RU2014128298A - Комбинация факторов роста, цитокинов, антибактериальных/антивирусных факторов, факторов стволовых клеток, белков комплемента с3а/с4а и хемотаксических факторов - Google Patents

Комбинация факторов роста, цитокинов, антибактериальных/антивирусных факторов, факторов стволовых клеток, белков комплемента с3а/с4а и хемотаксических факторов Download PDF

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RU2014128298A
RU2014128298A RU2014128298A RU2014128298A RU2014128298A RU 2014128298 A RU2014128298 A RU 2014128298A RU 2014128298 A RU2014128298 A RU 2014128298A RU 2014128298 A RU2014128298 A RU 2014128298A RU 2014128298 A RU2014128298 A RU 2014128298A
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factors
combination
stem cell
combination according
cytokines
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RU2014128298A
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RU2645082C2 (ru
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Альберто Барторелли
Мария Роза Гобби
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Бионест Лтд.
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Priority claimed from IT002442A external-priority patent/ITMI20112442A1/it
Priority claimed from IT002444A external-priority patent/ITMI20112444A1/it
Priority claimed from IT002437A external-priority patent/ITMI20112437A1/it
Application filed by Бионест Лтд. filed Critical Бионест Лтд.
Publication of RU2014128298A publication Critical patent/RU2014128298A/ru
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Abstract

1. Комбинация цитокинов, факторов роста, хемотаксических факторов, факторов стволовых клеток и антибактериальных/антивирусных факторов следующего состава:Цитокины (пкг/мг)Факторы роста (пкг/мг)Факторы стволовых клеток (пкг/мг)Хемотаксические факторы (пкг/мг)Антибактериальные/антивирусные факторы (мкг/мг)Белки комплемента2. Комбинация по п.1, получаемая путем экстрагирования молозива.3. Комбинация по п. 1, получаемая путем экстрагирования плаценты.4. Комбинация по п. 1, получаемая путем экстрагирования сыворотки, собранной за 5-15 дней до родов.5. Комбинация по пп. 1-4 для применения в лечении заболеваний, требующих восстановления тканей и регенерации и для замещения терапии стволовыми клетками.6. Комбинация по п. 5, где заболевания могут быть патологиями костной системы травматического либо дегенеративного происхождения, метастатические повреждения костей, атрофия нижне- или верхнечелюстного альвеолярного отростка, переломы костей, кариесные полости и воспаление пульпы.7. Комбинация по пп. 1-4 для применения в качестве заполнителей в дерматологии, пластической и эстетической хирургии, возможно, в комбинации с биоматериалом.8. Комбинация по п. 7, где биоматериал выбирают из коллагена, гиалуроновой кислоты, матригеля, гидроколлоидов, полилактидов, полигликолидов, поликапролактонов и т.п.9. Фармацевтические композиции, содержащие комбинации по пп. 1-4 в качестве активных ингредиентов в смеси с приемлемыми носителями и/или эксципиентами.10. Фармацевтические композиции по п. 9 для парентерального введения.11. Фармацевтические композиции по п. 9 для местного введения.12. Имплантируемые материалы, содержащие комбинацию по п. 1 в форме каркасов, цементирующих приспособл

Claims (12)

1. Комбинация цитокинов, факторов роста, хемотаксических факторов, факторов стволовых клеток и антибактериальных/антивирусных факторов следующего состава:
Цитокины (пкг/мг)
Figure 00000001
Факторы роста (пкг/мг)
Figure 00000002
Figure 00000003
Факторы стволовых клеток (пкг/мг)
Figure 00000004
Хемотаксические факторы (пкг/мг)
Figure 00000005
Антибактериальные/антивирусные факторы (мкг/мг)
Figure 00000006
Белки комплемента
Figure 00000007
2. Комбинация по п.1, получаемая путем экстрагирования молозива.
3. Комбинация по п. 1, получаемая путем экстрагирования плаценты.
4. Комбинация по п. 1, получаемая путем экстрагирования сыворотки, собранной за 5-15 дней до родов.
5. Комбинация по пп. 1-4 для применения в лечении заболеваний, требующих восстановления тканей и регенерации и для замещения терапии стволовыми клетками.
6. Комбинация по п. 5, где заболевания могут быть патологиями костной системы травматического либо дегенеративного происхождения, метастатические повреждения костей, атрофия нижне- или верхнечелюстного альвеолярного отростка, переломы костей, кариесные полости и воспаление пульпы.
7. Комбинация по пп. 1-4 для применения в качестве заполнителей в дерматологии, пластической и эстетической хирургии, возможно, в комбинации с биоматериалом.
8. Комбинация по п. 7, где биоматериал выбирают из коллагена, гиалуроновой кислоты, матригеля, гидроколлоидов, полилактидов, полигликолидов, поликапролактонов и т.п.
9. Фармацевтические композиции, содержащие комбинации по пп. 1-4 в качестве активных ингредиентов в смеси с приемлемыми носителями и/или эксципиентами.
10. Фармацевтические композиции по п. 9 для парентерального введения.
11. Фармацевтические композиции по п. 9 для местного введения.
12. Имплантируемые материалы, содержащие комбинацию по п. 1 в форме каркасов, цементирующих приспособлений, суппортов, реабсорбируемых или нереабсорбируемых имплантатов.
RU2014128298A 2011-12-30 2012-12-27 Комбинация факторов роста, цитокинов, антибактериальных/антивирусных факторов, факторов стволовых клеток, белков комплемента с3а/с4а и хемотаксических факторов RU2645082C2 (ru)

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