RU2011120822A - Способ получения замещенных фенилаланинов - Google Patents

Способ получения замещенных фенилаланинов Download PDF

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Publication number
RU2011120822A
RU2011120822A RU2011120822/04A RU2011120822A RU2011120822A RU 2011120822 A RU2011120822 A RU 2011120822A RU 2011120822/04 A RU2011120822/04 A RU 2011120822/04A RU 2011120822 A RU2011120822 A RU 2011120822A RU 2011120822 A RU2011120822 A RU 2011120822A
Authority
RU
Russia
Prior art keywords
compound
formula
arylalkyl
salt
heterocycle
Prior art date
Application number
RU2011120822/04A
Other languages
English (en)
Russian (ru)
Inventor
Хью Альфред Бергун
Раманаиах К. Канамарлапуди
Айан Фрейзер ПИКЕРСДЖИЛЛ
Чжи-Цай Ши
Вэньсюэ У
Хаймин Чжан
Мэттью Манчжу Чжао
Original Assignee
Лексикон Фармасьютикалз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Лексикон Фармасьютикалз, Инк. filed Critical Лексикон Фармасьютикалз, Инк.
Publication of RU2011120822A publication Critical patent/RU2011120822A/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
RU2011120822/04A 2008-10-24 2008-10-24 Способ получения замещенных фенилаланинов RU2011120822A (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2008/081054 WO2010047712A1 (en) 2008-10-24 2008-10-24 Process for the preparation of substituted phenylalanines

Publications (1)

Publication Number Publication Date
RU2011120822A true RU2011120822A (ru) 2012-11-27

Family

ID=40785295

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2011120822/04A RU2011120822A (ru) 2008-10-24 2008-10-24 Способ получения замещенных фенилаланинов

Country Status (11)

Country Link
EP (1) EP2358685A1 (ja)
JP (1) JP2012506427A (ja)
KR (1) KR20110074875A (ja)
CN (1) CN102203069A (ja)
AU (1) AU2008363274A1 (ja)
BR (1) BRPI0823136A2 (ja)
CA (1) CA2741563A1 (ja)
IL (1) IL211996A0 (ja)
MX (1) MX2011004168A (ja)
RU (1) RU2011120822A (ja)
WO (1) WO2010047712A1 (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015089137A1 (en) * 2013-12-11 2015-06-18 Karos Pharmaceuticals, Inc. Acylguanidines as tryptophan hydroxylase inhibitors
IL277071B1 (en) 2018-03-08 2024-03-01 Incyte Corp Aminopyrizine diol compounds as PI3K–y inhibitors
US11046658B2 (en) 2018-07-02 2021-06-29 Incyte Corporation Aminopyrazine derivatives as PI3K-γ inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0620756B1 (pt) * 2005-12-29 2021-06-01 Tersera Therapeutics Llc Derivados de aminoácido multicíclicos, formulação farmacêutica compreendendo os mesmos e seus usos para inibir a atividade de triptofano hidroxilase 1 (tph1)
UA99270C2 (en) * 2006-12-12 2012-08-10 Лексикон Фармасьютикалз, Инк. 4-phenyl-6-(2,2,2-trifluoro-1-phenylethoxy)pyrimidine-based compounds and methods of their use

Also Published As

Publication number Publication date
IL211996A0 (en) 2011-06-30
AU2008363274A1 (en) 2010-04-29
CA2741563A1 (en) 2010-04-29
CN102203069A (zh) 2011-09-28
EP2358685A1 (en) 2011-08-24
BRPI0823136A2 (pt) 2015-06-16
JP2012506427A (ja) 2012-03-15
MX2011004168A (es) 2011-05-23
WO2010047712A1 (en) 2010-04-29
KR20110074875A (ko) 2011-07-04

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