RU2006140958A - Иммунизация против менингококков серогруппы y с помощью белков - Google Patents

Иммунизация против менингококков серогруппы y с помощью белков Download PDF

Info

Publication number
RU2006140958A
RU2006140958A RU2006140958/13A RU2006140958A RU2006140958A RU 2006140958 A RU2006140958 A RU 2006140958A RU 2006140958/13 A RU2006140958/13 A RU 2006140958/13A RU 2006140958 A RU2006140958 A RU 2006140958A RU 2006140958 A RU2006140958 A RU 2006140958A
Authority
RU
Russia
Prior art keywords
serogroup
subject
proteins
immunizing
infection
Prior art date
Application number
RU2006140958/13A
Other languages
English (en)
Other versions
RU2378009C2 (ru
Inventor
Марио КОНТОРНИ (IT)
Марио Конторни
Марци ДЖУЛИАНИ (IT)
Марция ДЖУЛИАНИ
Мари граци ПИЦЦА (IT)
Марияграция ПИЦЦА
Original Assignee
Чирон С.Р.Л. (It)
Чирон С.Р.Л.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32344210&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RU2006140958(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Чирон С.Р.Л. (It), Чирон С.Р.Л. filed Critical Чирон С.Р.Л. (It)
Publication of RU2006140958A publication Critical patent/RU2006140958A/ru
Application granted granted Critical
Publication of RU2378009C2 publication Critical patent/RU2378009C2/ru

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/095Neisseria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Claims (5)

1. Способ иммунизации субъекта против инфекции Neisseria meningitidis серогруппы Y, предусматривающий введение субъекту композиции, содержащей один или несколько иммуногенных полипептидов.
2. Способ иммунизации субъекта против инфекции Neisseria meningitidis серогруппы Y, предусматривающий введение субъекту композиции, содержащей менингококковые OMV.
3. Применение одного или нескольких иммуногенных полипептидов для производства лекарственного средства для иммунизации субъекта против инфекции Neisseria meningitidis серогруппы Y.
4. Применение менингококковых OMV для производства лекарственного средства для иммунизации субъекта против инфекции Neisseria meningitidis серогруппы Y.
5. Способ или применение по любому из пп.1-4 для иммунизации субъекта также против инфекции N.meningitidis серогрупп А, В, С и/или W135.
RU2006140958/13A 2004-04-22 2005-04-22 Иммунизация против менингококков серогруппы y с помощью белков RU2378009C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0408977.7A GB0408977D0 (en) 2004-04-22 2004-04-22 Immunising against meningococcal serogroup Y using proteins
GB0408977.7 2004-04-22

Publications (2)

Publication Number Publication Date
RU2006140958A true RU2006140958A (ru) 2008-05-27
RU2378009C2 RU2378009C2 (ru) 2010-01-10

Family

ID=32344210

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2006140958/13A RU2378009C2 (ru) 2004-04-22 2005-04-22 Иммунизация против менингококков серогруппы y с помощью белков

Country Status (14)

Country Link
US (1) US10195264B2 (ru)
EP (1) EP1737486B2 (ru)
JP (2) JP4918479B2 (ru)
CN (1) CN1946420B (ru)
AU (1) AU2005235265A1 (ru)
BR (1) BRPI0510104A8 (ru)
CA (1) CA2566509C (ru)
CY (1) CY1114179T1 (ru)
ES (1) ES2401481T5 (ru)
GB (1) GB0408977D0 (ru)
MX (1) MXPA06012041A (ru)
PT (1) PT1737486E (ru)
RU (1) RU2378009C2 (ru)
WO (1) WO2005102384A2 (ru)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1228217E (pt) 1999-04-30 2013-01-28 Novartis Vaccines & Diagnostic Antígenos de neisseria conservados
NZ536676A (en) 1999-05-19 2006-11-30 Chiron S Combination neisserial compositions comprising amino acid sequences
AU3948801A (en) * 2000-02-28 2001-09-12 Chiron Spa Heterologous expression of neisserial proteins
MX339524B (es) 2001-10-11 2016-05-30 Wyeth Corp Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
CA2493977A1 (en) * 2002-08-02 2004-02-19 Glaxosmithkline Biologicals Sa Vaccine composition comprising lipooligosaccharide with reduced phase variability
EP2353608B1 (en) * 2002-10-11 2019-12-18 Novartis Vaccines and Diagnostics S.r.l. Polypeptide-vaccines for broad protection against hypervirulent meningococcal lineages
GB0408977D0 (en) * 2004-04-22 2004-05-26 Chiron Srl Immunising against meningococcal serogroup Y using proteins
NZ567978A (en) * 2005-11-04 2011-09-30 Novartis Vaccines & Diagnostic Influenza vaccine with reduced amount of oil-in-water emulsion as adjuvant
GB0524066D0 (en) * 2005-11-25 2006-01-04 Chiron Srl 741 ii
NZ569076A (en) 2005-12-22 2011-08-26 Glaxosmithkline Biolog Sa Vaccine comprising capsular polysaccharides conjugates from Streptococcus pneumoniae serotypes 19A and 19F
AR064642A1 (es) 2006-12-22 2009-04-15 Wyeth Corp Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi
DK2167121T3 (en) 2007-06-26 2015-11-23 Glaxosmithkline Biolog Sa A vaccine comprising Streptococcus pneumoniae kapselpolysaccharidkonjugater
RU2555757C2 (ru) * 2009-03-24 2015-07-10 Новартис Аг Комбинации менингококкового фактор н-связывающего белка и пневмококковых сахаридных конъюгатов
EP2411048B1 (en) 2009-03-24 2020-05-06 GlaxoSmithKline Biologicals SA Adjuvanting meningococcal factor h binding protein
CA2772104A1 (en) * 2009-08-27 2011-03-03 Novartis Ag Hybrid polypeptides including meningococcal fhbp sequences
EP2494865A4 (en) * 2009-09-01 2014-05-14 Aeon Medix Inc EXTRACELLULAR VESICLES OBTAINED FROM THE DARMFLORA, AND METHOD FOR SEARCHING FOR A DISEASE MODEL, VACCINE AND CANDIDATE AND DIAGNOSTIC METHOD THEREFOR
WO2011027956A2 (ko) 2009-09-04 2011-03-10 주식회사이언메딕스 그람 양성 박테리아에서 유래한 세포밖 소포체 및 이를 이용한 질병 모델
TR201802933T4 (tr) 2010-03-30 2018-03-21 Childrens Hospital & Res Center At Oakland Özellikleri değiştirilmiş faktör h bağlama proteinleri (fhbp) ve bunların kullanım yöntemi.
PT3246044T (pt) 2010-08-23 2021-02-15 Wyeth Llc Formulações estáveis de antigénios de rlp2086 de neisseria meningitidis
NZ607224A (en) 2010-09-10 2014-11-28 Wyeth Llc Non-lipidated variants of neisseria meningitidis orf2086 antigens
RU2665841C2 (ru) 2012-03-09 2018-09-04 Пфайзер Инк. Композиции neisseria meningitidis и способы их применения
SA115360586B1 (ar) 2012-03-09 2017-04-12 فايزر انك تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
WO2013186753A1 (en) 2012-06-14 2013-12-19 Novartis Ag Vaccines for serogroup x meningococcus
CN104736563A (zh) 2012-07-27 2015-06-24 国家健康与医学研究院 Cd147作为受体用于脑膜炎球菌至血管内皮的菌毛介导的粘附
CA2903716C (en) 2013-03-08 2019-04-09 Pfizer Inc. Immunogenic fusion polypeptides
KR20180099912A (ko) 2013-09-08 2018-09-05 화이자 인코포레이티드 나이세리아 메닌지티디스 조성물 및 그의 방법
NZ729206A (en) * 2014-07-23 2022-07-01 Children’S Hospital & Res Center At Oakland Factor h binding protein variants and methods of use thereof
CN107249626A (zh) 2015-02-19 2017-10-13 辉瑞大药厂 脑膜炎奈瑟球菌组合物及其方法
AU2017321039B2 (en) 2016-09-02 2021-03-18 Glaxosmithkline Biologicals Sa Vaccines for Neisseria gonorrhoeae
AU2018215585B2 (en) 2017-01-31 2022-03-17 Pfizer Inc. Neisseria meningitidis compositions and methods thereof

Family Cites Families (94)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4309095A (en) 1980-11-03 1982-01-05 Buckley Frederick P Camera mounting device
US4356170A (en) 1981-05-27 1982-10-26 Canadian Patents & Development Ltd. Immunogenic polysaccharide-protein conjugates
US4673574A (en) 1981-08-31 1987-06-16 Anderson Porter W Immunogenic conjugates
US4459286A (en) 1983-01-31 1984-07-10 Merck & Co., Inc. Coupled H. influenzae type B vaccine
US4663160A (en) 1983-03-14 1987-05-05 Miles Laboratories, Inc. Vaccines for gram-negative bacteria
US4761283A (en) 1983-07-05 1988-08-02 The University Of Rochester Immunogenic conjugates
US4808700A (en) 1984-07-09 1989-02-28 Praxis Biologics, Inc. Immunogenic conjugates of non-toxic E. coli LT-B enterotoxin subunit and capsular polymers
EP0273116A3 (en) 1986-10-09 1990-05-02 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Gonococcal and meningococcal polypeptides, vaccines and diagnostics
NO882936D0 (no) * 1987-07-07 1988-07-01 Nl Mini Welzijn Gesund Cultur Flerverdig meningokokkvaksine.
RU2023448C1 (ru) 1987-07-30 1994-11-30 Сентро Насьональ Де Биопрепарадос Способ получения вакцины против различных патогенных серотипов менингита нейссера группы в
US4835621A (en) 1987-11-04 1989-05-30 Black John W Gun mounted video camera
NL8802046A (nl) 1988-08-18 1990-03-16 Gen Electric Polymeermengsel met polyester en alkaansulfonaat, daaruit gevormde voorwerpen.
EP0449958B9 (en) 1988-12-19 2003-05-28 American Cyanamid Company Meningococcal class 1 outer-membrane protein vaccine
NL8803111A (nl) 1988-12-19 1990-07-16 Nederlanden Staat Multivalent meningococcen klasse i buitenmembraaneiwit vaccin.
DK130889A (da) 1989-03-17 1990-09-18 Mogens Kilian Immunoglobulin a1-proteaser (iga1-proteaser), fremgangsmaade til genteknologisk fremstilling af saadanne enzymer samt vaccine indeholdende enzymerne og fragmenter deraf til immunisering mod bakteriel meningitis og andre sygdomme fremkaldt af iga1-protease-producerende bakterier
EP0467714A1 (en) 1990-07-19 1992-01-22 Merck & Co. Inc. The class II protein of the outer membrane of neisseria meningitidis
US5020262A (en) 1990-09-04 1991-06-04 Pena Louis T Camera mount for rifle scopes
ES2127217T3 (es) 1991-03-14 1999-04-16 Imclone Systems Inc Epitopos de porina hibridos de recombinacion.
FR2692592B1 (fr) 1992-06-19 1995-03-31 Pasteur Merieux Serums Vacc Fragments d'ADN codant pour les sous-unités du récepteur de la transferrine de Neisseria meningitidis et procédés les exprimant.
NL9201716A (nl) 1992-10-02 1994-05-02 Nederlanden Staat Buitenmembraanvesikel dat voorzien is van een groep polypeptiden welke ten minste de immuunwerking van aan membraan gebonden buitenmembraaneiwitten (OMP's) hebben, werkwijze ter bereiding ervan alsmede een vaccin dat een dergelijk buitenmembraanvesikel omvat.
US5439808A (en) 1993-07-23 1995-08-08 North American Vaccine, Inc. Method for the high level expression, purification and refolding of the outer membrane group B porin proteins from Neisseria meningitidis
FR2720408B1 (fr) 1994-05-31 1996-08-14 Pasteur Merieux Serums Vacc Fragments Tbp2 de Neisseria meningitidis.
IL117483A (en) 1995-03-17 2008-03-20 Bernard Brodeur MENINGITIDIS NEISSERIA shell protein is resistant to proteinase K.
US6180111B1 (en) 1995-05-18 2001-01-30 University Of Maryland Vaccine delivery system
FR2739624B1 (fr) 1995-10-10 1997-12-05 Pasteur Merieux Serums Vacc Nouvelle sous-unite tbp2 de neisseria meningitidis
JP4162267B2 (ja) 1996-08-27 2008-10-08 カイロン コーポレイション Neisseria meningitidis血清型B複合糖質およびその使用法
US6472518B1 (en) 1996-10-24 2002-10-29 Centers For Disease Control And Prevention, As Represented By The Secretary, Department Of Health And Human Services Invasion associated genes from Neisseria meningitidis serogroup B
GB9711964D0 (en) 1997-06-09 1997-08-06 Medical Res Council Live attenuated vaccines
EP1900818A3 (en) 1997-11-06 2008-06-11 Novartis Vaccines and Diagnostics S.r.l. Neisserial antigens
US6914131B1 (en) * 1998-10-09 2005-07-05 Chiron S.R.L. Neisserial antigens
US5887375A (en) 1997-11-19 1999-03-30 Watson; Jerry Wade Camera mount for firearms
GB9726398D0 (en) 1997-12-12 1998-02-11 Isis Innovation Polypeptide and coding sequences
ES2333071T5 (es) 1998-01-14 2015-08-17 Novartis Vaccines And Diagnostics S.R.L. Antígenos de Neisseria meningitidis
ES2294629T3 (es) 1998-05-01 2008-04-01 Novartis Vaccines And Diagnostics, Inc. Antigenos de neisseria y composiciones.
US20070026021A1 (en) * 1998-05-01 2007-02-01 Chiron S.R.I. Neisseria meningitidis antigens and compositions
AU1202200A (en) 1998-10-09 2000-05-01 Chiron Corporation Neisseria genomic sequences and methods of their use
US6146902A (en) 1998-12-29 2000-11-14 Aventis Pasteur, Inc. Purification of polysaccharide-protein conjugate vaccines by ultrafiltration with ammonium sulfate solutions
US6425697B1 (en) 1999-03-17 2002-07-30 Jeff C. Potts Universal camera mounting assembly
PT1228217E (pt) 1999-04-30 2013-01-28 Novartis Vaccines & Diagnostic Antígenos de neisseria conservados
ES2323845T3 (es) 1999-04-30 2009-07-27 Novartis Vaccines And Diagnostics, Inc. Secuencias genomicas de neisseria y procedimientos de uso.
NZ536676A (en) 1999-05-19 2006-11-30 Chiron S Combination neisserial compositions comprising amino acid sequences
US6192614B1 (en) 1999-07-23 2001-02-27 Daniel Cliburn Video mounting system for firearm
GB9918319D0 (en) 1999-08-03 1999-10-06 Smithkline Beecham Biolog Vaccine composition
ES2539951T3 (es) 1999-10-29 2015-07-07 Novartis Vaccines And Diagnositics S.R.L. Péptidos antigénicos de Neisseria
GB9928196D0 (en) 1999-11-29 2000-01-26 Chiron Spa Combinations of B, C and other antigens
EP1741784B1 (en) * 1999-11-29 2010-03-10 Novartis Vaccines and Diagnostics S.r.l. 85kDa neisserial antigen
EP2281571A3 (en) * 2000-01-17 2012-04-25 Novartis Vaccines and Diagnostics S.r.l. Outer membrane vesicle (omv) vaccine comprising n. meningitidids serogroup b outer membrane proteins
CN102417537A (zh) 2000-01-25 2012-04-18 昆士兰大学 包含脑膜炎奈瑟氏球菌表面抗原NhhA的保守区域的蛋白质
AU3948801A (en) 2000-02-28 2001-09-12 Chiron Spa Heterologous expression of neisserial proteins
WO2002009643A2 (en) 2000-07-27 2002-02-07 Children's Hospital & Research Center At Oakland Vaccines for broad spectrum protection against diseases caused by neisseria meningitidis
GB0103170D0 (en) 2001-02-08 2001-03-28 Smithkline Beecham Biolog Vaccine composition
ES2544979T3 (es) 2001-01-23 2015-09-07 Sanofi Pasteur Inc. Vacuna de conjugado de polisacárido-CRM197 meningocócica tri- o tetravalente
GB0103171D0 (en) 2001-02-08 2001-03-28 Smithkline Beecham Biolog Vaccine composition
GB0115176D0 (en) 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
RU2323002C2 (ru) * 2001-07-26 2008-04-27 Чирон Срл. Вакцины, содержащие алюминиевые адъюванты и гистидин
GB0118249D0 (en) * 2001-07-26 2001-09-19 Chiron Spa Histidine vaccines
GB0121591D0 (en) 2001-09-06 2001-10-24 Chiron Spa Hybrid and tandem expression of neisserial proteins
DE60236596D1 (de) * 2001-07-27 2010-07-15 Novartis Vaccines & Diagnostic Antikörper gegen das meningokokken adhäsin app
AR045702A1 (es) 2001-10-03 2005-11-09 Chiron Corp Composiciones de adyuvantes.
MX339524B (es) 2001-10-11 2016-05-30 Wyeth Corp Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
GB0220197D0 (en) 2002-08-30 2002-10-09 Univ Utrecht Refolding method
CA2493977A1 (en) 2002-08-02 2004-02-19 Glaxosmithkline Biologicals Sa Vaccine composition comprising lipooligosaccharide with reduced phase variability
US7785608B2 (en) * 2002-08-30 2010-08-31 Wyeth Holdings Corporation Immunogenic compositions for the prevention and treatment of meningococcal disease
EP2353608B1 (en) * 2002-10-11 2019-12-18 Novartis Vaccines and Diagnostics S.r.l. Polypeptide-vaccines for broad protection against hypervirulent meningococcal lineages
GB0227346D0 (en) 2002-11-22 2002-12-31 Chiron Spa 741
US20070148729A1 (en) 2003-01-15 2007-06-28 Farley John E Methods for increasing neisseria protein expression and compositions thereof
PT1587537E (pt) 2003-01-30 2012-05-30 Novartis Ag Vacinas injetáveis contra múltiplos serogrupos meningocócicos
WO2004094596A2 (en) 2003-04-16 2004-11-04 Wyeth Holdings Corporation Novel immunogenic compositions for the prevention and treatment of meningococcal disease
US7731967B2 (en) 2003-04-30 2010-06-08 Novartis Vaccines And Diagnostics, Inc. Compositions for inducing immune responses
GB0315021D0 (en) * 2003-06-26 2003-07-30 Chiron Srl Immunogenic gonococcal compositions
EP2277538A1 (en) * 2003-10-02 2011-01-26 Novartis Vaccines and Diagnostics S.r.l. Combined meningitis vaccines
GB0408977D0 (en) * 2004-04-22 2004-05-26 Chiron Srl Immunising against meningococcal serogroup Y using proteins
GB0409748D0 (en) 2004-04-30 2004-06-09 Chiron Srl Lactoferrin cleavage
GB0419408D0 (en) 2004-09-01 2004-10-06 Chiron Srl 741 chimeric polypeptides
GB0419627D0 (en) * 2004-09-03 2004-10-06 Chiron Srl Immunogenic bacterial vesicles with outer membrane proteins
HUE033196T2 (en) 2005-01-27 2017-11-28 Children's Hospital & Res Center At Oakland GNA1870-based vesicle vaccines for broad-spectrum protection against diseases caused by Neisseria meningitidis
EP2201961B1 (en) * 2005-06-27 2018-01-24 GlaxoSmithKline Biologicals S.A. Immunogenic composition
GB0524066D0 (en) * 2005-11-25 2006-01-04 Chiron Srl 741 ii
TW200806315A (en) 2006-04-26 2008-02-01 Wyeth Corp Novel formulations which stabilize and inhibit precipitation of immunogenic compositions
RU2450019C2 (ru) * 2006-06-29 2012-05-10 Новартис Аг Полипептиды из neisseria meningitidis
US7491517B2 (en) * 2006-07-19 2009-02-17 Jeeri R Reddy Method of producing meningococcal meningitis vaccine for Neisseria meningitidis serotypes A,C,Y, and W-135
AR064642A1 (es) 2006-12-22 2009-04-15 Wyeth Corp Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi
WO2008125985A2 (en) 2007-04-11 2008-10-23 Novartis Ag Blocking interaction between pathogen factors and factor h to inhibit hemorrhagic syndromes
NZ581367A (en) 2007-06-04 2012-05-25 Novartis Ag Formulation of meningitis vaccines containing haemophilus influenzae and neisseria meningitidis
AU2009215364B2 (en) 2008-02-21 2014-09-18 Glaxosmithkline Biologicals S.A. Meningococcal fHBP polypeptides
EP2265640B1 (en) 2008-03-10 2015-11-04 Children's Hospital & Research Center at Oakland Chimeric factor h binding proteins (fhbp) containing a heterologous b domain and methods of use
EP2297578A2 (en) * 2008-05-19 2011-03-23 Novartis AG Vaccine assays
WO2010028096A2 (en) 2008-09-03 2010-03-11 Children's Hospital & Research Center At Oakland Peptides presenting an epitope of an a domain of factor h binding protein and methods of use
IT1394288B1 (it) 2008-09-12 2012-06-06 Novartis Vaccines & Diagnostic Immunogeni di proteine che legano il fattore h.
GB0819633D0 (en) 2008-10-25 2008-12-03 Isis Innovation Composition
EP2411048B1 (en) 2009-03-24 2020-05-06 GlaxoSmithKline Biologicals SA Adjuvanting meningococcal factor h binding protein
EP2544714A1 (en) 2010-03-10 2013-01-16 GlaxoSmithKline Biologicals S.A. Vaccine composition
TR201802933T4 (tr) 2010-03-30 2018-03-21 Childrens Hospital & Res Center At Oakland Özellikleri değiştirilmiş faktör h bağlama proteinleri (fhbp) ve bunların kullanım yöntemi.
ES2759484T3 (es) 2010-09-10 2020-05-11 Glaxosmithkline Biologicals Sa Meningococo que sobreexpresa NadA y/o NHBA y vesículas de la membrana externa derivadas del mismo

Also Published As

Publication number Publication date
WO2005102384A3 (en) 2006-03-23
CN1946420A (zh) 2007-04-11
CN1946420B (zh) 2011-02-16
JP2007533729A (ja) 2007-11-22
JP2011105777A (ja) 2011-06-02
EP1737486B1 (en) 2013-02-27
GB0408977D0 (en) 2004-05-26
JP4918479B2 (ja) 2012-04-18
CY1114179T1 (el) 2016-08-31
US20100143418A1 (en) 2010-06-10
RU2378009C2 (ru) 2010-01-10
PT1737486E (pt) 2013-05-15
CA2566509A1 (en) 2005-11-03
EP1737486A2 (en) 2007-01-03
ES2401481T5 (es) 2023-05-16
CA2566509C (en) 2018-07-17
ES2401481T3 (es) 2013-04-22
BRPI0510104A8 (pt) 2018-04-03
BRPI0510104A (pt) 2007-09-25
MXPA06012041A (es) 2007-01-25
WO2005102384A2 (en) 2005-11-03
AU2005235265A1 (en) 2005-11-03
EP1737486B2 (en) 2022-12-28
US10195264B2 (en) 2019-02-05

Similar Documents

Publication Publication Date Title
RU2006140958A (ru) Иммунизация против менингококков серогруппы y с помощью белков
JP2007533729A5 (ru)
EA200801368A1 (ru) Конъюгатные вакцины
DK1755662T3 (da) Kombinerede meningokokkonjugater med fælles bærerprotein
RU2007130774A (ru) Вакцинация менингококковыми конъюгатами
EP2348036A3 (en) Novel immunogenic compositions for the prevention and treatment of meningococcal disease
BRPI0818545A2 (pt) formulações de vacinais meningocócicas
RU2006142158A (ru) Вакцинация менингококковыми конъюгатами
RU2007102016A (ru) Пространственный анализ конъюгатов сахаридов с помощью gpc и sec-mals
ATE552844T1 (de) Injizierbarer impfstoff gegen multiple meningokokken-serogruppen
HUP0302999A2 (hu) Multivalens, meningokokkusz-eredetû poliszaccharid és fehérje konjugátumát tartalmazó vakcina
EP1379272A4 (en) MOLECULAR MIMETICS OF MENINGOKOKEN B EPITOPES THAT MAKE THE FORMATION OF FUNCTIONALLY EFFECTIVE ANTIBODIES
JP2007516219A5 (ru)
BRPI0411875A (pt) método de imunização contra os sorogrupos a e c de neisseria meningitidis
RU2015100889A (ru) Вакцины для менингококка серогруппы х
EA201591468A1 (ru) Способ лечения
WO2005023295A3 (en) Naturally processed immunodominant peptides derived from neisseria meningitidis porin a protein and their use

Legal Events

Date Code Title Description
MM4A The patent is invalid due to non-payment of fees

Effective date: 20180423