HRP20171076T1 - Derivati piridazinon-amida - Google Patents

Derivati piridazinon-amida Download PDF

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Publication number
HRP20171076T1
HRP20171076T1 HRP20171076TT HRP20171076T HRP20171076T1 HR P20171076 T1 HRP20171076 T1 HR P20171076T1 HR P20171076T T HRP20171076T T HR P20171076TT HR P20171076 T HRP20171076 T HR P20171076T HR P20171076 T1 HRP20171076 T1 HR P20171076T1
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Croatia
Prior art keywords
disease
compound
formula
syndrome
alkyl
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HRP20171076TT
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English (en)
Croatian (hr)
Inventor
Catherine Jorand-Lebrun
Santosh Kulkarni
Stefano Crosignani
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Merck Patent Gmbh
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Publication of HRP20171076T1 publication Critical patent/HRP20171076T1/hr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Reproductive Health (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
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HRP20171076TT 2013-02-07 2014-02-06 Derivati piridazinon-amida HRP20171076T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13154390 2013-02-07
PCT/EP2014/000316 WO2014121931A1 (en) 2013-02-07 2014-02-06 Pyridazinone-amides derivatives
EP14703537.2A EP2953944B1 (en) 2013-02-07 2014-02-06 Pyridazinone-amides derivatives

Publications (1)

Publication Number Publication Date
HRP20171076T1 true HRP20171076T1 (hr) 2017-10-06

Family

ID=47681772

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20171076TT HRP20171076T1 (hr) 2013-02-07 2014-02-06 Derivati piridazinon-amida

Country Status (22)

Country Link
US (2) US9567320B2 (enExample)
EP (1) EP2953944B1 (enExample)
JP (1) JP6483624B2 (enExample)
KR (1) KR102293952B1 (enExample)
CN (1) CN104968658B (enExample)
AU (1) AU2014214321B2 (enExample)
BR (1) BR112015018663A2 (enExample)
CA (1) CA2900431C (enExample)
DK (1) DK2953944T3 (enExample)
ES (1) ES2634627T3 (enExample)
HR (1) HRP20171076T1 (enExample)
HU (1) HUE032863T2 (enExample)
IL (1) IL240290B (enExample)
LT (1) LT2953944T (enExample)
MX (1) MX364486B (enExample)
PL (1) PL2953944T3 (enExample)
PT (1) PT2953944T (enExample)
RS (1) RS56331B1 (enExample)
RU (1) RU2666899C2 (enExample)
SG (1) SG11201506100XA (enExample)
SI (1) SI2953944T1 (enExample)
WO (1) WO2014121931A1 (enExample)

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SG11201707752SA (en) 2015-04-22 2017-11-29 Rigel Pharmaceuticals Inc Pyrazole compounds and method for making and using the compounds
WO2017049068A1 (en) * 2015-09-18 2017-03-23 Merck Patent Gmbh Heteroaryl compounds as irak inhibitors and uses thereof
EP3365335B1 (en) 2015-10-23 2024-02-14 Array Biopharma, Inc. 2-aryl- and 2-heteroaryl-substituted 2-pyridazin-3(2h)-one compounds as inhibitors of fgfr tyrosine kinases
JOP20180011A1 (ar) 2017-02-16 2019-01-30 Gilead Sciences Inc مشتقات بيرولو [1، 2-b]بيريدازين
WO2019060742A1 (en) 2017-09-22 2019-03-28 Kymera Therapeutics, Inc AGENTS FOR DEGRADING PROTEINS AND USES THEREOF
US11358948B2 (en) 2017-09-22 2022-06-14 Kymera Therapeutics, Inc. CRBN ligands and uses thereof
WO2019111218A1 (en) 2017-12-08 2019-06-13 Cadila Healthcare Limited Novel heterocyclic compounds as irak4 inhibitors
IL315310A (en) 2017-12-26 2024-10-01 Kymera Therapeutics Inc Irak degraders and uses thereof
WO2019140387A1 (en) 2018-01-12 2019-07-18 Kymera Therapeutics, Inc. Crbn ligands and uses thereof
US11485743B2 (en) 2018-01-12 2022-11-01 Kymera Therapeutics, Inc. Protein degraders and uses thereof
JP2021527636A (ja) * 2018-06-04 2021-10-14 オハイオ・ステイト・イノベーション・ファウンデーション Ｅａａｔ２活性化因子およびその使用方法
WO2020010177A1 (en) 2018-07-06 2020-01-09 Kymera Therapeutics, Inc. Tricyclic crbn ligands and uses thereof
WO2020010227A1 (en) 2018-07-06 2020-01-09 Kymera Therapeutics, Inc. Protein degraders and uses thereof
TWI721483B (zh) 2018-07-13 2021-03-11 美商基利科學股份有限公司 吡咯并[1,2-b]嗒𠯤衍生物
CN113272280B (zh) * 2018-11-06 2026-01-09 艾知怀斯治疗学公司 哒嗪酮化合物及其用途
CA3118908A1 (en) 2018-11-06 2020-05-14 Edgewise Therapeutics, Inc. Pyridazinone compounds and uses thereof
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