RU2015128446A - The method of obtaining nanocapsules of medicinal plants with sedative effect - Google Patents

The method of obtaining nanocapsules of medicinal plants with sedative effect Download PDF

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Publication number
RU2015128446A
RU2015128446A RU2015128446A RU2015128446A RU2015128446A RU 2015128446 A RU2015128446 A RU 2015128446A RU 2015128446 A RU2015128446 A RU 2015128446A RU 2015128446 A RU2015128446 A RU 2015128446A RU 2015128446 A RU2015128446 A RU 2015128446A
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RU
Russia
Prior art keywords
nanocapsules
medicinal plants
sedative effect
tincture
obtaining nanocapsules
Prior art date
Application number
RU2015128446A
Other languages
Russian (ru)
Other versions
RU2613761C2 (en
Inventor
Александр Александрович Кролевец
Original Assignee
Александр Александрович Кролевец
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Application filed by Александр Александрович Кролевец filed Critical Александр Александрович Кролевец
Priority to RU2015128446A priority Critical patent/RU2613761C2/en
Publication of RU2015128446A publication Critical patent/RU2015128446A/en
Application granted granted Critical
Publication of RU2613761C2 publication Critical patent/RU2613761C2/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/84Valerianaceae (Valerian family), e.g. valerian
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/533Leonurus (motherwort)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82BNANOSTRUCTURES FORMED BY MANIPULATION OF INDIVIDUAL ATOMS, MOLECULES, OR LIMITED COLLECTIONS OF ATOMS OR MOLECULES AS DISCRETE UNITS; MANUFACTURE OR TREATMENT THEREOF
    • B82B3/00Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units

Claims (1)

Способ получения нанокапсул лекарственных растений, обладающих седативным действием, характеризующийся тем, что настойки валерьяны, пустырника или пиона уклоняющегося добавляют в суспензию натрий карбоксиметилцеллюлозы в ацетоне в присутствии 0,01 г препарата Е472с в качестве поверхностно-активного вещества при перемешивании при 1300 об./мин, полученную суспензию отфильтровывают и сушат при комнатной температуре, причем соотношение ядро: оболочка в случае получения нанокапсул настойки пустырника составляет 1:3, 1:1, 5:1 или 1:5, в случае получения нанокапсул настойки валерьяны 1:3, 1:1, 5:1, 1:5, в случае получения нанокапсул настойки пиона уклоняющегося 1:3, 1:5.A method of producing nanocapsules of medicinal plants with a sedative effect, characterized in that the tinctures of valerian, motherwort or evading peony are added to a suspension of sodium carboxymethyl cellulose in acetone in the presence of 0.01 g of the preparation E472c as a surfactant with stirring at 1300 rpm. , the resulting suspension is filtered and dried at room temperature, the core: shell ratio in the case of obtaining nanocapsules of motherwort tincture is 1: 3, 1: 1, 5: 1 or 1: 5, in the case of Ia nanocapsules valerian tincture 1: 3, 1: 1, 5: 1, 1: 5, in the case of obtaining nanocapsules peony deviating tincture 1: 3, 1: 5.
RU2015128446A 2015-07-13 2015-07-13 Method for praparing nanocapsules of medicinal plants having sedative effect RU2613761C2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU2015128446A RU2613761C2 (en) 2015-07-13 2015-07-13 Method for praparing nanocapsules of medicinal plants having sedative effect

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU2015128446A RU2613761C2 (en) 2015-07-13 2015-07-13 Method for praparing nanocapsules of medicinal plants having sedative effect

Publications (2)

Publication Number Publication Date
RU2015128446A true RU2015128446A (en) 2017-01-19
RU2613761C2 RU2613761C2 (en) 2017-03-21

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU2015128446A RU2613761C2 (en) 2015-07-13 2015-07-13 Method for praparing nanocapsules of medicinal plants having sedative effect

Country Status (1)

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Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2134967C1 (en) * 1997-05-30 1999-08-27 Шестаков Константин Алексеевич Method of preparing microcapsulated preparations containing pyrethroid insecticides
RU2378830C2 (en) * 2003-08-22 2010-01-20 Даниско А/С Encapsulated antimicrobial material

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Publication number Publication date
RU2613761C2 (en) 2017-03-21

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