RS65176B1 - Kombinacija pentacikličnih triterpena i hidroksitirozola i njihovih derivata - Google Patents

Kombinacija pentacikličnih triterpena i hidroksitirozola i njihovih derivata

Info

Publication number
RS65176B1
RS65176B1 RS20240106A RSP20240106A RS65176B1 RS 65176 B1 RS65176 B1 RS 65176B1 RS 20240106 A RS20240106 A RS 20240106A RS P20240106 A RSP20240106 A RS P20240106A RS 65176 B1 RS65176 B1 RS 65176B1
Authority
RS
Serbia
Prior art keywords
hydroxytyrosol
derivatives
combination
pentacyclic triterpenes
pentacyclic
Prior art date
Application number
RS20240106A
Other languages
English (en)
Inventor
Fernández José Carlos Quintela
La Fuente García Esther De
Marco Pugliese
Aroca Pilar Mancera
Santafé Javier Bustos
Parrilla Juan Francisco Espinosa
Treserres Noemí Virgili
Battestini Blanca Wappenhans
Original Assignee
Natac Biotech S L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Natac Biotech S L filed Critical Natac Biotech S L
Publication of RS65176B1 publication Critical patent/RS65176B1/sr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/191—Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Mycology (AREA)
  • Polymers & Plastics (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Physiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
RS20240106A 2013-06-13 2014-06-12 Kombinacija pentacikličnih triterpena i hidroksitirozola i njihovih derivata RS65176B1 (sr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13171906.4A EP2813221A1 (en) 2013-06-13 2013-06-13 Combination of pentacyclic triterpenes and hydroxytyrosol and derivatives thereof
EP14730844.9A EP3007687B1 (en) 2013-06-13 2014-06-12 Combination of pentacyclic triterpenes and hydroxytyrosol and derivatives thereof
PCT/EP2014/062269 WO2014198842A1 (en) 2013-06-13 2014-06-12 Combination of pentacyclic triterpenes and hydroxytyrosol and derivatives thereof

Publications (1)

Publication Number Publication Date
RS65176B1 true RS65176B1 (sr) 2024-03-29

Family

ID=48607145

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20240106A RS65176B1 (sr) 2013-06-13 2014-06-12 Kombinacija pentacikličnih triterpena i hidroksitirozola i njihovih derivata

Country Status (10)

Country Link
US (1) US10376529B2 (sr)
EP (2) EP2813221A1 (sr)
JP (1) JP6441908B2 (sr)
CN (1) CN105530922B (sr)
CA (1) CA2915164A1 (sr)
ES (1) ES2970405T3 (sr)
HU (1) HUE065124T2 (sr)
PL (1) PL3007687T3 (sr)
RS (1) RS65176B1 (sr)
WO (1) WO2014198842A1 (sr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106581006B (zh) * 2015-10-16 2019-11-29 香港理工大学深圳研究院 三萜类化合物在制备治疗帕金森药物中的应用
JP2017178914A (ja) * 2016-03-31 2017-10-05 株式会社ニュートリション・アクト 脳機能改善及び向上のための組成物
CN106138016A (zh) * 2016-06-28 2016-11-23 西安交通大学 羟基酪醇在制备防治阿尔茨海默病的药物中的应用
CN106420765A (zh) * 2016-09-10 2017-02-22 浙江大学 山楂酸在制备治疗和预防中枢神经系统疾病药物中的用途
KR102665310B1 (ko) * 2016-10-27 2024-05-10 주식회사 엘지생활건강 베어바스코사이드를 포함하는 구강질환 예방 또는 치료용 조성물
KR101895554B1 (ko) * 2017-02-28 2018-09-05 경희대학교 산학협력단 올레아놀릭산을 포함하는 신경발달장애 또는 강박장애의 예방, 개선 또는 치료용 조성물
AU2018334467B2 (en) * 2017-09-14 2022-10-20 Phoenix Biotechnology, Inc. Method and improved neuroprotective composition for treating neurological conditions
WO2019077810A1 (ja) * 2017-10-17 2019-04-25 国立大学法人富山大学 ペリオスチン及びｐｋｍ２の分泌促進剤
CN110693893B (zh) * 2018-07-10 2023-11-03 香港大学 来自地黄的提取物作为多发性硬化症的治疗剂
CN109503695B (zh) * 2018-09-07 2020-05-22 南昌大学第一附属医院 熊果酸锂及其合成方法与在预防和治疗阿尔茨海默病中的应用
CN109303786B (zh) * 2018-11-27 2024-09-20 山东省药学科学院 一种耐缺氧的组合物及其应用
AU2020289909A1 (en) * 2019-06-12 2021-08-19 Tao Pharmaceutical (Suzhou) Co., Ltd Antihypertensive polyol compound and derivative thereof
CN112521286B (zh) * 2019-09-17 2021-12-28 西安交通大学 化合物3-羟基-3’,4’-二羟基-丁酸苯乙酯的制备方法和用途
US10995053B1 (en) * 2020-03-20 2021-05-04 Shaanxi University Of Science And Technology Hydroxytyrosol ursolic acid ester with antioxidant activity and methods of preparing the same
CN115361877A (zh) * 2020-03-31 2022-11-18 卢斯塔公司 饲料添加剂

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2111498B1 (es) 1996-07-25 1998-09-01 Univ Granada Procedimiento de aprovechamiento industrial de los acidos oleanolico y maslinico contenidos en los subproductos de la molturacion de la aceituna.
WO2001026670A1 (fr) 1999-10-14 2001-04-19 The Nisshin Oil Mills, Ltd. Agents de soin de la peau, agents anti-ages pour la peau, agents de blanchiment de la peau et preparations pour la peau, a usage externe
JP2001181198A (ja) 1999-10-14 2001-07-03 Nisshin Oil Mills Ltd:The 美肌剤、皮膚の抗老化剤、美白剤および皮膚外用剤
CA2480987C (en) * 2002-04-03 2011-06-14 Puleva Biotech, S.A. Natural products and derivatives thereof for protection against neurodegenerative diseases
ES2261088B1 (es) 2005-04-27 2007-12-01 Laboratorios Alcala Farma, S.L. Uso de hidroxitirosol en la prevencion y tratamiento del ictus cerebral isquemico.
ES2301336B1 (es) 2006-02-22 2009-05-01 Universidad De Granada Extracto de aceituna como pronutriente en alimentacion animal.
ES2286953B1 (es) 2006-05-18 2008-12-16 Universidad De Granada Formulacion de triterpenos naturales y biofenoles obtenidos del genero olea en liposomas.
JP5339373B2 (ja) * 2006-07-14 2013-11-13 ディーエスエム アイピー アセッツ ビー．ブイ． 組成物および炎症障害の治療、共治療または予防のためのその使用
DE102006062566A1 (de) * 2006-12-29 2008-07-03 Henkel Kgaa Kosmetische und dermatologische Zusammensetzungen gegen unreine Haut und/oder Akne
ES2311394B2 (es) * 2007-02-22 2009-10-21 Universidad De Granada Alimento funcional obtenido por reincorporacion de ingredientes naturales de la aceituna al aceite de oliva.
EP1982707A1 (en) 2007-04-18 2008-10-22 DSMIP Assets B.V. Use of hydroxytyrosol as anti-aging agent
ES2326065B1 (es) 2008-03-28 2010-07-08 Consejo Superior De Investigaciones Cientificas (Csic) Utilizacion de un triterpeno pentaciclico para la preparacion de una composicion farmaceutica destinada al tratamiento de la esclerosis multiple.
ES2333638B2 (es) 2009-07-29 2010-10-21 Universidad De Granada Uso del acido maslinico para el tratamiento de dolores de naturaleza nociceptiva, inflamatoria y neurogenica.
ES2395317B1 (es) * 2011-07-08 2014-04-16 Consejo Superior De Investigaciones Cientificas (Csic) Procedimiento para la obtención de extracto de hidroxitirosol, extracto mezcla de hidroxitirosol y 3,4-dihidroxifenilglicol, y extracto de acetato de hidroxitirosilo, a partir de subproductos del olivo y su purificación.

Also Published As

Publication number Publication date
HUE065124T2 (hu) 2024-05-28
WO2014198842A1 (en) 2014-12-18
US20160143930A1 (en) 2016-05-26
EP3007687B1 (en) 2023-11-15
EP3007687A1 (en) 2016-04-20
EP3007687C0 (en) 2023-11-15
US10376529B2 (en) 2019-08-13
JP6441908B2 (ja) 2018-12-19
CA2915164A1 (en) 2014-12-18
EP2813221A1 (en) 2014-12-17
ES2970405T3 (es) 2024-05-28
CN105530922B (zh) 2018-07-03
JP2016521717A (ja) 2016-07-25
CN105530922A (zh) 2016-04-27
PL3007687T3 (pl) 2024-04-08

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