RU2013128360A - Her2-связывающие белки, меченые 18f-содержащим кремнийорганическим соединением - Google Patents
Her2-связывающие белки, меченые 18f-содержащим кремнийорганическим соединением Download PDFInfo
- Publication number
- RU2013128360A RU2013128360A RU2013128360/10A RU2013128360A RU2013128360A RU 2013128360 A RU2013128360 A RU 2013128360A RU 2013128360/10 A RU2013128360/10 A RU 2013128360/10A RU 2013128360 A RU2013128360 A RU 2013128360A RU 2013128360 A RU2013128360 A RU 2013128360A
- Authority
- RU
- Russia
- Prior art keywords
- polypeptide
- seq
- conjugated
- reacting
- silicon fluoride
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/14—Peptides, e.g. proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/975,425 | 2010-12-22 | ||
| US12/975,425 US20120165650A1 (en) | 2010-12-22 | 2010-12-22 | Her2 binders |
| US201161438297P | 2011-02-01 | 2011-02-01 | |
| US61/438,297 | 2011-02-01 | ||
| US201161510520P | 2011-07-22 | 2011-07-22 | |
| US61/510,520 | 2011-07-22 | ||
| US201161541314P | 2011-09-30 | 2011-09-30 | |
| US61/541,314 | 2011-09-30 | ||
| PCT/US2011/065803 WO2012087912A1 (fr) | 2010-12-22 | 2011-12-19 | Peptides de liaison à her2 marqués par un composé organosilicium contenant 18f |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2013128360A true RU2013128360A (ru) | 2015-01-27 |
Family
ID=45464124
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2013128360/10A RU2013128360A (ru) | 2010-12-22 | 2011-12-19 | Her2-связывающие белки, меченые 18f-содержащим кремнийорганическим соединением |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20130295010A1 (fr) |
| EP (1) | EP2661284A1 (fr) |
| JP (1) | JP2014503547A (fr) |
| KR (1) | KR20130132939A (fr) |
| CN (1) | CN103402550B (fr) |
| AU (1) | AU2011349486A1 (fr) |
| BR (1) | BR112013015798A2 (fr) |
| CA (1) | CA2822698A1 (fr) |
| MX (1) | MX2013007363A (fr) |
| NZ (1) | NZ612327A (fr) |
| RU (1) | RU2013128360A (fr) |
| SG (1) | SG191338A1 (fr) |
| WO (1) | WO2012087912A1 (fr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120165650A1 (en) | 2010-12-22 | 2012-06-28 | General Electric Company | Her2 binders |
| MX2013007365A (es) * | 2010-12-22 | 2013-09-26 | Ge Healthcare Ltd | Péptidos de enlace her2 etiquetados con fluoruro de aluminio- [18] combinados mediante nota. |
| GB201209082D0 (en) * | 2012-05-24 | 2012-07-04 | Ge Healthcare Ltd | Purification method |
| BR112015032211A2 (pt) | 2013-06-27 | 2017-08-29 | Ge Healthcare Ltd | Método para monitorar resposta à inibição de hsp90, e, uso de um polipeptídeo isolado conjugado com 18f |
| GB201314936D0 (en) | 2013-08-21 | 2013-10-02 | Ge Healthcare Ltd | Radiolabelling method |
| GB201322456D0 (en) | 2013-12-18 | 2014-02-05 | Ge Healthcare Ltd | Radiotracer compositions and methods |
| GB201322451D0 (en) * | 2013-12-18 | 2014-02-05 | Ge Healthcare Ltd | Purification method and compositions |
| FI3917626T3 (fi) * | 2019-01-30 | 2023-08-17 | Univ Muenchen Tech | Psma:ta sitova kaksimuotoinen radiomerkkiaine ja terapeuttinen aine |
| CN110251695B (zh) * | 2019-07-10 | 2021-12-21 | 莎穆(上海)生物科技有限公司 | 一种靶向her2的放射性配合物及其制备方法和应用 |
| CN114317385B (zh) * | 2021-11-11 | 2024-02-13 | 元本(珠海横琴)生物科技有限公司 | 一种促进her2亲和体蛋白分泌表达的发酵培养基及发酵工艺 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0305704D0 (en) | 2003-03-13 | 2003-04-16 | Amersham Plc | Radiofluorination methods |
| DE602004018141D1 (de) * | 2003-07-04 | 2009-01-15 | Affibody Ab | Polypeptide mit bindungsaffinität für her2 |
| GB0428012D0 (en) | 2004-12-22 | 2005-01-26 | Hammersmith Imanet Ltd | Radiolabelling methods |
| WO2008049866A1 (fr) * | 2006-10-27 | 2008-05-02 | Affibody Ab | Nouveau composé chélateur |
| WO2008118601A2 (fr) * | 2007-02-27 | 2008-10-02 | Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Molécules d'anticorps radiomarqué |
| EP2072525A1 (fr) * | 2007-12-21 | 2009-06-24 | Affibody AB | Nouveaux polypeptides présentant une affinité de liaison pour HER2 |
-
2011
- 2011-12-19 AU AU2011349486A patent/AU2011349486A1/en not_active Abandoned
- 2011-12-19 WO PCT/US2011/065803 patent/WO2012087912A1/fr active Application Filing
- 2011-12-19 US US13/996,142 patent/US20130295010A1/en not_active Abandoned
- 2011-12-19 CA CA2822698A patent/CA2822698A1/fr not_active Abandoned
- 2011-12-19 NZ NZ61232711A patent/NZ612327A/en not_active IP Right Cessation
- 2011-12-19 JP JP2013546280A patent/JP2014503547A/ja active Pending
- 2011-12-19 EP EP11805725.6A patent/EP2661284A1/fr not_active Withdrawn
- 2011-12-19 MX MX2013007363A patent/MX2013007363A/es unknown
- 2011-12-19 KR KR1020137019120A patent/KR20130132939A/ko not_active Application Discontinuation
- 2011-12-19 SG SG2013048830A patent/SG191338A1/en unknown
- 2011-12-19 RU RU2013128360/10A patent/RU2013128360A/ru not_active Application Discontinuation
- 2011-12-19 CN CN201180068115.9A patent/CN103402550B/zh not_active Expired - Fee Related
- 2011-12-19 BR BR112013015798A patent/BR112013015798A2/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US20130295010A1 (en) | 2013-11-07 |
| EP2661284A1 (fr) | 2013-11-13 |
| AU2011349486A1 (en) | 2013-07-25 |
| CA2822698A1 (fr) | 2012-06-28 |
| CN103402550A (zh) | 2013-11-20 |
| NZ612327A (en) | 2015-03-27 |
| JP2014503547A (ja) | 2014-02-13 |
| SG191338A1 (en) | 2013-07-31 |
| BR112013015798A2 (pt) | 2019-09-24 |
| WO2012087912A1 (fr) | 2012-06-28 |
| CN103402550B (zh) | 2015-12-09 |
| MX2013007363A (es) | 2013-09-26 |
| KR20130132939A (ko) | 2013-12-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20160603 |