RS52492B - MOLECULES WHICH INTERSPECIALLY SPECIFICALLY BISPECIFICALLY Bind - Google Patents
MOLECULES WHICH INTERSPECIALLY SPECIFICALLY BISPECIFICALLY BindInfo
- Publication number
- RS52492B RS52492B RS20120412A RSP20120412A RS52492B RS 52492 B RS52492 B RS 52492B RS 20120412 A RS20120412 A RS 20120412A RS P20120412 A RSP20120412 A RS P20120412A RS 52492 B RS52492 B RS 52492B
- Authority
- RS
- Serbia
- Prior art keywords
- epitope
- species
- cross
- binding
- specific bispecific
- Prior art date
Links
- 239000011230 binding agent Substances 0.000 title 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 2
- 241000288950 Callithrix jacchus Species 0.000 abstract 1
- 101150029707 ERBB2 gene Proteins 0.000 abstract 1
- 101000946860 Homo sapiens T-cell surface glycoprotein CD3 epsilon chain Proteins 0.000 abstract 1
- 241000282577 Pan troglodytes Species 0.000 abstract 1
- 241000288906 Primates Species 0.000 abstract 1
- 241000288960 Saguinus oedipus Species 0.000 abstract 1
- 241000282696 Saimiri sciureus Species 0.000 abstract 1
- 102100035794 T-cell surface glycoprotein CD3 epsilon chain Human genes 0.000 abstract 1
- 102000052116 epidermal growth factor receptor activity proteins Human genes 0.000 abstract 1
- 108700015053 epidermal growth factor receptor activity proteins Proteins 0.000 abstract 1
- YOHYSYJDKVYCJI-UHFFFAOYSA-N n-[3-[[6-[3-(trifluoromethyl)anilino]pyrimidin-4-yl]amino]phenyl]cyclopropanecarboxamide Chemical compound FC(F)(F)C1=CC=CC(NC=2N=CN=C(NC=3C=C(NC(=O)C4CC4)C=CC=3)C=2)=C1 YOHYSYJDKVYCJI-UHFFFAOYSA-N 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Landscapes
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07006990 | 2007-04-03 | ||
| EP07006988 | 2007-04-03 | ||
| US91366807P | 2007-04-24 | 2007-04-24 | |
| EP07020641 | 2007-10-22 | ||
| EP07020640 | 2007-10-22 | ||
| EP07020646 | 2007-10-22 | ||
| EP08004741 | 2008-03-13 | ||
| PCT/EP2008/002663 WO2008119566A2 (en) | 2007-04-03 | 2008-04-03 | Cross-species-specific bispecific binders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RS52492B true RS52492B (en) | 2013-02-28 |
Family
ID=42582614
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RS20120412A RS52492B (en) | 2007-04-03 | 2008-04-03 | MOLECULES WHICH INTERSPECIALLY SPECIFICALLY BISPECIFICALLY Bind |
Country Status (8)
| Country | Link |
|---|---|
| JP (1) | JP2010524435A (enrdf_load_stackoverflow) |
| DK (1) | DK2155788T3 (enrdf_load_stackoverflow) |
| ES (1) | ES2390243T3 (enrdf_load_stackoverflow) |
| NZ (1) | NZ580746A (enrdf_load_stackoverflow) |
| PT (1) | PT2155788E (enrdf_load_stackoverflow) |
| RS (1) | RS52492B (enrdf_load_stackoverflow) |
| RU (1) | RU2535992C2 (enrdf_load_stackoverflow) |
| SI (1) | SI2155788T1 (enrdf_load_stackoverflow) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HRP20130883T4 (hr) * | 2007-04-03 | 2022-11-25 | Amgen Research (Munich) Gmbh | Međuvrsno specifična cd3-epsilon-vežuća domena |
| CN101675077B (zh) * | 2007-04-03 | 2013-09-04 | 安进研发（慕尼黑）股份有限公司 | 跨种特异性的双特异性结合剂 |
| EP2640750A1 (en) * | 2010-11-16 | 2013-09-25 | Boehringer Ingelheim International GmbH | Agents and methods for treating diseases that correlate with bcma expression |
| WO2012158818A2 (en) * | 2011-05-16 | 2012-11-22 | Fabion Pharmaceuticals, Inc. | Multi-specific fab fusion proteins and methods of use |
| CA2836857C (en) * | 2011-05-21 | 2019-12-03 | Macrogenics, Inc. | Cd3-binding molecules capable of binding to human and non-human cd3 |
| SI3736292T1 (sl) | 2013-12-17 | 2024-08-30 | Genentech, Inc. | Protitelesa proti CD3 in postopki uporabe |
| KR20170003591A (ko) * | 2014-05-28 | 2017-01-09 | 에프. 호프만-라 로슈 아게 | 인간 및 사이노몰구스 cd3 엡실론에 결합하는 항체 |
| JP7020909B2 (ja) * | 2014-07-25 | 2022-02-16 | シトムクス セラピューティクス，インコーポレイティド | 抗－ｃｄ３抗体、活性化可能抗－ｃｄ３抗体、多重特異的抗－ｃｄ３抗体、多重特異的活性化可能抗－ｃｄ３抗体、及びそれらの使用方法 |
| JP6698065B2 (ja) * | 2014-07-31 | 2020-05-27 | アムゲン リサーチ （ミュンヘン） ゲーエムベーハーＡＭＧＥＮ Ｒｅｓｅａｒｃｈ（Ｍｕｎｉｃｈ）ＧｍｂＨ | 組織分布が向上した二重特異性単鎖抗体コンストラクト |
| EP3778640A1 (en) * | 2015-05-01 | 2021-02-17 | Genentech, Inc. | Masked anti-cd3 antibodies and methods of use |
| AU2017233121B2 (en) | 2016-03-15 | 2023-12-21 | Itabmed (Hk) Limited | Multispecific Fab fusion proteins and use thereof |
| KR20190074300A (ko) | 2016-11-15 | 2019-06-27 | 제넨테크, 인크. | 항-cd20/항-cd3 이중특이적 항체에 의한 치료를 위한 투약 |
| US10426424B2 (en) | 2017-11-21 | 2019-10-01 | General Electric Company | System and method for generating and performing imaging protocol simulations |
| BR112020016169A2 (pt) | 2018-02-08 | 2020-12-15 | Genentech, Inc. | Moléculas de ligação ao antígeno biespecíficas, ácido nucleico isolado, vetor, célula hospedeira, métodos para produzir a molécula de ligação, conjunto de ácidos nucleicos isolados, conjunto de vetores, conjunto de células hospedeiras, imunoconjugado, composição, uso da molécula de ligação, métodos para tratar ou retardar a progressão de um câncer, métodos para aperfeiçoar a função imune e kit |
| US20230067182A1 (en) * | 2019-11-29 | 2023-03-02 | Boe Technology Group Co., Ltd. | Data Processing Device and Method, and Computer Readable Storage Medium |
| CN114867494B9 (zh) | 2019-12-13 | 2024-01-12 | 基因泰克公司 | 抗ly6g6d抗体及使用方法 |
| JP2022087602A (ja) * | 2020-12-01 | 2022-06-13 | 株式会社バイオピーク | 組換え大腸菌による有用タンパク質の生産性を向上するための培養方法 |
| AU2022273541A1 (en) | 2021-05-14 | 2023-11-30 | Genentech, Inc. | Methods for treatment of cd20-positive proliferative disorder with mosunetuzumab and polatuzumab vedotin |
| CN115932808B (zh) * | 2022-11-04 | 2025-05-27 | 四川九洲电器集团有限责任公司 | 一种基于多特征融合的被动声纳智能探测方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2179862C1 (ru) * | 2000-12-26 | 2002-02-27 | Общество с ограниченной ответственностью Научно-производственный центр "МедБиоСпектр" | Лекарственное средство для предотвращения отторжения трансплантата, моноклональное антитело к cd3-антигену т-лимфоцитов человека, гибридома и способ лечения больных, имеющих реакцию острого отторжения трансплантата после пересадки почки |
| RU2005137325A (ru) * | 2003-05-31 | 2006-09-10 | Микромет Аг (De) | Фармацевтическая композиция, содержащая конструкт, специфичный к ерсам |
| US7235641B2 (en) * | 2003-12-22 | 2007-06-26 | Micromet Ag | Bispecific antibodies |
| EP1753783B1 (en) * | 2004-06-03 | 2014-08-06 | Novimmune SA | Anti-cd3 antibodies and methods of use thereof |
| AU2006291005A1 (en) * | 2005-09-12 | 2007-03-22 | Novimmune S.A. | Anti-CD3 antibody formulations |
| US8236308B2 (en) * | 2005-10-11 | 2012-08-07 | Micromet Ag | Composition comprising cross-species-specific antibodies and uses thereof |
-
2008
- 2008-04-03 PT PT08735000T patent/PT2155788E/pt unknown
- 2008-04-03 RU RU2009136913/10A patent/RU2535992C2/ru active
- 2008-04-03 ES ES08735000T patent/ES2390243T3/es active Active
- 2008-04-03 RS RS20120412A patent/RS52492B/en unknown
- 2008-04-03 DK DK08735000.5T patent/DK2155788T3/da active
- 2008-04-03 JP JP2010501433A patent/JP2010524435A/ja not_active Revoked
- 2008-04-03 SI SI200830762T patent/SI2155788T1/sl unknown
- 2008-04-03 NZ NZ580746A patent/NZ580746A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NZ580746A (en) | 2012-05-25 |
| SI2155788T1 (sl) | 2012-11-30 |
| DK2155788T3 (da) | 2012-10-08 |
| ES2390243T3 (es) | 2012-11-07 |
| JP2010524435A (ja) | 2010-07-22 |
| PT2155788E (pt) | 2012-09-25 |
| RU2009136913A (ru) | 2011-06-20 |
| RU2535992C2 (ru) | 2014-12-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RS52492B (en) | MOLECULES WHICH INTERSPECIALLY SPECIFICALLY BISPECIFICALLY Bind | |
| RS53008B (en) | INTERSPECTION SPECIFIC CD3-EPSILON BINDING DOMAIN | |
| NZ602209A (en) | Cross-species-specific psmaxcd3 bispecific single chain antibody | |
| AR109355A2 (es) | Moléculas de unión al receptor ox40 humano | |
| RS53594B1 (en) | PREPARAT HER2 ANTITELA | |
| RS54675B1 (en) | MONOVALENT MIXTURES FOR CD28 BINDING AND METHODS OF USE | |
| TW200745164A (en) | Gene recombination antibodies composition | |
| EP2987806A3 (en) | Modified single variable domain antibodies with reduced binding to anti-drug-antibodies | |
| RU2019100481A (ru) | Биспецифические антитела-ингибиторы контрольных точек | |
| RU2014144143A (ru) | Химерные антигенные рецепторы, нацеленные на антиген созревания в-клеток | |
| RS54359B1 (en) | ANTI CD37 ANTIBODIES | |
| RS52484B (en) | CD40 ANTIBODIES | |
| EA200870555A1 (ru) | Слитые белки, их применение и способы их получения | |
| RU2013110875A (ru) | БИСПЕЦИФИЧЕСКИЕ АНТИТЕЛА, СОДЕРЖАЩИЕ СТАБИЛИЗИРОВАННЫЙ ДИСУЛЬФИДОМ ФРАГМЕНТ Fv | |
| CO5261584A1 (es) | Anticuerpos para il-1 humana | |
| NZ584838A (en) | Novel antibodies which bind alpha5beta1 (fibronectin receptor) and uses thereof | |
| NZ590668A (en) | TNF-alpha ANTAGONIST MULTI-TARGET BINDING PROTEINS | |
| DE602005022830D1 (de) | Weniger immunogene bindungsmoleküle | |
| NZ716762A (en) | Specific binding proteins and uses thereof | |
| RU2015147300A (ru) | Гуманизированные антитела к cxcr5, их производные и их применение | |
| RS54299B1 (en) | COMPOSITIONS AND METHODS OF USING THERAPY ANTIBODIES | |
| AR101936A1 (es) | Constructos de anticuerpos de cadena sencilla biespecífica específicos para especies cruzadas optimizadas | |
| MX377605B (es) | Inmunoglobulina híbrida conteniendo un enlace no-peptidílico. | |
| BRPI0410031A (pt) | variantes fc otimizadas e métodos para sua geração | |
| SG149004A1 (en) | Inhibitors of type 2 vascular endothelial growth factor receptors |