ZA879701B - Method for preparing crystalline cefadroxil monohydrate - Google Patents

Method for preparing crystalline cefadroxil monohydrate

Info

Publication number
ZA879701B
ZA879701B ZA879701A ZA879701A ZA879701B ZA 879701 B ZA879701 B ZA 879701B ZA 879701 A ZA879701 A ZA 879701A ZA 879701 A ZA879701 A ZA 879701A ZA 879701 B ZA879701 B ZA 879701B
Authority
ZA
South Africa
Prior art keywords
cefadroxil
preparing crystalline
monohydrate
cefadroxil monohydrate
crystalline cefadroxil
Prior art date
Application number
ZA879701A
Other languages
English (en)
Inventor
Marsili Leonardo
Original Assignee
Rifar S.R.L.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rifar S.R.L. filed Critical Rifar S.R.L.
Publication of ZA879701B publication Critical patent/ZA879701B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA879701A 1987-08-03 1987-12-28 Method for preparing crystalline cefadroxil monohydrate ZA879701B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/080,999 US4898938A (en) 1987-08-03 1987-08-03 Method for preparing crystalline cefadroxil monohydrate

Publications (1)

Publication Number Publication Date
ZA879701B true ZA879701B (en) 1988-06-23

Family

ID=22161022

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA879701A ZA879701B (en) 1987-08-03 1987-12-28 Method for preparing crystalline cefadroxil monohydrate

Country Status (18)

Country Link
US (1) US4898938A (xx)
EP (1) EP0302145B1 (xx)
JP (1) JP2655664B2 (xx)
KR (1) KR960002910B1 (xx)
CN (1) CN1016607B (xx)
AT (1) ATE105560T1 (xx)
AU (1) AU597136B2 (xx)
CA (1) CA1285554C (xx)
DE (1) DE3789810T2 (xx)
DK (1) DK680387A (xx)
ES (1) ES2056059T3 (xx)
FI (1) FI88043C (xx)
NO (1) NO168425C (xx)
PH (1) PH23648A (xx)
PT (1) PT86526B (xx)
RU (1) RU1804461C (xx)
YU (1) YU44649B (xx)
ZA (1) ZA879701B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0433428B1 (en) * 1989-07-10 1994-10-12 Chemferm V.O.F. A stable form of cephradine, process for its production and intermediates used therein
IT1251999B (it) * 1991-11-11 1995-05-27 Opos Biochimica Srl Forma cristallina di un antibiotico cefalosporinico
US5589593A (en) * 1991-11-11 1996-12-31 Biochimica Opos Spa Crystalline form of a cephalosporin antibiotic
CA2484624A1 (en) * 2002-05-03 2003-11-13 Smithkline Beecham Pharmco Puerto Rico, Inc. Carvedilol pharmasolve solvate
US20040077849A1 (en) * 2002-10-16 2004-04-22 Orchid Chemicals & Pharmaceuticals Limited Process for the preparation of cefadroxil
US7842791B2 (en) * 2002-12-19 2010-11-30 Nancy Jean Britten Dispersible pharmaceutical compositions
CN1311830C (zh) * 2004-02-27 2007-04-25 石药集团中奇制药技术（石家庄）有限公司 头孢羟氨苄口腔崩解片及其制备方法
MX2008014711A (es) * 2006-05-19 2008-12-03 Dsm Ip Assets Bv Procedimiento para la cristalizacion de cefadroxilo.
CN102134250B (zh) * 2011-01-19 2013-03-13 天津大学 一种头孢羟氨苄单水合物的结晶方法及结晶
CN104447795B (zh) * 2014-11-28 2016-08-17 珠海金鸿药业股份有限公司 一种头孢羟氨苄化合物及其药物组合物
CN105534937B (zh) * 2015-12-30 2019-12-03 石药集团欧意药业有限公司 一种头孢羟氨苄片剂及其制备方法
CN106588954B (zh) * 2016-11-08 2018-11-27 山东罗欣药业集团恒欣药业有限公司 一种抗感染药物羟氨苄晶体化合物及其组合物
CN106588953B (zh) * 2016-11-08 2018-11-27 山东罗欣药业集团恒欣药业有限公司 一种抗感染药物头孢羟氨苄晶型化合物及其组合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1532682A (en) * 1976-04-27 1978-11-22 Bristol Myers Co Process for the preparation of cephadroxil
US4160863A (en) * 1977-04-07 1979-07-10 Bristol-Myers Company Process for the preparation of the crystalline monohydrate of 7-[D-α-aα-(p-hydroxyphenyl)acetamido]-3-methyl-3-cephem-4-carboxylic acid
GB8714180D0 (en) * 1987-06-17 1987-07-22 Rifar Srl Anhydrous crystalline cefadroxil
AU1628588A (en) * 1987-04-24 1988-12-02 Invenmark Limited Puzzle

Also Published As

Publication number Publication date
CA1285554C (en) 1991-07-02
JP2655664B2 (ja) 1997-09-24
DE3789810D1 (de) 1994-06-16
FI88043B (fi) 1992-12-15
DE3789810T2 (de) 1994-08-18
PT86526A (pt) 1989-09-14
JPS6442487A (en) 1989-02-14
PH23648A (en) 1989-09-27
EP0302145A3 (en) 1989-08-23
AU8304587A (en) 1989-02-09
FI881040A (fi) 1989-02-04
NO168425C (no) 1992-02-19
FI881040A0 (fi) 1988-03-07
DK680387A (da) 1989-02-04
US4898938A (en) 1990-02-06
AU597136B2 (en) 1990-05-24
NO880026L (no) 1989-02-06
EP0302145A2 (en) 1989-02-08
NO168425B (no) 1991-11-11
YU242787A (en) 1989-02-28
NO880026D0 (no) 1988-01-05
RU1804461C (ru) 1993-03-23
KR890003775A (ko) 1989-04-18
FI88043C (fi) 1993-03-25
YU44649B (en) 1990-10-31
ES2056059T3 (es) 1994-10-01
EP0302145B1 (en) 1994-05-11
ATE105560T1 (de) 1994-05-15
CN1031085A (zh) 1989-02-15
CN1016607B (zh) 1992-05-13
KR960002910B1 (ko) 1996-02-28
PT86526B (pt) 1994-10-31
DK680387D0 (da) 1987-12-22

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