ECSP088745A - Derivados sustituidos de cromanol y su uso - Google Patents
Derivados sustituidos de cromanol y su usoInfo
- Publication number
- ECSP088745A ECSP088745A EC2008008745A ECSP088745A ECSP088745A EC SP088745 A ECSP088745 A EC SP088745A EC 2008008745 A EC2008008745 A EC 2008008745A EC SP088745 A ECSP088745 A EC SP088745A EC SP088745 A ECSP088745 A EC SP088745A
- Authority
- EC
- Ecuador
- Prior art keywords
- chromanol
- substituted derivatives
- prevention
- treatment
- diseases
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/96—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings spiro-condensed with carbocyclic rings or ring systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Child & Adolescent Psychology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La presente invención se refiere a derivados sustituidos de cromanol, a procedimientos para su preparación, a su uso solos o combinados para el tratamiento y/o la prevención de enfermedades, así como a su uso para preparar medicamentos para el tratamiento y/o la prevención de enfermedades, en especial para el tratamiento y/o la prevención de enfermedades cardiovasculares.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102006012548A DE102006012548A1 (de) | 2006-03-18 | 2006-03-18 | Substituierte Chromanol-Derivate und ihre Verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP088745A true ECSP088745A (es) | 2008-10-31 |
Family
ID=38162293
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EC2008008745A ECSP088745A (es) | 2006-03-18 | 2008-09-18 | Derivados sustituidos de cromanol y su uso |
Country Status (21)
Country | Link |
---|---|
US (1) | US8227511B2 (es) |
EP (1) | EP1999123A1 (es) |
JP (1) | JP5285594B2 (es) |
KR (1) | KR101440633B1 (es) |
CN (1) | CN101443321B (es) |
AR (1) | AR059831A1 (es) |
AU (1) | AU2007229092A1 (es) |
BR (1) | BRPI0708851A2 (es) |
CA (1) | CA2645884A1 (es) |
CR (1) | CR10305A (es) |
DE (1) | DE102006012548A1 (es) |
DO (1) | DOP2007000043A (es) |
EC (1) | ECSP088745A (es) |
HK (1) | HK1132731A1 (es) |
MX (1) | MX2008011893A (es) |
PE (1) | PE20080005A1 (es) |
RU (1) | RU2459817C2 (es) |
TW (1) | TW200812998A (es) |
UY (1) | UY30215A1 (es) |
WO (1) | WO2007107243A1 (es) |
ZA (1) | ZA200807809B (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2025674A1 (de) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
MX2010005704A (es) * | 2007-12-18 | 2010-08-17 | Glenmark Pharmaceuticals Sa | Derivados de cromano como modulares del trpv3. |
WO2011072064A1 (en) | 2009-12-08 | 2011-06-16 | Array Biopharma Inc. | S piro [chroman - 4, 4 ' - imidazol] ones as beta - secretase inhibitors |
WO2011157827A1 (de) | 2010-06-18 | 2011-12-22 | Sanofi | Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen |
EP2683705B1 (de) | 2011-03-08 | 2015-04-22 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
US8828995B2 (en) | 2011-03-08 | 2014-09-09 | Sanofi | Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
EP2683700B1 (de) | 2011-03-08 | 2015-02-18 | Sanofi | Tetrasubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
WO2012120055A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung |
WO2012120052A1 (de) | 2011-03-08 | 2012-09-13 | Sanofi | Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung |
EP3191441B1 (en) * | 2014-09-09 | 2020-02-19 | Boehringer Ingelheim International Trading (Shanghai) Co. Ltd. | Novel process for preparation of spiro[2.5]octane-5,7-dione and spiro[3.5]nonane-6,8-dione |
CN105501108B (zh) | 2014-10-08 | 2020-07-07 | 福特全球技术公司 | 具有点亮的车轮总成的车辆照明系统 |
CN105546443B (zh) | 2014-10-27 | 2019-10-18 | 福特全球技术公司 | 具有照明的排气装置的车辆照明系统 |
CN112326830A (zh) * | 2020-11-03 | 2021-02-05 | 湖南迪诺制药股份有限公司 | 一种阿托伐他汀钙异构体的检测方法 |
BR112023020381A2 (pt) | 2021-05-12 | 2023-11-21 | Boehringer Ingelheim Int | Derivados de piridina com substituintes cíclicos ligados por c como inibidores de cgas |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19610932A1 (de) | 1996-03-20 | 1997-09-25 | Bayer Ag | 2-Aryl-substituierte Pyridine |
DE19619614A1 (de) * | 1996-05-15 | 1997-11-20 | Hoechst Ag | Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
DE19627431A1 (de) * | 1996-07-08 | 1998-01-15 | Bayer Ag | Heterocyclisch kondensierte Pyridine |
US6207671B1 (en) | 1996-07-08 | 2001-03-27 | Bayer Aktiengesellschaft | Cycloalkano-pyridines |
HRP970330B1 (en) | 1996-07-08 | 2004-06-30 | Bayer Ag | Cycloalkano pyridines |
DE19627430A1 (de) | 1996-07-08 | 1998-01-15 | Bayer Ag | Bicyclisch kondensierte Pyridine |
AR008789A1 (es) | 1996-07-31 | 2000-02-23 | Bayer Corp | Piridinas y bifenilos substituidos |
DE19704244A1 (de) | 1997-02-05 | 1998-08-06 | Bayer Ag | 5-Hydroxy-alkyl substituierte Phenyle |
DE19709125A1 (de) | 1997-03-06 | 1998-09-10 | Bayer Ag | Substituierte Chinoline |
DE19741051A1 (de) | 1997-09-18 | 1999-03-25 | Bayer Ag | Hetero-Tetrahydrochinoline |
MA24643A1 (fr) * | 1997-09-18 | 1999-04-01 | Bayer Ag | Tetrahydro-naphtalenes substitues et composes analogues |
DE19741399A1 (de) | 1997-09-19 | 1999-03-25 | Bayer Ag | Tetrahydrochinoline |
DE19935966A1 (de) | 1999-07-30 | 2001-02-01 | Bayer Ag | Verfahren zur Reduktion von Ketoalkoholen |
DE10148436A1 (de) | 2001-10-01 | 2003-04-17 | Bayer Ag | Tetrahydrochinoline |
DE10250687A1 (de) | 2002-10-31 | 2004-05-13 | Bayer Ag | 7H-Dibenzo(b,g)(1,5)dioxocin-5-on-Derivate und ihre Verwendung |
EP1828137B1 (de) | 2004-12-18 | 2012-04-25 | Bayer Pharma Aktiengesellschaft | 4-cycloalkyl-substituierte tetrahydrochinolinderivate und deren verwendung als medikamente |
MX2007007187A (es) | 2004-12-18 | 2007-08-14 | Bayer Healthcare Ag | Derivados de (5s)-3-[(s)-fluoro-(4-trifluorometilfenil)metil]-5,6, 7,8-tetrahidroquinolin-5-ol y su uso como inhibidores de la proteina de transferencia de ester de colesterol. |
-
2006
- 2006-03-18 DE DE102006012548A patent/DE102006012548A1/de not_active Withdrawn
-
2007
- 2007-03-06 DO DO2007000043A patent/DOP2007000043A/es unknown
- 2007-03-07 MX MX2008011893A patent/MX2008011893A/es unknown
- 2007-03-07 AU AU2007229092A patent/AU2007229092A1/en not_active Abandoned
- 2007-03-07 US US12/225,211 patent/US8227511B2/en active Active
- 2007-03-07 WO PCT/EP2007/001930 patent/WO2007107243A1/de active Application Filing
- 2007-03-07 KR KR1020087025401A patent/KR101440633B1/ko active IP Right Grant
- 2007-03-07 EP EP07711808A patent/EP1999123A1/de not_active Withdrawn
- 2007-03-07 BR BRPI0708851-5A patent/BRPI0708851A2/pt not_active IP Right Cessation
- 2007-03-07 RU RU2008141240/04A patent/RU2459817C2/ru not_active IP Right Cessation
- 2007-03-07 CN CN2007800173102A patent/CN101443321B/zh active Active
- 2007-03-07 CA CA002645884A patent/CA2645884A1/en not_active Abandoned
- 2007-03-07 JP JP2009500728A patent/JP5285594B2/ja active Active
- 2007-03-13 AR ARP070101018A patent/AR059831A1/es unknown
- 2007-03-16 TW TW096109018A patent/TW200812998A/zh unknown
- 2007-03-16 UY UY30215A patent/UY30215A1/es not_active Application Discontinuation
- 2007-03-16 PE PE2007000289A patent/PE20080005A1/es not_active Application Discontinuation
-
2008
- 2008-09-11 ZA ZA200807809A patent/ZA200807809B/xx unknown
- 2008-09-18 EC EC2008008745A patent/ECSP088745A/es unknown
- 2008-09-19 CR CR10305A patent/CR10305A/es not_active Application Discontinuation
-
2009
- 2009-11-13 HK HK09110652.9A patent/HK1132731A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
DOP2007000043A (es) | 2007-09-30 |
TW200812998A (en) | 2008-03-16 |
WO2007107243A1 (de) | 2007-09-27 |
HK1132731A1 (en) | 2010-03-05 |
US20090306197A1 (en) | 2009-12-10 |
US8227511B2 (en) | 2012-07-24 |
PE20080005A1 (es) | 2008-03-14 |
CN101443321A (zh) | 2009-05-27 |
AU2007229092A1 (en) | 2007-09-27 |
BRPI0708851A2 (pt) | 2011-06-14 |
RU2008141240A (ru) | 2010-04-27 |
JP5285594B2 (ja) | 2013-09-11 |
CN101443321B (zh) | 2012-09-26 |
DE102006012548A1 (de) | 2007-09-20 |
AR059831A1 (es) | 2008-04-30 |
KR20090004997A (ko) | 2009-01-12 |
CR10305A (es) | 2009-02-19 |
CA2645884A1 (en) | 2007-09-27 |
ZA200807809B (en) | 2009-11-25 |
UY30215A1 (es) | 2007-10-31 |
RU2459817C2 (ru) | 2012-08-27 |
MX2008011893A (es) | 2008-09-30 |
KR101440633B1 (ko) | 2014-09-22 |
EP1999123A1 (de) | 2008-12-10 |
JP2009530322A (ja) | 2009-08-27 |
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