RU2007137396A - Эндопаразитицидное средство - Google Patents

Эндопаразитицидное средство Download PDF

Info

Publication number
RU2007137396A
RU2007137396A RU2007137396/15A RU2007137396A RU2007137396A RU 2007137396 A RU2007137396 A RU 2007137396A RU 2007137396/15 A RU2007137396/15 A RU 2007137396/15A RU 2007137396 A RU2007137396 A RU 2007137396A RU 2007137396 A RU2007137396 A RU 2007137396A
Authority
RU
Russia
Prior art keywords
agent according
endoparasiticidal
solvent
endoparasiticidal agent
emodepside
Prior art date
Application number
RU2007137396/15A
Other languages
English (en)
Other versions
RU2417101C2 (ru
Inventor
Венката-Рангарао КАНИКАНТИ (DE)
Венката-Рангарао КАНИКАНТИ
Михаэль ТРОЙБЕЛЬ (DE)
Михаэль Тройбель
Original Assignee
Байер ХельсКер АГ (DE)
Байер ХельсКер АГ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36216785&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RU2007137396(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Байер ХельсКер АГ (DE), Байер ХельсКер АГ filed Critical Байер ХельсКер АГ (DE)
Publication of RU2007137396A publication Critical patent/RU2007137396A/ru
Application granted granted Critical
Publication of RU2417101C2 publication Critical patent/RU2417101C2/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/84Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms six-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/55131,4-Benzodiazepines, e.g. diazepam or clozapine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/15Depsipeptides; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • A61K9/0017Non-human animal skin, e.g. pour-on, spot-on
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/10Anthelmintics
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N2300/00Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Wood Science & Technology (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Plant Pathology (AREA)
  • Dermatology (AREA)
  • Pest Control & Pesticides (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Organic Chemistry (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

1. Эндопаразитицидное средство, содержащее в качестве действующих веществ эмодепсид, а также празиквантел или эпсипрантел, и в качестве растворителя 1,2-изопропилиденглицерин, причем содержание воды в средстве составляет не более 1 вес.%. ! 2. Эндопаразитицидное средство по п.1, отличающееся тем, что в качестве действующих веществ оно содержит эмодепсид и празиквантел. ! 3. Эндопаразитицидное средство по п.1, отличающееся тем, что используемый растворитель содержит, по меньшей мере, 60 об.% 1,2-изопропилиденглицерина. ! 4. Эндопаразитицидное средство по пп.1-3, отличающееся тем, что оно содержит 1,2-изопропилиденглицерин в качестве единственного растворителя. ! 5. Метод получения эндопаразитицидного средства по пп.1-4, отличающийся тем, что действующие вещества смешивают с растворителями и при необходимости с дополнительными добавками. ! 6. Использование эмодепсида и празиквантела или эпсипрантела для получения эндопаразитицидного средства, которое содержит 1,2-изопропилиденглицерин в качестве растворителя, обнаруживает содержание воды не более 1 вес.% и годится для наружного применения для борьбы с эндопаразитами.

Claims (6)

1. Эндопаразитицидное средство, содержащее в качестве действующих веществ эмодепсид, а также празиквантел или эпсипрантел, и в качестве растворителя 1,2-изопропилиденглицерин, причем содержание воды в средстве составляет не более 1 вес.%.
2. Эндопаразитицидное средство по п.1, отличающееся тем, что в качестве действующих веществ оно содержит эмодепсид и празиквантел.
3. Эндопаразитицидное средство по п.1, отличающееся тем, что используемый растворитель содержит, по меньшей мере, 60 об.% 1,2-изопропилиденглицерина.
4. Эндопаразитицидное средство по пп.1-3, отличающееся тем, что оно содержит 1,2-изопропилиденглицерин в качестве единственного растворителя.
5. Метод получения эндопаразитицидного средства по пп.1-4, отличающийся тем, что действующие вещества смешивают с растворителями и при необходимости с дополнительными добавками.
6. Использование эмодепсида и празиквантела или эпсипрантела для получения эндопаразитицидного средства, которое содержит 1,2-изопропилиденглицерин в качестве растворителя, обнаруживает содержание воды не более 1 вес.% и годится для наружного применения для борьбы с эндопаразитами.
RU2007137396/15A 2005-03-11 2006-02-27 Эндопаразитицидное средство RU2417101C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005011779.1 2005-03-11
DE102005011779A DE102005011779A1 (de) 2005-03-11 2005-03-11 Endoparasitizide Mittel

Publications (2)

Publication Number Publication Date
RU2007137396A true RU2007137396A (ru) 2009-04-20
RU2417101C2 RU2417101C2 (ru) 2011-04-27

Family

ID=36216785

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2007137396/15A RU2417101C2 (ru) 2005-03-11 2006-02-27 Эндопаразитицидное средство

Country Status (31)

Country Link
US (1) US20080255037A1 (ru)
EP (1) EP1863535B1 (ru)
JP (2) JP5232635B2 (ru)
KR (3) KR20070119673A (ru)
CN (2) CN102908609A (ru)
AR (2) AR053691A1 (ru)
AU (1) AU2006222314B2 (ru)
BR (1) BRPI0608287B1 (ru)
CA (1) CA2600638C (ru)
CR (1) CR9364A (ru)
DE (1) DE102005011779A1 (ru)
DK (1) DK1863535T3 (ru)
ES (1) ES2639394T3 (ru)
GT (1) GT200600106A (ru)
HR (1) HRP20171354T1 (ru)
HU (1) HUE036294T2 (ru)
IL (1) IL185856A (ru)
MX (1) MX2007010990A (ru)
MY (1) MY163037A (ru)
NO (1) NO342645B1 (ru)
NZ (1) NZ561754A (ru)
PE (1) PE20061071A1 (ru)
PL (1) PL1863535T3 (ru)
PT (1) PT1863535T (ru)
RU (1) RU2417101C2 (ru)
SI (1) SI1863535T1 (ru)
TW (1) TW200700085A (ru)
UA (1) UA94705C2 (ru)
UY (1) UY29417A1 (ru)
WO (1) WO2006094664A1 (ru)
ZA (1) ZA200707732B (ru)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102004055316A1 (de) * 2004-11-16 2006-05-18 Bayer Healthcare Ag Verhinderung vertikaler Endoparasiten-Infektionen
DE102005011779A1 (de) * 2005-03-11 2006-09-14 Bayer Healthcare Ag Endoparasitizide Mittel
DE102009012423A1 (de) * 2009-03-10 2010-09-16 Bayer Animal Health Gmbh Zubereitung auf Ölbasis
UA108641C2 (uk) 2010-04-02 2015-05-25 Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування
UA115232C2 (uk) * 2011-12-21 2017-10-10 Байєр Інтеллектуал Проперті Гмбх Препарат, що містить аморфний емодепсид
US12122759B2 (en) 2017-11-07 2024-10-22 Elanco Animal Health Gmbh Method for the synthesis of cyclic depsipeptides
EP3480195A1 (en) 2017-11-07 2019-05-08 Bayer Animal Health GmbH Method for the synthesis of cyclic depsipeptides
CA3147171A1 (en) * 2019-08-14 2021-02-18 Vetoquinol Sa Compositions comprising tigolaner for controlling parasites
CN111346046B (zh) * 2020-03-06 2021-07-09 安徽农业大学 一种含莫西菌素注射用缓释凝胶制剂及制备方法

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2362539C2 (de) * 1973-12-17 1986-05-07 Merck Patent Gmbh, 6100 Darmstadt 2-Acyl-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isochinoline, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
CA1194791A (en) * 1981-05-08 1985-10-08 John M. Ballany Parasiticidal pour-on compositions
DE3472678D1 (de) * 1983-07-18 1988-08-18 Beecham Group Plc Benzazepine and benzoxazepine derivatives
DE3634755A1 (de) * 1986-10-11 1988-04-14 Bayer Ag Dermale behandlung von wurmerkrankungen der katze mit praziquantel
NO176766C (no) * 1989-02-07 1995-05-24 Meiji Seika Kaisha Fremgangsmåte for fremstilling av en forbindelse med anthelmintaktivitet
WO1993019053A1 (fr) * 1992-03-17 1993-09-30 Fujisawa Pharmaceutical Co., Ltd. Derive de depsipeptide, production et utilisation
DE4317458A1 (de) * 1992-06-11 1993-12-16 Bayer Ag Verwendung von cyclischen Depsipeptiden mit 18 Ringatomen zur Bekämpfung von Endoparasiten, neue cyclische Depsipeptide mit 18 Ringatomen und Verfahren zu ihrer Herstellung
DE4317457A1 (de) * 1993-05-26 1994-12-01 Bayer Ag Octacyclodepsipeptide mit endoparasitizider Wirkung
DE4317432A1 (de) * 1993-05-26 1994-12-01 Bayer Ag Octacyclodepsipeptide mit endoparasitizider Wirkung
DE4400464A1 (de) * 1994-01-11 1995-07-13 Bayer Ag Endoparasitizide Mittel
NZ260018A (en) * 1994-03-03 1995-10-26 Bomac Lab Ltd Benzimidazole compositions and anthelmintic compositions
DE19520275A1 (de) * 1995-06-02 1996-12-05 Bayer Ag Endoparasitizide Mittel
DE19601263A1 (de) * 1996-01-16 1997-07-17 Bayer Ag Anthelmintische Paste
DE19628776A1 (de) * 1996-07-17 1998-01-22 Bayer Ag Oral applizierbare Granulate von Hexahydropyrazinderivaten
US6340672B1 (en) * 2000-02-16 2002-01-22 Phoenix Scientific, Inc. Parasiticidal formulation and a method of making this formulation
DE10008128A1 (de) * 2000-02-22 2001-08-23 Bayer Ag Endoparasitizide Mittel
DE60118132T2 (de) * 2000-10-10 2006-10-19 Wyeth Anthelmintika
US6893652B2 (en) * 2001-08-27 2005-05-17 Wyeth Endoparasiticidal gel composition
US7001889B2 (en) * 2002-06-21 2006-02-21 Merial Limited Anthelmintic oral homogeneous veterinary pastes
HUE032009T2 (en) * 2003-04-04 2017-09-28 Merial Inc Veterinary preparations for topical veterinary use
DE10358525A1 (de) * 2003-12-13 2005-07-07 Bayer Healthcare Ag Endoparasitizide Mittel zur topischen Applikation
DE102004001558A1 (de) * 2004-01-10 2005-08-18 Bayer Healthcare Ag Arzneimittel zur topischen Applikation bei Tieren
DE102005011779A1 (de) * 2005-03-11 2006-09-14 Bayer Healthcare Ag Endoparasitizide Mittel

Also Published As

Publication number Publication date
WO2006094664A1 (de) 2006-09-14
KR101856817B1 (ko) 2018-05-10
IL185856A0 (en) 2008-01-06
NZ561754A (en) 2010-11-26
UA94705C2 (ru) 2011-06-10
HRP20171354T1 (hr) 2017-11-03
KR20160148717A (ko) 2016-12-26
JP5232635B2 (ja) 2013-07-10
HUE036294T2 (hu) 2018-06-28
ES2639394T3 (es) 2017-10-26
BRPI0608287A2 (pt) 2009-12-22
ZA200707732B (en) 2009-06-24
TW200700085A (en) 2007-01-01
BRPI0608287B1 (pt) 2020-03-24
IL185856A (en) 2016-06-30
NO342645B1 (no) 2018-06-25
DK1863535T3 (en) 2017-09-25
AR110174A2 (es) 2019-03-06
AU2006222314A1 (en) 2006-09-14
KR20140043946A (ko) 2014-04-11
AU2006222314B2 (en) 2012-04-05
AR053691A1 (es) 2007-05-16
KR20070119673A (ko) 2007-12-20
EP1863535A1 (de) 2007-12-12
CA2600638C (en) 2015-10-27
MY163037A (en) 2017-08-15
JP2013079268A (ja) 2013-05-02
RU2417101C2 (ru) 2011-04-27
GT200600106A (es) 2006-11-07
PT1863535T (pt) 2017-09-13
NO20075039L (no) 2007-10-05
US20080255037A1 (en) 2008-10-16
CN101193657A (zh) 2008-06-04
CR9364A (es) 2008-02-12
EP1863535B1 (de) 2017-06-07
JP2008532959A (ja) 2008-08-21
SI1863535T1 (sl) 2017-10-30
CN102908609A (zh) 2013-02-06
UY29417A1 (es) 2006-10-31
PL1863535T3 (pl) 2017-10-31
CA2600638A1 (en) 2006-09-14
MX2007010990A (es) 2007-11-07
PE20061071A1 (es) 2006-11-30
DE102005011779A1 (de) 2006-09-14

Similar Documents

Publication Publication Date Title
RU2007137396A (ru) Эндопаразитицидное средство
EA200800731A1 (ru) Жидкие составы гербицидов на основе сульфонилмочевины
EA200400816A1 (ru) Замещенные аналоги хиназолин-4-иламина в качестве модуляторов капсаицина
TR200100149T2 (tr) Dual anjiyotensin endotelin alıcı antagonistleri olarak bifenil-sülfonamitler
EA200101232A1 (ru) Соединения феноксипропиламина
UY31406A1 (es) "producto de dispersion solida que contiene un compuesto a base de n-aril urea".
EA200800751A1 (ru) Новые сульфонамидсодержащие твердые препараты
ATE426619T1 (de) Líslichkeit von cellulose in ionischen flussigkeiten unter zugabe von aminbase
CR8673A (es) Compuestos de difenil-ox-indol-2-ona y su uso en el tratamiento del cancer
EA200700817A1 (ru) Композиции амитраза
PE20061327A1 (es) Combinaciones de derivados de benzofurano y un antidepresivo para el tratamiento o la prevencion de la depresion
BRPI0718466B8 (pt) Bateria secundária de propriedades de alta taxa de descarga aperfeiçoadas
EA201001439A1 (ru) Трехфазная эмульсия (варианты), способ ее приготовления и нанесения
EA200401553A1 (ru) Гербицидная композиция
BRPI0509401A (pt) composições e métodos para branqueamento, mineralização e/ou fluoração de tecidos calcificados
EA200500528A1 (ru) Пиперазинил- и диазапанилбензамиды и бензтиоамиды
BR0317186A (pt) Concentrado de anticongelamento e composição refrigerante aquosa pronta para o uso para sistemas de refriamento em acionadores de célula de combustìvel, e, usos de compostos e de um concentrado de anticongelamento
RU2005116970A (ru) Бактерицидные средства
CL2003002293A1 (es) Compuestos derivados de indazol; su composicion farmaceutica; su uso en el tratamiento de hipertension ocular.
ATE235422T1 (de) Gelierungsstabiele polyhalogenphosphazenverbindungen
BRPI0409330A (pt) eliminador de oxigênio ativo derivado de substáncia natural e seu uso
EA200600559A1 (ru) Смеси поверхностно-активное вещество/растворитель
CO5630020A1 (es) Metodo mejorado para secar neotame y producto solido con contenido de neotam
EA201000432A1 (ru) Фунгицидные смеси тритиконазола и дифеноконазола
CL2007001747A1 (es) Compuestos derivados de aril y heteroaril-etil-acilguanidina; procedimiento de preparacion; composicion farmaceutica; y uso para el tratamiento y prevencion de la hipertension, insuficiencia cardiaca y afecciones renales entre otras.

Legal Events

Date Code Title Description
PC41 Official registration of the transfer of exclusive right

Effective date: 20130207