RO94160B - Procedeu de preparare a unor amide ale acidului lisergic - Google Patents
Procedeu de preparare a unor amide ale acidului lisergicInfo
- Publication number
- RO94160B RO94160B RO123579A RO12357986A RO94160B RO 94160 B RO94160 B RO 94160B RO 123579 A RO123579 A RO 123579A RO 12357986 A RO12357986 A RO 12357986A RO 94160 B RO94160 B RO 94160B
- Authority
- RO
- Romania
- Prior art keywords
- amides
- preparing
- page
- optionally
- general formula
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 2
- 150000001408 amides Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 abstract 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- ZAGRKAFMISFKIO-UHFFFAOYSA-N Isolysergic acid Natural products C1=CC(C2=CC(CN(C2C2)C)C(O)=O)=C3C2=CNC3=C1 ZAGRKAFMISFKIO-UHFFFAOYSA-N 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000001805 chlorine compounds Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- ZAGRKAFMISFKIO-QMTHXVAHSA-N lysergic acid Chemical compound C1=CC(C2=C[C@H](CN([C@@H]2C2)C)C(O)=O)=C3C2=CNC3=C1 ZAGRKAFMISFKIO-QMTHXVAHSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000009466 transformation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
- C07D457/06—Lysergic acid amides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DD27717585A DD238051A1 (de) | 1985-06-10 | 1985-06-10 | Verfahren zur herstellung neuer lysergsaeureamide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RO94160A RO94160A (ro) | 1988-03-30 |
| RO94160B true RO94160B (ro) | 1988-03-31 |
Family
ID=5568455
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RO123579A RO94160B (ro) | 1985-06-10 | 1986-06-02 | Procedeu de preparare a unor amide ale acidului lisergic |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0205068B1 (en, 2012) |
| BG (1) | BG44609A1 (en, 2012) |
| CS (1) | CS260497B1 (en, 2012) |
| DD (1) | DD238051A1 (en, 2012) |
| DE (1) | DE3683190D1 (en, 2012) |
| HU (1) | HU196398B (en, 2012) |
| PL (1) | PL149497B1 (en, 2012) |
| RO (1) | RO94160B (en, 2012) |
| SU (1) | SU1481233A1 (en, 2012) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL311602A (en) * | 2021-09-20 | 2024-05-01 | Betterlife Pharma Inc | Lsd derivatives, synthesis & method for treatment of diseases and disorders |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3239530A (en) * | 1964-01-13 | 1966-03-08 | Sandoz Ltd | Process for lysergic acid hydrazides |
| HU169073B (en, 2012) * | 1974-05-28 | 1976-09-28 | ||
| DD146460A1 (de) * | 1979-11-14 | 1981-02-11 | Reni Bartsch | Verfahren zur herstellung 1-benzylierter ergometrinderivate |
| DE3340025C2 (de) * | 1983-11-03 | 1986-01-09 | Schering AG, 1000 Berlin und 4709 Bergkamen | Verfahren zur Herstellung von 2-Brom-8-ergolinyl-Verbindungen |
-
1985
- 1985-06-10 DD DD27717585A patent/DD238051A1/de not_active IP Right Cessation
-
1986
- 1986-05-14 SU SU864027468A patent/SU1481233A1/ru active
- 1986-06-02 RO RO123579A patent/RO94160B/ro unknown
- 1986-06-02 EP EP86107482A patent/EP0205068B1/de not_active Expired - Lifetime
- 1986-06-02 DE DE8686107482T patent/DE3683190D1/de not_active Expired - Lifetime
- 1986-06-03 CS CS864066A patent/CS260497B1/cs unknown
- 1986-06-04 BG BG7522886A patent/BG44609A1/xx unknown
- 1986-06-06 PL PL25994486A patent/PL149497B1/pl unknown
- 1986-06-09 HU HU243586A patent/HU196398B/hu not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PL149497B1 (en) | 1990-02-28 |
| HU196398B (en) | 1988-11-28 |
| SU1481233A1 (ru) | 1989-05-23 |
| HUT43038A (en) | 1987-09-28 |
| EP0205068A3 (en) | 1988-01-13 |
| CS260497B1 (en) | 1988-12-15 |
| RO94160A (ro) | 1988-03-30 |
| BG44609A1 (en, 2012) | 1989-01-16 |
| DD238051A1 (de) | 1986-08-06 |
| EP0205068A2 (de) | 1986-12-17 |
| EP0205068B1 (de) | 1992-01-02 |
| CS406686A1 (en) | 1988-05-16 |
| DE3683190D1 (de) | 1992-02-13 |
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