FI881040A0 - Foerfarande foer framstaellning av kristallisk cefadroxil-monohydrat. - Google Patents
Foerfarande foer framstaellning av kristallisk cefadroxil-monohydrat.Info
- Publication number
- FI881040A0 FI881040A0 FI881040A FI881040A FI881040A0 FI 881040 A0 FI881040 A0 FI 881040A0 FI 881040 A FI881040 A FI 881040A FI 881040 A FI881040 A FI 881040A FI 881040 A0 FI881040 A0 FI 881040A0
- Authority
- FI
- Finland
- Prior art keywords
- cefadroxil
- monohydrate
- freezing
- crystalline
- cefadroxyl monohydrate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/080,999 US4898938A (en) | 1987-08-03 | 1987-08-03 | Method for preparing crystalline cefadroxil monohydrate |
US8099987 | 1987-08-03 |
Publications (4)
Publication Number | Publication Date |
---|---|
FI881040A0 true FI881040A0 (fi) | 1988-03-07 |
FI881040A FI881040A (fi) | 1989-02-04 |
FI88043B FI88043B (fi) | 1992-12-15 |
FI88043C FI88043C (fi) | 1993-03-25 |
Family
ID=22161022
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI881040A FI88043C (fi) | 1987-08-03 | 1988-03-07 | Foerfarande foer framstaellning av kristalliskt cefadroxilmonohydrat |
Country Status (18)
Country | Link |
---|---|
US (1) | US4898938A (fi) |
EP (1) | EP0302145B1 (fi) |
JP (1) | JP2655664B2 (fi) |
KR (1) | KR960002910B1 (fi) |
CN (1) | CN1016607B (fi) |
AT (1) | ATE105560T1 (fi) |
AU (1) | AU597136B2 (fi) |
CA (1) | CA1285554C (fi) |
DE (1) | DE3789810T2 (fi) |
DK (1) | DK680387A (fi) |
ES (1) | ES2056059T3 (fi) |
FI (1) | FI88043C (fi) |
NO (1) | NO168425C (fi) |
PH (1) | PH23648A (fi) |
PT (1) | PT86526B (fi) |
RU (1) | RU1804461C (fi) |
YU (1) | YU44649B (fi) |
ZA (1) | ZA879701B (fi) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991000865A1 (en) * | 1989-07-10 | 1991-01-24 | Gema S.A. | A novel stable form of cephradine, process for its production and intermediates used therein |
US5589593A (en) * | 1991-11-11 | 1996-12-31 | Biochimica Opos Spa | Crystalline form of a cephalosporin antibiotic |
IT1251999B (it) * | 1991-11-11 | 1995-05-27 | Opos Biochimica Srl | Forma cristallina di un antibiotico cefalosporinico |
JP2005530746A (ja) * | 2002-05-03 | 2005-10-13 | エスビー・ファルムコ・プエルト・リコ・インコーポレイテッド | カルベジロールファーマソルブ溶媒和物 |
US20040077849A1 (en) * | 2002-10-16 | 2004-04-22 | Orchid Chemicals & Pharmaceuticals Limited | Process for the preparation of cefadroxil |
US7842791B2 (en) * | 2002-12-19 | 2010-11-30 | Nancy Jean Britten | Dispersible pharmaceutical compositions |
CN1311830C (zh) * | 2004-02-27 | 2007-04-25 | 石药集团中奇制药技术(石家庄)有限公司 | 头孢羟氨苄口腔崩解片及其制备方法 |
KR101420451B1 (ko) * | 2006-05-19 | 2014-07-16 | 디에스엠 시노켐 파마슈티칼스 네덜란드 비.브이. | 세파드록실의 결정화 방법 |
CN102134250B (zh) * | 2011-01-19 | 2013-03-13 | 天津大学 | 一种头孢羟氨苄单水合物的结晶方法及结晶 |
CN104447795B (zh) * | 2014-11-28 | 2016-08-17 | 珠海金鸿药业股份有限公司 | 一种头孢羟氨苄化合物及其药物组合物 |
CN105534937B (zh) * | 2015-12-30 | 2019-12-03 | 石药集团欧意药业有限公司 | 一种头孢羟氨苄片剂及其制备方法 |
CN106588953B (zh) * | 2016-11-08 | 2018-11-27 | 山东罗欣药业集团恒欣药业有限公司 | 一种抗感染药物头孢羟氨苄晶型化合物及其组合物 |
CN106588954B (zh) * | 2016-11-08 | 2018-11-27 | 山东罗欣药业集团恒欣药业有限公司 | 一种抗感染药物羟氨苄晶体化合物及其组合物 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1532682A (en) * | 1976-04-27 | 1978-11-22 | Bristol Myers Co | Process for the preparation of cephadroxil |
US4160863A (en) * | 1977-04-07 | 1979-07-10 | Bristol-Myers Company | Process for the preparation of the crystalline monohydrate of 7-[D-α-aα-(p-hydroxyphenyl)acetamido]-3-methyl-3-cephem-4-carboxylic acid |
GB8714180D0 (en) * | 1987-06-17 | 1987-07-22 | Rifar Srl | Anhydrous crystalline cefadroxil |
WO1988008320A1 (en) * | 1987-04-24 | 1988-11-03 | Invenmark Limited | Puzzle |
-
1987
- 1987-08-03 US US07/080,999 patent/US4898938A/en not_active Expired - Fee Related
- 1987-12-22 AT AT8787119079T patent/ATE105560T1/de not_active IP Right Cessation
- 1987-12-22 ES ES87119079T patent/ES2056059T3/es not_active Expired - Lifetime
- 1987-12-22 DK DK680387A patent/DK680387A/da not_active Application Discontinuation
- 1987-12-22 DE DE3789810T patent/DE3789810T2/de not_active Expired - Fee Related
- 1987-12-22 EP EP87119079A patent/EP0302145B1/en not_active Expired - Lifetime
- 1987-12-24 AU AU83045/87A patent/AU597136B2/en not_active Ceased
- 1987-12-28 ZA ZA879701A patent/ZA879701B/xx unknown
- 1987-12-29 YU YU2427/87A patent/YU44649B/xx unknown
- 1987-12-30 CA CA000555571A patent/CA1285554C/en not_active Expired - Lifetime
-
1988
- 1988-01-05 NO NO880026A patent/NO168425C/no unknown
- 1988-01-11 KR KR1019880000123A patent/KR960002910B1/ko not_active IP Right Cessation
- 1988-01-11 PT PT86526A patent/PT86526B/pt not_active IP Right Cessation
- 1988-01-18 RU SU884204000A patent/RU1804461C/ru active
- 1988-02-04 JP JP63024868A patent/JP2655664B2/ja not_active Expired - Lifetime
- 1988-02-10 CN CN88100573A patent/CN1016607B/zh not_active Expired
- 1988-03-07 FI FI881040A patent/FI88043C/fi not_active IP Right Cessation
- 1988-04-04 PH PH36730A patent/PH23648A/en unknown
Also Published As
Publication number | Publication date |
---|---|
AU597136B2 (en) | 1990-05-24 |
PT86526A (pt) | 1989-09-14 |
DK680387A (da) | 1989-02-04 |
EP0302145B1 (en) | 1994-05-11 |
DK680387D0 (da) | 1987-12-22 |
CN1031085A (zh) | 1989-02-15 |
PT86526B (pt) | 1994-10-31 |
NO880026L (no) | 1989-02-06 |
NO168425B (no) | 1991-11-11 |
EP0302145A2 (en) | 1989-02-08 |
JPS6442487A (en) | 1989-02-14 |
DE3789810D1 (de) | 1994-06-16 |
ATE105560T1 (de) | 1994-05-15 |
CN1016607B (zh) | 1992-05-13 |
AU8304587A (en) | 1989-02-09 |
DE3789810T2 (de) | 1994-08-18 |
FI88043B (fi) | 1992-12-15 |
PH23648A (en) | 1989-09-27 |
FI881040A (fi) | 1989-02-04 |
NO880026D0 (no) | 1988-01-05 |
NO168425C (no) | 1992-02-19 |
CA1285554C (en) | 1991-07-02 |
YU242787A (en) | 1989-02-28 |
US4898938A (en) | 1990-02-06 |
FI88043C (fi) | 1993-03-25 |
ES2056059T3 (es) | 1994-10-01 |
KR960002910B1 (ko) | 1996-02-28 |
KR890003775A (ko) | 1989-04-18 |
ZA879701B (en) | 1988-06-23 |
YU44649B (en) | 1990-10-31 |
JP2655664B2 (ja) | 1997-09-24 |
EP0302145A3 (en) | 1989-08-23 |
RU1804461C (ru) | 1993-03-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM | Patent lapsed | ||
MM | Patent lapsed |
Owner name: RIFAR S.R.L. |