RU2012107993A - Полипептиды porhyromonas gingivalis - Google Patents
Полипептиды porhyromonas gingivalis Download PDFInfo
- Publication number
- RU2012107993A RU2012107993A RU2012107993/10A RU2012107993A RU2012107993A RU 2012107993 A RU2012107993 A RU 2012107993A RU 2012107993/10 A RU2012107993/10 A RU 2012107993/10A RU 2012107993 A RU2012107993 A RU 2012107993A RU 2012107993 A RU2012107993 A RU 2012107993A
- Authority
- RU
- Russia
- Prior art keywords
- polypeptide
- seq
- identity
- variant
- immunogenic fragment
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title claims abstract 80
- 102000004196 processed proteins & peptides Human genes 0.000 title claims abstract 80
- 108090000765 processed proteins & peptides Proteins 0.000 title claims abstract 80
- 230000002163 immunogen Effects 0.000 claims abstract 56
- 239000012634 fragment Substances 0.000 claims abstract 50
- 102000004169 proteins and genes Human genes 0.000 claims abstract 50
- 108090000623 proteins and genes Proteins 0.000 claims abstract 50
- 241000605862 Porphyromonas gingivalis Species 0.000 claims abstract 41
- 239000002671 adjuvant Substances 0.000 claims abstract 4
- 239000003937 drug carrier Substances 0.000 claims abstract 4
- 208000015181 infectious disease Diseases 0.000 claims 13
- 238000000034 method Methods 0.000 claims 13
- 102000039446 nucleic acids Human genes 0.000 claims 12
- 108020004707 nucleic acids Proteins 0.000 claims 12
- 150000007523 nucleic acids Chemical class 0.000 claims 12
- 208000024891 symptom Diseases 0.000 claims 3
- 230000002265 prevention Effects 0.000 claims 2
- 230000028993 immune response Effects 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/56955—Bacteria involved in periodontal diseases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/0216—Bacteriodetes, e.g. Bacteroides, Ornithobacter, Porphyromonas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1257—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Bacteridaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
- G01N2333/21—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Pseudomonadaceae (F)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Mycology (AREA)
- Genetics & Genomics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23071709P | 2009-08-02 | 2009-08-02 | |
| US61/230,717 | 2009-08-02 | ||
| PCT/CA2010/001177 WO2011014947A1 (en) | 2009-08-02 | 2010-07-30 | Porphyromonas gingivalis polypeptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2012107993A true RU2012107993A (ru) | 2013-09-10 |
Family
ID=43543841
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2012107993/10A RU2012107993A (ru) | 2009-08-02 | 2010-07-30 | Полипептиды porhyromonas gingivalis |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US9366673B2 (OSRAM) |
| EP (1) | EP2462160A4 (OSRAM) |
| JP (2) | JP5876411B2 (OSRAM) |
| KR (1) | KR20120050469A (OSRAM) |
| CN (1) | CN102712693A (OSRAM) |
| AR (1) | AR085167A1 (OSRAM) |
| AU (1) | AU2010281313B2 (OSRAM) |
| BR (1) | BR112012002429A2 (OSRAM) |
| CA (1) | CA2769231A1 (OSRAM) |
| IL (1) | IL217861A0 (OSRAM) |
| MX (1) | MX2012001495A (OSRAM) |
| RU (1) | RU2012107993A (OSRAM) |
| WO (1) | WO2011014947A1 (OSRAM) |
| ZA (1) | ZA201200799B (OSRAM) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8871213B2 (en) | 2008-08-29 | 2014-10-28 | Oral Health Australia Pty Ltd | Prevention, treatment and diagnosis of P. gingivalis infection |
| MY162557A (en) * | 2010-02-26 | 2017-06-15 | Oral Health Australia Pty Ltd | Treatment or prevention of infection |
| CA2894903A1 (en) * | 2012-12-14 | 2014-06-19 | Sanofi Pasteur, Ltd. | Methods for assessing immunogenicity |
| EP3303385A2 (en) * | 2015-05-27 | 2018-04-11 | Merial, Inc. | Compositions containing antimicrobial igy antibodies, for treatment and prevention of disorders and diseases caused by oral health compromising (ohc) microorganisms |
| US10835590B2 (en) | 2017-10-12 | 2020-11-17 | Vaxcyte, Inc. | Periodontitis vaccine and related compositions and methods of use |
| IL312717A (en) * | 2021-11-17 | 2024-07-01 | Nerd Bio Llc | Systems and methods for real-time cellular engagement with DRUG-TARGET |
| CN114469863B (zh) * | 2021-11-26 | 2023-09-26 | 南方医科大学南方医院 | 甾醇脂质体作为牙髓和牙本质药物传递系统的应用 |
| CN116474096A (zh) * | 2022-01-14 | 2023-07-25 | 中山大学附属口腔医院 | 靶向牙龈卟啉单胞菌RgpB在结直肠癌的治疗及预防中的应用 |
| CA3250494A1 (en) * | 2022-04-26 | 2023-11-02 | Keystone Bio Inc | FORMULATION FOR ANTIGEN-BINDING MOLECULES THAT BIND TO PORPHYROMONAS GINGIVALIS |
| AU2022477921A1 (en) * | 2022-09-16 | 2025-04-24 | Qjm Bioinformation Ltd | Antibodies and method of use for p. gingivalis |
| AR133317A1 (es) | 2023-07-19 | 2025-09-17 | Sanofi Sa | Constructos antigénicos de porphyromonas gingivalis |
| CN116751292B (zh) * | 2023-07-31 | 2024-05-14 | 河南大学 | 牙龈卟啉单胞菌Mfa1单克隆抗体及其应用 |
| CN119424610A (zh) * | 2024-12-05 | 2025-02-14 | 重庆师范大学 | 具备抗衰老活性的重组蛋白制剂及其制备方法、应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU742668B2 (en) * | 1996-03-22 | 2002-01-10 | Morehouse School Of Medicine | Immunogenic compositions comprising porphyromonas gingivalis peptides and methods |
| AUPN901296A0 (en) * | 1996-03-29 | 1996-04-26 | University Of Melbourne, The | Porphyromonas gingivalis antigens for the diagnosis and treatment of periodontitis |
| EP2264176A1 (en) * | 1997-12-10 | 2010-12-22 | CSL Limited | Porphorymonas gingivalis polypeptides and polynucleotides |
| JP2003192616A (ja) * | 2001-12-27 | 2003-07-09 | Univ Nihon | 歯周病用ｄｎａワクチン |
| JP2003286191A (ja) * | 2002-03-27 | 2003-10-07 | Univ Nihon | 歯周病用粘膜免疫ワクチン |
| WO2004083425A1 (ja) * | 2003-03-17 | 2004-09-30 | Kirin Beer Kabushiki Kaisha | 歯周病治療剤 |
| JP2005179301A (ja) * | 2003-12-22 | 2005-07-07 | Univ Nihon | 歯周病用経皮免疫ワクチン |
| CA2652957A1 (en) | 2006-06-27 | 2008-01-03 | Oral Health Australia Pty Ltd. | Porphyromonas gingivalis polypeptides useful in the prevention of periodontal disease |
| EP2604692A1 (en) * | 2007-07-12 | 2013-06-19 | Oral Health Australia Pty Ltd | Immunology treatment for biofilms |
-
2010
- 2010-07-30 RU RU2012107993/10A patent/RU2012107993A/ru not_active Application Discontinuation
- 2010-07-30 CN CN2010800451190A patent/CN102712693A/zh active Pending
- 2010-07-30 EP EP10805906.4A patent/EP2462160A4/en not_active Withdrawn
- 2010-07-30 MX MX2012001495A patent/MX2012001495A/es unknown
- 2010-07-30 KR KR1020127005748A patent/KR20120050469A/ko not_active Ceased
- 2010-07-30 WO PCT/CA2010/001177 patent/WO2011014947A1/en not_active Ceased
- 2010-07-30 JP JP2012523169A patent/JP5876411B2/ja not_active Expired - Fee Related
- 2010-07-30 CA CA2769231A patent/CA2769231A1/en not_active Abandoned
- 2010-07-30 US US13/388,042 patent/US9366673B2/en not_active Expired - Fee Related
- 2010-07-30 BR BR112012002429A patent/BR112012002429A2/pt active Search and Examination
- 2010-07-30 AU AU2010281313A patent/AU2010281313B2/en not_active Ceased
- 2010-08-03 AR ARP100102836A patent/AR085167A1/es unknown
-
2012
- 2012-01-31 IL IL217861A patent/IL217861A0/en unknown
- 2012-02-01 ZA ZA2012/00799A patent/ZA201200799B/en unknown
-
2015
- 2015-07-02 JP JP2015133497A patent/JP2015178533A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2010281313A1 (en) | 2012-03-08 |
| KR20120050469A (ko) | 2012-05-18 |
| AR085167A1 (es) | 2013-09-18 |
| CN102712693A (zh) | 2012-10-03 |
| AU2010281313B2 (en) | 2015-09-03 |
| JP5876411B2 (ja) | 2016-03-02 |
| EP2462160A4 (en) | 2013-04-24 |
| CA2769231A1 (en) | 2011-02-10 |
| EP2462160A1 (en) | 2012-06-13 |
| JP2013501007A (ja) | 2013-01-10 |
| ZA201200799B (en) | 2013-06-26 |
| MX2012001495A (es) | 2012-08-03 |
| JP2015178533A (ja) | 2015-10-08 |
| US9366673B2 (en) | 2016-06-14 |
| IL217861A0 (en) | 2012-03-29 |
| WO2011014947A1 (en) | 2011-02-10 |
| BR112012002429A2 (pt) | 2016-11-08 |
| US20120156211A1 (en) | 2012-06-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA94 | Acknowledgement of application withdrawn (non-payment of fees) |
Effective date: 20170111 |