KR20110074875A - 치환된 페닐알라닌의 제조 방법 - Google Patents

치환된 페닐알라닌의 제조 방법 Download PDF

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Publication number
KR20110074875A
KR20110074875A KR1020117009174A KR20117009174A KR20110074875A KR 20110074875 A KR20110074875 A KR 20110074875A KR 1020117009174 A KR1020117009174 A KR 1020117009174A KR 20117009174 A KR20117009174 A KR 20117009174A KR 20110074875 A KR20110074875 A KR 20110074875A
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KR
South Korea
Prior art keywords
formula
compound
alkyl
aryl
optionally substituted
Prior art date
Application number
KR1020117009174A
Other languages
English (en)
Korean (ko)
Inventor
휴 알프레드 부르군
라마나이아 씨. 카나마를라푸디
이아인 프레이저 피커스길
지-카이 쉬
웬슈에 우
하이밍 장
매튜 망주 자오
Original Assignee
렉시컨 파마슈티컬스 인코퍼레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 렉시컨 파마슈티컬스 인코퍼레이티드 filed Critical 렉시컨 파마슈티컬스 인코퍼레이티드
Publication of KR20110074875A publication Critical patent/KR20110074875A/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1020117009174A 2008-10-24 2008-10-24 치환된 페닐알라닌의 제조 방법 KR20110074875A (ko)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2008/081054 WO2010047712A1 (en) 2008-10-24 2008-10-24 Process for the preparation of substituted phenylalanines

Publications (1)

Publication Number Publication Date
KR20110074875A true KR20110074875A (ko) 2011-07-04

Family

ID=40785295

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020117009174A KR20110074875A (ko) 2008-10-24 2008-10-24 치환된 페닐알라닌의 제조 방법

Country Status (11)

Country Link
EP (1) EP2358685A1 (ja)
JP (1) JP2012506427A (ja)
KR (1) KR20110074875A (ja)
CN (1) CN102203069A (ja)
AU (1) AU2008363274A1 (ja)
BR (1) BRPI0823136A2 (ja)
CA (1) CA2741563A1 (ja)
IL (1) IL211996A0 (ja)
MX (1) MX2011004168A (ja)
RU (1) RU2011120822A (ja)
WO (1) WO2010047712A1 (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015089137A1 (en) * 2013-12-11 2015-06-18 Karos Pharmaceuticals, Inc. Acylguanidines as tryptophan hydroxylase inhibitors
PL3762368T3 (pl) 2018-03-08 2022-06-06 Incyte Corporation ZWIĄZKI AMINOPIRAZYNODIOLOWE JAKO INHIBITORY PI3K-γ
WO2020010003A1 (en) 2018-07-02 2020-01-09 Incyte Corporation AMINOPYRAZINE DERIVATIVES AS PI3K-γ INHIBITORS

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA96936C2 (uk) * 2005-12-29 2011-12-26 Лексикон Фармасьютикалз, Инк. Поліциклічні похідні амінокислот і їх застосування
UA99270C2 (en) * 2006-12-12 2012-08-10 Лексикон Фармасьютикалз, Инк. 4-phenyl-6-(2,2,2-trifluoro-1-phenylethoxy)pyrimidine-based compounds and methods of their use

Also Published As

Publication number Publication date
CA2741563A1 (en) 2010-04-29
AU2008363274A1 (en) 2010-04-29
BRPI0823136A2 (pt) 2015-06-16
EP2358685A1 (en) 2011-08-24
MX2011004168A (es) 2011-05-23
JP2012506427A (ja) 2012-03-15
CN102203069A (zh) 2011-09-28
IL211996A0 (en) 2011-06-30
RU2011120822A (ru) 2012-11-27
WO2010047712A1 (en) 2010-04-29

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