RS52569B - Proces pripreme derivata ciklopropilamina - Google Patents

Proces pripreme derivata ciklopropilamina

Info

Publication number
RS52569B
RS52569B RS20120537A RSP20120537A RS52569B RS 52569 B RS52569 B RS 52569B RS 20120537 A RS20120537 A RS 20120537A RS P20120537 A RSP20120537 A RS P20120537A RS 52569 B RS52569 B RS 52569B
Authority
RS
Serbia
Prior art keywords
formula
compound
xxiiis
xxis
reacting
Prior art date
Application number
RS20120537A
Other languages
English (en)
Inventor
Neelakandha S. Mani
David C. Palmer
Chennagiri R. Pandit
Mayra B. Reyes
Tong Xiao
Sergio Cesco-Cancian
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of RS52569B publication Critical patent/RS52569B/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Proces za pripremanje jedinjenja formule (IIs)ili njegovog hidrara, solvata ili farmaceutski prihvatljive soli,koji obuhvatareakciju jedinjenja formule (XXs), u prvom organskom rastvaraču, da se dobije odgovarajuće jedinjenje formule (XXIs ), gde je L odlazeća grupa i gde jedinjenje formule (XXIs) nije izdvojeno;reakciju jedinjenja formule (XXIs) sa jedinjenjem formule (XXIIs), u prisustvu organske i neorganske baze, u drugom organskom rastvaraču, da se dobije odgovarajuće jedinjenje formule (XXIIIs), u kojoj jedinjenje formule ( XXIIIs) nije izdvojeno;i reakciju jedinjenja formule (XXIIIs) sa jedinjenjem formule (XXIVs), u prisustvu redukcionog sredstva, u trećem organskom rastvaraču. da se dobije odgovarajuće jedinjenje formule (IIs), gde su prvi, drugi i treći organski rastvarač isti i gde je L hloro.Prijava sadrži još 3 patentna zahteva.
RS20120537A 2005-10-31 2006-10-26 Proces pripreme derivata ciklopropilamina RS52569B (sr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73172505P 2005-10-31 2005-10-31
PCT/US2006/041590 WO2007053386A2 (en) 2005-10-31 2006-10-26 Processes for the preparation of cyclopropyl-amide derivatives

Publications (1)

Publication Number Publication Date
RS52569B true RS52569B (sr) 2013-04-30

Family

ID=38001898

Family Applications (1)

Application Number Title Priority Date Filing Date
RS20120537A RS52569B (sr) 2005-10-31 2006-10-26 Proces pripreme derivata ciklopropilamina

Country Status (29)

Country Link
EP (1) EP1951699B1 (sr)
JP (1) JP5185822B2 (sr)
KR (1) KR20080067362A (sr)
CN (2) CN101300242B (sr)
AR (2) AR058171A1 (sr)
AU (1) AU2006309124B2 (sr)
BR (1) BRPI0618076A2 (sr)
CA (2) CA2869539C (sr)
CR (1) CR10036A (sr)
DK (1) DK1951699T3 (sr)
EA (2) EA201001872A1 (sr)
EC (1) ECSP088417A (sr)
ES (1) ES2395049T3 (sr)
HK (1) HK1119676A1 (sr)
HR (1) HRP20121025T1 (sr)
IL (2) IL190965A (sr)
MX (1) MX367916B (sr)
MY (2) MY151028A (sr)
NO (1) NO340950B1 (sr)
NZ (2) NZ567359A (sr)
PL (1) PL1951699T3 (sr)
PT (1) PT1951699E (sr)
RS (1) RS52569B (sr)
SG (1) SG166803A1 (sr)
SI (1) SI1951699T1 (sr)
TW (1) TWI377201B (sr)
UA (1) UA93892C2 (sr)
WO (1) WO2007053386A2 (sr)
ZA (1) ZA200804730B (sr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0324159D0 (en) 2003-10-15 2003-11-19 Glaxo Group Ltd Novel compounds
TWI432422B (zh) 2007-08-22 2014-04-01 Astrazeneca Ab 環丙基醯胺衍生物
ATE554081T1 (de) 2007-09-06 2012-05-15 Glaxo Group Ltd Piperazinderivate mit affinität zum histamin-h3- rezeptor
TW201039825A (en) 2009-02-20 2010-11-16 Astrazeneca Ab Cyclopropyl amide derivatives 983
SG183274A1 (en) 2010-02-18 2012-09-27 Astrazeneca Ab Processes for making cyclopropyl amide derivatives and intermediates associated therewith
FR2962729B1 (fr) 2010-07-13 2012-09-21 Arkema France Molecules porteuses de groupes associatifs

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK5202000A3 (en) * 2000-04-07 2001-12-03 Slovakofarma As Method for the preparation of (e)-n-(6,6-dimethyl-2-hepten-4- inyl)-n-methyl-1-naphthalenemethylamine (terbinaphin)
ES2252250T3 (es) * 2000-07-05 2006-05-16 Basf Aktiengesellschaft Procedimiento para la obtencion de derivados de trioxima.
US20040010746A1 (en) 2002-07-10 2004-01-15 Lucas L. Victor Forward error correction system for wireless communications
SI1558595T1 (sl) 2002-10-23 2010-03-31 Janssen Pharmaceutica Nv Piperazinilni in diazapanilni benzamidi in benztioamidi
JP2007503440A (ja) * 2003-08-27 2007-02-22 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ アリールピペリジンアミド
CA2622760C (en) * 2005-09-16 2012-12-04 Janssen Pharmaceutica N.V. Cyclopropyl amines as modulators of the histamine h3 receptor

Also Published As

Publication number Publication date
PL1951699T3 (pl) 2013-03-29
HRP20121025T1 (hr) 2013-01-31
TW200736240A (en) 2007-10-01
SI1951699T1 (sl) 2013-01-31
EA200801240A1 (ru) 2008-08-29
CN101300242A (zh) 2008-11-05
JP5185822B2 (ja) 2013-04-17
CR10036A (es) 2009-02-23
AU2006309124B2 (en) 2013-02-14
NO20082458L (no) 2008-07-18
IL213474A0 (en) 2011-07-31
CA2628187A1 (en) 2007-05-10
IL190965A (en) 2014-04-30
NZ592864A (en) 2012-09-28
SG166803A1 (en) 2010-12-29
EP1951699A2 (en) 2008-08-06
CA2869539C (en) 2017-06-27
BRPI0618076A2 (pt) 2011-08-16
NZ567359A (en) 2011-07-29
EA201001872A1 (ru) 2011-04-29
ES2395049T3 (es) 2013-02-07
CN102659718A (zh) 2012-09-12
MX367916B (es) 2019-09-11
UA93892C2 (ru) 2011-03-25
CA2628187C (en) 2015-01-27
EA014935B1 (ru) 2011-04-29
KR20080067362A (ko) 2008-07-18
CN102659718B (zh) 2015-11-25
CN101300242B (zh) 2012-07-11
MY174411A (en) 2020-04-16
HK1119676A1 (en) 2009-03-13
EP1951699B1 (en) 2012-10-10
TWI377201B (en) 2012-11-21
AU2006309124A1 (en) 2007-05-10
MY151028A (en) 2014-03-31
DK1951699T3 (da) 2013-01-14
CA2869539A1 (en) 2007-05-10
IL213474A (en) 2014-05-28
PT1951699E (pt) 2012-12-26
NO340950B1 (no) 2017-07-24
AR114493A2 (es) 2020-09-09
AR058171A1 (es) 2008-01-23
WO2007053386A3 (en) 2007-11-01
WO2007053386A2 (en) 2007-05-10
JP2009513701A (ja) 2009-04-02
ZA200804730B (en) 2009-10-28
ECSP088417A (es) 2008-05-30
IL190965A0 (en) 2008-12-29

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