RU2012137304A - Рекомбинантные белки для применения в вакцине, антитела к указанным белкам и диагностические и терапевтические способы, включающие указанное - Google Patents
Рекомбинантные белки для применения в вакцине, антитела к указанным белкам и диагностические и терапевтические способы, включающие указанное Download PDFInfo
- Publication number
- RU2012137304A RU2012137304A RU2012137304/10A RU2012137304A RU2012137304A RU 2012137304 A RU2012137304 A RU 2012137304A RU 2012137304/10 A RU2012137304/10 A RU 2012137304/10A RU 2012137304 A RU2012137304 A RU 2012137304A RU 2012137304 A RU2012137304 A RU 2012137304A
- Authority
- RU
- Russia
- Prior art keywords
- seq
- protein
- fragment
- derivative
- antibodies
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title claims abstract 36
- 108090000623 proteins and genes Proteins 0.000 title claims abstract 36
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 title 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 title 1
- 238000002405 diagnostic procedure Methods 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
- 239000012634 fragment Substances 0.000 claims abstract 22
- 241000589886 Treponema Species 0.000 claims abstract 16
- 238000000034 method Methods 0.000 claims abstract 13
- 201000010099 disease Diseases 0.000 claims abstract 11
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims abstract 11
- 230000028993 immune response Effects 0.000 claims abstract 11
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims abstract 10
- 125000003275 alpha amino acid group Chemical group 0.000 claims abstract 10
- 230000001939 inductive effect Effects 0.000 claims abstract 6
- 201000004624 Dermatitis Diseases 0.000 claims abstract 4
- 238000001514 detection method Methods 0.000 claims abstract 3
- 208000006413 Digital Dermatitis Diseases 0.000 claims abstract 2
- 239000002671 adjuvant Substances 0.000 claims abstract 2
- 239000000969 carrier Substances 0.000 claims abstract 2
- 208000023867 digital dermatitis in cattle Diseases 0.000 claims abstract 2
- 239000003085 diluting agent Substances 0.000 claims abstract 2
- 239000003814 drug Substances 0.000 claims abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 claims abstract 2
- 230000002265 prevention Effects 0.000 claims abstract 2
- 102000039446 nucleic acids Human genes 0.000 claims 3
- 108020004707 nucleic acids Proteins 0.000 claims 3
- 150000007523 nucleic acids Chemical class 0.000 claims 3
- 239000007790 solid phase Substances 0.000 claims 2
- 239000013060 biological fluid Substances 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 230000001105 regulatory effect Effects 0.000 claims 1
- 238000000926 separation method Methods 0.000 claims 1
- 230000009261 transgenic effect Effects 0.000 claims 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/0225—Spirochetes, e.g. Treponema, Leptospira, Borrelia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/20—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Spirochaetales (O), e.g. Treponema, Leptospira
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29896010P | 2010-01-28 | 2010-01-28 | |
| US61/298,960 | 2010-01-28 | ||
| US36098610P | 2010-07-02 | 2010-07-02 | |
| US61/360,986 | 2010-07-02 | ||
| PCT/SE2011/050090 WO2011093783A1 (en) | 2010-01-28 | 2011-01-28 | Recombinant proteins for use in vaccine, antibodies against said proteins, and diagnostic and therapeutic methods including the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2012137304A true RU2012137304A (ru) | 2014-03-10 |
Family
ID=44319584
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2012137304/10A RU2012137304A (ru) | 2010-01-28 | 2011-01-28 | Рекомбинантные белки для применения в вакцине, антитела к указанным белкам и диагностические и терапевтические способы, включающие указанное |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US8703432B2 (enExample) |
| EP (1) | EP2528939B1 (enExample) |
| JP (1) | JP2013518563A (enExample) |
| CN (1) | CN102918053A (enExample) |
| AU (1) | AU2011209988A1 (enExample) |
| BR (1) | BR112012018840A2 (enExample) |
| CA (1) | CA2825282A1 (enExample) |
| NZ (1) | NZ601980A (enExample) |
| RU (1) | RU2012137304A (enExample) |
| WO (1) | WO2011093783A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10010423B2 (en) | 2013-03-15 | 2018-07-03 | Avinash Kumar | Anatomical humeral fixation system and method |
| JP5740062B1 (ja) | 2013-07-03 | 2015-06-24 | 三菱化学フーズ株式会社 | 毛状疣贅病の予防および／または治療方法 |
| US10022458B2 (en) | 2015-03-05 | 2018-07-17 | Iowa State University Research Foundation, Inc. | Animal model protocol, diagnostic, therapeutic and vaccine against digital dermatitis |
| MX2020005104A (es) * | 2017-11-17 | 2020-12-10 | Hipra Scient S L U | Composiciones de vacuna para uso contra dermatitis digital en un mamifero. |
| KR102177180B1 (ko) * | 2020-05-13 | 2020-11-10 | 순천대학교 산학협력단 | 신규 트레포네마 파지데니스 균주 및 이의 분리 방법 |
| KR102177181B1 (ko) * | 2020-05-14 | 2020-11-10 | 순천대학교 산학협력단 | 트레포네마 파지데니스 균주의 배양 조성물 및 이의 용도 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0534526A1 (en) * | 1991-09-25 | 1993-03-31 | Duphar International Research B.V | Treponema hyodysenteriae vaccine |
| IL103530A0 (en) * | 1991-10-25 | 1993-03-15 | Duphar Int Res | Treponema hyodysenteriae vaccine |
| US6287575B1 (en) | 1997-10-03 | 2001-09-11 | The Regents Of The University Of California | Vaccine against papillomatous digital dermatitis (PDD) |
| US6096323A (en) * | 1997-10-03 | 2000-08-01 | The Regents Of The University Of California | Vaccine against papillomatous digital dermatitis (PDD) |
-
2011
- 2011-01-28 US US13/576,032 patent/US8703432B2/en not_active Expired - Fee Related
- 2011-01-28 NZ NZ601980A patent/NZ601980A/en not_active IP Right Cessation
- 2011-01-28 RU RU2012137304/10A patent/RU2012137304A/ru not_active Application Discontinuation
- 2011-01-28 CN CN2011800077474A patent/CN102918053A/zh active Pending
- 2011-01-28 AU AU2011209988A patent/AU2011209988A1/en not_active Abandoned
- 2011-01-28 WO PCT/SE2011/050090 patent/WO2011093783A1/en not_active Ceased
- 2011-01-28 BR BR112012018840A patent/BR112012018840A2/pt not_active IP Right Cessation
- 2011-01-28 CA CA2825282A patent/CA2825282A1/en not_active Abandoned
- 2011-01-28 JP JP2012551129A patent/JP2013518563A/ja active Pending
- 2011-01-28 EP EP11737369.6A patent/EP2528939B1/en not_active Not-in-force
Also Published As
| Publication number | Publication date |
|---|---|
| CA2825282A1 (en) | 2011-08-04 |
| EP2528939B1 (en) | 2015-04-08 |
| US20130034560A1 (en) | 2013-02-07 |
| EP2528939A1 (en) | 2012-12-05 |
| JP2013518563A (ja) | 2013-05-23 |
| EP2528939A4 (en) | 2013-07-03 |
| CN102918053A (zh) | 2013-02-06 |
| NZ601980A (en) | 2014-08-29 |
| BR112012018840A2 (pt) | 2017-06-20 |
| US8703432B2 (en) | 2014-04-22 |
| WO2011093783A1 (en) | 2011-08-04 |
| AU2011209988A1 (en) | 2012-09-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20150903 |