradadores de irak y sus usos |
| WO2022174268A1 (en) | 2021-02-15 | 2022-08-18 | Kymera Therapeutics, Inc. | Irak4 degraders and uses thereof |
| CN114957132A (zh) * | 2021-02-20 | 2022-08-30 | 中国科学院上海药物研究所 | 含s构型的氨基苯甲酰胺基哒嗪酮类化合物、其制备方法、药物组合物及应用 |
| WO2022187303A1 (en) | 2021-03-03 | 2022-09-09 | Rigel Pharmaceuticals, Inc. | A method for treating a disease or condition using a pyrazole compound or formulation thereof |
| US20240216362A1 (en) * | 2021-04-19 | 2024-07-04 | Shanghai Yao Yuan Biotechnology Co., Ltd. | Benzothiazole and quinoline derivatives for use in treating kawasaki disease |
| CA3217792A1 (en) | 2021-05-07 | 2022-11-10 | Kymera Therapeutics, Inc | Cdk2 degraders and uses thereof |
| JP2024540080A (ja) | 2021-10-29 | 2024-10-31 | カイメラ セラピューティクス， インコーポレイテッド | Ｉｒａｋ４分解剤およびその合成 |
| EP4472967A4 (en) | 2022-01-31 | 2026-04-15 | Kymera Therapeutics Inc | Iraqi Degradation Agents and Their Uses |
| ES3075943T3 (en) | 2022-03-23 | 2026-08-10 | Rigel Pharmaceuticals Inc | Pyrimid-2-yl-pyrazole compounds as irak inhibitors |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3734083A1 (de) * | 1987-10-08 | 1989-04-20 | Heumann Pharma Gmbh & Co | Benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| AU5310096A (en) * | 1995-03-17 | 1996-10-08 | Du Pont Merck Pharmaceutical Company, The | Cyclic urea hiv protease inhibitors |
| JP2000247959A (ja) * | 1999-02-26 | 2000-09-12 | Kowa Co | ピリダジン−３−オン誘導体及びこれを含有する医薬 |
| EP1434579B1 (en) * | 2001-10-09 | 2011-06-08 | Amgen Inc. | Imidazole derivatives as antiinflammatory agents |
| BRPI0408359A (pt) * | 2003-03-18 | 2006-03-21 | Kowa Co | derivados de fenilpiridazina solúveis em água e medicamentos contendo os mesmos |
| DE102006037478A1 (de) * | 2006-08-10 | 2008-02-14 | Merck Patent Gmbh | 2-(Heterocyclylbenzyl)-pyridazinonderivate |
| JP2008063265A (ja) * | 2006-09-06 | 2008-03-21 | Kyorin Pharmaceut Co Ltd | ピリダジノン誘導体及びそれらを有効成分とするｐｄｅ阻害剤 |
| NZ575410A (en) * | 2006-09-07 | 2012-03-30 | Biogen Idec Inc | 2-(1H-Indazol-3-ylamino)-1H-benzimidazole derivatives |
| DE102007025717A1 (de) * | 2007-06-01 | 2008-12-11 | Merck Patent Gmbh | Arylether-pyridazinonderivate |
| DE102007032507A1 (de) * | 2007-07-12 | 2009-04-02 | Merck Patent Gmbh | Pyridazinonderivate |
| DE102008062826A1 (de) * | 2008-12-23 | 2010-07-01 | Merck Patent Gmbh | Pyridazinonderivate |
| HUE029617T2 (en) * | 2010-12-20 | 2017-03-28 | Merck Serono Sa | Indazolyl triazole derivatives as IRAK inhibitors |
| EP2688872A4 (en) * | 2011-03-22 | 2014-08-27 | Merck Sharp & Dohme | AMIDOPYRAZOLHEMMER OF INTERLEUKIN RECEPTOR-MEDIATED KINASES |
| ES2639717T3 (es) * | 2013-02-07 | 2017-10-30 | Merck Patent Gmbh | Derivados de piridazinona macrocíclicos |
-
2014
- 2014-02-06 JP JP2015556421A patent/JP6483624B2/ja not_active Expired - Fee Related
- 2014-02-06 HR HRP20171076TT patent/HRP20171076T1/hr unknown
- 2014-02-06 KR KR1020157024342A patent/KR102293952B1/ko not_active Expired - Fee Related
- 2014-02-06 AU AU2014214321A patent/AU2014214321B2/en not_active Ceased
- 2014-02-06 SI SI201430307T patent/SI2953944T1/sl unknown
- 2014-02-06 RU RU2015137757A patent/RU2666899C2/ru active
- 2014-02-06 DK DK14703537.2T patent/DK2953944T3/en active
- 2014-02-06 BR BR112015018663A patent/BR112015018663A2/pt not_active Application Discontinuation
- 2014-02-06 RS RS20170743A patent/RS56331B1/sr unknown
- 2014-02-06 SG SG11201506100XA patent/SG11201506100XA/en unknown
- 2014-02-06 US US14/766,671 patent/US9567320B2/en not_active Expired - Fee Related
- 2014-02-06 PL PL14703537T patent/PL2953944T3/pl unknown
- 2014-02-06 CN CN201480007676.1A patent/CN104968658B/zh not_active Expired - Fee Related
- 2014-02-06 EP EP14703537.2A patent/EP2953944B1/en active Active
- 2014-02-06 WO PCT/EP2014/000316 patent/WO2014121931A1/en not_active Ceased
- 2014-02-06 LT LTEP14703537.2T patent/LT2953944T/lt unknown
- 2014-02-06 ES ES14703537.2T patent/ES2634627T3/es active Active
- 2014-02-06 PT PT147035372T patent/PT2953944T/pt unknown
- 2014-02-06 MX MX2015010125A patent/MX364486B/es active IP Right Grant
- 2014-02-06 CA CA2900431A patent/CA2900431C/en not_active Expired - Fee Related
- 2014-02-06 HU HUE14703537A patent/HUE032863T2/en unknown
-
2015
- 2015-08-02 IL IL240290A patent/IL240290B/en active IP Right Grant
-
2016
- 2016-11-23 US US15/360,288 patent/US20170071936A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR112021000792B8 (enExample) | ||
| AT524874A5 (enExample) | ||
| AT524834A2 (enExample) | ||
| AT521543A3 (enExample) | ||
| BR102019026286B1 (pt) | Método e aparelho para o avanço de produtos a serem moldados | |
| BR102019025884B1 (pt) | Sistema de segurança aprimorado para máquinas de operação de autopropulsão | |
| BR102019023514B1 (pt) | Método para determinar a massa de ar preso em cada cilindro de um motor a combustão interna | |
| BR112020016338B1 (pt) | Dispositivo para tratamento de tecido corporal | |
| BR112021001374B1 (pt) | Composição farmacêutica para o tratamento da hipertensão e seu uso | |
| BR112021001128B1 (pt) | Composição de cimento para impressão 3d, método de impressão 3d, kit para a preparação de uma composição de cimento para impressão 3d e método de impressão 3d implementando o kit | |
| BR112021001186B1 (pt) | Aparelho para o tratamento de celulite para tratar expressões de celulite na pele de um paciente associadas a um local de tratamento de septos | |
| BR112021000922B1 (pt) | Tela de filtro, e, método para purificar água de alimentação | |
| BR112020026077B1 (pt) | Recipiente com estrutura encaixável | |
| BR112020026721B1 (pt) | Aparelho de moldagem para modar uma folha de um material contendo alcaloides | |
| BR102019012845B1 (pt) | Montagens de guia de entrada de piso de compartimento de carga retráteis para carregamentos paletizados em aeronaves de carga e aeronave e carga | |
| BR112020023832B1 (pt) | Amostra de calibração de sistemas de análise multiespectral e método para calibração de sistemas de análise multiespectral | |
| BR112020024987B1 (pt) | Método, montagem e sistema para prover uma estrutura de base, método industrial, e, braço mecânico | |
| BR112020023823B1 (pt) | Distribuidor | |
| BR112020022482B1 (pt) | Composição, anticorpo anti-cd24, anticorpo biespecífico e receptor de antígeno quimérico | |
| BR112020022658B1 (pt) | Método para estimar um nível de pressão sonora, sistema de fone de ouvido, fone de ouvido e uso do fone de ouvido | |
| BR112020022516B1 (pt) | Processo para degomagem enzimática de óleo | |
| BR112020021042B1 (pt) | Compostos de carboxamidas bicíclicas, composição farmacêutica e uso das mesmas | |
| BR112020020812B1 (pt) | Composições de tratamento de superfícies duras, seu uso, método para proporcionar ação antimicrobiana residual e substrato relacionado | |
| BR102019000241B1 (pt) | Veículo modular, configurável, sobre plataforma de chassis comum, e métodos e sistemas associados | |
| BR102018073077B1 (pt) | Processo de extração de gelatina de resíduos de couro curtido ao cromo wet blue |