RU2014122189A - Способы снижения частоты и тяжести острых приступов астмы - Google Patents

Способы снижения частоты и тяжести острых приступов астмы Download PDF

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Publication number
RU2014122189A
RU2014122189A RU2014122189/15A RU2014122189A RU2014122189A RU 2014122189 A RU2014122189 A RU 2014122189A RU 2014122189/15 A RU2014122189/15 A RU 2014122189/15A RU 2014122189 A RU2014122189 A RU 2014122189A RU 2014122189 A RU2014122189 A RU 2014122189A
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RU
Russia
Prior art keywords
antibody
binding fragment
patient
seizures
antigen binding
Prior art date
Application number
RU2014122189/15A
Other languages
English (en)
Russian (ru)
Inventor
Нестор МОЛФИНО
Джозеф ПАРКЕР
Original Assignee
МЕДИММЬЮН, ЭлЭлСи
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by МЕДИММЬЮН, ЭлЭлСи filed Critical МЕДИММЬЮН, ЭлЭлСи
Publication of RU2014122189A publication Critical patent/RU2014122189A/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
RU2014122189/15A 2011-11-01 2012-10-28 Способы снижения частоты и тяжести острых приступов астмы RU2014122189A (ru)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201161554110P 2011-11-01 2011-11-01
US61/554,110 2011-11-01
US201161562544P 2011-11-22 2011-11-22
US61/562,544 2011-11-22
US201261645699P 2012-05-11 2012-05-11
US61/645,699 2012-05-11
PCT/US2012/062349 WO2013066780A2 (en) 2011-11-01 2012-10-28 Methods for reducing the frequency and severity of acute exacerbations of asthma

Publications (1)

Publication Number Publication Date
RU2014122189A true RU2014122189A (ru) 2015-12-10

Family

ID=48193002

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2014122189/15A RU2014122189A (ru) 2011-11-01 2012-10-28 Способы снижения частоты и тяжести острых приступов астмы

Country Status (11)

Country Link
US (1) US20140328839A1 (ja)
EP (1) EP2773374A4 (ja)
JP (1) JP2014533246A (ja)
KR (1) KR20140097217A (ja)
CN (1) CN104039352A (ja)
AU (1) AU2012332859A1 (ja)
CA (1) CA2853858A1 (ja)
HK (2) HK1200088A1 (ja)
MX (1) MX2014004968A (ja)
RU (1) RU2014122189A (ja)
WO (1) WO2013066780A2 (ja)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6306588B2 (ja) 2012-08-21 2018-04-04 サノフィ・バイオテクノロジー Ｉｌ−４ｒアンタゴニストを投与することにより喘息を処置又は予防するための方法
TR201907907T4 (tr) * 2013-08-12 2019-06-21 Astrazeneca Ab Benralizumab kullanarak astımlı hastalarda zorlu ekspiratuar hacmi arttırma yöntemleri.
CN111588848A (zh) * 2013-08-12 2020-08-28 阿斯特拉捷利康股份公司 使用贝那利珠单抗降低哮喘恶化率的方法
RU2728578C2 (ru) 2013-08-12 2020-07-30 Астразенека Аб Способы нормализации симптомов астмы с применением бенрализумаба
BR112016008082A2 (pt) * 2013-10-15 2017-10-17 Medimmune Llc métodos para tratamento de doença pulmonar obstrutiva crônica usando benralizumab
MX2016004605A (es) * 2013-10-24 2016-11-14 Astrazeneca Ab Formulaciones de anticuerpos estables acuosas.
IL247290B (en) * 2014-02-21 2021-06-30 Sanofi Biotechnology Methods of treating or preventing asthma by adding an il-4r antagonist
CA2940295A1 (en) * 2014-02-21 2015-08-27 Sanofi Biotechnology Methods for treating or preventing asthma by administering an il-4r antagonist
MX2017006286A (es) 2014-11-14 2018-01-23 Sanofi Biotechnology Metodos para tratar sinusitis cronica con polipos nasales por administracion de un antagonista de il-4r.
US20160272706A1 (en) * 2015-01-12 2016-09-22 Medimmune Limited Il-13 binding proteins and uses thereof
JP6895884B2 (ja) * 2015-06-01 2021-06-30 国立大学法人富山大学 肺高血圧症の治療薬及び治療方法
CA3079946A1 (en) 2017-10-30 2019-05-09 Sanofi Biotechnology Methods for treating or preventing asthma by administering an il-4r antagonist
CN111100210B (zh) * 2019-01-30 2022-04-19 武汉九州钰民医药科技有限公司 一种Fc融合蛋白及其应用
TW202214692A (zh) 2020-06-05 2022-04-16 瑞典商阿斯特捷利康公司 治療患有鼻瘜肉的患者的重度氣喘之方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2233974T3 (es) * 1995-09-11 2005-06-16 Kyowa Hakko Kogyo Co., Ltd. Anticuerpo contra la cadena alfa del receptor de la interleucina 5 humana.
US6746839B1 (en) * 1998-01-12 2004-06-08 Interleukin Genetics, Inc. Diagnostics and therapeutics for an obstructive airway disease
US20050226867A1 (en) * 2003-10-08 2005-10-13 Kyowa Hakko Kogyo Co., Ltd. IL-5R-specific antibody composition
MX2020011303A (es) * 2007-05-14 2021-12-17 Astrazeneca Ab Metodos para reducir niveles de eosinofilos.

Also Published As

Publication number Publication date
EP2773374A4 (en) 2015-04-29
CA2853858A1 (en) 2013-05-10
JP2014533246A (ja) 2014-12-11
AU2012332859A1 (en) 2014-05-22
US20140328839A1 (en) 2014-11-06
HK1201440A1 (en) 2015-09-04
EP2773374A2 (en) 2014-09-10
KR20140097217A (ko) 2014-08-06
WO2013066780A3 (en) 2013-07-04
CN104039352A (zh) 2014-09-10
WO2013066780A2 (en) 2013-05-10
HK1200088A1 (en) 2015-07-31
MX2014004968A (es) 2014-08-01

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FA93 Acknowledgement of application withdrawn (no request for examination)

Effective date: 20151029