RU2014121043A - Биспецифические иммуносвязывающие средства, направленные против tnf и il-17 - Google Patents

Биспецифические иммуносвязывающие средства, направленные против tnf и il-17 Download PDF

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Publication number
RU2014121043A
RU2014121043A RU2014121043/10A RU2014121043A RU2014121043A RU 2014121043 A RU2014121043 A RU 2014121043A RU 2014121043/10 A RU2014121043/10 A RU 2014121043/10A RU 2014121043 A RU2014121043 A RU 2014121043A RU 2014121043 A RU2014121043 A RU 2014121043A
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Russia
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seq
variable domain
binding protein
cdrs
heavy chain
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RU2014121043/10A
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English (en)
Russian (ru)
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Чунг-минг ХСИЕХ
Дженнифер ПЕРЕС
Лоренцо БЕНАТУИЛ
Юлия КУЦКОВА
Джон МЕММОТТ
Сужу ЧЖУН
Лусия ИТОН
Маргарет ХЬЮГУНИН
Алисса БРИТО
Анка КЛАББЕРС
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Эббви Инк.
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Application filed by Эббви Инк. filed Critical Эббви Инк.
Publication of RU2014121043A publication Critical patent/RU2014121043A/ru

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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    • C07ORGANIC CHEMISTRY
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    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241Tumor Necrosis Factors
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    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
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    • C07K16/468Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
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    • C07K2317/00Immunoglobulins specific features
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    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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    • C07K2317/31Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
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    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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RU2014121043/10A 2011-10-24 2012-10-24 Биспецифические иммуносвязывающие средства, направленные против tnf и il-17 RU2014121043A (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161550619P 2011-10-24 2011-10-24
US61/550,619 2011-10-24
PCT/US2012/061686 WO2013063110A1 (en) 2011-10-24 2012-10-24 Bispecific immunobinders directed against tnf and il-17

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RU2014121043A true RU2014121043A (ru) 2015-12-10

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RU2014121043/10A RU2014121043A (ru) 2011-10-24 2012-10-24 Биспецифические иммуносвязывающие средства, направленные против tnf и il-17

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US (2) US9655964B2 (enExample)
EP (1) EP2771361A1 (enExample)
JP (1) JP6121432B2 (enExample)
KR (1) KR20140084254A (enExample)
CN (1) CN104185641A (enExample)
AR (1) AR088514A1 (enExample)
AU (1) AU2012328917B2 (enExample)
BR (1) BR112014009810A2 (enExample)
CA (1) CA2853114A1 (enExample)
CL (1) CL2014001055A1 (enExample)
CO (1) CO7020874A2 (enExample)
CR (1) CR20140224A (enExample)
DO (1) DOP2014000084A (enExample)
EC (1) ECSP14001260A (enExample)
GT (1) GT201400077A (enExample)
HK (1) HK1200321A1 (enExample)
IL (1) IL232207A0 (enExample)
MX (1) MX2014004980A (enExample)
PE (1) PE20142245A1 (enExample)
PH (1) PH12014500903A1 (enExample)
RS (1) RS20140202A1 (enExample)
RU (1) RU2014121043A (enExample)
SG (1) SG11201401796SA (enExample)
TW (1) TW201323441A (enExample)
UY (1) UY34410A (enExample)
WO (1) WO2013063110A1 (enExample)

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