RU2009119567A - Уменьшение избыточной массы тела или ожирения - Google Patents

Уменьшение избыточной массы тела или ожирения Download PDF

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Publication number
RU2009119567A
RU2009119567A RU2009119567/15A RU2009119567A RU2009119567A RU 2009119567 A RU2009119567 A RU 2009119567A RU 2009119567/15 A RU2009119567/15 A RU 2009119567/15A RU 2009119567 A RU2009119567 A RU 2009119567A RU 2009119567 A RU2009119567 A RU 2009119567A
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RU
Russia
Prior art keywords
obesity
reducing
overbody
pharmaceutical composition
use according
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RU2009119567/15A
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English (en)
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RU2443417C2 (ru
Inventor
НАДЬ Петер ЛИТЕРАТИ (HU)
Надь Петер Литерати
Зольтан СИЛЬВАШШИ (HU)
Зольтан СИЛЬВАШШИ
Кальман ТОРИ (HU)
Кальман Тори
Ласло ВИГ (HU)
Ласло Виг
Кальман ТАКАЧ (HU)
Кальман Такач
Йожеф МАНДЛЬ (HU)
Йожеф МАНДЛЬ
Балаж ШИМЕГИ (HU)
Балаж ШИМЕГИ
Шандор БЕРНАТ (HU)
Шандор Бернат
Аттила КОЛОНИЧ (HU)
Аттила Колонич
Габор БАЛОГ (HU)
Габор Балог
Янош ЭГРИ (HU)
Янош Эгри
Original Assignee
Н-Джин Ресерч Лабораториз Инк. (US)
Н-Джин Ресерч Лабораториз Инк.
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Application filed by Н-Джин Ресерч Лабораториз Инк. (US), Н-Джин Ресерч Лабораториз Инк. filed Critical Н-Джин Ресерч Лабораториз Инк. (US)
Publication of RU2009119567A publication Critical patent/RU2009119567A/ru
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Publication of RU2443417C2 publication Critical patent/RU2443417C2/ru

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Fats And Perfumes (AREA)
  • Pyridine Compounds (AREA)

Abstract

1. Применение O-(3-пиперидино-2-гидрокси-1-пропил)-никотинамидоксима или его фармацевтически приемлемой соли присоединения кислоты для получения фармацевтической композиции, пригодной для предотвращения аномального прироста массы тела или уменьшения избыточной массы тела или ожирения. ! 2. Применение по п.1, где применяют O-(3-пиперидино-2-гидрокси-1-пропил)-никотинамидоксимадигидрохлорид. ! 3. Применение по п.1 или 2, где фармацевтическую композицию применяют для уменьшения индекса массы тела, равного 25-30 кг/м2. ! 4. Применение по п.1 или 2, где фармацевтическую композицию применяют для уменьшения индекса массы тела, равного более 30 кг/м2.

Claims (4)

1. Применение O-(3-пиперидино-2-гидрокси-1-пропил)-никотинамидоксима или его фармацевтически приемлемой соли присоединения кислоты для получения фармацевтической композиции, пригодной для предотвращения аномального прироста массы тела или уменьшения избыточной массы тела или ожирения.
2. Применение по п.1, где применяют O-(3-пиперидино-2-гидрокси-1-пропил)-никотинамидоксимадигидрохлорид.
3. Применение по п.1 или 2, где фармацевтическую композицию применяют для уменьшения индекса массы тела, равного 25-30 кг/м2.
4. Применение по п.1 или 2, где фармацевтическую композицию применяют для уменьшения индекса массы тела, равного более 30 кг/м2.
RU2009119567/15A 2006-11-02 2007-07-23 Уменьшение избыточной массы тела или ожирения RU2443417C2 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US85611706P 2006-11-02 2006-11-02
US60/856,117 2006-11-02
US11/687,945 US7763601B2 (en) 2006-11-02 2007-03-19 Prevention and treatment of obesity
US11/687,945 2007-03-19

Publications (2)

Publication Number Publication Date
RU2009119567A true RU2009119567A (ru) 2010-12-10
RU2443417C2 RU2443417C2 (ru) 2012-02-27

Family

ID=38592002

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2009119567/15A RU2443417C2 (ru) 2006-11-02 2007-07-23 Уменьшение избыточной массы тела или ожирения

Country Status (20)

Country Link
US (1) US7763601B2 (ru)
EP (1) EP2089031B1 (ru)
JP (1) JP2010509199A (ru)
KR (1) KR20090082442A (ru)
AT (1) ATE489090T1 (ru)
AU (1) AU2007315931A1 (ru)
BR (1) BRPI0717867A2 (ru)
CA (1) CA2668382A1 (ru)
DE (1) DE602007010819D1 (ru)
DK (1) DK2089031T3 (ru)
HK (1) HK1131737A1 (ru)
HR (1) HRP20110023T1 (ru)
IL (1) IL198296A (ru)
MX (1) MX2009004538A (ru)
NO (1) NO20092025L (ru)
PL (1) PL2089031T3 (ru)
PT (1) PT2089031E (ru)
RU (1) RU2443417C2 (ru)
SI (1) SI2089031T1 (ru)
WO (1) WO2008053256A1 (ru)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11241420B2 (en) 2007-04-11 2022-02-08 Omeros Corporation Compositions and methods for prophylaxis and treatment of addictions
EP3788877A1 (en) * 2007-04-11 2021-03-10 Omeros Corporation Compositions and methods for prophylaxis and treatment of addictions
US20160331729A9 (en) 2007-04-11 2016-11-17 Omeros Corporation Compositions and methods for prophylaxis and treatment of addictions
WO2009074835A1 (en) * 2007-12-10 2009-06-18 N-Gene Research Laboratories Inc. Dose reduction of a cannabinoid cb1 receptor antagonist in the treatment of overweight or obesity
HUP1100444A2 (en) 2011-08-17 2013-02-28 Pharma Gene Sa Pharmaceutical composition
HUP1100445A2 (en) 2011-08-17 2013-02-28 Pharma Gene Sa Pharmaceutical composition
HUP1800298A1 (hu) 2018-08-30 2020-05-28 N Gene Res Laboratories Inc Gyógyszerkombináció béta-receptor blokkolók hatásának módosítására és a mellékhatások csökkentésére

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4187220A (en) 1977-08-30 1980-02-05 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T. New O-(3-amino-2-hydroxy-propyl)-amidoxime derivatives, process for the preparation thereof and pharmaceutical compositions containing same
US4287220A (en) * 1980-02-19 1981-09-01 Frito-Lay, Inc. Hull containing compositions
HU207988B (en) * 1988-10-20 1993-07-28 Biorex Kutato Fejlesztoe Kft Process for producing halogenides of o-/3-amino-2-hydroxy-propyl/hydroximic acid and pharmaceutical compositions containing them as active components
HU9502843D0 (en) 1995-09-29 1995-11-28 Livigene Ltd Pharmaceutical composition
US6884424B2 (en) 1995-12-22 2005-04-26 N-Gene Research Laboratories Inc. Method for treating the pathological lesions of the skin that develop by ultraviolet radiation of the sunlight
US6458371B1 (en) 1995-12-22 2002-10-01 Medgene, Limited Cosmetic composition and a method for the prevention and/or reduction of the photoaging processes of the skin
HU9701081D0 (en) 1997-06-23 1997-08-28 Gene Research Lab Inc N Pharmaceutical composition of antitumoral activity
HUP9701080A3 (en) 1997-06-23 1999-05-28 Gene Res Lab Inc New York N Pharmaceutical composition containing a compound of antiviral activity and a hydroximic acid ester derivative
AU5296799A (en) 1998-08-03 2000-02-28 N-Gene Kutato Kft. Pharmaceutical compositions against autoimmune diseases
UA65635C2 (ru) * 1998-09-03 2004-04-15 Н-Гене Кутато Кфт. НЕНАСЫЧЕННЫЕ ПРОИЗВОДНЫЕ ГИДРОКСИМОВОЙ КИСЛОТЫ, ИМЕЮЩИЕ СВОЙСТВА ИНГИБИТОРОВ NAD<sup>+-ADP-РИБОЗИЛТРАНСФЕРАЗЫ
CA2452558C (en) 2001-07-17 2009-12-22 N-Gene Research Laboratories Inc. A synergistic pharmaceutical combination for the prevention or treatment of diabetes
HUP0401177A2 (en) 2004-06-14 2007-09-28 N Gene Res Lab Inc Pharmaceutical composition for increasing the mitochondrial genesis
HUP0401176A2 (en) 2004-06-14 2007-09-28 N Gene Res Lab Inc Pharmaceutical composition having prpkinetic effect
HUP0500145A2 (en) 2005-01-28 2006-11-28 Gene Res Lab N Use of o-(3-piperidino-2-hydroxy-1-propyl)-nicotinic amidoxime for preparation of medicaments against oral diseases
CN101534836B (zh) 2006-09-05 2011-09-28 彼帕科学公司 Parp抑制剂在制备治疗肥胖症的药物中的用途

Also Published As

Publication number Publication date
SI2089031T1 (sl) 2011-04-29
EP2089031A1 (en) 2009-08-19
IL198296A (en) 2011-09-27
BRPI0717867A2 (pt) 2013-10-29
WO2008053256A1 (en) 2008-05-08
PT2089031E (pt) 2011-02-24
NO20092025L (no) 2009-06-02
EP2089031B1 (en) 2010-11-24
DK2089031T3 (da) 2011-02-14
KR20090082442A (ko) 2009-07-30
ATE489090T1 (de) 2010-12-15
DE602007010819D1 (de) 2011-01-05
MX2009004538A (es) 2009-05-22
IL198296A0 (en) 2010-02-17
US7763601B2 (en) 2010-07-27
RU2443417C2 (ru) 2012-02-27
PL2089031T3 (pl) 2011-05-31
AU2007315931A1 (en) 2008-05-08
HK1131737A1 (en) 2010-02-05
CA2668382A1 (en) 2008-05-08
JP2010509199A (ja) 2010-03-25
US20080108673A1 (en) 2008-05-08
HRP20110023T1 (hr) 2011-04-30

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20150724