RU2011134486A - Агент, повышающий экспрессию редокс-факторов - Google Patents
Агент, повышающий экспрессию редокс-факторов Download PDFInfo
- Publication number
- RU2011134486A RU2011134486A RU2011134486/15A RU2011134486A RU2011134486A RU 2011134486 A RU2011134486 A RU 2011134486A RU 2011134486/15 A RU2011134486/15 A RU 2011134486/15A RU 2011134486 A RU2011134486 A RU 2011134486A RU 2011134486 A RU2011134486 A RU 2011134486A
- Authority
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- Russia
- Prior art keywords
- redox
- thioredoxin
- expression
- redox factor
- agent
- Prior art date
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- 102000017278 Glutaredoxin Human genes 0.000 claims abstract 4
- 108050005205 Glutaredoxin Proteins 0.000 claims abstract 4
- 244000062241 Kaempferia galanga Species 0.000 claims abstract 4
- 235000013421 Kaempferia galanga Nutrition 0.000 claims abstract 4
- REFJWTPEDVJJIY-UHFFFAOYSA-N Quercetin Chemical compound C=1C(O)=CC(O)=C(C(C=2O)=O)C=1OC=2C1=CC=C(O)C(O)=C1 REFJWTPEDVJJIY-UHFFFAOYSA-N 0.000 claims abstract 4
- 102000002933 Thioredoxin Human genes 0.000 claims abstract 4
- 102100032506 Thioredoxin reductase 3 Human genes 0.000 claims abstract 4
- 102000013090 Thioredoxin-Disulfide Reductase Human genes 0.000 claims abstract 4
- 108010079911 Thioredoxin-disulfide reductase Proteins 0.000 claims abstract 4
- 239000004480 active ingredient Substances 0.000 claims abstract 4
- 239000000126 substance Substances 0.000 claims abstract 4
- 108060008226 thioredoxin Proteins 0.000 claims abstract 4
- 229940094937 thioredoxin Drugs 0.000 claims abstract 4
- 108010074309 thioredoxin glutathione reductase Proteins 0.000 claims abstract 4
- 235000011201 Ginkgo Nutrition 0.000 claims abstract 2
- 235000008100 Ginkgo biloba Nutrition 0.000 claims abstract 2
- 244000194101 Ginkgo biloba Species 0.000 claims abstract 2
- ZVOLCUVKHLEPEV-UHFFFAOYSA-N Quercetagetin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=C(O)C(O)=C(O)C=C2O1 ZVOLCUVKHLEPEV-UHFFFAOYSA-N 0.000 claims abstract 2
- HWTZYBCRDDUBJY-UHFFFAOYSA-N Rhynchosin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=CC(O)=C(O)C=C2O1 HWTZYBCRDDUBJY-UHFFFAOYSA-N 0.000 claims abstract 2
- 229930182470 glycoside Natural products 0.000 claims abstract 2
- 150000002338 glycosides Chemical class 0.000 claims abstract 2
- IYRMWMYZSQPJKC-UHFFFAOYSA-N kaempferol Chemical compound C1=CC(O)=CC=C1C1=C(O)C(=O)C2=C(O)C=C(O)C=C2O1 IYRMWMYZSQPJKC-UHFFFAOYSA-N 0.000 claims abstract 2
- MWDZOUNAPSSOEL-UHFFFAOYSA-N kaempferol Natural products OC1=C(C(=O)c2cc(O)cc(O)c2O1)c3ccc(O)cc3 MWDZOUNAPSSOEL-UHFFFAOYSA-N 0.000 claims abstract 2
- 229960001285 quercetin Drugs 0.000 claims abstract 2
- 235000005875 quercetin Nutrition 0.000 claims abstract 2
- 230000002708 enhancing effect Effects 0.000 abstract 1
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/18—Antioxidants, e.g. antiradicals
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- A61P27/14—Decongestants or antiallergics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P39/06—Free radical scavengers or antioxidants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P7/10—Antioedematous agents; Diuretics
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- A—HUMAN NECESSITIES
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P9/12—Antihypertensives
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Mycology (AREA)
- Alternative & Traditional Medicine (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
Abstract
1. Агент, повышающий экспрессию редокс-фактора, который содержит в качестве активного ингредиента кемпферол, кверцетин, их гликозиды или любые их комбинации.2. Агент, повышающий экспрессию редокс-фактора по п.1, в котором редокс-фактор представляет собой одно или более веществ, выбранных из группы, состоящей из тиоредоксина, тиоредоксинредуктазы, глутатионредуктазы и глутаредоксина.3. Агент, повышающий экспрессию редокс-фактора, который в качестве активного ингредиента содержит экстракт из листьев гинкго, экстракт галанги (Kaempferia galanga) или любые их комбинации.4. Агент, повышающий экспрессию редокс-фактора по п.3, в котором редокс-фактор представляет собой одно или более веществ, выбранных из группы, состоящей из тиоредоксина, тиоредоксинредуктазы, глутатионредуктазы и глутаредоксина.
Claims (4)
1. Агент, повышающий экспрессию редокс-фактора, который содержит в качестве активного ингредиента кемпферол, кверцетин, их гликозиды или любые их комбинации.
2. Агент, повышающий экспрессию редокс-фактора по п.1, в котором редокс-фактор представляет собой одно или более веществ, выбранных из группы, состоящей из тиоредоксина, тиоредоксинредуктазы, глутатионредуктазы и глутаредоксина.
3. Агент, повышающий экспрессию редокс-фактора, который в качестве активного ингредиента содержит экстракт из листьев гинкго, экстракт галанги (Kaempferia galanga) или любые их комбинации.
4. Агент, повышающий экспрессию редокс-фактора по п.3, в котором редокс-фактор представляет собой одно или более веществ, выбранных из группы, состоящей из тиоредоксина, тиоредоксинредуктазы, глутатионредуктазы и глутаредоксина.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29958910P | 2010-01-29 | 2010-01-29 | |
US61/299,589 | 2010-01-29 | ||
PCT/JP2011/051811 WO2011093469A1 (ja) | 2010-01-29 | 2011-01-28 | レドックス関連因子発現促進剤 |
Publications (2)
Publication Number | Publication Date |
---|---|
RU2011134486A true RU2011134486A (ru) | 2013-02-27 |
RU2606856C2 RU2606856C2 (ru) | 2017-01-10 |
Family
ID=44319447
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2011134486A RU2606856C2 (ru) | 2010-01-29 | 2011-01-28 | Агент, повышающий экспрессию редокс-факторов |
Country Status (9)
Country | Link |
---|---|
US (1) | US20110189318A1 (ru) |
EP (1) | EP2529736A4 (ru) |
JP (1) | JP5833438B2 (ru) |
KR (1) | KR20120119976A (ru) |
CN (1) | CN102361637A (ru) |
BR (1) | BRPI1100012A2 (ru) |
RU (1) | RU2606856C2 (ru) |
TW (1) | TWI572353B (ru) |
WO (1) | WO2011093469A1 (ru) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
LU91412B1 (en) * | 2008-01-30 | 2009-07-31 | Wurth Paul Sa | Charging device for distributing bulk material |
JP2016006021A (ja) * | 2014-06-20 | 2016-01-14 | 株式会社ノエビア | チオレドキシン関連因子発現促進剤 |
JP2016088905A (ja) * | 2014-11-07 | 2016-05-23 | 健治 椛島 | 上皮又は粘膜に投与される組成物 |
WO2016132483A1 (ja) * | 2015-02-18 | 2016-08-25 | 学校法人福岡大学 | ヒトキマーゼ阻害剤及びヒトキマーゼの活性が関与する疾患の予防治療用薬剤 |
JPWO2022075096A1 (ru) * | 2020-10-07 | 2022-04-14 | ||
JP6860739B1 (ja) * | 2020-11-20 | 2021-04-21 | ジェイ−ネットワーク,インコーポレイテッド | 表皮内の抗酸化物質の発現増強剤 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0769862A (ja) * | 1993-09-01 | 1995-03-14 | Kao Corp | 入浴剤組成物 |
JP3578858B2 (ja) | 1995-12-11 | 2004-10-20 | 株式会社ノエビア | 皮膚外用剤 |
US6471972B1 (en) * | 1996-11-07 | 2002-10-29 | Lvmh Recherche | Cosmetic treatment method for fighting against skin ageing effects |
US20040043047A1 (en) * | 1999-03-26 | 2004-03-04 | Parfums Christian Dior | Cosmetic or dermatological compositions containing at least one substance for increasing the functionality and/or expression of the CD44 membrane receptors of skin cells |
US20040101578A1 (en) * | 2001-08-03 | 2004-05-27 | Min-Young Kim | Compositon containg ginkgo biloba that inhibit angiogenesis and matrix metalloprotinase |
JP2007510725A (ja) * | 2003-11-05 | 2007-04-26 | オステオスクリーン,インコーポレイテッド | イチョウフラバノイド類による発毛の刺激 |
JPWO2006033351A1 (ja) | 2004-09-22 | 2008-05-15 | レドックス・バイオサイエンス株式会社 | チオレドキシン発現誘導用組成物 |
KR20060080376A (ko) * | 2005-01-05 | 2006-07-10 | 하수용 | 무기 광물 용해액 및 식물 추출물을 포함하는 화장료조성물 및 그의 제조 방법 |
US20060165812A1 (en) * | 2005-01-21 | 2006-07-27 | Amershire Investment Corporation | Method and topical formulation for treating headaches |
KR100665966B1 (ko) * | 2005-09-23 | 2007-01-09 | 장정만 | 규산염과 은행잎추출물로 제조되는 입욕제의 조성물 및제조제법 |
JP2007284430A (ja) | 2006-03-20 | 2007-11-01 | Rohto Pharmaceut Co Ltd | グルタチオン産生促進剤 |
JP2007269671A (ja) | 2006-03-30 | 2007-10-18 | Redox Bioscience Inc | アレルギー性皮膚炎の予防ないし治療剤 |
KR100892273B1 (ko) * | 2007-04-25 | 2009-04-09 | (주)아모레퍼시픽 | 캄페롤-3-o-루티노사이드를 유효 성분으로 함유하는 피부외용제 조성물 |
JP2009132662A (ja) * | 2007-11-30 | 2009-06-18 | Maruzen Pharmaceut Co Ltd | グルタチオン産生促進剤 |
-
2010
- 2010-12-28 US US12/980,051 patent/US20110189318A1/en not_active Abandoned
-
2011
- 2011-01-28 EP EP11737179.9A patent/EP2529736A4/en not_active Withdrawn
- 2011-01-28 BR BRPI1100012A patent/BRPI1100012A2/pt not_active IP Right Cessation
- 2011-01-28 WO PCT/JP2011/051811 patent/WO2011093469A1/ja active Application Filing
- 2011-01-28 RU RU2011134486A patent/RU2606856C2/ru not_active IP Right Cessation
- 2011-01-28 KR KR1020117006205A patent/KR20120119976A/ko not_active Application Discontinuation
- 2011-01-28 CN CN2011800001278A patent/CN102361637A/zh active Pending
- 2011-01-28 TW TW100103496A patent/TWI572353B/zh active
- 2011-01-28 JP JP2011507745A patent/JP5833438B2/ja active Active
Also Published As
Publication number | Publication date |
---|---|
CN102361637A (zh) | 2012-02-22 |
TW201136587A (en) | 2011-11-01 |
TWI572353B (zh) | 2017-03-01 |
US20110189318A1 (en) | 2011-08-04 |
JP5833438B2 (ja) | 2015-12-16 |
KR20120119976A (ko) | 2012-11-01 |
WO2011093469A1 (ja) | 2011-08-04 |
EP2529736A1 (en) | 2012-12-05 |
BRPI1100012A2 (pt) | 2016-05-03 |
EP2529736A4 (en) | 2013-07-10 |
JPWO2011093469A1 (ja) | 2013-06-06 |
RU2606856C2 (ru) | 2017-01-10 |
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