RS59850B1 - Bardoksolon metil za lečenje gojaznosti - Google Patents
Bardoksolon metil za lečenje gojaznostiInfo
- Publication number
- RS59850B1 RS59850B1 RS20200073A RSP20200073A RS59850B1 RS 59850 B1 RS59850 B1 RS 59850B1 RS 20200073 A RS20200073 A RS 20200073A RS P20200073 A RSP20200073 A RS P20200073A RS 59850 B1 RS59850 B1 RS 59850B1
- Authority
- RS
- Serbia
- Prior art keywords
- obesity
- treatment
- bardoxolone methyl
- bardoxolone
- methyl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Nutrition Science (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Child & Adolescent Psychology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Physiology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32327610P | 2010-04-12 | 2010-04-12 | |
US38909010P | 2010-10-01 | 2010-10-01 | |
PCT/US2011/032156 WO2011130302A2 (en) | 2010-04-12 | 2011-04-12 | Method of treating obesity using antioxidant inflammation modulators |
EP11715645.5A EP2558105B1 (en) | 2010-04-12 | 2011-04-12 | Bardoxolone methyl for the treatment of obesity |
Publications (1)
Publication Number | Publication Date |
---|---|
RS59850B1 true RS59850B1 (sr) | 2020-02-28 |
Family
ID=44259866
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RS20200073A RS59850B1 (sr) | 2010-04-12 | 2011-04-12 | Bardoksolon metil za lečenje gojaznosti |
Country Status (29)
Country | Link |
---|---|
US (2) | US10105372B2 (sr) |
EP (1) | EP2558105B1 (sr) |
JP (1) | JP5990160B2 (sr) |
KR (1) | KR101819699B1 (sr) |
CN (1) | CN102939089B (sr) |
AU (1) | AU2011240690C1 (sr) |
BR (1) | BR112012026112B1 (sr) |
CA (1) | CA2795320C (sr) |
CL (1) | CL2012002859A1 (sr) |
CY (1) | CY1122480T1 (sr) |
DK (1) | DK2558105T3 (sr) |
EA (1) | EA026567B1 (sr) |
ES (1) | ES2768204T3 (sr) |
HR (1) | HRP20192291T1 (sr) |
HU (1) | HUE047994T2 (sr) |
IL (1) | IL222273B (sr) |
LT (1) | LT2558105T (sr) |
ME (1) | ME03713B (sr) |
MX (1) | MX357596B (sr) |
MY (1) | MY163031A (sr) |
NZ (1) | NZ602826A (sr) |
PL (1) | PL2558105T3 (sr) |
PT (1) | PT2558105T (sr) |
RS (1) | RS59850B1 (sr) |
SG (2) | SG10201808661XA (sr) |
SI (1) | SI2558105T1 (sr) |
TW (1) | TWI558724B (sr) |
WO (1) | WO2011130302A2 (sr) |
ZA (1) | ZA201207518B (sr) |
Families Citing this family (33)
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US6326507B1 (en) | 1998-06-19 | 2001-12-04 | Trustees Of Dartmouth College | Therapeutic compounds and methods of use |
TWI621624B (zh) | 2008-01-11 | 2018-04-21 | 瑞塔醫藥有限責任公司 | 合成的三萜系化合物及其使用於治療疾病之方法 |
KR20110010611A (ko) | 2008-04-18 | 2011-02-01 | 리타 파마슈티컬스 잉크. | 산화방지성 염증 조절제 c-17 일치된 올레아놀산 유도체 |
CA2721665C (en) | 2008-04-18 | 2017-01-24 | Reata Pharmaceuticals, Inc. | Compounds including an anti-inflammatory pharmacore and methods of use |
MX2010011437A (es) | 2008-04-18 | 2010-12-20 | Reata Pharmaceuticals Inc | Moduladores antioxidantes de inflamacion: derivados del acido oleanolico con saturacion en el anillo c. |
DK2276493T3 (da) | 2008-04-18 | 2019-01-02 | Reata Pharmaceuticals Inc | Antioxidative inflammationsmodulatorer: oleanolsyrederivater med amino- og andre modifikationer ved c-17 |
ES2449396T3 (es) | 2008-07-22 | 2014-03-19 | Trustees Of Dartmouth College | Cianoenonas monocíclicas y métodos de uso de las mismas |
MX357596B (es) * | 2010-04-12 | 2018-07-16 | Reata Pharmaceuticals Inc | Método para tratar obesidad utilizando moduladores de inflamación con antioxidantes. |
EA025568B1 (ru) | 2010-12-17 | 2017-01-30 | Рита Фармасьютикалз, Инк. | Пиразолильные и пиримидинильные трициклические еноны в качестве антиоксидантных модуляторов воспаления |
MX348862B (es) | 2011-03-11 | 2017-07-03 | Reata Pharmaceuticals Inc | Derivados c4-monometil triterpenoides y sus metodos de uso. |
KR101174701B1 (ko) * | 2011-12-29 | 2012-08-17 | 서울대학교산학협력단 | 진저레논 에이를 포함하는 비만 예방용 식품 조성물, 비만 치료용 약학조성물 및 비만 치료용 동물용 의약품 |
PL2841445T3 (pl) | 2012-04-27 | 2017-10-31 | Reata Pharmaceuticals Inc | Pochodne 2,2-difluoropropionamidowe bardoksolonu metylu, formy polimorficzne oraz sposoby ich stosowania |
US9556222B2 (en) | 2012-06-15 | 2017-01-31 | Reata Pharmaceuticals, Inc. | A-ring epoxidized triterpenoid-based anti-inflammation modulators and methods of use thereof |
WO2014040073A1 (en) | 2012-09-10 | 2014-03-13 | Reata Pharmaceuticals, Inc. | C13-hydroxy derivatives of oleanolic acid and methods of use thereof |
CA2884400A1 (en) * | 2012-09-10 | 2014-03-13 | Abbvie Inc. | Glycyrrhetinic acid derivatives and methods of use thereof |
US9512094B2 (en) | 2012-09-10 | 2016-12-06 | Reata Pharmaceuticals, Inc. | C17-heteroaryl derivatives of oleanolic acid and methods of use thereof |
SI2892912T1 (sl) * | 2012-09-10 | 2019-07-31 | Reata Pharmaceuticals, Inc. | C17-alkandiilni in alkendiilni derivati oleanolne kisline in postopki njihove uporabe |
RU2768868C2 (ru) | 2012-09-27 | 2022-03-25 | Дзе Чилдрен'З Медикал Сентер Корпорейшн | Соединения, предназначенные для лечения ожирения, и способы их применения |
EP2977381B1 (en) | 2013-03-19 | 2018-09-26 | Daiichi Sankyo Company, Limited | Terpenoid derivative |
AR096046A1 (es) | 2013-04-24 | 2015-12-02 | Abbvie Inc | Derivados de 2,2-difluoropropanamida de metil bardoxolona, formas polimórficas y métodos de uso |
IL285832B2 (en) * | 2013-08-23 | 2024-01-01 | Reata Pharmaceuticals Inc | Methods for the treatment and prevention of impaired functioning of the endothelium using brodoxolone methyl or its analogs |
WO2015112792A1 (en) | 2014-01-24 | 2015-07-30 | Abbvie Inc. | Aryl and arylalkyl substituted pyrazolyl and pyrimidinyl tricyclic enones as antioxidant inflammation modulators |
JP6716468B2 (ja) | 2014-05-05 | 2020-07-01 | ザ ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム | 肥満、糖尿病、または癌を治療するためのウルソル酸および/またはレスベラトロールを含む方法および組成物 |
KR20170055482A (ko) | 2014-09-10 | 2017-05-19 | 다이이찌 산쿄 가부시키가이샤 | 안질환 치료용 및 예방용 서방성 의약 조성물 |
KR20240035818A (ko) | 2015-02-12 | 2024-03-18 | 리아타 파마슈티컬즈, 아이엔씨. | 항산화 염증 조절제로서의 이미다졸릴 트리사이클릭 에논 |
CN105017374B (zh) * | 2015-07-20 | 2017-03-01 | 山西大学 | 一种齐墩果酸内酯类衍生物及其制备方法和应用 |
US20170056373A1 (en) * | 2015-09-01 | 2017-03-02 | Syracuse University | Ghrelin o-acyltransferase inhibitors |
WO2017053868A1 (en) | 2015-09-23 | 2017-03-30 | Reata Pharmaceutical, Inc. | C4-modified oleanolic acid derivatives for inhibition of il-17 and other uses |
EP3509699A4 (en) * | 2016-09-08 | 2020-05-06 | Regenera Pharma Ltd. | COMPOSITIONS WITH TRITER PENOIDS AND USES THEREOF FOR TREATING OPTICAL NEUROPATHY |
JP6633812B2 (ja) | 2016-11-08 | 2020-01-22 | リアタ ファーマシューティカルズ インコーポレイテッド | バルドキソロンメチルまたはその類似体を使用してアルポート症候群を処置する方法 |
TWI831738B (zh) | 2016-12-16 | 2024-02-11 | 美商瑞塔醫藥有限責任公司 | 用於抑制RORγ及其他用途的嘧啶三環烯酮衍生物 |
MX2020013692A (es) | 2018-06-15 | 2021-02-26 | Reata Pharmaceuticals Inc | Compuestos de pirazol e imidazol para la inhibicion de il-17 y rorgamma. |
US20210353612A1 (en) * | 2020-04-29 | 2021-11-18 | BioAge Labs, Inc. | Hypoxia-inducible factor prolyl hydroxylase inhibitors for treating aging-related conditions |
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KR20110010611A (ko) | 2008-04-18 | 2011-02-01 | 리타 파마슈티컬스 잉크. | 산화방지성 염증 조절제 c-17 일치된 올레아놀산 유도체 |
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CA2721665C (en) | 2008-04-18 | 2017-01-24 | Reata Pharmaceuticals, Inc. | Compounds including an anti-inflammatory pharmacore and methods of use |
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MX2010011437A (es) * | 2008-04-18 | 2010-12-20 | Reata Pharmaceuticals Inc | Moduladores antioxidantes de inflamacion: derivados del acido oleanolico con saturacion en el anillo c. |
ES2449396T3 (es) | 2008-07-22 | 2014-03-19 | Trustees Of Dartmouth College | Cianoenonas monocíclicas y métodos de uso de las mismas |
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2011
- 2011-04-12 MX MX2012011892A patent/MX357596B/es active IP Right Grant
- 2011-04-12 EP EP11715645.5A patent/EP2558105B1/en active Active
- 2011-04-12 AU AU2011240690A patent/AU2011240690C1/en active Active
- 2011-04-12 NZ NZ602826A patent/NZ602826A/en unknown
- 2011-04-12 PT PT117156455T patent/PT2558105T/pt unknown
- 2011-04-12 SI SI201131840T patent/SI2558105T1/sl unknown
- 2011-04-12 ME MEP-2020-4A patent/ME03713B/me unknown
- 2011-04-12 LT LTEP11715645.5T patent/LT2558105T/lt unknown
- 2011-04-12 HU HUE11715645A patent/HUE047994T2/hu unknown
- 2011-04-12 CA CA2795320A patent/CA2795320C/en active Active
- 2011-04-12 SG SG10201808661XA patent/SG10201808661XA/en unknown
- 2011-04-12 ES ES11715645T patent/ES2768204T3/es active Active
- 2011-04-12 MY MYPI2012004530A patent/MY163031A/en unknown
- 2011-04-12 PL PL11715645T patent/PL2558105T3/pl unknown
- 2011-04-12 RS RS20200073A patent/RS59850B1/sr unknown
- 2011-04-12 CN CN201180028997.6A patent/CN102939089B/zh active Active
- 2011-04-12 JP JP2013505061A patent/JP5990160B2/ja active Active
- 2011-04-12 US US13/085,338 patent/US10105372B2/en active Active
- 2011-04-12 KR KR1020127029558A patent/KR101819699B1/ko active IP Right Grant
- 2011-04-12 WO PCT/US2011/032156 patent/WO2011130302A2/en active Application Filing
- 2011-04-12 DK DK11715645.5T patent/DK2558105T3/da active
- 2011-04-12 TW TW100112717A patent/TWI558724B/zh not_active IP Right Cessation
- 2011-04-12 BR BR112012026112-6A patent/BR112012026112B1/pt active IP Right Grant
- 2011-04-12 SG SG2012075834A patent/SG184830A1/en unknown
- 2011-04-12 EA EA201291031A patent/EA026567B1/ru not_active IP Right Cessation
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2012
- 2012-10-08 ZA ZA2012/07518A patent/ZA201207518B/en unknown
- 2012-10-09 IL IL222273A patent/IL222273B/en active IP Right Grant
- 2012-10-12 CL CL2012002859A patent/CL2012002859A1/es unknown
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2018
- 2018-09-13 US US16/130,242 patent/US11911395B2/en active Active
-
2019
- 2019-12-19 HR HRP20192291TT patent/HRP20192291T1/hr unknown
-
2020
- 2020-01-09 CY CY20201100022T patent/CY1122480T1/el unknown
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