RU2005106841A - Эпитопы т-клеток в эритропоэтине - Google Patents

Эпитопы т-клеток в эритропоэтине Download PDF

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Publication number
RU2005106841A
RU2005106841A RU2005106841/13A RU2005106841A RU2005106841A RU 2005106841 A RU2005106841 A RU 2005106841A RU 2005106841/13 A RU2005106841/13 A RU 2005106841/13A RU 2005106841 A RU2005106841 A RU 2005106841A RU 2005106841 A RU2005106841 A RU 2005106841A
Authority
RU
Russia
Prior art keywords
molecule
epo
modified
considered
peptide
Prior art date
Application number
RU2005106841/13A
Other languages
English (en)
Russian (ru)
Inventor
Маттью БЕЙКЕР (GB)
Маттью БЕЙКЕР
Франсис Дж. КАРР (GB)
Франсис Дж. КАРР
Original Assignee
Мерк Патент ГмбХ (DE)
Мерк Патент Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Мерк Патент ГмбХ (DE), Мерк Патент Гмбх filed Critical Мерк Патент ГмбХ (DE)
Publication of RU2005106841A publication Critical patent/RU2005106841A/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
RU2005106841/13A 2002-08-09 2003-08-07 Эпитопы т-клеток в эритропоэтине RU2005106841A (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02017914.9 2002-08-09
EP02017914 2002-08-09

Publications (1)

Publication Number Publication Date
RU2005106841A true RU2005106841A (ru) 2005-10-27

Family

ID=31896824

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2005106841/13A RU2005106841A (ru) 2002-08-09 2003-08-07 Эпитопы т-клеток в эритропоэтине

Country Status (16)

Country Link
US (1) US20060035322A1 (es)
EP (1) EP1527094B1 (es)
JP (1) JP2006515161A (es)
KR (1) KR20060003853A (es)
CN (1) CN1675242A (es)
AT (1) ATE401344T1 (es)
AU (1) AU2003263201A1 (es)
BR (1) BR0313135A (es)
CA (1) CA2494963A1 (es)
DE (1) DE60322225D1 (es)
ES (1) ES2310684T3 (es)
MX (1) MXPA05001452A (es)
PL (1) PL372862A1 (es)
RU (1) RU2005106841A (es)
WO (1) WO2004018515A2 (es)
ZA (1) ZA200501974B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60332358D1 (de) * 2002-09-09 2010-06-10 Hanall Pharmaceutical Co Ltd Protease-resistente modifizierte interferon alpha polypeptide
WO2006029094A2 (en) * 2004-09-02 2006-03-16 Xencor, Inc. Erythropoietin derivatives with altered immunogenicity
US8653028B2 (en) * 2005-04-29 2014-02-18 Rui Rong Yuan Erythropoietin-derived short peptide and its mimics as immuno/inflammatory modulators
US9345745B2 (en) 2005-04-29 2016-05-24 Bo Wang Methods for treating inflammatory disorders and traumatic brain injury using stabilized non-hematopoietic EPO short peptides
EP2377884A1 (en) * 2005-05-10 2011-10-19 Neoloch Aps Neuritogenic peptides
JP2010510794A (ja) 2006-11-28 2010-04-08 ハナル ファーマシューティカル カンパニー リミテッド 修飾型エリスロポエチンポリペプチド及びこの治療用用途
US20090010966A1 (en) * 2007-06-21 2009-01-08 Angelica Therapeutics, Inc. Modified diphtheria toxins
EP2268297A4 (en) * 2008-02-29 2011-11-16 Angelica Therapeutics Inc MODIFIED TOXINS
US10059750B2 (en) 2013-03-15 2018-08-28 Angelica Therapeutics, Inc. Modified toxins
JP6479789B2 (ja) * 2013-07-17 2019-03-13 アライム ファーマシューティカルズ，インコーポレーテッド 組織の損傷に関連した疾患及び障害を予防及び治療する、組織保護ペプチド及びペプチド類似体
CN106554395B (zh) * 2015-09-30 2019-08-16 天津药物研究院有限公司 一种长效促红细胞生成素模拟肽及其制备方法和应用
AR113091A1 (es) * 2018-09-27 2020-01-22 Univ Nacional Del Litoral Eritropoyetina humana modificada
EP4208186A1 (en) * 2020-09-04 2023-07-12 Dompe' Farmaceutici SpA Peptides endowed with angiogenic activity
EP3964225A1 (en) * 2020-09-04 2022-03-09 Dompe' Farmaceutici S.P.A. Peptides endowed with angiogenic activity

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4954437A (en) * 1986-09-15 1990-09-04 Integrated Genetics, Inc. Cell encoding recombinant human erythropoietin
US4835260A (en) * 1987-03-20 1989-05-30 Genetics Institute, Inc. Erythropoietin composition
DE3924746A1 (de) * 1989-07-26 1991-01-31 Behringwerke Ag Erythropoietin (epo)-peptide und dagegen gerichtete antikoerper
NZ244778A (en) * 1991-10-21 1994-03-25 Ortho Pharma Corp Peg imidates and protein derivatives thereof
EP1051432B1 (en) * 1998-12-08 2007-01-24 Biovation Limited Method for reducing immunogenicity of proteins
CA2288341C (en) * 1998-12-17 2005-01-04 Pfizer Products Inc. Erythropoietin in the treatment of domestic and livestock animals for anemia
CN1454097A (zh) * 2000-09-08 2003-11-05 格莱风治疗公司 聚合物修饰的合成的蛋白质类
PL362396A1 (en) * 2001-02-06 2004-11-02 Merck Patent Gmbh Modified erythropoietin (epo) with reduced immunogenicity
HUP0303199A2 (hu) * 2001-02-19 2003-12-29 Merck Patent Gmbh Eljárás T-sejt-epitópok azonosítására és csökkentett immunogenitású molekulák előállítására

Also Published As

Publication number Publication date
ES2310684T3 (es) 2009-01-16
WO2004018515A3 (en) 2004-06-03
EP1527094B1 (en) 2008-07-16
KR20060003853A (ko) 2006-01-11
WO2004018515A2 (en) 2004-03-04
CA2494963A1 (en) 2004-03-04
BR0313135A (pt) 2005-07-05
AU2003263201A1 (en) 2004-03-11
CN1675242A (zh) 2005-09-28
PL372862A1 (en) 2005-08-08
US20060035322A1 (en) 2006-02-16
DE60322225D1 (en) 2008-08-28
ZA200501974B (en) 2006-03-29
ATE401344T1 (de) 2008-08-15
MXPA05001452A (es) 2005-06-06
JP2006515161A (ja) 2006-05-25
EP1527094A2 (en) 2005-05-04

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Legal Events

Date Code Title Description
FA92 Acknowledgement of application withdrawn (lack of supplementary materials submitted)

Effective date: 20071017