RU2006140964A - Применение флибансерина для лечения предменструальных и иных сексуальных расстройств у женщин - Google Patents

Применение флибансерина для лечения предменструальных и иных сексуальных расстройств у женщин Download PDF

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RU2006140964A
RU2006140964A RU2006140964/14A RU2006140964A RU2006140964A RU 2006140964 A RU2006140964 A RU 2006140964A RU 2006140964/14 A RU2006140964/14 A RU 2006140964/14A RU 2006140964 A RU2006140964 A RU 2006140964A RU 2006140964 A RU2006140964 A RU 2006140964A
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acid
flibanserin
sexual
women
optionally
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RU2006140964/14A
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RU2384333C2 (ru
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Роберт ПАЙК (US)
Роберт Пайк
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Берингер Ингельхайм Фармасьютиклз, Инк. (Us)
Берингер Ингельхайм Фармасьютиклз, Инк.
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Gynecology & Obstetrics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pregnancy & Childbirth (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Claims (10)

1. Способ лечения предменструальных расстройств, заключающийся во введении в организм в терапевтически эффективном количестве флибансерина, необязательно в виде его фармакологически приемлемых кислотно-аддитивных солей.
2. Способ по п.1 лечения предменструальных расстройств, выбранных из группы, включающей предменструальную дисфорию, предменструальный синдром и предменструальное расстройство настроения.
3. Способ лечения отвращения к половым сношениям и отсутствия полового влечения у женщин, заключающийся во введении в организм в терапевтически эффективном количестве флибансерина, необязательно в виде его фармакологически приемлемых кислотно-аддитивных солей.
4. Способ лечения недостаточности генитальной реакции у женщин, заключающийся во введении в организм в терапевтически эффективном количестве флибансерина, необязательно в виде его фармакологически приемлемых кислотно-аддитивных солей.
5. Способ лечения оргазмической дисфункции у женщин, заключающийся во введении в организм в терапевтически эффективном количестве флибансерина, необязательно в виде его фармакологически приемлемых кислотно-аддитивных солей.
6. Способ лечения сексуальных болевых расстройств у женщин, заключающийся во введении в организм в терапевтически эффективном количестве флибансерина, необязательно в виде его фармакологически приемлемых кислотно-аддитивных солей.
7. Способ по п.6 лечения сексуальных болевых расстройств, выбранных из группы, включающей диспареунию, вагинизм, генитальную боль, возникающую при некоитальной сексуальной стимуляции, сексуальную дисфункцию вследствие общего состояния здоровья и вызванную употреблением психоактивных веществ сексуальную дисфункцию.
8. Способ по одному из пп.1-7, отличающийся тем, что флибансерин применяют в виде его фармацевтически приемлемой кислотно-аддитивной соли, выбранной среди солей кислот из группы, включающей янтарную кислоту, бромистоводородную кислоту, уксусную кислоту, фумаровую кислоту, малеиновую кислоту, метансульфоновую кислоту, молочную кислоту, фосфорную кислоту, хлористоводородную кислоту, серную кислоту, винную кислоту, лимонную кислоту и их смеси.
9. Способ по одному из пп.1-7, отличающийся тем, что флибансерин применяют в суточной дозе от 0,1 до 400 мг.
10. Способ по п.8, отличающийся тем, что флибансерин применяют в суточной дозе от 0,1 до 400 мг.
RU2006140964/14A 2004-04-22 2005-04-18 Применение флибансерина для лечения предменструальных и иных сексуальных расстройств у женщин RU2384333C2 (ru)

Applications Claiming Priority (2)

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US56466004P 2004-04-22 2004-04-22
US60/564,660 2004-04-22

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RU2006140964A true RU2006140964A (ru) 2008-05-27
RU2384333C2 RU2384333C2 (ru) 2010-03-20

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US (3) US20050239798A1 (ru)
EP (1) EP1740180B1 (ru)
JP (1) JP2007533687A (ru)
KR (1) KR20070014186A (ru)
CN (1) CN1946403A (ru)
AR (1) AR048833A1 (ru)
AT (1) ATE474578T1 (ru)
AU (1) AU2005235423A1 (ru)
BR (1) BRPI0510094A (ru)
CA (2) CA2563167C (ru)
DE (1) DE602005022427D1 (ru)
ES (1) ES2345894T3 (ru)
IL (1) IL178758A0 (ru)
MX (1) MXPA06012116A (ru)
NZ (1) NZ551418A (ru)
PE (1) PE20060257A1 (ru)
RU (1) RU2384333C2 (ru)
TW (1) TW200603807A (ru)
UY (1) UY28860A1 (ru)
WO (1) WO2005102343A1 (ru)
ZA (1) ZA200608024B (ru)

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AR048833A1 (es) 2006-05-31
CA2563167A1 (en) 2005-11-03
ZA200608024B (en) 2007-12-27
EP1740180A1 (en) 2007-01-10
ES2345894T3 (es) 2010-10-05
US20050239798A1 (en) 2005-10-27
TW200603807A (en) 2006-02-01
WO2005102343A1 (en) 2005-11-03
JP2007533687A (ja) 2007-11-22
US20150111898A1 (en) 2015-04-23
US20130079356A1 (en) 2013-03-28
NZ551418A (en) 2009-09-25
UY28860A1 (es) 2005-11-30
CA2563167C (en) 2013-04-02
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BRPI0510094A (pt) 2007-10-16
AU2005235423A1 (en) 2005-11-03
ATE474578T1 (de) 2010-08-15
RU2384333C2 (ru) 2010-03-20
PE20060257A1 (es) 2006-04-11
EP1740180B1 (en) 2010-07-21
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CA2802600A1 (en) 2005-11-03
MXPA06012116A (es) 2007-01-17

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